Free cash flow remains persistently negative with quarterly outflows between $10 million and $16 million, leaving the firm reliant on external financing to maintain its $161.2 million cash position.
| Metric | Jun'25 | Jun'24 | Jun'23 | Jun'22 | Jun'21 | Jun'20 | Jun'19 | Jun'18 | Jun'17 | Jun'16 | Jun'15 | Jun'14 | Jun'13 | Jun'12 | Jun'11 | Jun'10 | Jun'09 | Jun'08 | Jun'07 | Jun'06 | Jun'05 |
|---|
| Cash from Operations | -49.95M | -48.46M | -63.27M | -65.78M | -106.68M | -56.37M | -57.79M | -75.01M | -95.47M | -88M | -121.71M | -81.86M | -54.08M | -72.12M | 108.23M | -9.66M | -9.24M | -6.2M | -9.1M | -3.18M | -604.81K |
| Operating CF Margin % | -290.46% | -821.04% | -843.47% | -644.23% | -1430.81% | -175.29% | -345.59% | -432.57% | -3958.17% | -206.82% | -512.5% | -315.09% | -187.87% | -188.39% | 89.5% | -175593.85% | -1037.1% | -681.75% | -542.05% | -112.83% | -120.27% |
| Operating CF Growth % | -3.09% | 23.41% | 3.82% | 38.34% | -89.27% | 2.47% | 22.96% | 21.43% | -8.49% | 27.7% | -48.68% | -51.37% | 25.01% | -166.63% | 1220.65% | -4.55% | -48.93% | 31.86% | -185.9% | -426.42% | - |
| Net Income | -102.14M | -87.96M | -81.89M | -91.35M | -98.81M | -77.94M | -89.8M | -35.29M | -76.81M | -4.13M | -119.37M | -80.96M | -61.66M | -71.15M | 90.61M | -14.78M | -12.29M | -10.06M | -8.73M | -8.3M | -1.47M |
| Depreciation & Amortization | 6.4M | 4.67M | 4.11M | 4.38M | 4.26M | 3.67M | 2.14M | 2.65M | 3.06M | 2.19M | 1.96M | 1.12M | 772K | 378.58K | 178.88K | 153.28K | 119.83K | 156.76K | 62.52K | 43.58K | 18.98K |
| Stock-Based Compensation | 22.09M | 5.87M | 3.65M | 5.54M | 12.51M | 7.52M | 4.37M | 6.2M | 5.28M | 3.39M | 8.57M | 9.42M | 12.29M | 12.12M | 3.3M | 1.02M | 1.2M | 1.35M | 547.85K | 1M | 65.52K |
| Deferred Taxes | 330K | -191K | -212K | -235K | -819K | -9.41M | -8.96M | -30.66M | -13.4M | -86.69M | -13.14M | 1.49M | 4.99M | -25.25M | -106.2M | 2.65M | 991.75K | 72.49K | 824.53K | 2.32M | 376.71K |
| Other Non-Cash Items | 26.41M | 31.78M | 13.54M | 11.02M | -15.41M | 6.51M | 14.02M | -8.98M | 168K | -2.61M | -5.03M | -12.08M | -3.3M | 12.12M | 3.3M | 1.02M | 1.2M | 1.35M | 542 | -235.55K | 107.12K |
| Working Capital Changes | -3.04M | -2.63M | -2.47M | 4.87M | -8.42M | 13.29M | 20.44M | -8.93M | -13.76M | -144K | 5.31M | -853K | -7.18M | -339.4K | 117.04M | 283.51K | -456.68K | 938.99K | -1.81M | 1.98M | 297.23K |
| Change in Receivables | 6.29M | -15.47M | -118K | 140K | -1.74M | 890K | 4.97M | -6.09M | -859K | -531K | 252K | 2.64M | 2.12M | -3.96M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 826K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.05M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.02M | 14.76M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | 120K | -97K | -194K | -232K | -1.65M | -3.27M | -1M | -1.15M | 142K | -1.73M | -5.61M | -40.81M | -5.04M | 5.33M | 4.71M | -343.45K | 266.89K | -5.35M | -3.38M | -4.06M | -4.97M |
| Capital Expenditures | -680K | -271K | -314K | -232K | -1.65M | -2.25M | -279K | -201K | -311K | -922K | -2.72M | -37.92M | -2.84M | -2.71M | -461.55K | -87.11K | -170.02K | -100.96K | -181.85K | -153.48K | -752.61K |
| CapEx % of Revenue | 3.95% | 4.59% | 4.19% | 2.27% | 22.09% | 6.98% | 1.67% | 1.16% | 12.89% | 2.17% | 11.44% | 145.95% | 9.86% | 7.07% | 0.38% | 1583.87% | 19.09% | 11.1% | 10.83% | 5.44% | 149.66% |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | -1.03M | -721K | -952K | 0 | 0 | -2.33M | -33.37M | -1.41M | 0 | 3.45M | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 559K | -60K | 120K | -75K | 0 | -1.03M | -721K | -952K | 453K | -1M | 622K | -1.41M | -2.09M | 9.31M | 1.73M | -256.33K | 636.91K | 1.17M | 680.9K | 98.35K | -216.35K |
| Cash from Financing | 147.34M | 40.25M | 74.5M | -9.87M | 114.47M | 137.04M | 71.61M | 68.61M | 60.01M | 62.07M | 45.85M | 2.43M | 169.35M | 4.88M | 126.09M | 25.54M | 11.39M | 13.6M | 16.75M | 0 | 20.67M |
| Debt Issued (Net) | -9.77M | -13.52M | -2.66M | -6.33M | -2.93M | -1.63M | 43.57M | 31.7M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 1000K | 1000K | 1000K | 209K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 0 | 1000K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -4.1M | -11.63M | -11.48M | -3.75M | 5.2M | -6.28M | -2.22M | -3.66M | -1.93M | -6.48M | -439K | -41K | -5.53M | 0 | -770.31K | -1.26M | -548.29K | -537.6K | -805.09K | 0 | -1.99M |
| Net Change in Cash | 98.59M | -8.36M | 10.87M | -76.43M | 7.55M | 78.9M | 12.66M | -8M | -35.18M | -29.76M | -52.25M | -118.92M | 109.72M | -56.48M | 231.18M | 15.52M | 2.43M | 2.04M | 4.2M | -7.24M | 15.09M |
| Free Cash Flow | -50.68M | -48.79M | -63.58M | -66.01M | -108.33M | -58.61M | -58.07M | -75.21M | -95.78M | -88.92M | -124.42M | -119.78M | -56.92M | -74.82M | 107.77M | -9.74M | -9.41M | -6.3M | -9.28M | -3.34M | -1.36M |
| FCF Margin % | -294.71% | -826.65% | -847.66% | -646.5% | -1452.9% | -182.27% | -347.26% | -433.73% | -3971.06% | -208.98% | -523.94% | -461.04% | -197.73% | -195.46% | 89.12% | -177177.73% | -1056.19% | -692.84% | -552.88% | -118.27% | -269.93% |
| FCF Growth % | -3.88% | 23.27% | 3.68% | 39.06% | -84.83% | -0.93% | 22.79% | 21.47% | -7.72% | 28.54% | -3.88% | -110.44% | 23.93% | -169.43% | 1205.9% | -3.58% | -49.24% | 32.11% | -178.2% | -145.86% | - |
| FCF per Share | -0.42 | -0.49 | -0.76 | -0.97 | -1.79 | -1.11 | -1.17 | -1.62 | -1.78 | -1.65 | -2.31 | -2.23 | -1.06 | -1.39 | 2.00 | -0.18 | -0.17 | -0.12 | -0.17 | -0.06 | -0.03 |
| FCF Conversion (FCF/Net Income) | 0.49x | 0.55x | 0.77x | 0.72x | 1.08x | 0.72x | 0.64x | 2.13x | 1.24x | 21.32x | 1.02x | 1.01x | 0.88x | 1.01x | 1.19x | 0.65x | 0.75x | 0.62x | 1.04x | 0.38x | 0.41x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liquidity and regulatory binary
According to quarterly financial data, the OCF/NI ratio has fluctuated significantly, reaching 0.61 in 2025Q4, which highlights a persistent disconnect between accounting losses and the actual cash required to sustain the company's intensive clinical development and manufacturing validation efforts.
The gap between net income and operating cash flow suggests that non-cash items and working capital adjustments are not sufficient to bridge the fundamental deficit in the business model. Investors should monitor this conversion ratio closely, as it indicates that the company's reported losses are not merely accounting artifacts but represent a genuine, ongoing depletion of liquid resources.
As reported in recent financial statements, Mesoblast's free cash flow remains consistently negative, with quarterly outflows ranging between $10 million and $16 million, underscoring the company's reliance on external financing to fund its long-dated pipeline and high-cost clinical trial infrastructure.
The trajectory of free cash flow shows no signs of approaching break-even, reflecting the heavy burden of R&D and the lack of a self-sustaining commercial revenue base. This trend suggests that the company remains in a high-risk phase where cash preservation is secondary to the necessity of funding critical regulatory milestones.
Based on reported figures, capital expenditures remain remarkably low, peaking at only 7.1% of revenue in 2025Q4, which indicates that the company's primary cash drain is operational R&D rather than the physical infrastructure or heavy machinery typically associated with industrial manufacturing.
The low level of capital expenditure suggests that the company has not yet invested in the large-scale, internal manufacturing facilities that would be required for a successful U.S. commercial launch. This may imply that future capital requirements could spike significantly if the company is forced to build out its own production capacity to satisfy regulatory demands.
Data from recent quarters reveals erratic working capital movements, including a $5.3 million outflow in 2025Q4, which suggests that timing differences in milestone payments and operational payables are creating additional, unpredictable pressure on the company's already strained cash reserves.
The volatility in working capital appears to be a byproduct of the company's reliance on sporadic milestone-based revenue streams. This lack of predictability in cash inflows warrants further investigation, as it complicates management's ability to forecast liquidity needs and maintain a stable runway for ongoing clinical operations.
Quick answers to the most common questions about buying MESO stock.
Mesoblast Limited (MESO) generated $-50.0M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Mesoblast Limited (MESO) reported negative free cash flow of $50.7M in 2025, indicating capital requirements exceeded cash from operations.
Mesoblast Limited (MESO) spent $0.7M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.