Free cash flow reached a positive 10.6% margin in 2026Q1, supported by a reduction in capital intensity as CapEx/Revenue dropped to 2.7%.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|
| Cash from Operations | 1.29B | 1.13B | -140.63M | -1.16B | -1.5B | -1.3B | -1.28B | -750.27M | -547.72M | 12.75M | -89.51M | -39.84M | -8.69M | 4.07M |
| Operating CF Margin % | - | 21.1% | -3.69% | -47.07% | -105.7% | -110.41% | -415.53% | -175.21% | -276.32% | 5.35% | -8365.7% | -451.94% | -66.7% | 36.54% |
| Operating CF Growth % | 1302.84% | 901.8% | 87.85% | 22.66% | -15.24% | -1.19% | -71.07% | -36.98% | -4395.15% | 114.25% | -124.66% | -358.28% | -313.45% | - |
| Net Income | 513.02M | 286.93M | -644.79M | -881.71M | -2B | -1.41B | -1.6B | -950.58M | -674.03M | -93.3M | -119.22M | -57.1M | -18.55M | -7.89M |
| Depreciation & Amortization | 324.27M | 141.69M | 171.76M | 87.67M | 66.28M | 46.46M | 31.79M | 18.62M | 10.39M | 4.76M | 1.91M | 1.54M | 1.56M | 1.59M |
| Stock-Based Compensation | 1.05B | 510.86M | 441.62M | 367.62M | 303.16M | 240.71M | 183.48M | 134.15M | 87.13M | 42.86M | 10.63M | 10.21M | 6.64M | -24K |
| Deferred Taxes | 9.47M | 9.47M | 25.98M | 689K | 2.06M | -41.09M | -27.81M | -9.23M | -21.95M | -5.84M | 2.93M | 2.15M | -70K | -112K |
| Other Non-Cash Items | -977.96M | -12.77M | 21.96M | -361.19M | 3.31M | -13.11M | -20.98M | 67.6M | 67.96M | 7.08M | 121K | 1.09M | 3.27M | 2.77M |
| Working Capital Changes | 51.2M | 191.4M | -157.17M | -370.54M | 132.39M | -118.34M | 150.58M | -10.83M | -17.21M | 57.2M | 14.12M | 2.26M | -1.54M | 7.75M |
| Change in Receivables | -208.72M | -164.95M | -329.44M | -188.31M | 304.11M | -423.02M | 10.36M | -29.82M | -11.63M | -29.43M | 0 | 0 | 0 | 0 |
| Change in Inventory | -169.41M | -93.17M | -91.5M | -140.95M | -56.69M | -153.33M | -58.91M | -12.31M | -5.31M | -10.93M | 0 | 0 | 0 | 0 |
| Change in Payables | 40.84M | 79.83M | 121.5M | 21.48M | -4.35M | 20.01M | 95.83M | 2.22M | 23.47M | 55.3M | 2.71M | 6.19M | 731K | -768K |
| Cash from Investing | -200.12M | -276.15M | -548.35M | 60M | 1.08B | 640.66M | -3.17B | 554.16M | -637.61M | -356.32M | -221.85M | -58.91M | -33.64M | -250K |
| Capital Expenditures | -418.89M | -185.84M | -492.66M | -561.9M | -469.1M | -314.85M | -229.03M | -158.61M | -140.84M | -58.73M | -23.5M | -5.31M | -654K | -264K |
| CapEx % of Revenue | 7.3% | 3.48% | 12.93% | 22.85% | 33.13% | 26.77% | 74.15% | 37.04% | 71.05% | 24.64% | 2196.45% | 60.28% | 5.02% | 2.37% |
| Acquisitions | 0 | 0 | 0 | 0 | -1.4B | 51.91M | 109.5M | 69M | 70.55M | 19.92M | 0 | 0 | -2.44M | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 225.33M | -81.93M | -39.34M | -36.44M | 1.4B | -51.91M | -109.5M | -69M | -108.85M | -329.86M | 4K | 1K | -30.54M | 14K |
| Cash from Financing | 1.16B | 1.06B | 193.45M | 416.48M | -18.97M | 3.64B | 5.2B | 85.68M | 1.69B | 490.36M | 380.9M | 103.2M | 52.16M | -482K |
| Debt Issued (Net) | 148.4M | 889.71M | 145.08M | 360.77M | -65.94M | 101.53M | 289.6M | 34.68M | 33.58M | 132.76M | 12.05M | 5.85M | 17.85M | 0 |
| Equity Issued (Net) | 43.36M | 196.8M | 0 | 0 | 0 | 3.44B | 4.23B | 0 | 1.63B | 339.12M | 368.88M | 97.28M | 35.42M | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -75K | -80K | 0 |
| Other Financing | 971.21M | -27.06M | 48.37M | 55.71M | 46.96M | 92.76M | 681.21M | 51M | 29.66M | 18.48M | -23K | 77K | -1.1M | -482K |
| Net Change in Cash | 2.32B | 1.97B | -547.24M | -689.05M | -507.85M | 2.99B | 769.23M | -119.94M | 501.11M | 152.09M | 69.64M | 3.97M | 9.97M | 3.3M |
| Free Cash Flow | 846.54M | 941.74M | -669.77M | -1.75B | -1.97B | -1.61B | -1.51B | -908.88M | -688.55M | -45.98M | -113.02M | -45.16M | -9.35M | 3.81M |
| FCF Margin % | 14.75% | 17.63% | -17.58% | -71.32% | -138.83% | -137.18% | -489.68% | -212.25% | -347.37% | -19.29% | -10562.15% | -512.22% | -71.71% | 34.17% |
| FCF Growth % | 452.04% | 240.61% | 61.81% | 10.79% | -21.82% | -6.68% | -66.41% | -32% | -1397.64% | 59.32% | -150.27% | -383.07% | -345.42% | - |
| FCF per Share | 7.31 | 8.30 | -6.36 | -16.80 | -19.06 | -17.39 | -18.12 | -15.13 | -12.42 | -1.10 | -3.64 | -1.43 | -0.18 | 0.72 |
| FCF Conversion (FCF/Net Income) | 1.65x | 3.93x | 0.22x | 1.31x | 0.75x | 0.89x | 0.79x | 0.79x | 0.81x | -0.14x | 0.75x | 0.70x | 0.48x | -0.54x |
| Interest Paid | 23.94M | 0 | 51.17M | 19.75M | 25.17M | 29.97M | 44.13M | 4.32M | 2.21M | 1.26M | 826K | 0 | 0 | 0 |
| Taxes Paid | 67.71M | 0 | 69.43M | 56M | 29.5M | 15.7M | 10.6M | 8.98M | 12K | 29.29M | 25K | 0 | 0 | 0 |
Geopolitical and Regulatory Exposure
According to recent financial disclosures, the relationship between net income and operating cash flow has stabilized, with the OCF/NI ratio reaching 0.89 in 2026Q1, signaling a transition toward more reliable cash generation as the company moves past its initial heavy investment phase.
The historical volatility in the OCF/NI ratio, which previously reached extreme levels, suggests that accounting earnings were heavily distorted by non-cash charges and working capital swings. Investors should monitor whether this convergence persists, as it indicates that the core pharmaceutical business is finally beginning to translate accounting profits into tangible liquidity.
As reported in quarterly filings, BeOne Medicines has successfully pivoted from a cash-burning entity to generating positive free cash flow, with a 10.6% FCF margin in 2026Q1, marking a significant departure from the deep negative margins observed throughout 2024.
This trajectory suggests that the commercial scaling of Brukinsa is effectively offsetting the massive R&D overhead that previously constrained cash flow. The shift to positive FCF appears to be a structural improvement rather than a temporary anomaly, though sustained performance will depend on maintaining this margin expansion.
Based on reported figures, the company's capital intensity has moderated significantly, with CapEx/Revenue dropping to 2.7% in 2026Q1 from a peak of 25.7% in 2024Q1, reflecting a shift from aggressive infrastructure build-out to a more sustainable maintenance and growth-oriented capital expenditure model.
The sharp reduction in capital intensity suggests that the primary manufacturing and R&D facilities are now largely established. This lower burden on cash flow provides management with greater flexibility to allocate capital toward pipeline expansion or strategic initiatives without the need for external financing.
Data from recent statements indicates that working capital remains a volatile component of cash flow, with a significant $189.7 million outflow in 2026Q1, suggesting that inventory management and receivables collection are still subject to the complexities of global pharmaceutical distribution channels.
The erratic nature of these working capital swings warrants further investigation, as they may mask underlying operational inefficiencies or timing differences in global product shipments. Investors should watch for signs of stabilization in these cycles to confirm that the company is effectively managing its supply chain and customer credit.
As highlighted in recent SEC filings, the cash flow statement is significantly impacted by substantial stock-based compensation, which reached $757.1 million in 2025Q4, effectively obscuring the true economic cost of talent retention and diluting the perceived quality of operating cash flow.
While SBC is a non-cash expense, its magnitude suggests that the company's path to profitability is heavily reliant on equity-based incentives rather than purely organic cash generation. This reliance may indicate that the reported cash flow figures are somewhat flattered by the exclusion of these significant compensation-related costs.
Quick answers to the most common questions about buying ONC stock.
BeOne Medicines Ltd. (ONC) generated $1.13B in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
BeOne Medicines Ltd. (ONC) generated $941.7M in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
BeOne Medicines Ltd. (ONC) spent $185.8M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.