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ENGNenGene Holdings Inc.
$1.75$90M
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HomeStocksENGNFinancials

enGene Holdings Inc. (ENGN) Financials

5Y historyFree accessUpdated daily

The company remains pre-revenue, with quarterly R&D spending intensifying to $22.2 million in 2026Q2 as it prioritizes clinical development over operational profitability.

ENGN Income Statement

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly
MetricTTMOct'25Oct'24Oct'23Oct'22Oct'21
Sales/Revenue000000
Revenue Growth %------
Cost of Goods Sold369K00000
COGS % of Revenue------
Gross Profit-369K00000
Gross Margin %------
Gross Profit Growth %------
Operating Expenses132.21M123.17M62.3M26.06M19.43M15.87M
OpEx % of Revenue------
Selling, General & Admin35.41M28.68M23.98M8.47M3.26M3.15M
SG&A % of Revenue------
Research & Development98.75M94.48M38.31M16.46M15.47M12.46M
R&D % of Revenue------
Other Operating Expenses-676K001.13M700K253K
Operating Income-68.64M-123.17M-62.3M-26.06M-19.43M-15.87M
Operating Margin %------
Operating Income Growth %--97.71%-139.05%-34.14%-22.41%-
EBITDA-67.97M-122.66M-61.97M-25.89M-19.19M-15.6M
EBITDA Margin %------
EBITDA Growth %22.38%-97.92%-139.42%-34.89%-23.02%-
D&A (Non-Cash Add-back)670K509K323K175K238K272K
EBIT-126.61M-114.31M-52.36M-94.95M-23.02M-18.42M
Net Interest Income6.63M6.43M7.62M-3.84M-1.29M-5M
Interest Income4.29M9.43M10.41M1.12M129K25K
Interest Expense2.98M2.99M2.8M4.95M1.42M5.02M
Other Income/Expense1.99M5.86M7.14M-73.84M-5.01M-7.57M
Pretax Income-66.65M-117.3M-55.16M-99.9M-24.44M-23.44M
Pretax Margin %------
Income Tax-258K0-19K17K22K0
Effective Tax Rate %0.39%0%0.03%-0.02%-0.09%0%
Net Income-66.4M-117.3M-55.14M-99.92M-24.46M-23.44M
Net Margin %------
Net Income Growth %16.88%-112.73%44.81%-308.46%-4.36%-
Net Income (Continuing)-66.4M-117.3M-55.14M-99.92M-24.46M-23.44M
Discontinued Operations000000
Minority Interest000000
EPS (Diluted)-0.95-2.29-1.46-4.240.00-0.01
EPS Growth %-109.52%-56.85%65.57%-113.29%-
EPS (Basic)--2.29-1.46-4.240.00-0.01
Diluted Shares Outstanding69.72M51.12M44.64M23.56M15.81M15.81M
Basic Shares Outstanding69.72M51.12M44.64M23.56M15.81M15.81M
Dividend Payout Ratio------

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Clinical trial funding shortfall

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q2)

Escalating R&D Expenditure Intensity

As reported in recent financial statements, enGene's quarterly R&D spending surged to $22.2 million by 2026Q2, reflecting the intensifying capital requirements of the LEGEND clinical trial as the company attempts to advance its proprietary DDX delivery platform toward potential commercialization in the competitive NMIBC oncology space.

The consistent upward trend in R&D costs suggests that the company is reaching a critical phase in its clinical development timeline, necessitating higher site-related expenditures. Investors should monitor whether this spending trajectory remains sustainable given the current cash position, as the lack of revenue leaves the firm entirely dependent on external financing to cover these operational outflows.

Non-Operating Noise Obscures Performance

Based on the company's 2026Q2 income statement, the reported net income of $30.2 million appears to be heavily influenced by non-operating adjustments rather than core operational success, as the firm remains pre-revenue and continues to incur significant losses from its ongoing clinical development and administrative activities.

The sudden swing to positive net income in the most recent quarter warrants further investigation, as it likely reflects non-cash accounting adjustments related to the SPAC merger or warrant revaluations. Analysts should look past these headline figures to focus on the underlying cash burn, which remains the most accurate indicator of the company's financial health.

Operating Leverage Remains Highly Constrained

According to the provided quarterly data, enGene's operating expenses have scaled significantly, with SG&A costs reaching $9.8 million in 2026Q2, indicating that the company is building out its administrative and operational infrastructure well in advance of any potential revenue generation from its lead gene therapy candidate.

The lack of revenue means that operating leverage is currently non-existent, as every dollar spent on SG&A and R&D directly increases the net loss. This structure implies that the company will require a massive, non-linear increase in future sales to achieve break-even, assuming the clinical program successfully reaches the commercialization stage.

Sustainability of Clinical Funding Runway

Based on the reported figures, the company's cash burn rate has accelerated alongside its clinical trial progression, raising significant questions about the adequacy of its current capital reserves to reach pivotal data readouts without resorting to dilutive equity financing in the near-to-medium term for shareholders.

Short-sellers may focus on the widening gap between R&D intensity and the company's limited cash runway, which appears to be under pressure. If the LEGEND trial encounters any regulatory delays or requires larger patient cohorts, the financial strain may necessitate a capital raise that could significantly dilute existing equity holders.

ENGN — Frequently Asked Questions

Quick answers to the most common questions about buying ENGN stock.

What was enGene Holdings Inc.'s (ENGN) revenue in 2025?

For fiscal year 2025, enGene Holdings Inc. (ENGN) reported total revenue of $0.0M.

Is enGene Holdings Inc. (ENGN) profitable?

enGene Holdings Inc. (ENGN) reported a net loss of $117.3M for the fiscal year ending 2025.