Last 37 quarters of trend data
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -10.41 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 5.00 | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/B Ratio | 8.94 | 5.67 | 7.37 | 3.60 | 7.75 | 2.99 | 2.29 | 2.42 | 1.74 | 2.57 | 2.29 | 1.89 | 1.30 | 1.30 | 0.93 | 0.55 | 0.67 | 2.18 | 3.43 | 3.83 | 5.90 |
| — | +89.7% | +222.5% | +48.8% | +345.3% | +16.4% | -0.3% | +28.2% | +34.4% | +97.5% | +147.8% | +240.8% | +94.0% | -40.3% | -73.0% | -85.5% | -88.7% | -72.9% | -40.9% | -75.5% | -31.0% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Operating Margin | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Net Margin | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -64.1% | -26.6% | -25.2% | -21.8% | -42.6% | -20.9% | -10.1% | -13.8% | -5.9% | -2.9% | -27.7% | -27.4% | -17.7% | -24.7% | -17.6% | -3.2% | -11.9% | -13.0% | -12.8% | -10.6% | -10.0% |
| — | -26.8% | -150.8% | -57.9% | -622.2% | -612.1% | +63.7% | +49.7% | +66.8% | +88.1% | -57.2% | -751.2% | -49.7% | -90.0% | -37.9% | +69.6% | -18.0% | +47.8% | -22.5% | +59.6% | +72.6% | |
| ROA | -49.5% | -21.0% | -18.3% | -14.9% | -26.8% | -15.8% | -8.1% | -11.2% | -4.7% | -2.2% | -19.7% | -17.9% | -12.6% | -19.6% | -15.2% | -2.8% | -10.5% | -12.0% | -11.8% | -9.8% | -9.2% |
| — | -32.7% | -126.6% | -33.4% | -475.7% | -634.6% | +59.0% | +37.7% | +63.2% | +89.0% | -29.5% | -541.9% | -20.8% | -63.6% | -29.4% | +71.6% | -13.3% | +47.8% | -20.9% | +58.7% | +71.5% | |
| ROIC | -389.5% | -35.6% | -97.8% | -31.6% | -19.9% | -17.3% | -31.8% | — | — | — | — | — | — | — | -317.6% | -260.9% | -141.7% | -72.3% | -80.6% | -68.9% | -65.5% |
| — | -106.2% | -207.3% | — | — | — | — | — | — | — | — | — | — | — | -294.2% | -278.9% | -116.2% | +50.0% | +9.3% | — | +70.4% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | 0.04 | — | — | 0.31 | 0.22 | 0.10 | 0.09 | 0.09 | 0.12 | 0.07 | 0.18 | 0.15 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | — | — | — |
| — | -82.1% | — | — | +233.5% | +85.1% | +36.7% | -49.9% | -36.7% | +16853.0% | +13011.6% | +37809.9% | +31626.0% | +26.0% | — | — | — | — | — | — | — | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 6.29 | 6.95 | 4.69 | 6.29 | 3.30 | 4.98 | 7.27 | 7.25 | 9.00 | 5.92 | 3.91 | 3.22 | 3.85 | 3.41 | 5.50 | 8.16 | 6.01 | 13.86 | 11.67 | 13.18 | 25.32 |
| — | +39.4% | -35.5% | -13.3% | -63.3% | -15.8% | +85.8% | +125.0% | +133.5% | +73.5% | -28.8% | -60.5% | -35.9% | -75.4% | -52.9% | -38.1% | -76.3% | -6.3% | -53.6% | -51.4% | +442.6% | |
| Quick Ratio | 6.29 | 6.95 | 4.69 | 6.29 | 3.30 | 4.98 | 7.27 | 7.25 | 9.00 | 5.92 | 3.91 | 3.22 | 3.85 | 3.41 | 5.50 | 8.16 | 6.01 | 13.86 | 11.67 | 13.18 | 25.32 |
| — | +39.4% | -35.5% | -13.3% | -63.3% | -15.8% | +85.8% | +125.0% | +133.5% | +73.5% | -28.8% | -60.5% | -35.9% | -75.4% | -52.9% | -38.1% | -76.3% | -6.3% | -53.6% | -51.4% | +442.6% | |
| Interest Coverage | -32.53 | -127.94 | -60.93 | -4.20 | -51.80 | -17.28 | -37.78 | -51.96 | -17.82 | -11.56 | -124.35 | — | — | -377.31 | -325.51 | — | — | — | -685.37 | -48.91 | -269.17 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 37 years · Updated daily
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Definium Therapeutics, Inc.'s current P/E is -10.4x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Definium Therapeutics, Inc.'s business trajectory between earnings reports.