Praxis Precision Medicines, Inc. (PRAX) Stock Price History
Historical prices from 2020 to 2026
- 1M
- -11.9%
- 3M
- -2.2%
- YTD
- -1.4%
- 1Y
- +557.0%
- 3Y
- +157.7%
- 5Y
- -2.6%
Loading 10-year price history...
PRAX Historical Performance
PRAX Annual Returns
Year-by-year price performance · 2020–2026
- 2020 annual price return
- +97.9%
- 2021 annual price return
- -63.6%
- 2022 annual price return
- -88.3%
- 2023 annual price return
- -42.2%
- 2024 annual price return
- +268.2%
- 2025 annual price return
- +270.6%
- 2026 annual price return
- +17.6%
PRAX Stock Price Trajectory (2020–2026)
As of June 23, 2026, Praxis Precision Medicines, Inc. (PRAX) trades at $303.00, representing a +557.0% return over the past year. The stock has delivered a -12.5% total return over five years (-2.6% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $914.25 on January 8, 2021. From this peak, PRAX has corrected -66.9%, currently trading 23% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers ACAD (-5.8% 1Y), NRIX (+51.0% 1Y), and ARVN (+2.7% 1Y), PRAX has underperformed the peer group average. Compare PRAX vs ACAD →
PRAX Historical Price Data · from 2020
Rows 1–50 of 1,426| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-22 | 292.56 | 305.00 | 285.00 | 303.00 | 630K | +7.33% |
| 2026-06-18 | 280.60 | 289.67 | 274.16 | 282.31 | 601K | +4.56% |
| 2026-06-17 | 259.08 | 277.00 | 259.08 | 270.01 | 371K | +4.96% |
| 2026-06-16 | 264.93 | 274.09 | 255.33 | 257.25 | 404K | -2.76% |
| 2026-06-15 | 270.90 | 274.98 | 262.97 | 264.54 | 431K | -0.75% |
| 2026-06-12 | 247.26 | 269.40 | 247.26 | 266.54 | 422K | +7.48% |
| 2026-06-11 | 241.02 | 252.78 | 239.41 | 247.98 | 413K | +3.04% |
| 2026-06-10 | 249.42 | 257.47 | 238.77 | 240.66 | 380K | -3.86% |
| 2026-06-09 | 260.43 | 266.60 | 244.16 | 250.33 | 426K | -1.15% |
| 2026-06-08 | 258.34 | 266.60 | 247.59 | 253.25 | 546K | -0.30% |
| 2026-06-05 | 269.06 | 269.43 | 252.52 | 254.00 | 564K | -4.15% |
| 2026-06-04 | 275.90 | 279.98 | 263.25 | 264.99 | 964K | -5.00% |
| 2026-06-03 | 259.99 | 279.80 | 258.32 | 278.93 | 676K | +8.08% |
| 2026-06-02 | 305.96 | 321.75 | 256.40 | 258.08 | 1.54M | -23.00% |
| 2026-06-01 | 343.65 | 349.44 | 332.18 | 335.16 | 215K | -4.23% |
| 2026-05-29 | 352.63 | 354.29 | 338.68 | 349.97 | 363K | -0.75% |
| 2026-05-28 | 356.00 | 357.36 | 345.54 | 352.63 | 220K | -1.26% |
| 2026-05-27 | 350.00 | 366.52 | 348.62 | 357.13 | 304K | +1.86% |
| 2026-05-26 | 344.00 | 357.68 | 339.52 | 350.60 | 365K | +2.05% |
| 2026-05-22 | 350.43 | 352.47 | 342.98 | 343.56 | 247K | -2.00% |
| 2026-05-21 | 334.00 | 352.50 | 329.96 | 350.56 | 271K | +4.45% |
| 2026-05-20 | 324.17 | 338.27 | 321.74 | 335.61 | 266K | +4.68% |
| 2026-05-19 | 314.46 | 325.64 | 308.60 | 320.61 | 295K | +0.02% |
| 2026-05-18 | 343.79 | 344.11 | 314.11 | 320.53 | 327K | -6.44% |
| 2026-05-15 | 343.29 | 350.45 | 334.00 | 342.58 | 320K | -0.85% |
| 2026-05-14 | 349.30 | 353.99 | 335.00 | 345.52 | 225K | -0.19% |
| 2026-05-13 | 343.20 | 358.76 | 330.76 | 346.19 | 388K | +0.87% |
| 2026-05-12 | 329.15 | 343.78 | 321.20 | 343.20 | 370K | +3.43% |
| 2026-05-11 | 330.74 | 341.26 | 328.13 | 331.81 | 652K | +0.54% |
| 2026-05-08 | 331.00 | 341.75 | 326.16 | 330.02 | 334K | -0.98% |
| 2026-05-07 | 345.64 | 353.00 | 317.92 | 333.28 | 437K | -1.38% |
| 2026-05-06 | 334.96 | 340.00 | 323.30 | 337.95 | 297K | +1.40% |
| 2026-05-05 | 339.89 | 344.99 | 324.32 | 333.30 | 210K | -1.28% |
| 2026-05-04 | 322.43 | 339.30 | 322.43 | 337.61 | 262K | +4.14% |
| 2026-05-01 | 318.00 | 335.00 | 310.00 | 324.20 | 324K | +1.68% |
| 2026-04-30 | 327.64 | 330.19 | 316.60 | 318.83 | 467K | -1.35% |
| 2026-04-29 | 319.00 | 325.08 | 315.45 | 323.19 | 362K | +0.39% |
| 2026-04-28 | 333.79 | 349.01 | 319.40 | 321.92 | 413K | -2.74% |
| 2026-04-27 | 344.16 | 348.30 | 327.21 | 330.99 | 354K | -4.01% |
| 2026-04-24 | 330.50 | 345.21 | 322.02 | 344.82 | 328K | +4.62% |
| 2026-04-23 | 339.69 | 344.00 | 327.54 | 329.60 | 322K | -2.28% |
| 2026-04-22 | 344.20 | 348.98 | 334.18 | 337.29 | 176K | -1.04% |
| 2026-04-21 | 340.64 | 344.74 | 332.11 | 340.84 | 348K | -0.51% |
| 2026-04-20 | 342.68 | 349.49 | 339.99 | 342.57 | 327K | +0.02% |
| 2026-04-17 | 326.26 | 346.35 | 324.87 | 342.50 | 403K | +6.90% |
| 2026-04-16 | 336.02 | 340.42 | 314.14 | 320.39 | 474K | -5.75% |
| 2026-04-15 | 348.04 | 350.00 | 330.00 | 339.93 | 490K | -1.07% |
| 2026-04-14 | 327.50 | 352.56 | 325.95 | 343.60 | 684K | +8.39% |
| 2026-04-13 | 320.00 | 332.99 | 316.50 | 317.00 | 267K | +0.27% |
| 2026-04-10 | 325.12 | 326.93 | 312.89 | 316.14 | 252K | -1.28% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
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Peer Comparison
Compare growth, multiples, and margins vs sector.
PRAX — Frequently Asked Questions
Quick answers to the most common questions about buying PRAX stock.
How has PRAX stock performed recently?
PRAX returned +557.0% over the past year, beating its 5-year annualized CAGR of -2.6%. The stock trades above its 200-day moving average, confirming the uptrend.
What is PRAX's all-time high price?
Praxis Precision Medicines, Inc. reached $914.25 on 2021-01-08. The 52-week high is $366.52. Current 1-year return of +557.0% places the stock closer to historical peaks.
Where can I download PRAX historical price data?
This page provides PRAX daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2020-2026, downloadable in CSV format.