Last 47 quarters of trend data · Healthcare · Life Science Tools
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -1.62 | — | — | — | — | — | — | — | — | — | — | — | — | — | 92.71 | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 3.57 | 8.49 | 6.72 | 32.53 | 8.74 | 16.08 | 55.09 | 15.69 | 3.92 | 28.08 | 35.97 | 16.89 | 34.83 | 16.61 | 13.09 | 11.81 | 15.41 | 32.73 | 32.79 | 101.28 | 56.33 |
| — | -47.2% | -87.8% | +107.3% | +123.1% | -42.8% | +53.2% | -7.1% | -88.7% | +69.1% | +174.9% | +43.0% | +126.0% | -49.3% | -60.1% | -88.3% | -72.6% | +23.6% | -60.0% | -5.2% | -54.9% | |
| P/B Ratio | 9.00 | — | — | 24.88 | 15.62 | — | 43.68 | 20.77 | 8.99 | 13.68 | 10.66 | 7.89 | 7.23 | 6.19 | 4.74 | 3.17 | 4.30 | 6.36 | 5.19 | 6.90 | 7.13 |
| — | — | — | +19.8% | +73.7% | — | +309.8% | +163.2% | +24.4% | +121.1% | +125.0% | +149.0% | +68.1% | -2.6% | -8.6% | -54.1% | -39.7% | +48.3% | -11.9% | +32.8% | +2.8% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | 3333975.77 | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | -88.3% | -2.4% | 28.7% | -63.2% | 78.1% | -32.4% | -62.6% | 56.8% | 79.8% | 21.8% | 57.0% | 49.0% | 73.3% | 5.3% | 25.7% | 5.3% | 31.5% | 37.6% | 37.6% | -5.9% | 43.4% |
| — | +92.6% | +145.9% | -211.1% | -2.1% | -248.9% | -209.8% | +16.0% | +8.8% | +311.8% | +121.9% | +828.9% | +133.1% | -85.9% | -31.7% | +190.1% | -27.4% | +227.3% | +148.1% | -122.4% | +20.8% | |
| Operating Margin | -579.9% | -213.7% | -172.1% | -646.9% | -165.3% | -373.1% | -1093.7% | -187.2% | -10.4% | -529.3% | -635.2% | -315.8% | -433.2% | -273.6% | -209.7% | -301.1% | -211.9% | -503.8% | -423.3% | -1345.7% | -479.7% |
| — | +42.7% | +84.3% | -245.6% | -1497.2% | +29.5% | -72.2% | +40.7% | +97.6% | -93.5% | -203.0% | -4.9% | -104.5% | +45.7% | +50.5% | +77.6% | +55.8% | -22.1% | +41.3% | -105.2% | +22.5% | |
| Net Margin | -597.6% | -221.0% | -175.9% | -664.9% | -169.7% | -387.0% | -1107.4% | -189.7% | -10.4% | -530.0% | -600.6% | -301.8% | -406.6% | -257.2% | -97.8% | -288.6% | -205.7% | -499.3% | -384.3% | -1345.0% | -247.5% |
| — | +42.9% | +84.1% | -250.4% | -1532.4% | +27.0% | -84.4% | +37.1% | +97.4% | -106.1% | -514.1% | -4.6% | -97.7% | +48.5% | +74.6% | +78.5% | +16.9% | -21.6% | +46.3% | -137.4% | +58.8% |
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -397.8% | — | -474.0% | -81.6% | -190.2% | -910.8% | -119.5% | -52.7% | -6.2% | -53.2% | -38.7% | -30.6% | -19.4% | -21.8% | -8.7% | -18.1% | -13.8% | -22.0% | -14.3% | -20.9% | -7.6% |
| — | — | -296.7% | -54.8% | -2976.0% | -1610.9% | -209.0% | -72.2% | +68.1% | -144.7% | -342.5% | -69.1% | -40.4% | +0.9% | +39.0% | +13.4% | -81.6% | -39.4% | -17.7% | -211.8% | +5.4% | |
| ROA | -74.1% | -29.6% | -22.0% | -14.5% | -19.9% | -22.4% | -22.7% | -15.0% | -1.9% | -17.5% | -19.2% | -23.7% | -15.9% | -18.0% | -7.2% | -14.8% | -11.2% | -18.4% | -12.5% | -18.7% | -6.8% |
| — | -32.3% | +3.2% | +3.1% | -950.9% | -27.5% | -18.3% | +36.9% | +88.0% | +2.7% | -166.6% | -59.8% | -42.4% | +2.0% | +42.4% | +20.5% | -63.6% | -30.9% | -10.8% | -194.2% | +10.7% | |
| ROIC | -396.9% | -425.9% | -247.1% | -104.7% | -99.3% | -78.2% | -153.8% | -59.0% | -5.6% | -122.6% | — | — | -72.9% | -45.4% | -31.6% | -30.1% | -28.1% | -61.7% | -62.2% | -58.1% | -28.7% |
| — | -444.7% | -60.7% | -77.5% | -1684.7% | +36.2% | — | — | +92.4% | -170.3% | — | — | -159.6% | +26.5% | +49.2% | +48.2% | +2.2% | -131.8% | -155.3% | -172.2% | -111.2% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 4.11 | — | — | 4.11 | 1.94 | — | 5.48 | 2.05 | 1.57 | 1.76 | 1.32 | 0.02 | 0.02 | — | — | — | — | — | — | — | — |
| — | — | — | +100.2% | +23.4% | — | +316.0% | +8704.6% | +8028.1% | — | — | — | — | — | — | — | — | — | — | — | — | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | 45643.00 | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 2.68 | 1.65 | 2.42 | 2.68 | 2.85 | 2.02 | 3.98 | 4.01 | 5.15 | 5.39 | 5.54 | 3.58 | 6.24 | 5.53 | 6.83 | 5.48 | 6.25 | 4.98 | 8.89 | 8.22 | 12.01 |
| — | -18.4% | -39.2% | -33.1% | -44.6% | -62.5% | -28.2% | +12.1% | -17.5% | -2.6% | -18.8% | -34.6% | -0.3% | +11.0% | -23.2% | -33.3% | -47.9% | -37.3% | -17.6% | -55.1% | -33.7% | |
| Quick Ratio | 2.68 | 1.65 | 2.42 | 2.68 | 2.85 | 2.02 | 3.98 | 4.01 | 5.15 | 5.39 | 5.54 | 3.58 | 6.24 | 5.53 | 6.83 | 5.48 | 6.25 | 4.98 | 8.89 | 8.22 | 12.01 |
| — | -18.4% | -39.2% | -33.1% | -44.6% | -62.5% | -28.2% | +12.1% | -17.5% | -2.6% | -18.8% | -34.6% | -0.3% | +11.0% | -23.2% | -33.3% | -47.9% | -37.3% | -17.6% | -55.1% | -33.7% | |
| Interest Coverage | -15.15 | -18.42 | -16.90 | -12.70 | -21.99 | -14.76 | -16.85 | -11.29 | -0.59 | -13.49 | -60.91 | — | — | — | — | — | — | — | — | — | — |
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Includes 30+ ratios · 47 years · Updated daily
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Quick answers to the most common questions about buying DYAI stock.
Dyadic International, Inc.'s current P/E is -1.6x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Dyadic International, Inc.'s current operating margin is -579.9%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Dyadic International, Inc.'s business trajectory between earnings reports.