Prelude Therapeutics Incorporated (PRLD) Earnings History
Net Loss8 years of earnings data (2018–2025) · Currently unprofitable on a TTM basis
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Prelude Therapeutics Incorporated (PRLD) Earnings Overview
As of June 23, 2026, Prelude Therapeutics Incorporated (PRLD) reported trailing twelve-month net income of -$78M, reflecting +23.2% year-over-year growth. The company earned $-0.94 per diluted share over the past four quarters, with a net profit margin of -819.6%.
Looking at the long-term picture, PRLD's historical earnings data spans multiple years. The company achieved its highest annual net income of -$15M in fiscal 2018.
Prelude Therapeutics Incorporated is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →
Compared to peers including RVMD (-$1.37B net income), KYMR (-$315M net income, -794.4% margin), ARVN (-$221M net income, -30.8% margin), PRLD has comparable earnings metrics. Compare PRLD vs RVMD →
PRLD Earnings vs Peers
Earnings metrics vs comparable public companies
PRLD Historical Earnings Data (2018–2025)
8 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | -$99M | +21.8% | -$105M | $-1.29 | -819.6% | -861.3% |
| 2024 | -$127M | -4.4% | -$140M | $-1.68 | -1816.8% | -1995.9% |
| 2023 | -$122M | -5.5% | -$132M | $-2.02 | - | - |
| 2022 | -$115M | -3.4% | -$124M | $-2.27 | - | - |
| 2021 | -$112M | -96.2% | -$114M | $-2.33 | - | - |
| 2020 | -$57M | -106.5% | -$59M | $-1.30 | - | - |
| 2019 | -$28M | -87.8% | -$28M | $-0.85 | - | - |
| 2018 | -$15M | - | -$15M | $-9.31 | - | - |
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PRLD — Frequently Asked Questions
Quick answers to the most common questions about buying PRLD stock.
What is PRLD earnings per share (EPS)?
PRLD trailing twelve-month (TTM) diluted EPS is $-0.94, reflecting +23.2% year-over-year growth. The 5-year EPS CAGR is N/A. Complete EPS history from 2018 to 2025 is available in the table on this page.
What is Prelude Therapeutics Incorporated's net income?
Prelude Therapeutics Incorporated (PRLD) trailing twelve-month net income is $-78M as of 2025. Earnings grew +23.2% year-over-year.
Is PRLD profitable?
PRLD is not currently profitable on a TTM basis, reporting a net loss of $-78M. Net margin is -819.6%. Investors should monitor for a return to profitability.
What is PRLD's earnings growth rate?
PRLD compound annual EPS growth rates (CAGR): 1-Year: N/A, 3-Year: N/A, 5-Year: N/A, 10-Year: N/A. These figures measure the annualised rate of diluted EPS growth over each period, based on data from 2018 to 2025.
What are PRLD's profit margins?
Prelude Therapeutics Incorporated net profit margin is -819.6%, operating margin is -861.3%, and gross margin is +85.9%. Below-average margins reflect competitive or cost pressures. Return on Equity is -99.5%.
Is PRLD growing earnings?
Yes, PRLD earnings are accelerating — EPS growth of +23.2% exceeds the 5-year CAGR of N/A. TTM net income reached $-78M. Earnings momentum is strengthening.
What was PRLD's best earnings year?
Prelude Therapeutics Incorporated's highest annual net income on record is $-15M, achieved in fiscal year 2018. Earnings history on this page spans 2018 to 2025 and includes all annual and quarterly figures.
What were PRLD's earnings last quarter?
PRLD's most recent reported quarter was Q1 2026. Net income was $-10M with diluted EPS of $-0.13. For a full breakdown of all quarters, see the quarterly earnings table on this page.