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CRBU logoCaribou Biosciences, Inc.(CRBU)Earnings, Financials & Key Ratios

CRBU•NASDAQ
$1.88
$176M mkt cap·Price updated May 7, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutCaribou Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the development of genome-edited allogeneic cell therapies for the treatment of hematologic malignancies and solid tumors in the United States and internationally. Its lead product candidates are CB-010, an allogeneic anti-CD19 CAR-T cell therapy that is in phase 1 clinical trial to treat relapsed or refractory B cell non-Hodgkin lymphoma; and CB-011, an allogeneic anti-BCMA CAR-T cell therapy for the treatment of relapsed or refractory multiple myeloma. The company also develops CB-012, an allogeneic anti-CD371 CAR-T cell therapy for the treatment of relapsed or refractory acute myeloid leukemia; and CB-020, an allogeneic CAR-NK cell therapy for the treatment of solid tumors. It has collaboration with AbbVie Manufacturing Management Unlimited Company to develop CAR-T cell therapies. The company was incorporated in 2011 and is headquartered in Berkeley, California.Show more
  • Revenue$0-100.0%
  • EBITDA-$148M+8.8%
  • Net Income-$148M+0.7%
  • EPS (Diluted)-1.59+3.6%
  • ROE-78.97%-64.5%
  • ROIC-55.6%-35.2%
  • Debt/Equity0.22+112.8%
Technical→

CRBU Key Insights

Caribou Biosciences, Inc. (CRBU) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Trading at only 1.4x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

CRBU Price & Volume

Caribou Biosciences, Inc. (CRBU) stock price & volume — 10-year historical chart

Loading chart...

CRBU Growth Metrics

Caribou Biosciences, Inc. (CRBU) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-19%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-6.08%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-3.03%

Return on Capital

10 Years-52.61%
5 Years-41.29%
3 Years-49.36%
Last Year-68.58%

CRBU Recent Earnings

Caribou Biosciences, Inc. (CRBU) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 9/12 qtrs (75%)●Beat Revenue 9/12 qtrs (75%)
Q2 2026Latest
Mar 5, 2026
EPS
$0.28
Est $0.33
+15.2%
Revenue
$4M
Est $2M
+78.6%
Q4 2025
Nov 12, 2025
EPS
$0.30
Est $0.36
+16.7%
Revenue
$2M
Est $2M
+12.3%
Q3 2025
Aug 12, 2025
EPS
$0.35
Est $0.40
+12.5%
Revenue
$3M
Est $2M
+74.1%
Q2 2025
May 8, 2025
EPS
$0.43
Est $0.43
+0.0%
Revenue
$2M
Est $2M
+27.1%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 5, 2026
$0.28vs $0.33+15.2%
$4Mvs $2M+78.6%
Q4 2025Nov 12, 2025
$0.30vs $0.36+16.7%
$2Mvs $2M+12.3%
Q3 2025Aug 12, 2025
$0.35vs $0.40+12.5%
$3Mvs $2M+74.1%
Q2 2025May 8, 2025
$0.43vs $0.43+0.0%
$2Mvs $2M+27.1%
Based on last 12 quarters of dataView full earnings history →

CRBU Peer Comparison

Caribou Biosciences, Inc. (CRBU) competitors in Cell and Gene Therapy Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
EDIT logoEDITEditas Medicine, Inc.Direct Competitor296.54M3.03-1.68-100%-5.23%0.66
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.23B31.47-38.85120.01%-49.17%-5.89%0.24
NTLA logoNTLAIntellia Therapeutics, Inc.Direct Competitor1.62B13.71-3.6016.92%-6.1%-56.63%0.14
CRSP logoCRSPCRISPR Therapeutics AGDirect Competitor5.06B52.42-8.10-89.97%-138.57%-30.88%0.21
FATE logoFATEFate Therapeutics, Inc.Product Competitor280.32M2.43-2.11-51.24%-20.51%-65.79%0.38
ALLO logoALLOAllogene Therapeutics, Inc.Product Competitor520.77M2.27-2.61-100%-57.07%0.26
ILMN logoILMNIllumina, Inc.Supply Chain21.07B138.7125.45-0.78%19.43%32.84%0.94
TMO logoTMOThermo Fisher Scientific Inc.Supply Chain176.36B474.5626.753.91%15.18%13.23%0.76

Compare CRBU vs Peers

Caribou Biosciences, Inc. (CRBU) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs EDIT

Most directly comparable listed peer for CRBU.

Scale Benchmark

vs TMO

Larger-name benchmark to compare CRBU against a more recognizable public peer.

Peer Set

Compare Top 5

vs EDIT, BEAM, NTLA, CRSP

CRBU Income Statement

Caribou Biosciences, Inc. (CRBU) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue5.79M12.36M9.6M13.85M34.48M9.99M09.29M
Revenue Growth %-113.56%-22.35%44.31%148.91%-71.01%-100%-19%
Cost of Goods Sold034.42M984K3.64M3.52M3.93M030.5M
COGS % of Revenue-278.5%10.25%26.29%10.22%39.29%--
Gross Profit
5.79M▲ 0%
-22.06M▼ 481.2%
8.61M▲ 139.0%
10.21M▲ 18.5%
30.95M▲ 203.2%
6.07M▼ 80.4%
0▼ 100.0%
-21.2M▲ 0%
Gross Margin %100%-178.5%89.75%73.71%89.78%60.71%--228.08%
Gross Profit Growth %--481.2%139.04%18.53%203.15%-80.4%-100%-
Operating Expenses40.09M14.06M75.59M116.61M147.01M172.68M159.5M137.57M
OpEx % of Revenue692.69%113.74%787.59%841.88%426.4%1727.87%--
Selling, General & Admin16.46M14.06M23.34M38.02M38.46M46.46M37.91M39.19M
SG&A % of Revenue284.35%113.74%243.15%274.49%111.56%464.85%--
Research & Development23.64M34.42M52.26M82.23M112.08M130.15M109.44M116.09M
R&D % of Revenue408.34%278.5%544.44%593.68%325.07%1302.31%--
Other Operating Expenses0-34.42M0-3.64M-3.52M-3.93M12.15M0
Operating Income
-34.3M▲ 0%
-36.12M▼ 5.3%
-66.98M▼ 85.4%
-106.4M▼ 58.9%
-116.06M▼ 9.1%
-166.62M▼ 43.6%
-148.34M▲ 11.0%
-158.77M▲ 0%
Operating Margin %-592.69%-292.24%-697.84%-768.17%-336.63%-1667.16%--1708.08%
Operating Income Growth %--5.3%-85.41%-58.85%-9.08%-43.56%10.97%-
EBITDA-33.55M-35.22M-66M-102.76M-112.53M-162.69M-148.34M-154.62M
EBITDA Margin %-579.72%-284.96%-687.59%-741.88%-326.4%-1627.87%--1663.46%
EBITDA Growth %--4.98%-87.36%-55.71%-9.51%-44.57%8.82%4.38%
D&A (Non-Cash Add-back)751K900K984K3.64M3.52M3.93M04.15M
EBIT-30.96M-36.11M-66.59M-99.35M-116.06M-166.62M0-144.16M
Net Interest Income1.04M216K140K4.6M10.7M000
Interest Income1.05M236K148K4.6M10.7M000
Interest Expense4K20K8K00000
Other Income/Expense3.34M-3K377K7.05M14.18M17.5M-331K1.63M
Pretax Income
-30.97M▲ 0%
-36.13M▼ 16.7%
-66.6M▼ 84.4%
-99.35M▼ 49.2%
-101.88M▼ 2.5%
-149.11M▼ 46.4%
-148.68M▲ 0.3%
-157.14M▲ 0%
Pretax Margin %-535.04%-292.27%-693.92%-717.28%-295.49%-1492.04%--1690.54%
Income Tax-7.54M-1.82M321K70K193K-9K-550K-9K
Effective Tax Rate %24.34%5.04%-0.48%-0.07%-0.19%0.01%0.37%0.01%
Net Income
-23.43M▲ 0%
-34.31M▼ 46.4%
-66.92M▼ 95.1%
-99.42M▼ 48.6%
-102.07M▼ 2.7%
-149.1M▼ 46.1%
-148.13M▲ 0.7%
-157.13M▲ 0%
Net Margin %-404.82%-277.55%-697.26%-717.79%-296.05%-1491.95%--1690.45%
Net Income Growth %--46.42%-95.07%-48.56%-2.66%-46.08%0.66%-6.08%
Net Income (Continuing)-23.43M-34.31M-66.92M-99.42M-102.07M-149.1M-148.13M-157.13M
Discontinued Operations00000000
Minority Interest00000000
EPS (Diluted)
-0.85▲ 0%
-1.24▼ 45.9%
-1.11▲ 10.5%
-1.64▼ 47.7%
-1.38▲ 15.9%
-1.65▼ 19.6%
-1.59▲ 3.6%
-1.68▲ 0%
EPS Growth %--45.88%10.48%-47.75%15.85%-19.57%3.64%-3.03%
EPS (Basic)-0.85-1.24-1.11-1.64-1.38-1.65-1.59-
Diluted Shares Outstanding27.66M27.66M60.26M60.8M73.81M90.32M93.39M93.29M
Basic Shares Outstanding27.66M27.66M60.26M60.8M73.81M90.32M93.39M93.29M
Dividend Payout Ratio--------

CRBU Balance Sheet

Caribou Biosciences, Inc. (CRBU) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets57.01M24.31M391.19M260.25M338.84M219.38M145.23M155.51M
Cash & Short-Term Investments49.47M15.95M375.83M247.66M328.83M209.54M139.34M147.26M
Cash Only41.07M15.95M240.42M58.34M51.16M16.29M12.36M11.14M
Short-Term Investments8.4M0135.41M189.32M277.67M193.24M126.98M136.12M
Accounts Receivable3.98M5.16M8.12M4.66M3.86M3.25M1.97M2.07M
Days Sales Outstanding251.11152.37308.95122.9140.85118.73-106.43
Inventory00000000
Days Inventory Outstanding--------
Other Current Assets373K423K671K1.12M1.22M1.78M3.92M6.18M
Total Non-Current Assets4.92M11.74M51.16M113.52M93.37M93.94M30.14M39.48M
Property, Plant & Equipment4.33M3.5M4.89M34.91M40.45M39.29M24.43M23.6M
Fixed Asset Turnover1.34x3.53x1.96x0.40x0.85x0.25x-0.30x
Goodwill00000000
Intangible Assets00000000
Long-Term Investments07.63M45.3M77.07M51.33M49.13M062.65M
Other Non-Current Assets593K612K975K1.54M1.59M5.52M5.71M29.92M
Total Assets
61.93M▲ 0%
36.05M▼ 41.8%
442.36M▲ 1127.2%
373.76M▼ 15.5%
432.21M▲ 15.6%
313.31M▼ 27.5%
175.37M▼ 44.0%
194.98M▲ 0%
Asset Turnover0.09x0.34x0.02x0.04x0.08x0.03x-0.04x
Asset Growth %--41.8%1127.2%-15.51%15.64%-27.51%-44.03%-144.38%
Total Current Liabilities10.08M12.39M25.83M28.13M28.3M30.65M25.41M28.06M
Accounts Payable2.54M2.6M3.99M1.15M3.12M2.48M5.78M3.8M
Days Payables Outstanding-27.581.48K114.88323.06230.13-40.08
Short-Term Debt532K654K259K0001.2M2.69M
Deferred Revenue (Current)717K161K8.7M9.94M2.85M3.13M1.9M11M
Other Current Liabilities496K629K4.75M7.12M10.62M10.22M22.32M19.35M
Current Ratio5.66x1.96x15.15x9.25x11.97x7.16x5.71x5.71x
Quick Ratio5.66x1.96x15.15x9.25x11.97x7.16x5.71x5.71x
Cash Conversion Cycle-------66.34
Total Non-Current Liabilities44.39M47.09M28.7M44.77M35.51M29.71M27.78M25.08M
Long-Term Debt0924K000026.03M0
Capital Lease Obligations00026.78M25.91M25.06M095.72M
Deferred Tax Liabilities650K155K476K381K557K548K02.19M
Other Non-Current Liabilities42.76M45.08M6.19M1.65M2.94M785K1.75M1.24M
Total Liabilities54.47M59.48M54.53M72.89M63.81M60.36M53.19M53.14M
Total Debt532K1.58M259K27.75M27.11M26.49M27.23M25.46M
Net Debt-40.54M-14.38M-240.42M-30.59M-24.05M10.19M14.87M14.32M
Debt / Equity0.07x-0.00x0.09x0.07x0.10x0.22x0.22x
Debt / EBITDA--------0.16x
Net Debt / EBITDA--------0.09x
Interest Coverage-8576.25x-1806.20x-8372.38x-----
Total Equity
7.46M▲ 0%
-23.44M▼ 414.0%
387.82M▲ 1754.8%
300.87M▼ 22.4%
368.4M▲ 22.4%
252.95M▼ 31.3%
122.17M▼ 51.7%
141.84M▲ 0%
Equity Growth %--414.04%1754.76%-22.42%22.44%-31.34%-51.7%-164.11%
Book Value per Share0.27-0.856.444.954.992.801.311.52
Total Shareholders' Equity7.46M-23.44M387.82M300.87M368.4M252.95M122.17M141.84M
Common Stock1K1K6K6K8K9K9K9K
Retained Earnings3.44M-30.87M-97.79M-197.22M-299.29M-448.39M-596.51M-570.03M
Treasury Stock00000000
Accumulated OCI00-135K-1.52M30K255K103K93K
Minority Interest00000000

CRBU Cash Flow Statement

Caribou Biosciences, Inc. (CRBU) cash flow — operating, investing & free cash flow history

Line itemDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations-32.01M-33.22M-32.52M-90.97M-93.29M-138.2M-110.99M-110.99M
Operating CF Margin %-552.97%-268.71%-338.81%-656.75%-270.59%-1382.83%--
Operating CF Growth %--3.78%2.1%-179.73%-2.56%-48.14%19.69%-27.72%
Net Income-23.43M-34.31M-66.92M-99.42M-102.07M-149.1M-148.13M-157.13M
Depreciation & Amortization751K900K984K3.64M3.52M3.93M3.65M4.15M
Stock-Based Compensation1.23M1M3.45M013.75M16.71M12.68M13.85M
Deferred Taxes000-95K00-548K0
Other Non-Cash Items-2.29M-986K904K9.02M-1.18M-4.61M21.36M20.14M
Working Capital Changes-8.27M177K29.07M-4.11M-7.32M-5.11M0-6.65M
Change in Receivables-1.09M-1.18M-2.96M3.46M805K608K196K-266K
Change in Inventory00000000
Change in Payables1.18M43K1.14M-2.72M1.82M-354K3.25M1.11M
Cash from Investing27.23M6.36M-176.4M-93.25M-68.18M86.61M102.24M100.2M
Capital Expenditures-884K-317K-2.12M-6.45M-11.61M-4.88M-1.36M-468K
CapEx % of Revenue15.27%2.56%22.1%46.6%33.68%48.83%--
Acquisitions00000000
Investments--------
Other Investing0-988K-1M-600K0-1.61M1.14M-1.61M
Cash from Financing172K1.74M433.43M2.13M154.3M16.72M4.82M4.61M
Debt Issued (Net)-45K1.47M1.03M00000
Equity Issued (Net)217K270K1000K1000K1000K1000K02.21M
Dividends Paid00000000
Share Repurchases00000000
Other Financing002.55M01.58M1.53M4.82M451K
Net Change in Cash
-4.6M▲ 0%
-25.12M▼ 445.9%
224.51M▲ 993.9%
-182.08M▼ 181.1%
-7.18M▲ 96.1%
-34.87M▼ 385.9%
-3.93M▲ 88.7%
-20.83M▲ 0%
Free Cash Flow
-32.89M▲ 0%
-34.53M▼ 5.0%
-35.64M▼ 3.2%
-97.42M▼ 173.3%
-104.9M▼ 7.7%
-144.71M▼ 37.9%
-112.35M▲ 22.4%
-127.73M▲ 0%
FCF Margin %-568.24%-279.35%-371.33%-703.34%-304.27%-1447.92%--1374.19%
FCF Growth %--4.99%-3.21%-173.34%-7.68%-37.94%22.36%3.51%
FCF per Share-1.19-1.25-0.59-1.60-1.42-1.60-1.20-1.20
FCF Conversion (FCF/Net Income)1.37x0.97x0.49x0.91x0.91x0.93x0.75x0.81x
Interest Paid00000000
Taxes Paid1.81M21K11K0170K000

CRBU Key Ratios

Caribou Biosciences, Inc. (CRBU) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric202020212022202320242025TTM
Return on Equity (ROE)--36.73%-28.87%-30.5%-47.99%-78.97%-80.77%
Return on Invested Capital (ROIC)--91.46%-38.19%-28.32%-41.14%-55.6%-55.6%
Gross Margin-178.5%89.75%73.71%89.78%60.71%--228.08%
Net Margin-277.55%-697.26%-717.79%-296.05%-1491.95%--1690.45%
Debt / Equity-0.00x0.09x0.07x0.10x0.22x0.22x
Interest Coverage-1806.20x-8372.38x-----
FCF Conversion0.97x0.49x0.91x0.91x0.93x0.75x0.81x
Revenue Growth113.56%-22.35%44.31%148.91%-71.01%-100%-19%

CRBU SEC Filings & Documents

Caribou Biosciences, Inc. (CRBU) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 31, 2026·SEC

Material company update

Mar 5, 2026·SEC

Material company update

Nov 12, 2025·SEC

10-K Annual Reports

3
FY 2026

Mar 5, 2026·SEC

FY 2025

Mar 10, 2025·SEC

FY 2024

Mar 11, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

FY 2025

May 8, 2025·SEC

CRBU Frequently Asked Questions

Caribou Biosciences, Inc. (CRBU) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Caribou Biosciences, Inc. (CRBU) reported $9.3M in revenue for fiscal year 2025. This represents a 61% increase from $5.8M in 2019.

Caribou Biosciences, Inc. (CRBU) saw revenue decline by 100.0% over the past year.

Caribou Biosciences, Inc. (CRBU) reported a net loss of $157.1M for fiscal year 2025.

Dividend & Returns

Caribou Biosciences, Inc. (CRBU) has a return on equity (ROE) of -79.0%. Negative ROE indicates the company is unprofitable.

Caribou Biosciences, Inc. (CRBU) had negative free cash flow of $127.7M in fiscal year 2025, likely due to heavy capital investments.

Explore More CRBU

Caribou Biosciences, Inc. (CRBU) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

→

Revenue History

Sales growth patterns & revenue breakdown

→

Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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