Denali Therapeutics Inc. (DNLI) Stock Price History
Historical prices from 2017 to 2026
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DNLI Historical Performance
Short-Term Returns
DNLI Stock Price Trajectory (2017–2026)
As of May 8, 2026, Denali Therapeutics Inc. (DNLI) trades at $19.71, representing a +37.6% return over the past year. The stock has delivered a -63.7% total return over five years (-18.3% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $93.94 on December 22, 2020. From this peak, DNLI has corrected -79.0%, currently trading 12% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers PRAX (+775.0% 1Y), ARVN (+52.8% 1Y), and RCUS (+209.6% 1Y), DNLI has underperformed the peer group average. Compare DNLI vs PRAX →
DNLI Historical Price Data (2025–2026)
Showing 30 of 2,114 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-07 | 20.25 | 20.41 | 19.19 | 19.71 | 1.21M | -3.38% |
| 2026-05-06 | 19.20 | 20.49 | 18.91 | 20.40 | 2.18M | +7.82% |
| 2026-05-05 | 19.15 | 19.40 | 18.33 | 18.92 | 810K | +1.34% |
| 2026-05-04 | 18.14 | 19.14 | 18.10 | 18.67 | 2.41M | +2.02% |
| 2026-05-01 | 18.70 | 18.81 | 18.23 | 18.30 | 1.42M | -2.24% |
| 2026-04-30 | 18.73 | 18.92 | 18.35 | 18.72 | 2.44M | +0.65% |
| 2026-04-29 | 19.60 | 20.17 | 18.23 | 18.60 | 2.95M | -7.28% |
| 2026-04-28 | 19.97 | 20.43 | 19.84 | 20.06 | 1000K | +0.60% |
| 2026-04-27 | 19.76 | 20.36 | 19.76 | 19.94 | 968K | +0.35% |
| 2026-04-24 | 20.05 | 20.05 | 19.27 | 19.87 | 1.00M | +2.16% |
| 2026-04-23 | 20.35 | 20.36 | 19.20 | 19.45 | 1.22M | -3.95% |
| 2026-04-22 | 20.28 | 20.57 | 20.00 | 20.25 | 1.37M | +0.60% |
| 2026-04-21 | 20.50 | 20.73 | 19.94 | 20.13 | 994K | -2.00% |
| 2026-04-20 | 20.27 | 20.88 | 20.09 | 20.54 | 691K | -0.15% |
| 2026-04-17 | 21.23 | 21.37 | 20.55 | 20.57 | 1.44M | -0.68% |
| 2026-04-16 | 21.63 | 21.80 | 20.64 | 20.71 | 1.31M | -4.47% |
| 2026-04-15 | 20.24 | 21.71 | 20.20 | 21.68 | 1.85M | +7.54% |
| 2026-04-14 | 19.59 | 20.29 | 19.43 | 20.16 | 780K | +3.81% |
| 2026-04-13 | 19.45 | 19.91 | 19.02 | 19.42 | 1.08M | +0.99% |
| 2026-04-10 | 19.41 | 19.63 | 18.96 | 19.23 | 943K | -0.31% |
| 2026-04-09 | 19.37 | 19.73 | 19.05 | 19.29 | 1.29M | -1.68% |
| 2026-04-08 | 20.11 | 20.29 | 19.27 | 19.62 | 1.03M | +1.08% |
| 2026-04-07 | 19.23 | 19.53 | 18.80 | 19.41 | 1.12M | +0.15% |
| 2026-04-06 | 20.60 | 20.80 | 19.23 | 19.38 | 1.76M | -6.15% |
| 2026-04-02 | 19.16 | 20.65 | 18.92 | 20.65 | 1.59M | +4.93% |
| 2026-04-01 | 19.56 | 19.98 | 19.33 | 19.68 | 1.91M | +2.50% |
| 2026-03-31 | 18.90 | 19.44 | 18.74 | 19.20 | 2.16M | +6.19% |
| 2026-03-30 | 18.25 | 18.46 | 17.86 | 18.08 | 1.61M | -0.44% |
| 2026-03-27 | 19.59 | 19.74 | 18.10 | 18.16 | 3.05M | -7.98% |
| 2026-03-26 | 22.53 | 22.58 | 19.73 | 19.73 | 3.42M | -12.17% |
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Start ComparisonDNLI — Frequently Asked Questions
Quick answers to the most common questions about buying DNLI stock.
How has DNLI stock performed recently?
DNLI returned +37.6% over the past year, beating its 5-year annualized CAGR of -18.3%. The stock trades above its 200-day moving average, confirming the uptrend.
What is DNLI's all-time high price?
Denali Therapeutics Inc. reached $93.94 on 2020-12-22. The 52-week high is $23.77. Current 1-year return of +37.6% places the stock closer to historical peaks.
Where can I download DNLI historical price data?
This page provides DNLI daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2017-2026, downloadable in CSV format.