Amicus Therapeutics, Inc. (FOLD) P/E Ratio History
Insufficient DataInsufficient historical P/E data to classify valuation. · Data 2026–2026
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P/E Ratio Analysis
As of September 24, 2026, Amicus Therapeutics, Inc. (FOLD) trades at a price-to-earnings ratio of -164.8x, with a stock price of $14.49 and trailing twelve-month earnings per share of $-0.09.
Compared to the Healthcare sector median P/E of 23.7x, FOLD trades at a 795% discount to its sector peers. The sector includes 225 companies with P/E ratios ranging from 0.0x to 167.0x.
Relative to the broader market, FOLD trades at a notable discount to the S&P 500 median P/E of 25.3x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our FOLD DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
FOLD Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
FOLD P/E vs Peers
Commercial Rare Disease Biopharma peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $12B | 34.6 | - | -19% | |
| $10B | 50.0 | - | +128% | |
| $4B | 11.1 | - | +68% | |
| $5B | 8.0Lowest | - | +264% | |
| $6B | 48.7 | - | +2886%Best | |
| $44B | 34.2 | 0.84Best | +5% |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
FOLD Chart Terminal
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Live Breakouts Feed
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Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
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Peer Comparison
Compare growth, multiples, and margins vs sector.
FOLD — Frequently Asked Questions
Quick answers to the most common questions about buying FOLD stock.
What is FOLD's P/E ratio?
Amicus Therapeutics, Inc. (FOLD) trailing twelve-month P/E ratio is -164.8x, based on TTM diluted EPS of $-0.09. The 5-year average P/E is N/A and the historical range spans N/A to N/A.
Is FOLD stock overvalued or undervalued?
FOLD current P/E: -164.8x. 5-year average P/E: N/A. Percentile: N/A.
Is FOLD stock expensive?
FOLD is fairly valued relative to its own history. The current P/E of -164.8x is near the 5-year average of N/A (N/A percentile of historical range).
What is FOLD's historical P/E range?
Over the past 5 years, FOLD's P/E ratio has ranged from N/A to N/A, with a median of N/A and an average of N/A. The current P/E of -164.8x places the stock at the N/A percentile of this range. Full historical data spans 2026–2026.
How does FOLD's P/E compare to the S&P 500?
FOLD trades at -164.8x P/E versus the S&P 500 median of 25.3x. The 751% discount to the market suggests lower growth expectations or perceived higher risk.
How does FOLD's valuation compare to Healthcare peers?
Amicus Therapeutics, Inc. P/E of -164.8x compares to the Healthcare sector median of 23.7x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.
What is FOLD's PEG ratio?
FOLD PEG ratio is N/A, based on a P/E of -164.8x and EPS growth of 51.2%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is FOLD's earnings yield?
FOLD earnings yield is N/A, the inverse of its -164.8x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.