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BCRXBioCryst Pharmaceuticals, Inc.
$7.69$2.0B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
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BCRX logo

BioCryst Pharmaceuticals, Inc.

BCRX
NASDAQ · Rare Disease Biotech
$7.69
At close - Nov 6, 4:00 PM EST - USD
Market Cap$1.95B
P/E-5.7x
52W High$11.22
Volume5.21M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Orladeyo Scaling Drives Margin Expansion Amid Debt

BioCryst's revenue growth is accelerating, with Q2 2026 revenue up 33.6% sequentially to $218.2M, driven by Orladeyo uptake. Gross margins remain above 98%, and operating leverage has expanded operating margin to 45.1% in Q2 2026 from -15.6% in Q1 2024.

GrowthAccelerating
ProfitabilityStrong
ValuationAttractive
TechnicalsWeak
Explore valuation models
MARKET ACTION

BCRX price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

6/12 Beats

EPS beat 6 of last 12 quarters

02

Valuation risk

-116% Peers

P/E is 116% below peer median

03

Market leadership

RS 34 · Lag

Laggard (Underperforming 66% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 4

Market performance

Price History →

Trailing total returns as of 11/9/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
BCRX+2.53%
S&P 500 (^GSPC)+7.63%
1-Year Return
BCRX+9.39%
S&P 500 (^GSPC)+9.69%
3-Year Return
BCRX+29.68%
S&P 500 (^GSPC)+69.98%
5-Year Return
BCRX-37.07%
S&P 500 (^GSPC)+57.83%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/E5Y Low
-5.7x
Forward P/E
N/A
EV/EBITDA
N/A
FCF YieldCash Flow
17.9%

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
-5.7x
6.4x
0th· Low
EV/EBITDA
N/A
6.0x
N/A
Price/FCF
5.6x
5.2x
100th· High
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
No DCF Model AvailableIntrinsic value modeling is not supported for this equity.

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$875M+94.1% YoY
Net income FY25
$264M+396.9% YoY
Free cash flow FY25
$327M+716.1% YoY
Operating margin FY25
39%+39.5 pts YoY
ROIC (FY25)104.3%
Avg ROIC 5Y-28.7%
ROE (FY25)-
Piotroski Score7 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate6/12 (50%)
Revenue Beat Rate10/12 (83%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 4, 2026
$0.14+52.4%
vs $0.09
$180M+8.8%
vs $166M
Q3 2026
Aug 5, 2026
$0.30+94.6%
vs $0.15
$218M+19.1%
vs $183M
Q2 2026
May 6, 2026
-$2.98-5066.7%
vs $0.06
$156M+3.5%
vs $151M
Q1 2026
Feb 26, 2026
$1.12+1500.0%
vs $0.07
$407M+168.7%
vs $151M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Defense World·3d ago
Head-To-Head Review: BioCryst Pharmaceuticals (NASDAQ:BCRX) & Zenas BioPharma (NASDAQ:ZBIO)

BioCryst Pharmaceuticals (NASDAQ: BCRX - Get Free Report) and Zenas BioPharma (NASDAQ: ZBIO - Get Free Report) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their earnings, profitability, dividends, valuation, analyst recommendations, institutional ownership and risk. Risk and Volatility BioCryst Pharmaceuticals has a beta

Seeking Alpha·4d ago
BioCryst Pharmaceuticals, Inc. (BCRX) Q3 2026 Earnings Call Transcript

BioCryst Pharmaceuticals, Inc. ( BCRX ) Q3 2026 Earnings Call November 4, 2026 8:30 AM EST Company Participants Nick Wilder - Manager of Investor Relations Charles Gayer - CEO, President & Director Babar Ghias - CFO & Head of Corporate Development Sandeep Menon - Chief Research & Development Officer Conference Call Participants Gavin Clark-Gartner - Evercore ISI Institutional Equities, Research Division Laura Chico - Wedbush Securities Inc., Research Division Steven Seedhouse - Cantor Fitzgerald & Co., Research Division Stacy Ku - TD Cowen, Research Division Jeremiah Lorentz - BofA Securities, Research Division Maurice Raycroft - Jefferies LLC, Research Division John Todaro - Needham & Company, LLC, Research Division Catherine Okoukoni - Citizens JMP Securities, LLC, Research Division Brian Abrahams - RBC Capital Markets, Research Division Presentation Operator Good day, and thank you for standing by. Welcome to the BioCryst Third Quarter 2026 Earnings Call.

Seeking Alpha·4d ago
BioCryst: Solid Q3 Earnings, But Long-Acting HAE Data Due 2027 The Key Catalyst

BioCryst Pharmaceuticals delivered Q3 2026 results ahead of expectations, maintaining 2026 guidance and highlighting Orladeyo's ongoing growth in a competitive HAE market. BCRX's valuation appears modest at ~3.5x forward P/S and ~11x forward P/E (excluding IPR&D), but future upside depends on pipeline execution, especially navenibart. Management pivots to external innovation, targeting >$1bn revenues by 2030 with Orladeyo, navenibart, and BCX17725, while royalty burdens are set to ease after 2029.

MarketBeat·4d ago
BioCryst Pharmaceuticals Q3 Earnings Call Highlights

BioCryst Pharmaceuticals NASDAQ: BCRX reported third-quarter results marked by growth in ORLADEYO revenue, higher profitability and progress across its hereditary angioedema, or HAE, portfolio, while maintaining its full-year ORLADEYO revenue outlook following a specialty-pharmacy transition.

Filtered for BioCryst Pharmaceuticals, Inc.More Headlines
04

Compare before deciding

Benchmark BCRX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for BioCryst Pharmaceuticals, Inc. (BCRX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
BCRX logoBCRXBioCryst Pharmaceuticals, Inc.Current
$7.69$1.95B-5.7294.1%-37.41%——
RARE logoRAREUltragenyx Pharmaceutical Inc.
$15.43$1.52B-3.0120.13%-71.78%——
ACAD logoACADACADIA Pharmaceuticals Inc.
$21.23$3.64B10.2811.87%30.13%28.03%—
PTCT logoPTCTPTC Therapeutics, Inc.
$65.44$5.43B-51.55114.51%-9.17%——
KYMR logoKYMRKymera Therapeutics, Inc.
$131.73$10.84B-37.73-16.72%-341.87%-22.39%—
ARGX logoARGXargenx SE
$927.21$60.16B47.2389.64%———

Compare BCRX vs Peers

BioCryst Pharmaceuticals, Inc. (BCRX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RARE

Most directly comparable listed peer for BCRX.

Scale Benchmark

vs ARGX

Larger-name benchmark to compare BCRX against a more recognizable public peer.

Peer Set

Compare Top 5

vs RARE, ACAD, PTCT, KYMR

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

BCRX SEC Filings & Documents

BioCryst Pharmaceuticals, Inc. (BCRX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 5, 2026·SEC

Material company update

Jun 29, 2026·SEC

Material company update

Jun 12, 2026·SEC

10-K Annual Reports

2
FY 2026

Feb 26, 2026·SEC

FY 2025

Feb 25, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 5, 2026·SEC

FY 2026

May 6, 2026·SEC

FY 2025

Nov 4, 2025·SEC

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BCRX Frequently Asked Questions

BioCryst Pharmaceuticals, Inc. (BCRX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is BioCryst Pharmaceuticals, Inc.'s revenue?

BioCryst Pharmaceuticals, Inc. (BCRX) reported $961.5M in revenue over the trailing twelve months. Revenue was $874.8M in fiscal year 2025. That is 32301% more than the $2.7M of fiscal year 1996.

How fast is BioCryst Pharmaceuticals, Inc. growing?

BioCryst Pharmaceuticals, Inc. (BCRX) grew revenue by 60.3% over the trailing twelve months, compared with the twelve months before.

Is BCRX profitable?

No. BioCryst Pharmaceuticals, Inc. (BCRX) reported a net loss of $359.7M over the trailing twelve months.

Dividend & Returns
What is BioCryst Pharmaceuticals, Inc.'s free cash flow?

BioCryst Pharmaceuticals, Inc. (BCRX) generated $349.6M in free cash flow over the trailing twelve months.

What if you invested $1,000 in BCRX back in 1996?

Total return calculator · dividends reinvested · 30+ years of data

See returns →