| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 3.0M | $13.5M | -0.4% | 4.385% | 0.00% |
| 5 | SYSTEMATIC FINANCIAL MANAGEMENT LP | 2.9M | $12.7M | +15.2% | 4.151% | 0.25% |
| 6 | DIMENSIONAL FUND ADVISORS LP | 2.3M | $10.4M | -17.0% | 3.400% | 0.00% |
| 7 | RENAISSANCE TECHNOLOGIES LLC | 2.0M | $9.0M | -3.3% | 2.927% | 0.01% |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 1.8M | $8.1M | -0.7% | 2.626% | 0.00% |
| 9 | STATE STREET CORP | 1.7M | $7.5M | -1.1% | 2.450% | 0.00% |
| 10 | GAGNON SECURITIES LLC | 1.6M | $7.1M | -7.1% | 2.313% | 1.37% |
| 11 | CANNELL CAPITAL LLC | 1.4M | $6.4M | -28.7% | 2.073% | 4.27% |
| 12 | Gagnon Advisors, LLC | 1.2M | $5.4M | 0.0% | 1.754% | 3.42% |
| 13 | First Eagle Investment Management, LLC | 1.1M | $4.7M | — | 1.544% | 0.00% |
| 14 | Peapod Lane Capital LLC | 994K | $4.4M | -2.4% | 1.444% | 2.99% |
| 15 | WELLS FARGO & COMPANY/MN | 924K | $4.1M | +2.7% | 1.342% | 0.00% |
| 16 | JACOBS LEVY EQUITY MANAGEMENT, INC | 845K | $3.8M | -15.5% | 1.227% | 0.01% |
| 17 | D. E. Shaw & Co., Inc. | 827K | $3.7M | -40.2% | 1.202% | 0.00% |
| 18 | Archon Capital Management LLC | 748K | $3.3M | 0.0% | 1.086% | 1.35% |
| 19 | VANGUARD PORTFOLIO MANAGEMENT LLC | 624K | $2.8M | +5.7% | 0.906% | 0.00% |
| 20 | JPMORGAN CHASE & CO | 589K | $2.7M | +63.4% | 0.856% | 0.00% |
| 21 | NORTHERN TRUST CORP | 587K | $2.6M | -1.3% | 0.853% | 0.00% |
| 22 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 580K | $2.6M | -1.1% | 0.842% | 0.00% |
| 23 | GOLDMAN SACHS GROUP INC | 562K | $2.5M | +36.5% | 0.816% | 0.00% |
| 24 | VANGUARD FIDUCIARY TRUST CO | 458K | $2.0M | +0.7% | 0.665% | 0.00% |
| 25 | TUDOR INVESTMENT CORP ET AL | 401K | $1.8M | +255.5% | 0.582% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in OSUR — a direct measure of their conviction.
| 86.70% |
| 1.99 pp |
| $206M |
| 0.8% |
| Q4 2024 | 188 | +1.6% | 88.69% | +0.37 pp | $208M | 16% |
| Q3 2024 | 185 | — | 88.32% | — | $246M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
26 institutions opened new positions in OSUR during Q2 2026, while 14 fully exited. 108 added to existing positions and 16 trimmed.
OSUR institutional ownership fell by 2.59 percentage points quarter-over-quarter, with a net change of +12 holders.
The top 10 institutions account for 61.1% of all reported 13F value in OSUR, and the top 25 account for 85.1%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.