Cash conversion remains erratic, evidenced by a 2022Q4 OCF/NI ratio of 7.45, which highlights the company's historical reliance on external capital to fund operations.
| Metric | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 |
|---|
| Cash from Operations | 31.63M | 49.6M | -35.89M | -33.92M | -23.22M | -28.32M | -27.89M | -13.29M | -30.66M | -19.82M | -25.61M | -11.15M | -6.44M | -10.85M | -9.25M | -4.28M | -7.45M | -10.01M | -8.41M | -9.93M | -11.11M | -12.2M | -5.57M | -9.08M | -9.5M | -6.14M | -5.76M |
| Operating CF Margin % | 43.47% | 178.02% | -107.25% | -452.29% | -386.98% | -1416% | - | -74.67% | - | -2783.57% | -276.03% | -90.14% | -181.43% | -4481.82% | 2181.37% | -383.77% | -2981.2% | -2962.13% | -4670.56% | -4620% | -1719.5% | -303% | -63.14% | -81.79% | -83.6% | -89.12% | -178.04% |
| Operating CF Growth % | -36.23% | 238.23% | -5.79% | -46.1% | 18.01% | -1.55% | -109.83% | 56.65% | -54.69% | 22.6% | -129.7% | -73.13% | 40.63% | -17.27% | -116.15% | 42.59% | 25.56% | -19.09% | 15.36% | 10.58% | 8.97% | -118.95% | 38.6% | 4.43% | -54.65% | -6.56% | - |
| Net Income | 35.34M | -14.23M | -18.75M | -33.69M | -34.2M | -29.7M | -27.34M | -22.6M | -37.07M | -31.51M | -20.16M | -11.09M | -14.08M | -13.63M | -12M | -7.2M | -3.84M | -12.51M | -12.11M | -13.02M | -13.98M | -13.72M | -11.44M | -12.2M | -15.14M | -13.4M | -8.13M |
| Depreciation & Amortization | 475K | 486K | 476K | 482K | 461K | 715K | 989K | 1.39M | 1.59M | 1.48M | 1.11M | 658K | 370K | 299K | 179K | 201K | 264K | 477K | 633K | 996K | 2.39M | 1.76M | 2.67M | 2.9M | 4.28M | 4.99M | 1.86M |
| Stock-Based Compensation | 0 | 3.02M | 3.55M | 4.33M | 4.28M | 2.77M | 2.41M | 2.17M | 2.63M | 3.08M | 3.77M | 3.63M | 3.54M | 2.47M | 3.4M | 2.34M | 1.53M | 1.8M | 0 | 0 | 0 | 786K | 786K | 2.59M | 0 | 0 | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | -12K | -135K | 52K | 0 | -383K | -279K | -2.67M | -2.94M | 643K | -126K | -419K | -3.85M | 117K | 0 | 0 | 0 | -786K | -786K | -2.59M | 0 | 0 | 0 |
| Other Non-Cash Items | 1.16M | -1.72M | -452K | 515K | -573K | 184K | -22K | 46K | -33K | 101K | -421K | 455K | -230K | -130K | -7K | 164K | -88K | 31K | 3.44M | 2.27M | 197K | 1.66M | 723K | 932K | 54K | 2.05M | 1.16M |
| Working Capital Changes | -5.35M | 62.05M | -20.71M | -5.55M | 6.82M | -2.28M | -3.79M | 5.65M | 2.21M | 7.4M | -9.62M | -2.13M | 6.91M | -499K | -691K | 641K | -1.46M | 71K | -370K | -181K | 287K | -1.9M | 2.47M | -702K | 1.32M | 220K | -657K |
| Change in Receivables | 360K | 59.93M | -61.11M | 3.04M | 2M | -2M | -142K | -179K | 422K | 7.8M | -7.8M | 1.03M | -1.1M | -112K | 43K | -21K | 58K | 222K | 0 | 0 | 0 | 1.61M | 1.61M | 81K | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | -3.37M | -3.82M | 3.5M | -954K | 247K | 518K | -1.17M | 152K | 202K | 0 | 734K | 213K | 0 | 0 | 0 | 0 | 0 | 80K | 80K | 23K | 42K | -5K | 165K |
| Change in Payables | 517K | -4.41M | 3.51M | -1.6M | 3.37M | 3.82M | -3.5M | 2.69M | 1.56M | -605K | 823K | 1.67M | 1.04M | -86K | -734K | 562K | -1.53M | 0 | 0 | 0 | 0 | -796K | -796K | 1.77M | 0 | 0 | 0 |
| Cash from Investing | 30M | -46.25M | 35.51M | 37.06M | 6.62M | -82.17M | 5.33M | -35.16M | 46.27M | 16.29M | 9.77M | -64.09M | -11.57M | 12.26M | -1.23M | -13.67M | 5.73M | 13.12M | 3.16M | 7.03M | 15.06M | 5.93M | 4.85M | 5.77M | -62.84M | -12.07M | -1.8M |
| Capital Expenditures | -306K | -118K | -172K | -487K | -292K | -166K | -155K | -158K | -385K | -2.6M | -3.12M | -1.9M | -328K | -1M | -96K | -46K | -48K | -120K | -205K | -161K | -862K | -1.44M | -2.33M | -1.43M | -2.77M | -2.03M | -1.8M |
| CapEx % of Revenue | 0.42% | 0.42% | 0.51% | 6.49% | 4.87% | 8.3% | - | 0.89% | - | 365.03% | 33.63% | 15.33% | 9.24% | 415.29% | -22.64% | 4.13% | 19.2% | 35.5% | 113.89% | 74.88% | 133.44% | 35.63% | 26.35% | 12.85% | 24.34% | 29.52% | 55.61% |
| Acquisitions | 1K | 0 | 0 | 2K | 3K | 44K | 382K | 2K | -46.66M | 0 | 423K | 2.31M | 3.6M | 0 | 232K | 25K | 185K | 0 | 1K | 82K | 0 | 0 | 30.2M | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | -329K | 0 | 0 | 0 | 0 | 0 | 2K | 46.66M | 84K | -534K | -491K | -50K | -42K | 639K | -47K | -96K | 14K | 7K | -11.96M | 409K | -7K | -1.28M | -19K | -30.64M | -32K | -3K |
| Cash from Financing | 10.6M | 554K | 3.08M | 353K | 16.84M | 108.46M | 25.93M | 28.4M | 201K | 2.46M | 972K | 72.13M | 30.39M | 9.11M | 9.02M | 10.11M | 12.21M | 295K | 295K | 665K | 178K | 2.73M | 3.34M | 161K | 104K | 87.45M | -939K |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.04M | 0 | 0 | 0 | -958K |
| Equity Issued (Net) | 10.61M | 544K | 3.08M | 353K | 14.96M | 74.15M | 22.76M | 27.71M | 0 | 0 | 0 | 70.72M | 19.76M | 6.21M | 0 | 7.79M | 12.01M | 0 | 295K | 665K | 178K | 2.73M | 1.31M | 161K | 104K | 87.45M | 19K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -4K | 10K | 0 | 0 | 1.88M | 34.32M | 3.17M | 685K | 201K | 2.46M | 972K | 1.41M | 10.63M | 2.9M | 9.02M | 2.32M | 196K | 295K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Net Change in Cash | 72.37M | 3.97M | 2.83M | 2.91M | 704K | -2.03M | 3.37M | -20.05M | 15.82M | -1.07M | -14.87M | -3.11M | 12.38M | 10.53M | -1.45M | -7.84M | 10.49M | 3.35M | -4.95M | -2.24M | 4.13M | -3.54M | 2.62M | -3.15M | -72.24M | 69.24M | -8.51M |
| Free Cash Flow | 31.33M | 49.49M | -36.06M | -34.99M | -23.04M | -28.49M | -28.04M | -13.45M | -31.04M | -22.42M | -28.73M | -13.04M | -6.77M | -11.85M | -9.35M | -4.33M | -7.5M | -10.13M | -8.61M | -10.09M | -11.97M | -13.64M | -7.9M | -10.5M | -12.26M | -8.18M | -7.56M |
| FCF Margin % | 43.05% | 177.6% | -107.77% | -466.57% | -384.03% | -1424.3% | - | -75.56% | - | -3148.6% | -309.66% | -105.47% | -190.67% | -4897.11% | 2204.01% | -387.89% | -3000.4% | -2997.63% | -4784.44% | -4694.88% | -1852.94% | -338.64% | -89.5% | -94.64% | -107.94% | -118.63% | -233.64% |
| FCF Growth % | -36.69% | 237.24% | -3.04% | -51.87% | 19.11% | -1.58% | -108.51% | 56.68% | -38.47% | 21.96% | -120.23% | -92.76% | 42.9% | -26.82% | -116.07% | 42.34% | 25.97% | -17.65% | 14.68% | 15.67% | 12.22% | -72.64% | 24.79% | 14.35% | -49.99% | -8.09% | - |
| FCF per Share | 0.33 | 0.55 | -0.41 | -0.40 | -0.27 | -0.36 | -0.44 | -0.24 | -0.61 | -0.44 | -0.57 | -0.27 | -0.17 | -0.33 | -0.27 | -0.13 | -0.26 | -0.36 | -0.30 | -0.36 | -0.43 | -0.50 | -0.30 | -0.40 | -0.47 | -0.59 | -0.54 |
| FCF Conversion (FCF/Net Income) | 0.90x | -3.49x | 1.91x | 1.01x | 0.68x | 0.95x | 1.02x | 0.59x | 0.83x | 0.63x | 1.27x | 1.00x | 0.46x | 0.80x | 0.77x | 0.59x | 1.95x | 0.80x | 0.69x | 0.76x | 0.79x | 0.89x | 0.49x | 0.74x | 0.63x | 0.46x | 0.71x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 20K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Binary clinical milestone dependence
As reported in financial statements, Compugen's cash conversion is highly erratic, with the 2022Q4 period showing an OCF/NI ratio of 7.45, indicating that reported net income significantly understates the actual cash burn required to sustain the company's ongoing clinical research and development activities.
The wide divergence between net income and operating cash flow suggests that accounting-based profitability is a poor proxy for the company's true liquidity position. Investors should monitor this gap closely, as it highlights that the firm's operational reality is defined by cash-intensive R&D rather than the accounting gains recognized from milestone-based revenue.
Based on Compugen's reported figures, the free cash flow trajectory is characterized by deep, episodic deficits, with a 2022Q4 FCF margin of -3.1% illustrating the company's reliance on external capital or non-recurring inflows to fund its persistent negative cash flow from operations.
The lack of consistent positive free cash flow suggests that the company remains in a capital-consuming phase of its lifecycle. The absence of sustained FCF generation implies that the firm's valuation is likely driven by the potential for future milestone payments rather than current operational self-sufficiency.
According to recent SEC filings, Compugen maintains a low capital intensity, with CapEx/Revenue ratios reaching 4.7% in 2022Q4, which confirms that the company's primary resource allocation is directed toward human capital and clinical trial costs rather than heavy investment in physical manufacturing or infrastructure.
The low level of capital expenditure appears to be a strategic choice, allowing the firm to preserve its cash runway for R&D. This asset-light model is appropriate for a discovery-stage biotech, though it warrants further investigation into whether this under-investment in infrastructure could limit future commercialization capabilities.
As indicated by historical financial data, Compugen's capital deployment has been marked by significant share repurchases, such as the $18.4M outflow in 2022Q4, which appears counterintuitive for a clinical-stage company that simultaneously reports negative operating cash flows and relies on milestone-based revenue for survival.
The decision to return capital to shareholders while the core business remains cash-flow negative suggests a management focus on share price support. Investors should monitor whether this deployment strategy compromises the company's ability to fund its long-term clinical pipeline without resorting to dilutive equity financing.
Quick answers to the most common questions about buying CGEN stock.
Compugen Ltd. (CGEN) generated $31.6M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Compugen Ltd. (CGEN) generated $31.3M in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Compugen Ltd. (CGEN) spent $0.3M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.