Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in CRBU held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | PFIZER INC | 4.7M | $8.3M | 0.0% | 4.729% | 3.50% |
| 2 | VANGUARD CAPITAL MANAGEMENT LLC | 3.8M | $7.2M | β | 3.798% | 0.00% |
| 3 | RENAISSANCE TECHNOLOGIES LLC | 2.6M | $4.9M | +58.0% | 2.612% | 0.01% |
| 4 | Kynam Capital Management, LP | 2.5M | $4.8M | 0.0% | 2.524% | 0.30% |
| 5 | BlackRock, Inc. | 2.1M | $4.1M | +0.1% | 2.161% | 0.00% |
| 6 | TWO SIGMA INVESTMENTS, LP | 1.8M | $3.3M | +72.5% | 1.774% | 0.00% |
| 7 | BANK OF AMERICA CORP /DE/ | 1.3M | $2.5M | +30.6% | 1.308% | 0.00% |
| 8 | abrdn plc | 1.2M | $2.3M | -12.7% | 1.223% | 0.00% |
| 9 | MARSHALL WACE, LLP | 1.2M | $2.3M | +36.8% | 1.216% | 0.00% |
| 10 | MILLENNIUM MANAGEMENT LLC | 1.1M | $2.0M | +40.1% | 1.083% | 0.00% |
| 11 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.0M | $2.0M | -3.8% | 1.056% | 0.00% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 1.0M | $1.9M | +4.2% | 1.026% | 0.00% |
| 13 | PFM Health Sciences, LP | 958K | $1.8M | 0.0% | 0.966% | 0.18% |
| 14 | MACKENZIE FINANCIAL CORP | 943K | $1.8M | β | 0.951% | 0.00% |
| 15 | FMR LLC | 724K | $1.4M | -0.3% | 0.730% | 0.00% |
| 16 | DIMENSIONAL FUND ADVISORS LP | 673K | $1.3M | -33.1% | 0.679% | 0.00% |
| 17 | MAVERICK CAPITAL LTD | 653K | $1.2M | 0.0% | 0.658% | 0.01% |
| 18 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 560K | $1.1M | +0.7% | 0.564% | 0.00% |
| 19 | VANGUARD FIDUCIARY TRUST CO | 520K | $988K | β | 0.524% | 0.00% |
| 20 | 72 Investment Holdings, LLC | 474K | $901K | 0.0% | 0.478% | 1.82% |
| 21 | STATE STREET CORP | 423K | $804K | 0.0% | 0.427% | 0.00% |
| 22 | GOLDMAN SACHS GROUP INC | 377K | $716K | -23.0% | 0.380% | 0.00% |
| 23 | Green Alpha Advisors, LLC | 374K | $710K | -0.4% | 0.377% | 0.70% |
| 24 | JACOBS LEVY EQUITY MANAGEMENT, INC | 359K | $682K | -56.5% | 0.362% | 0.00% |
| 25 | XTX Topco Ltd | 323K | $615K | -21.8% | 0.326% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in CRBU β a direct measure of their conviction.
Filings activity in CRBU during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new CRBU position in Q1 2026
Institutions that fully closed their CRBU position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 131 | +7.4% | 42.97% | +6.63 pp | $68M | +18% |
| Q4 2025 | 122 | +5.2% | 36.34% | 17.43 pp | $57M | 32% |
| Q3 2025 | 116 | 9.4% | 53.77% | +22.34 pp | $85M | +71% |
| Q2 2025 | 128 | 2.3% | 31.43% | +3.18 pp | $50M | +11% |
| Q1 2025 | 131 | 2.2% | 28.25% | 29.73 pp | $45M | 51% |
| Q4 2024 | 134 | +4.7% | 57.98% | 6.37 pp | $92M | 9.9% |
| Q3 2024 | 128 | 6.6% | 64.35% | +9.75 pp | $102M | +18% |
| Q2 2024 | 137 | β | 54.60% | β | $86M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CRBU stock.
Based on Q1 2026 13F filings, institutional ownership of Caribou Biosciences, Inc. stands at 43.0%, held across 131 reporting institutions.
PFIZER INC is the largest reported institutional holder of CRBU, with approximately 4,690,431 shares worth $0.01B as of Q1 2026.
Yes β 4 widely-followed marquee investors appear among the top 25 institutional holders of CRBU, including RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP, MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for CRBU is 74 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
28 institutions opened new positions in CRBU during Q1 2026, while 19 fully exited. 85 added to existing positions and 18 trimmed.
CRBU institutional ownership rose by 6.63 percentage points quarter-over-quarter, with a net change of +9 holders.
The top 10 institutions account for 61.4% of all reported 13F value in CRBU, and the top 25 account for 87.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Caribou Biosciences, Inc. (CRBU) Institutional Ownership