Last 23 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
HCW Biologics Inc.'s quarterly P/E stands at 0.0x.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -0.10 | 0.04 | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 41.92 | 0.03 | 18.85 | 133.96 | 269.73 | 24873.71 | 438.23 | 478.53 | 395.44 | 578.15 | 334.41 | 800.15 | 1251.21 |
| — | -100.0% | -95.7% | -72.0% | -31.8% | +4202.3% | +31.0% | -40.2% | -68.4% | -95.2% | -34.7% | +76.4% | -27.9% | |
| P/B Ratio | 0.83 | 0.13 | 0.74 | — | — | — | — | — | — | 298.11 | 131.56 | 114.40 | 109.04 |
| — | — | — | — | — | — | — | — | — | +383.6% | +79.3% | +48.3% | +59.7% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | 0.45 | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | 0.47 | 1.82 | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
HCW Biologics Inc.'s operating margin was 49.5% in Q1 2026, up 10961.7 pp QoQ and up 38860.9 pp YoY. This marks the 4th consecutive quarter of margin expansion, signaling a sustained improvement in operating efficiency. The trailing four-quarter average of -21186.4% lags the current quarter, suggesting the recent improvement is above-trend. Gross margin expanded 399.2% YoY, indicating pricing power or improving input costs.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 20.0% | 99.8% | 20.0% | 20.0% | 20.0% | 20.0% | 20.0% | 20.0% | 29.2% | 54.6% | -377.4% | 20.5% | 19.3% |
| — | +399.2% | -0.0% | -0.0% | -31.4% | -63.3% | +105.3% | -2.4% | +50.8% | +82.3% | -1987.2% | +2.4% | -47.4% | |
| Operating Margin | -20757.6% | 49.5% | -10912.3% | -20995.9% | -52886.7% | -38811.5% | -800.3% | -865.4% | -2445.8% | -665.1% | -813.3% | -595.2% | -724.2% |
| — | +100.1% | -1263.5% | -2326.2% | -2062.3% | -5735.5% | +1.6% | -45.4% | -237.7% | +94.8% | -92.5% | -167.9% | +6.4% | |
| Net Margin | -14677.1% | 63.2% | 2662.8% | -29183.2% | -29431.0% | -43373.6% | -854.4% | -915.1% | -2469.1% | -662.8% | -806.7% | -578.9% | -691.1% |
| — | +100.1% | +411.7% | -3089.0% | -1092.0% | -6443.8% | -5.9% | -58.1% | -257.3% | +94.5% | -99.7% | -167.6% | +10.6% |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -287.9% | 96.9% | 218.8% | — | — | — | — | — | -1252.0% | -67.3% | -57.2% | -18.8% | -14.1% |
| — | — | — | — | — | — | — | — | -8801.4% | -364.7% | -322.3% | -113.4% | -91.5% | |
| ROA | -29.1% | 15.9% | 2.9% | -16.8% | -7.0% | -7.8% | -11.9% | -14.6% | -53.4% | -25.3% | -33.3% | -13.2% | -10.4% |
| — | +305.0% | +124.2% | -14.6% | +86.9% | +69.3% | +64.3% | -11.2% | -414.8% | -125.7% | -201.7% | -65.9% | -45.3% | |
| ROIC | -171.1% | 25.9% | -37.1% | -57.2% | -60.6% | -45.2% | -116.1% | -125.8% | -145.4% | -38.5% | -45.7% | -16.3% | -14.0% |
| — | +157.3% | +68.0% | +54.5% | +58.3% | -17.6% | -154.0% | -674.3% | -938.3% | -101.5% | -138.1% | -45.0% | -66.4% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
HCW Biologics Inc.'s Debt/EBITDA ratio is 1.9x — comfortably within a safe range. The current ratio has improved 23.5% YoY to 0.09x, strengthening the short-term liquidity position.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 2.46 | 1.14 | 2.46 | — | — | — | — | — | — | 0.96 | 0.47 | 0.27 | 0.23 |
| — | — | — | — | — | — | — | — | — | +390.7% | +173.5% | +80.3% | +3841.6% | |
| Debt / EBITDA | — | 1.95 | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 0.11 | 0.09 | 0.11 | 0.06 | 0.11 | 0.07 | 0.19 | 0.07 | 0.10 | 0.46 | 0.73 | 2.56 | 4.36 |
| — | +23.5% | -43.6% | -15.1% | +5.0% | -84.9% | -73.7% | -97.3% | -97.6% | -93.0% | -93.6% | -79.6% | -85.6% | |
| Quick Ratio | 0.11 | 0.09 | 0.11 | 0.06 | 0.11 | 0.07 | 0.19 | 0.07 | 0.10 | 0.46 | 0.73 | 2.56 | 4.36 |
| — | +23.5% | -43.6% | -15.1% | +5.0% | -84.9% | -73.7% | -97.3% | -97.6% | -93.0% | -93.4% | -79.6% | -85.6% | |
| Interest Coverage | -5.37 | 29.61 | 4.17 | -30.94 | -6.98 | -6.52 | -10.47 | -16.47 | -94.70 | — | — | -50.71 | -44.07 |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 23 years · Updated daily
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Quick answers to the most common questions about buying HCWB stock.
HCW Biologics Inc.'s current P/E is -0.1x. The average P/E over the last 1 quarters is 0.0x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
HCW Biologics Inc.'s current operating margin is -20757.6%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking HCW Biologics Inc.'s business trajectory between earnings reports.