Free cash flow remains deeply negative with quarterly outflows averaging $2.1 million, and an OCF/NI ratio of 1.34 in 2026Q1 suggests that non-cash expenses are failing to offset the underlying cash burn.
| Cash from Operations | -8.3M | -7.76B | -11.16M | -6.41M | -8.83M | -5.69M | -4.03M | -3.92M |
| Operating CF Margin % | - | - | - | - | - | - | - | - |
| Operating CF Growth % | 46.85% | -69393.82% | -74.18% | 27.45% | -55.17% | -41.33% | -2.71% | - |
| Net Income | -7.1M | -7.56B | -12.29M | -7.79M | -9.61M | -7.9M | -3.24M | -4.72M |
| Depreciation & Amortization | 0 | 0 | 0 | 0 | 0 | 0 | 322 | 1.35K |
| Stock-Based Compensation | 77.07K | 143.73M | 657.65K | 522.08K | 930.33K | 1.91M | 0 | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 72.75K | -342.39M | 0 | 0 | 0 | 14.13K | -36.49K | 872.72K |
| Working Capital Changes | -1.35M | -342.73K | 466.86K | 863.68K | -153.58K | 289.55K | -755.85K | -74.99K |
| Change in Receivables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | -93.09K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | -541.25K | -388.06K | -108.51K | 369.33K | -18.54K | 410.97K | -232.91K | 122.42K |
| Cash from Investing | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Expenditures | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| CapEx % of Revenue | - | - | - | - | - | - | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Financing | 5.53M | 12.12B | 6.89M | 7.61M | 4.28M | 15.96M | 2.57M | 4.73M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 1.01M | 2.3M | -626.17K |
| Equity Issued (Net) | 5.53M | 12.12M | 6.89M | 7.61M | 4.28M | 14.96M | 268.75K | 5.36M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -367 | -367 | -828 | -40 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | 12.11B | 1.11K | 187 | 287 | 0 | 0 | 0 |
| Net Change in Cash | -2.77M | 4.36B | -4.28M | 1.2M | -4.56M | 10.27M | -1.46M | 812.19K |
| Free Cash Flow | -8.3M | -7.76B | -11.16M | -6.41M | -8.83M | -5.69M | -4.03M | -3.92M |
| FCF Margin % | - | - | - | - | - | - | - | - |
| FCF Growth % | 20.1% | -69393.82% | -74.18% | 27.45% | -55.17% | -41.33% | -2.71% | - |
| FCF per Share | -2.15 | -8375.76 | -72.96 | -328.73 | -127.91 | -109.38 | -1160.96 | -1130.34 |
| FCF Conversion (FCF/Net Income) | 1.17x | 1026.33x | 0.91x | 0.82x | 0.92x | 0.72x | 1.24x | 0.83x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 1.42K | 56.71K | 99.01K |
| Taxes Paid | 0 | 0 | 950 | 950 | 950 | 1.4K | 3.27K | 1.14K |
Clinical trial funding shortfall
According to recent SEC filings, Dermata's operating cash flow consistently trails net income, with the OCF/NI ratio reaching 1.34 in 2026Q1, indicating that non-cash expenses and working capital fluctuations are failing to bridge the gap between accounting losses and actual cash outflows for the clinical-stage firm.
The persistent divergence between net income and operating cash flow suggests that the company's reported losses do not fully capture the cash-intensive nature of its clinical development. Investors should monitor this relationship, as the inability to generate positive operating cash flow necessitates a reliance on external financing to cover ongoing R&D obligations.
As reported in financial statements, Dermata's free cash flow trajectory remains firmly in negative territory, with quarterly outflows averaging approximately $2.1 million over the last ten periods, reflecting the company's status as a pre-revenue entity entirely dependent on external capital to fund its clinical pipeline.
The lack of positive free cash flow is an expected characteristic of a clinical-stage biotechnology firm, yet the consistency of these outflows highlights the absence of any self-sustaining operational model. This trajectory implies that the company will continue to experience significant cash erosion until a commercial product or licensing milestone is achieved.
Based on EDBL's reported figures, working capital changes have been highly erratic, swinging from a $1.0 million outflow in 2025Q2 to a $858.2K inflow in 2023Q4, which suggests that the company's cash position is sensitive to the timing of vendor payments and clinical trial-related accruals.
The volatility in working capital movements indicates that management is likely managing cash outflows by timing payments to CROs and other service providers. This practice may provide temporary liquidity relief but does not address the underlying structural deficit inherent in the company's current business model.
As disclosed in historical filings, Dermata's capital deployment has been limited to minor share repurchases and operational funding, with no evidence of dividend payments or strategic acquisitions, underscoring a corporate strategy that prioritizes basic survival over long-term capital return or inorganic growth initiatives.
The absence of meaningful capital deployment activities suggests that all available resources are being funneled into the Phase 3 clinical program. Investors should interpret this as a clear signal that the company lacks the financial flexibility to pursue anything other than its core R&D objectives.
Based on the provided financial data, the cash flow statement masks the true extent of shareholder value erosion, as stock-based compensation and frequent equity raises are not fully reflected in the operational cash burn, despite their significant impact on the company's overall capital structure.
The reliance on equity-based financing to offset cash burn is a critical factor that the standard cash flow statement may understate. Analysts should look beyond the reported cash flow figures to understand how the company's financing decisions are impacting the long-term equity value for existing shareholders.
Quick answers to the most common questions about buying DRMA stock.
Dermata Therapeutics, Inc. (DRMA) generated $-7757.6M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Dermata Therapeutics, Inc. (DRMA) reported negative free cash flow of $7.76B in 2025, indicating capital requirements exceeded cash from operations.
Dermata Therapeutics, Inc. (DRMA) spent $0.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Dermata Therapeutics, Inc. (DRMA) spent $0.0M on share repurchases. This shows the company's commitment to returning capital to its equity investors.