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MPLTMapLight Therapeutics, Inc.
$34.30$1.6B
Overview & Verdict
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MPLT logoMapLight Therapeutics, Inc.(MPLT)Earnings, Financials & Key Ratios

MPLT•NASDAQ
$34.30
Price updated Jun 30, 2026
  • Revenue$0
  • EBITDA-$169M-104.9%
  • Net Income-$161M-107.7%
  • EPS (Diluted)-3.66-95.7%
  • ROE-56.19%+32.5%

MPLT Price & Volume

MapLight Therapeutics, Inc. (MPLT) stock price & volume — 10-year historical chart

Loading chart...

Accelerating Clinical Burn Pressures Capital Liquidity

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical Trial Funding Gap

Key Thesis Takeaways

  • MapLight Therapeutics remains a high-risk, pre-revenue biotechnology firm whose valuation is entirely contingent on the successful clinical progression of its sonelokimab pipeline.
  • The company faces significant capital intensity, with quarterly R&D expenditures surging to $53.7 million as of 2026Q1, necessitating potential dilutive financing to sustain operations.
  • Investors should monitor the narrowing liquidity runway, as the current $55.7 million cash balance may be insufficient to support the escalating burn rate required for late-stage regulatory milestones.

Verdict Logic

the company's accelerating quarterly cash burn of $51.2 million against a $55.7 million cash balance suggests an imminent liquidity shortfall that warrants extreme caution for long-term investors.

MPLT Growth Metrics

MapLight Therapeutics, Inc. (MPLT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-167.82%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-154.44%

Return on Capital

10 Years-92.27%
5 Years-92.27%
3 Years-84.16%
Last Year-57.88%

MPLT Recent Earnings

MapLight Therapeutics, Inc. (MPLT) EPS & revenue vs analyst estimates — last 3 quarters

Full history →
●Beat EPS 0/3 qtrs (0%)
Q2 2026Latest
May 14, 2026
Metric
Actual
Est
EPS
$1.34-39.3%
$0.96
Rev
—
—
Q2 2026
Mar 26, 2026
Metric
Actual
Est
EPS
$2.47-135.2%
$1.05
Rev
—
—
Q4 2025
Dec 4, 2025
Metric
Actual
Est
EPS
$37.18-2061.6%
$1.72
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 14, 2026
$1.34vs $0.96-39.3%
—
Q2 2026Mar 26, 2026
$2.47vs $1.05-135.2%
—
Q4 2025Dec 4, 2025
$37.18vs $1.72-2061.6%
—
Based on last 3 quarters of dataView full earnings history →

Latest MPLT News

Recent stock market news and headlines for MapLight Therapeutics, Inc. (MPLT)

GlobeNewsWire·5 days ago
MapLight Therapeutics Announces Changes to Board of Directors

SAN FRANCISCO and BOSTON, June 24, 2026 (GLOBE NEWSWIRE) -- MapLight Therapeutics, Inc. (Nasdaq: MPLT), a clinical-stage biopharmaceutical company focused on improving the lives of patients suffering from debilitating central nervous system (CNS) disorders, today announced the appointment of Martin Babler and Troy Cox to its Board of Directors following their election at the Company's Annual Meeting of Stockholders on June 23, 2026. Mr. Babler and Mr. Cox succeed Robert Malenka, M.D., Ph.D., and Jim Trenkle, Ph.D., who did not stand for re-election and have concluded their service on the Board. Mr. Babler has been appointed as a member of the Audit Committee, and Mr. Cox has been appointed Chair of the Nominating and Corporate Governance Committee.

Seeking Alpha·6 days ago
MapLight Therapeutics, Inc. (MPLT) Discusses Top Line Phase II IRIS Study Results for ML-004 in Autism Spectrum Disorder Transcript

MapLight Therapeutics, Inc. (MPLT) Discusses Top Line Phase II IRIS Study Results for ML-004 in Autism Spectrum Disorder Transcript

Benzinga·Jun 22, 2026
MapLight Therapeutics Autism Drug Shows Mixed Potential In Adolescents

MapLight Therapeutics Inc. (NASDAQ:MPLT) reported mixed topline results from its Phase 2 IRIS study of ML-004 in patients with autism spectrum disorder.

GlobeNewsWire·Jun 22, 2026
MapLight Announces Topline Results from Phase 2 IRIS Study for ML-004 in Autism Spectrum Disorder

SAN FRANCISCO and BOSTON, June 22, 2026 (GLOBE NEWSWIRE) -- MapLight Therapeutics, Inc. (Nasdaq: MPLT), a clinical-stage biopharmaceutical company focused on improving the lives of patients suffering from debilitating central nervous system disorders, today announced topline results from IRIS (ML-004-002), a Phase 2 study of ML-004 in autism spectrum disorder (ASD). The study randomized 161 participants (102 adolescents, 59 adults), with prespecified analyses planned by age group and baseline irritability severity.

Peers Comparison

Key metrics vs top competitors for MapLight Therapeutics, Inc. (MPLT)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MPLT logoMPLTMapLight Therapeutics, Inc.Current
$34.30$1.55B-9.37——-56.19%—
ACNB logoACNBACNB Corporation
$59.93$612.01M16.6528.89%25.81%12.38%—
PTGX logoPTGXProtagonist Therapeutics, Inc.
$121.63$7.82B-59.33-89.41%-648.27%-17.76%—
TERN logoTERNTerns Pharmaceuticals, Inc.
$52.95$4.77B-51.41——-20.02%—
ACLX logoACLXArcellx, Inc.
$115.07$6.73B-28.27-79.35%-1027.25%-55.42%—
NRXP logoNRXPNRx Pharmaceuticals, Inc.
$4.00$69.14M-2.99—-1070.26%——

Compare MPLT vs Peers

MapLight Therapeutics, Inc. (MPLT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACNB

Most directly comparable listed peer for MPLT.

Scale Benchmark

vs BIIB

Larger-name benchmark to compare MPLT against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACNB, PTGX, TERN, ACLX

MPLT SEC Filings & Documents

MapLight Therapeutics, Inc. (MPLT) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 14, 2026·SEC

Material company update

Apr 29, 2026·SEC

Material company update

Mar 26, 2026·SEC

10-K Annual Reports

1
FY 2026

Mar 26, 2026·SEC

10-Q Quarterly Reports

2
FY 2026

May 14, 2026·SEC

FY 2025

Dec 4, 2025·SEC

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MPLT Frequently Asked Questions

MapLight Therapeutics, Inc. (MPLT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is MPLT profitable?

MapLight Therapeutics, Inc. (MPLT) reported a net loss of $199.5M for fiscal year 2025.

Dividend & Returns
What is MPLT's return on equity?

MapLight Therapeutics, Inc. (MPLT) has a return on equity (ROE) of -56.2%. Negative ROE indicates the company is unprofitable.

What is MapLight Therapeutics, Inc.'s free cash flow?

MapLight Therapeutics, Inc. (MPLT) had negative free cash flow of $164.3M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MPLT back in 2022?

Total return calculator · dividends reinvested · 4+ years of data

See returns →