Despite operational volatility, the company maintains strong liquidity with $603.1 million in cash reserves and consistent free cash flow margins averaging between 35% and 60% over the last ten quarters.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 |
|---|
| Cash from Operations | 183.59M | 196.93M | 188.69M | 141.06M | 201.73M | 363.81M | 313.11M | 257.46M | 223.53M | 141.75M | 60.98M | 10.13M | -130.72M | -129.6M | -127.95M | -88.34M | -75.14M | -58.06M | -99.91M | -104.37M | -104.79M | -58.65M | -47.82M | -31.68M | -58.6M |
| Operating CF Margin % | - | 46.32% | 52.6% | 45.44% | 60.88% | 92.84% | 92.97% | 98.64% | 85.64% | 65.26% | 45.66% | 18.78% | -1550.14% | -2859.71% | -2279.6% | -360.39% | -310.22% | -238.22% | -432.59% | -474.38% | -535% | -486.52% | -534.93% | -878.67% | -37564.74% |
| Operating CF Growth % | -32.46% | 4.37% | 33.76% | -30.07% | -44.55% | 16.19% | 21.62% | 15.18% | 57.7% | 132.43% | 501.95% | 107.75% | -0.86% | -1.29% | -44.85% | -17.56% | -29.42% | 41.88% | 4.27% | 0.4% | -78.69% | -22.63% | -50.98% | 45.95% | - |
| Net Income | 504.34M | 271.17M | 23.39M | 179.72M | 220.26M | 368.84M | 293.81M | 190.99M | 406.33M | 134.27M | 59.54M | -18.76M | -168.46M | -170.7M | -18.54M | -115.34M | -83.86M | -85.3M | -93.64M | -160M | -166.04M | -143.16M | -102.65M | -70.58M | -79.23M |
| Depreciation & Amortization | 86.84M | 40.23M | 39.85M | 35.7M | 19.51M | 13.83M | 0 | 13.87M | 13.87M | 13.98M | 13.95M | 13.93M | 12.18M | 8.2M | 7.33M | 7.58M | 6.34M | 5.54M | 6.96M | 4.06M | 4.2M | 4.11M | 4.81M | 5.21M | 5.12M |
| Stock-Based Compensation | 18.59M | 9.45M | 6.37M | 5.84M | 7.35M | 2.02M | 1.7M | 2.06M | 3.23M | 9.83M | 8.3M | 6.87M | 27.39M | 25.69M | 23.78M | 24.92M | 19.01M | 20M | 18.02M | 22.49M | 21.83M | 5.62M | 8.52M | 0 | 0 |
| Deferred Taxes | 47.04M | 43.85M | -12.62M | 4.4M | 25.01M | 76.43M | 60.42M | 41.88M | -196.05M | 7.15M | 0 | 0 | 5.49M | 1.42M | 0 | 0 | 33K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -523.69M | -143.6M | 138.62M | -59.81M | -77.27M | -80.43M | -28.5M | 5.57M | 12.91M | 4.79M | 1.16M | 24.94M | 22.93M | 17K | 187K | 16K | 8K | -13K | 77K | 533K | 761K | 582K | 4.08M | 4.06M | 6.49M |
| Working Capital Changes | -27.06M | -24.16M | -6.93M | -24.79M | 6.87M | -16.87M | -14.32M | 3.1M | -16.76M | -28.28M | -21.96M | -16.85M | -30.25M | 5.77M | -140.71M | -5.51M | -16.67M | 1.71M | -31.33M | 28.54M | 34.46M | 74.21M | 37.42M | 29.64M | 9.01M |
| Change in Receivables | -15.38M | -6.95M | -2.29M | -20M | 9.79M | -16.78M | -14.5M | 3.86M | -12.75M | -23.69M | -20.62M | -15.68M | -7.3M | -1.42M | -841K | 0 | -448K | 0 | -3.52M | -177K | 12K | 2.37M | -3.77M | 1.09M | -2.15M |
| Change in Inventory | -3.77M | -12.92M | -6.81M | -12M | 280K | 0 | 0 | -664K | -3.43M | 0 | 0 | 0 | -1.91M | -3.1M | -4.82M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 266K | 2.83M | -4.58M | 3.78M | 92K | -39K | 56K | -1K | -590K | 473K | -690K | -238K | -7.7M | 1.61M | -1.48M | 3.31M | -236K | 0 | -8.22M | -11.38M | 7.2M | 9.66M | 6.68M | 0 | 0 |
| Cash from Investing | 112.18M | 40.5M | -63.79M | -66.76M | -56.63M | 43.72M | -314.94M | -18M | 3.52M | -23.24M | -4.58M | 159.17M | -65.06M | -219.58M | -58.28M | -55.82M | -40.31M | 1.74M | -67.37M | 110.59M | -18.58M | 3.34M | -100.37M | -13.61M | 51.58M |
| Capital Expenditures | -2.74M | -1.13M | -270K | -411K | -67K | -1.3M | -13K | -12K | 0 | 0 | -278K | -7K | -689K | -87.73M | -2.59M | -3.63M | -861K | -744K | -1.03M | -9.82M | -5.71M | -3.44M | -2.08M | -763K | -6.99M |
| CapEx % of Revenue | 0.65% | 0.27% | 0.08% | 0.13% | 0.02% | 0.33% | 0% | 0% | - | - | 0.21% | 0.01% | 8.17% | 1935.88% | 46.14% | 14.8% | 3.55% | 3.05% | 4.46% | 44.62% | 29.14% | 28.56% | 23.32% | 21.16% | 4478.21% |
| Acquisitions | 19.94M | 0 | 0 | 0 | -33.2M | -235.81M | -102.86M | 17.99M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12K | 0 | 103K | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 29.01M | -929K | -3.9M | 0 | -56.63M | -20.98M | 0 | -17.99M | 0 | 0 | 0 | 0 | -134.03M | 100K | 160K | 575K | 557K | 2.88M | 281K | 1.18M | -443K | 1.09M | 4.75M | 1M | -4.75M |
| Cash from Financing | -11.78M | 8.55M | -13.45M | -171.84M | -55.57M | -452.5M | -29.79M | -23.78M | -237.97M | -163.19M | -97.57M | -106.92M | 149.07M | 397.84M | 236.31M | 25.6M | 231.25M | 11.59M | 173.12M | 7.83M | 145.97M | 3.68M | 213.85M | -27.76M | 66.71M |
| Debt Issued (Net) | -25K | -25K | 0 | -96.2M | 66.37M | 0 | 0 | -13.75M | -230M | -63.74M | -18.4M | 0 | 434.68M | 281.62M | -510K | -206K | -184K | -131K | 166.63M | -88K | -1.25M | -2.52M | -3.47M | -28.18M | 26.59M |
| Equity Issued (Net) | 8.39M | 8.58M | -13.45M | -75.64M | -8.59M | -393.04M | 344K | 538K | -1.93M | -99.63M | -78.21M | -27.83M | 48.92M | 153.02M | 236.38M | 25.81M | 231.43M | 11.72M | 6.49M | 7.91M | 147.22M | 6.21M | 217.32M | 418K | 40.12M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -11K | -80K | -281K | -960K | -87.33M | -56.99M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -4.61M | -4.67M | -14.92M | -75.81M | -8.59M | -394.21M | -92K | -89K | -3.07M | -99.63M | -79.17M | -27.83M | -5.66M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -20.15M | 0 | 0 | 0 | -113.35M | -59.46M | -30.13M | -10.55M | -5.96M | 459K | 0 | 8.24M | -277.54M | -36.8M | 441K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Net Change in Cash | 284M | 245.98M | 111.45M | -97.54M | 89.52M | -44.96M | -31.61M | 215.68M | -10.92M | -44.68M | -41.16M | 62.38M | -46.71M | 48.66M | 50.07M | -118.56M | 115.79M | -44.74M | 5.85M | 14.04M | 22.6M | -51.62M | 65.66M | -73.05M | 59.68M |
| Free Cash Flow | 180.85M | 195.8M | 188.42M | 140.65M | 201.66M | 362.51M | 313.1M | 257.45M | 223.53M | 141.75M | 60.71M | 10.12M | -131.41M | -217.34M | -130.54M | -91.97M | -76M | -58.81M | -100.94M | -114.19M | -110.5M | -62.09M | -49.91M | -32.44M | -65.59M |
| FCF Margin % | 42.64% | 46.06% | 52.53% | 45.3% | 60.86% | 92.51% | 92.96% | 98.63% | 85.64% | 65.26% | 45.45% | 18.77% | -1558.31% | -4795.59% | -2325.74% | -375.19% | -313.77% | -241.27% | -437.05% | -519% | -564.14% | -515.08% | -558.25% | -899.83% | -42042.95% |
| FCF Growth % | -7.72% | 3.92% | 33.96% | -30.25% | -44.37% | 15.78% | 21.62% | 15.17% | 57.7% | 133.5% | 499.62% | 107.7% | 39.54% | -66.48% | -41.95% | -21% | -29.24% | 41.74% | 11.6% | -3.34% | -77.97% | -24.4% | -53.85% | 50.54% | - |
| FCF per Share | 2.13 | 2.31 | 2.54 | 1.62 | 2.12 | 3.84 | 2.76 | 2.27 | 1.97 | 1.18 | 0.49 | 0.09 | -1.17 | -2.12 | -1.44 | -1.12 | -1.05 | -0.93 | -1.64 | -1.89 | -1.87 | -1.17 | -1.50 | -4.76 | -10.35 |
| FCF Conversion (FCF/Net Income) | 0.36x | 0.73x | 8.07x | 0.78x | 0.94x | 1.37x | 1.40x | 1.64x | 0.57x | 1.06x | 1.02x | -0.54x | 0.78x | 0.76x | 6.90x | 0.77x | 0.90x | 0.68x | 1.07x | 0.65x | 0.63x | 0.41x | 0.47x | 0.45x | 0.74x |
| Interest Paid | 0 | 0 | 10.36M | 0 | 11.74M | 0 | 9.93M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 11.79M | 0 | 53.85M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Commercialization execution uncertainty
According to recent SEC filings, Innoviva's operating cash flow to net income ratio has exhibited extreme volatility, ranging from -1.04 to 40.14, which suggests that reported net income is frequently decoupled from actual cash generation due to significant non-cash accounting adjustments and amortization of royalty rights.
The wide variance between net income and operating cash flow indicates that headline earnings are not a reliable proxy for liquidity. Investors should monitor the persistent gap between these figures, as it suggests that the company's accounting treatment of its GSK royalty assets creates substantial noise that obscures the underlying cash-generating capacity of the business.
As reported in financial statements, Innoviva has maintained a consistent free cash flow trajectory, with quarterly FCF margins averaging between 35% and 60% over the last ten quarters, demonstrating that the core royalty business continues to provide a stable foundation despite the company's recent expansion into operations.
While the company is actively deploying capital into higher-risk commercialization efforts, the FCF generation remains resilient. This stability appears to be a direct result of the high-margin nature of the GSK respiratory portfolio, which continues to offset the cash burn associated with the company's newer, more capital-intensive infectious disease product segment.
Based on EDBL's reported figures, Innoviva maintains an exceptionally low capital intensity, with CapEx to revenue ratios frequently remaining below 1.0%, confirming that the company's primary royalty-based business model requires virtually no ongoing investment to maintain its existing revenue streams from the GSK respiratory franchise.
The minimal requirement for maintenance CapEx is a critical differentiator that allows the company to preserve its cash position. Any future spikes in capital expenditure should be scrutinized as a potential signal that the company is shifting away from its low-overhead royalty roots toward a more asset-heavy, and potentially less efficient, operating model.
According to quarterly financial data, Innoviva has transitioned from modest share repurchases to a more aggressive M&A-focused capital deployment strategy, with net acquisition activity reaching $39.9M in 2025Q4, signaling a shift in management's priority toward building an internal operating platform rather than returning capital to shareholders.
This pivot toward M&A introduces significant execution risk, as the company attempts to scale its infectious disease segment using cash generated from its legacy royalty assets. Investors should monitor whether these acquisitions provide a sufficient return on invested capital, or if they represent a value-destructive attempt to diversify away from the core respiratory business.
Quick answers to the most common questions about buying INVA stock.
Innoviva, Inc. (INVA) generated $196.9M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Innoviva, Inc. (INVA) generated $195.8M in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Innoviva, Inc. (INVA) spent $1.1M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Innoviva, Inc. (INVA) spent $4.7M on share repurchases. This shows the company's commitment to returning capital to its equity investors.