Denali Therapeutics Inc. (DNLI) Stock Price History
Historical prices from 2017 to 2026
- 1M
- +4.1%
- 3M
- -18.8%
- YTD
- +23.4%
- 1Y
- +39.3%
- 3Y
- -1.1%
- 5Y
- -18.0%
Loading 10-year price history...
DNLI Historical Performance
DNLI Annual Returns
Year-by-year price performance · 2017–2026
- 2017 annual price return
- -27.1%
- 2018 annual price return
- +28.1%
- 2019 annual price return
- -9.9%
- 2020 annual price return
- +411.0%
- 2021 annual price return
- -37.1%
- 2022 annual price return
- -41.2%
- 2023 annual price return
- -22.3%
- 2024 annual price return
- -4.7%
- 2025 annual price return
- -20.8%
- 2026 annual price return
- +19.5%
DNLI Stock Price Trajectory (2017–2026)
As of November 9, 2026, Denali Therapeutics Inc. (DNLI) trades at $20.07, representing a +39.3% return over the past year. The stock has delivered a -62.9% total return over five years (-18.0% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $93.94 on December 22, 2020. From this peak, DNLI has corrected -78.6%, currently trading 6% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers PRAX (+61.1% 1Y), ARVN (-35.9% 1Y), and RCUS (-6.5% 1Y), DNLI has underperformed the peer group average. Compare DNLI vs PRAX →
DNLI Historical Price Data · from 2017
Rows 1–50 of 2,240| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-11-06 | 19.97 | 20.36 | 19.78 | 20.07 | 1.59M | +1.77% |
| 2026-11-05 | 20.96 | 21.08 | 19.65 | 19.72 | 2.25M | -5.92% |
| 2026-11-04 | 21.23 | 22.19 | 19.75 | 20.96 | 4.90M | +7.76% |
| 2026-11-03 | 19.21 | 19.52 | 18.98 | 19.45 | 2.43M | +3.13% |
| 2026-11-02 | 19.11 | 19.20 | 18.32 | 18.86 | 1.24M | -0.42% |
| 2026-10-30 | 19.25 | 19.64 | 18.64 | 18.94 | 1.31M | -1.97% |
| 2026-10-29 | 19.35 | 19.78 | 19.14 | 19.32 | 1.45M | +0.16% |
| 2026-10-28 | 18.92 | 19.29 | 18.84 | 19.29 | 1.59M | +0.36% |
| 2026-10-27 | 18.48 | 19.32 | 18.40 | 19.22 | 1.48M | +3.00% |
| 2026-10-26 | 18.50 | 18.67 | 18.35 | 18.66 | 726K | +1.36% |
| 2026-10-23 | 18.49 | 18.50 | 18.01 | 18.41 | 1.01M | -1.34% |
| 2026-10-22 | 18.53 | 18.94 | 18.44 | 18.66 | 817K | -0.11% |
| 2026-10-21 | 18.93 | 19.13 | 18.58 | 18.68 | 1.43M | -1.32% |
| 2026-10-20 | 18.10 | 19.35 | 17.95 | 18.93 | 1.82M | +4.93% |
| 2026-10-19 | 17.61 | 18.36 | 17.33 | 18.04 | 2.69M | +2.44% |
| 2026-10-16 | 18.37 | 18.37 | 17.37 | 17.61 | 2.30M | -3.98% |
| 2026-10-15 | 18.04 | 18.53 | 18.01 | 18.34 | 1.57M | +2.63% |
| 2026-10-14 | 18.30 | 18.36 | 17.53 | 17.87 | 2.70M | -2.88% |
| 2026-10-13 | 18.82 | 19.20 | 18.15 | 18.40 | 1.94M | -2.90% |
| 2026-10-12 | 19.33 | 19.62 | 18.90 | 18.95 | 1.23M | -2.57% |
| 2026-10-09 | 18.46 | 19.52 | 18.46 | 19.45 | 1.34M | +4.18% |
| 2026-10-08 | 19.00 | 19.04 | 18.30 | 18.67 | 2.37M | -2.56% |
| 2026-10-07 | 18.95 | 19.43 | 18.89 | 19.16 | 1.31M | -0.62% |
| 2026-10-06 | 19.93 | 19.97 | 19.02 | 19.28 | 3.67M | -3.16% |
| 2026-10-05 | 20.09 | 20.09 | 19.54 | 19.91 | 1.72M | -0.45% |
| 2026-10-02 | 20.85 | 20.85 | 19.93 | 20.00 | 1.63M | -2.58% |
| 2026-10-01 | 20.55 | 20.85 | 20.40 | 20.53 | 1.94M | -0.68% |
| 2026-09-30 | 20.95 | 21.09 | 20.51 | 20.67 | 2.26M | -0.67% |
| 2026-09-29 | 20.88 | 21.01 | 20.41 | 20.81 | 1.39M | -0.81% |
| 2026-09-28 | 20.05 | 21.26 | 19.93 | 20.98 | 2.56M | +2.89% |
| 2026-09-25 | 20.46 | 20.60 | 19.96 | 20.39 | 1.26M | -0.39% |
| 2026-09-24 | 20.40 | 20.64 | 19.73 | 20.47 | 2.27M | +0.05% |
| 2026-09-23 | 21.50 | 21.51 | 20.33 | 20.46 | 1.91M | -5.28% |
| 2026-09-22 | 20.76 | 21.79 | 20.47 | 21.60 | 2.34M | +5.52% |
| 2026-09-21 | 19.99 | 20.55 | 19.40 | 20.47 | 2.39M | +3.80% |
| 2026-09-18 | 20.07 | 20.16 | 19.56 | 19.72 | 2.96M | -2.04% |
| 2026-09-17 | 20.57 | 20.65 | 19.90 | 20.13 | 1.42M | +0.35% |
| 2026-09-16 | 20.40 | 20.51 | 19.87 | 20.06 | 1.86M | -1.57% |
| 2026-09-15 | 21.01 | 21.10 | 20.27 | 20.38 | 1.84M | -3.96% |
| 2026-09-14 | 21.09 | 21.58 | 20.96 | 21.22 | 1.07M | +0.62% |
| 2026-09-11 | 21.65 | 21.79 | 21.06 | 21.09 | 1.24M | -1.45% |
| 2026-09-10 | 21.24 | 21.58 | 21.09 | 21.40 | 939K | -0.79% |
| 2026-09-09 | 21.69 | 22.06 | 21.34 | 21.57 | 2.09M | -2.31% |
| 2026-09-08 | 21.79 | 22.25 | 21.66 | 22.08 | 1.65M | -0.90% |
| 2026-09-04 | 22.32 | 22.48 | 22.15 | 22.28 | 800K | -2.28% |
| 2026-09-03 | 23.00 | 23.03 | 22.35 | 22.80 | 1.73M | -0.22% |
| 2026-09-02 | 23.33 | 23.86 | 22.53 | 22.85 | 1.77M | -1.80% |
| 2026-09-01 | 23.44 | 23.75 | 23.06 | 23.27 | 1.43M | -2.06% |
| 2026-08-31 | 23.72 | 24.01 | 23.41 | 23.76 | 986K | -1.00% |
| 2026-08-28 | 24.42 | 24.62 | 23.92 | 24.00 | 808K | -2.72% |
DNLI Chart Terminal
Live VCP patterns, Cup & Handle overlays, support/resistance, and AI trade plans.
Live Breakouts Feed
High-probability breakout stocks crossing their pivot across 5 pattern engines.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
DNLI — Frequently Asked Questions
Quick answers to the most common questions about buying DNLI stock.
How has DNLI stock performed recently?
DNLI returned +39.3% over the past year, beating its 5-year annualized CAGR of -18.0%. The stock trades below its 200-day moving average, confirming the uptrend.
What is DNLI's all-time high price?
Denali Therapeutics Inc. reached $93.94 on 2020-12-22. The 52-week high is $27.30. Current 1-year return of +39.3% places the stock closer to historical peaks.
Where can I download DNLI historical price data?
This page provides DNLI daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2017-2026, downloadable in CSV format.