Latest Ratios: P/E Ratio -18.1x · EV/EBITDA N/A · ROE -32.1%. (2019–2025 historical series)
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Market Cap | $910M | $271M | $87M | — | — | — | — | — |
| Enterprise Value | $875M | $236M | $-3058 | — | — | — | — | — |
| P/E Ratio → | -18.07 | — | — | — | — | — | — | — |
| P/S Ratio | — | — | — | — | — | — | — | — |
| P/B Ratio | 6.72 | 1.69 | 0.41 | — | — | — | — | — |
| P/FCF | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | — | — | — | — | — | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Gross Margin | — | — | — | — | — | — | — | — |
| Operating Margin | — | — | — | — | — | — | — | — |
| Net Profit Margin | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| ROE | -32.1% | -32.1% | -46.3% | -29.7% | -30.6% | -50.3% | -98.0% | -31.8% |
| ROA | -31.1% | -31.1% | -45.1% | -28.6% | -29.4% | -48.0% | -89.8% | -30.6% |
| ROIC | -40.6% | -40.6% | -87.9% | -60.1% | -32.9% | -44.1% | -6678.2% | — |
| ROCE | -36.4% | -36.4% | -51.3% | -34.1% | -30.5% | -37.8% | -99.2% | -36.1% |
Solvency and debt-coverage ratios — lower is generally safer
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | — | — | — |
| Debt / EBITDA | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | -0.22 | -0.41 | -0.86 | -0.33 | -0.28 | -0.95 | -1.03 |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | — | — | — |
| Interest Coverage | — | — | — | — | — | — | — | — |
Net cash position: cash ($36M) exceeds total debt ($541000)
Short-term solvency ratios and asset-utilisation metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Current Ratio | 15.16 | 15.16 | 31.41 | 38.92 | 22.04 | 24.58 | 7.18 | 27.18 |
| Quick Ratio | 15.16 | 15.16 | 31.41 | 38.92 | 22.04 | 24.58 | 7.18 | 27.18 |
| Cash Ratio | 14.47 | 14.47 | 30.61 | 37.70 | 20.27 | 22.63 | 6.69 | 27.10 |
| Asset Turnover | — | — | — | — | — | — | — | — |
| Inventory Turnover | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | — | — | — | — | — | — | — |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 |
|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | — | — | — | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | — | — | — | — | — |
| Shares Outstanding | — | $68M | $48M | $27M | $26M | $12M | $12M | $12M |
Includes 30+ ratios · 7 years · Updated daily
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10-year return with dividends reinvested.
Compare growth, multiples, and margins vs sector.
Quick answers to the most common questions about buying CLYM stock.
Climb Bio, Inc.'s current P/E ratio is -18.1x. This places it at the 50th percentile of its historical range.
Climb Bio, Inc.'s return on equity (ROE) is -32.1%. The historical average is -45.5%.
Based on historical data, Climb Bio, Inc. is trading at a P/E of -18.1x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
Key Metrics
Top Statement Risk
Cash runway and single-asset risk
Liquidity Buffer Masks Tight Runway
Current ratio improved to 31.45 in 2026Q2 from 27.86 in 2026Q1, per balance sheet data, but cash of $44.1M covers only about three quarters of operating burn, suggesting limited buffer.
The current ratio of 31.45 appears robust, yet it is inflated by the absence of meaningful current liabilities beyond accrued expenses, as the company holds minimal debt and no payables. With quarterly net losses averaging $13.5M, the liquidity position translates to roughly three quarters of runway, which is tight for a Phase 2-ready biotech. Investors should monitor whether the cash balance can sustain operations through the next clinical milestone without a dilutive raise.
Minimal Debt Masks Equity Dependence
Total debt of $1.3M in 2026Q2 yields a D/E ratio of 0.01, as reported, indicating virtually no reliance on borrowed capital, but the model is entirely equity-funded.
The near-zero leverage suggests no immediate refinancing or covenant risk, but it also highlights the company's dependence on equity issuance for survival. Given the negative ROE of -7.0% in 2026Q2 and the need for capital to fund budoprutug's trials, the absence of debt may indicate limited access to credit markets for a pre-revenue biotech. The balance sheet appears adequate only if the company can secure follow-on financing before cash depletion.
Asset-Light Model with No Working Capital Cycle
Asset turnover and cash conversion cycle data are unavailable, but PP&E of $1.9M in 2026Q2 represents less than 1% of total assets, per balance sheet data, confirming an asset-light model.
The lack of inventory and receivables means the cash conversion cycle is not meaningful for a clinical-stage biotech, as the company's burn is driven by R&D expenses rather than working capital. The minimal fixed-asset base suggests that efficiency metrics like asset turnover are irrelevant, and the focus should be on cash burn per clinical milestone. The reported DPO figures in 2026Q1 and 2025Q4 are likely artifacts of trial-related accruals, not supplier leverage, and should not be interpreted as operational efficiency.
Return on Capital Decays Post-Pivot
ROIC improved from -103.8% in 2024Q2 to -6.8% in 2026Q2, per reported figures, but remains deeply negative, reflecting ongoing investment in a single unproven asset.
The dramatic improvement in ROIC from the acquisition quarter is misleading, as it reflects a larger equity base from the Tenet deal rather than operational progress. The current -6.8% ROIC indicates that the company is still burning capital without generating returns, which is typical for a pre-revenue biotech but warrants scrutiny given the tight cash runway. The negative returns are driven by R&D spending, not asset inefficiency, and will only turn positive if budoprutug achieves clinical and commercial success.
Valuation Discount Reflects Proof-of-Concept Risk
CLYM's P/B of 7.37 sits below peers like IMVT at 9.35 and RVMD at 24.71, per peer data, suggesting the market assigns a lower multiple to its unproven mAb approach.
Compared to CAR-T-focused peers like KYTX and CABA, CLYM's valuation appears to embed a discount for the lack of late-stage data and the binary risk of a single asset. The negative ROE of -7.0% is less severe than peers like IMVT at -69.6% or RVMD at -96.4%, but this is partly due to a smaller capital base rather than superior profitability. The P/B gap may narrow if budoprutug's Phase 2 data shows competitive efficacy, but until then, the discount appears justified by the clinical uncertainty.
Misapplied Metric: Current Ratio Overstates Safety
The current ratio of 31.45 in 2026Q2, per balance sheet data, is commonly misread as a strong liquidity buffer, but it obscures the true cash runway of only three quarters.
For a pre-revenue biotech, the current ratio is misleading because it compares cash against minimal current liabilities, ignoring the ongoing R&D burn that will deplete cash regardless of the ratio. A more appropriate metric is the cash runway-to-milestone ratio, which divides cash by quarterly burn to assess whether the company can reach its next clinical data readout without financing. Investors should focus on the $35.7M cash position and the $13.5M quarterly loss, which suggest a runway of roughly two to three quarters, rather than the headline current ratio.