Last 46 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -0.00 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 0.02 | 0.17 | 0.29 | 0.21 | 0.34 | 0.53 | 1.02 | 0.26 | 0.01 | 0.13 | 0.16 | 0.47 | 0.14 |
| — | -68.3% | -71.9% | -16.5% | +3843.2% | +316.9% | +535.4% | -45.2% | -93.7% | — | — | — | — | |
| P/B Ratio | — | — | 0.81 | 0.37 | 3.59 | 1.15 | 0.97 | 0.15 | 0.01 | 0.24 | 1.27 | 0.86 | 0.14 |
| — | — | -16.3% | +153.4% | +63891.7% | +379.6% | -24.1% | -83.0% | -96.0% | — | — | — | — | |
| P/FCF | 0.03 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Jaguar Health, Inc.'s operating margin was -656.6% in Q4 2025, down 421.9 pp QoQ and down 424.2 pp YoY. The trailing four-quarter average of -396.4% exceeds the current quarter, suggesting the latest result may reflect seasonal weakness or a one-off headwind. Gross margin contracted 41.4% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 67.2% | 49.3% | 64.6% | 82.3% | 76.7% | 84.1% | 82.6% | 84.3% | 81.7% | 70.1% | 81.7% | 81.7% | 82.5% |
| — | -41.4% | -21.8% | -2.4% | -6.1% | +20.0% | +1.1% | +3.3% | -1.0% | -7.2% | +1.5% | -3.2% | -0.2% | |
| Operating Margin | -398.8% | -656.6% | -234.8% | -268.8% | -425.5% | -232.5% | -233.7% | -264.5% | -349.4% | -328.6% | -312.4% | -302.8% | -499.2% |
| — | -182.5% | -0.5% | -1.6% | -21.8% | +29.3% | +25.2% | +12.6% | +30.0% | -70.4% | +0.6% | -36.5% | -11.5% | |
| Net Margin | -465.4% | -717.2% | -308.2% | -349.3% | -472.6% | -282.7% | -317.1% | -348.8% | -392.4% | -398.7% | -276.5% | -454.0% | -618.8% |
| — | -153.7% | +2.8% | -0.1% | -20.4% | +29.1% | -14.7% | +23.2% | +36.6% | -71.4% | +30.4% | -41.6% | +9.7% |
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | — | — | -169.1% | -270.0% | -285.7% | -101.3% | -61.3% | -56.9% | -96.1% | -290.5% | -214.7% | -180.2% | -387.1% |
| — | — | -175.9% | -374.5% | -197.3% | +65.1% | +71.5% | +68.4% | +75.2% | +57.0% | +45.5% | -4.5% | -114.8% | |
| ROA | -116.8% | -52.9% | -19.4% | -20.9% | -20.0% | -17.7% | -16.4% | -16.2% | -17.4% | -19.1% | -15.9% | -22.3% | -23.4% |
| — | -198.1% | -18.3% | -28.5% | -14.8% | +7.0% | -3.1% | +27.1% | +25.7% | -24.2% | +35.6% | -22.2% | +31.0% | |
| ROIC | -116.8% | -56.2% | -16.0% | -17.5% | -20.6% | -17.7% | -15.3% | -14.7% | -17.2% | -16.4% | -20.9% | -21.3% | -26.6% |
| — | -217.5% | -4.6% | -18.7% | -19.9% | -8.2% | +26.8% | +30.9% | +35.2% | +5.6% | +25.4% | -10.3% | +28.1% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has weakened 69.4% YoY to 0.50x, tightening the short-term liquidity position.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | — | 7.32 | 4.44 | 46.19 | 5.62 | 2.62 | 1.79 | 2.34 | 7.57 | 25.10 | 5.52 | 4.48 |
| — | — | +179.7% | +147.7% | +1874.7% | -25.7% | -89.6% | -67.5% | -47.8% | — | +171.1% | -53.8% | +10.4% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 0.50 | 0.50 | 0.81 | 0.95 | 1.08 | 1.63 | 1.84 | 2.10 | 1.89 | 2.00 | 1.77 | 0.97 | 1.04 |
| — | -69.4% | -55.9% | -54.4% | -43.0% | -18.3% | +4.1% | +115.4% | +81.9% | +171.7% | +89.3% | -4.6% | -30.2% | |
| Quick Ratio | 0.29 | 0.29 | 0.52 | 0.59 | 0.70 | 1.11 | 1.36 | 1.60 | 1.39 | 1.34 | 1.10 | 0.69 | 0.76 |
| — | -73.9% | -61.7% | -63.2% | -49.1% | -17.4% | +23.6% | +132.0% | +82.1% | +166.2% | +59.0% | -5.1% | -38.4% | |
| Interest Coverage | -565.60 | -148.29 | -1607.00 | — | — | — | — | — | -14.33 | -28.98 | -17.57 | -2.35 | -4.68 |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 46 years · Updated daily
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Jaguar Health, Inc.'s current P/E is -0.0x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Jaguar Health, Inc.'s current operating margin is -398.8%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Jaguar Health, Inc.'s business trajectory between earnings reports.