Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in CYCN held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | GEODE CAPITAL MANAGEMENT, LLC | 85K | $130K | +95.3% | 1.953% | 0.00% |
| 2 | CITADEL ADVISORS LLC | 18K | $28K | β | 0.422% | 0.00% |
| 3 | BlackRock, Inc. | 17K | $26K | 0.0% | 0.388% | 0.00% |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 16K | $25K | β | 0.373% | 0.00% |
| 5 | Kovack Advisors, Inc. | 10K | $16K | β | 0.231% | 0.00% |
| 6 | VANGUARD FIDUCIARY TRUST CO | 7K | $11K | β | 0.170% | 0.00% |
| 7 | FMR LLC | 5K | $7K | 0.0% | 0.110% | 0.00% |
| 8 | UBS Group AG | 3K | $5K | +801.9% | 0.078% | 0.00% |
| 9 | GROUP ONE TRADING, L.P. | 192 | $295 | 0.0% | 0.004% | 0.00% |
| 10 | ADVISOR GROUP HOLDINGS, INC. | 130 | $201 | 0.0% | 0.003% | 0.00% |
| 11 | MAI Capital Management | 100 | $155 | 0.0% | 0.002% | 0.00% |
| 12 | Activest Wealth Management | 100 | $155 | 0.0% | 0.002% | 0.00% |
| 13 | CITIGROUP INC | 89 | $137 | -98.9% | 0.002% | 0.00% |
| 14 | WHI TRUST Co LLC | 72 | $112 | 0.0% | 0.002% | 0.00% |
| 15 | BNP PARIBAS ARBITRAGE, SA | 5 | $8 | 0.0% | 0.000% | 0.00% |
| 16 | Caitong International Asset Management Co., Ltd | 4 | $6 | β | 0.000% | 0.00% |
| 17 | MORGAN STANLEY | 1 | $2 | 0.0% | 0.000% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in CYCN β a direct measure of their conviction.
Filings activity in CYCN during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 17 | 11% | 1.77% | 0.90 pp | $0M | 34% |
| Q4 2025 | 19 | +19% | 2.67% | 0.85 pp | $0M | 24% |
| Q3 2025 | 16 | 11% | 3.52% | 3.98 pp | $0M | 53% |
| Q2 2025 | 18 | 5.3% | 7.50% | +0.88 pp | $1M | +13% |
| Q1 2025 | 19 | +0.0% | 6.62% | 2.12 pp | $1M | 24% |
| Q4 2024 | 19 | +19% | 8.74% | 10.42 pp | $1M | 54% |
| Q3 2024 | 16 | 11% | 19.16% | +2.02 pp | $3M | +12% |
| Q2 2024 | 18 | β | 17.14% | β | $2M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying CYCN stock.
Based on Q1 2026 13F filings, institutional ownership of Cyclerion Therapeutics, Inc. stands at 1.8%, held across 17 reporting institutions.
GEODE CAPITAL MANAGEMENT, LLC is the largest reported institutional holder of CYCN, with approximately 84,550 shares worth $0.00B as of Q1 2026.
Yes β 1 widely-followed marquee investor appear among the top 25 institutional holders of CYCN, including CITADEL ADVISORS LLC.
Our composite Smart Money Score for CYCN is 38 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
5 institutions opened new positions in CYCN during Q1 2026, while 7 fully exited. 10 added to existing positions and 1 trimmed.
CYCN institutional ownership fell by 0.90 percentage points quarter-over-quarter, with a net change of -2 holders.
The top 10 institutions account for 99.8% of all reported 13F value in CYCN, and the top 25 account for 100.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Cyclerion Therapeutics, Inc. (CYCN) Institutional Ownership