Prelude Therapeutics Incorporated (PRLD) Stock Price History
Historical prices from 2020 to 2026
- 1M
- -0.5%
- 3M
- +38.5%
- YTD
- +58.2%
- 1Y
- +401.7%
- 3Y
- -6.5%
- 5Y
- -32.6%
Loading 10-year price history...
PRLD Historical Performance
PRLD Annual Returns
Year-by-year price performance · 2020–2026
- 2020 annual price return
- +173.1%
- 2021 annual price return
- -81.5%
- 2022 annual price return
- -54.3%
- 2023 annual price return
- -14.9%
- 2024 annual price return
- -68.8%
- 2025 annual price return
- +132.0%
- 2026 annual price return
- +1.1%
PRLD Stock Price Trajectory (2020–2026)
As of June 22, 2026, Prelude Therapeutics Incorporated (PRLD) trades at $4.32, representing a +401.7% return over the past year. The stock has delivered a -86.1% total return over five years (-32.6% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $95.38 on February 10, 2021. From this peak, PRLD has corrected -95.5%, currently trading 63% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers RVMD (+308.2% 1Y), KYMR (+94.7% 1Y), and ARVN (+2.7% 1Y), PRLD has outperformed the peer group average. Compare PRLD vs RVMD →
PRLD Historical Price Data · from 2020
Rows 1–50 of 1,440| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-18 | 4.30 | 4.64 | 4.16 | 4.32 | 859K | -0.46% |
| 2026-06-17 | 4.29 | 4.43 | 4.07 | 4.34 | 313K | +3.33% |
| 2026-06-16 | 4.32 | 4.48 | 4.09 | 4.20 | 349K | -5.83% |
| 2026-06-15 | 4.60 | 4.69 | 4.42 | 4.46 | 315K | -0.67% |
| 2026-06-12 | 4.03 | 4.52 | 4.00 | 4.49 | 309K | +9.25% |
| 2026-06-11 | 3.95 | 4.13 | 3.92 | 4.11 | 205K | +4.05% |
| 2026-06-10 | 3.98 | 4.11 | 3.88 | 3.95 | 192K | +0.25% |
| 2026-06-09 | 3.87 | 4.02 | 3.77 | 3.94 | 233K | +2.60% |
| 2026-06-08 | 3.86 | 4.00 | 3.77 | 3.84 | 281K | +0.79% |
| 2026-06-05 | 4.00 | 4.00 | 3.73 | 3.81 | 220K | -6.62% |
| 2026-06-04 | 3.62 | 4.19 | 3.61 | 4.08 | 391K | +11.48% |
| 2026-06-03 | 3.49 | 3.72 | 3.40 | 3.66 | 375K | +4.57% |
| 2026-06-02 | 3.76 | 3.76 | 3.47 | 3.50 | 374K | -8.38% |
| 2026-06-01 | 3.88 | 4.00 | 3.81 | 3.82 | 222K | -2.55% |
| 2026-05-29 | 3.93 | 3.98 | 3.76 | 3.92 | 275K | -0.25% |
| 2026-05-28 | 4.13 | 4.13 | 3.80 | 3.93 | 372K | -5.53% |
| 2026-05-27 | 4.17 | 4.32 | 4.10 | 4.16 | 151K | +1.71% |
| 2026-05-26 | 4.14 | 4.31 | 4.03 | 4.09 | 310K | -4.22% |
| 2026-05-22 | 4.37 | 4.52 | 4.17 | 4.27 | 240K | -1.39% |
| 2026-05-21 | 4.40 | 4.53 | 4.31 | 4.33 | 213K | -3.78% |
| 2026-05-20 | 4.30 | 4.54 | 4.12 | 4.50 | 367K | +5.39% |
| 2026-05-19 | 4.27 | 4.47 | 3.95 | 4.27 | 402K | -1.61% |
| 2026-05-18 | 4.44 | 4.74 | 4.31 | 4.34 | 463K | -3.13% |
| 2026-05-15 | 4.26 | 4.60 | 4.11 | 4.48 | 470K | +0.22% |
| 2026-05-14 | 4.50 | 4.67 | 4.40 | 4.47 | 261K | -4.08% |
| 2026-05-13 | 4.57 | 4.81 | 4.42 | 4.66 | 392K | +0.43% |
| 2026-05-12 | 4.75 | 4.97 | 4.55 | 4.64 | 306K | -3.33% |
| 2026-05-11 | 4.80 | 5.14 | 4.75 | 4.80 | 343K | -1.23% |
| 2026-05-08 | 5.29 | 5.32 | 4.80 | 4.86 | 385K | -5.63% |
| 2026-05-07 | 4.88 | 5.31 | 4.65 | 5.15 | 545K | +6.40% |
| 2026-05-06 | 4.78 | 5.04 | 4.32 | 4.84 | 697K | +3.64% |
| 2026-05-05 | 4.85 | 5.13 | 4.65 | 4.67 | 405K | -1.48% |
| 2026-05-04 | 4.82 | 4.92 | 4.51 | 4.74 | 719K | +0.85% |
| 2026-05-01 | 5.18 | 5.22 | 4.50 | 4.70 | 1.10M | -10.13% |
| 2026-04-30 | 4.51 | 5.23 | 4.27 | 5.23 | 575K | +22.48% |
| 2026-04-29 | 4.26 | 4.37 | 4.04 | 4.27 | 453K | -2.73% |
| 2026-04-28 | 4.53 | 4.75 | 4.17 | 4.39 | 376K | -2.88% |
| 2026-04-27 | 4.92 | 5.08 | 4.43 | 4.52 | 585K | -3.83% |
| 2026-04-24 | 4.88 | 4.88 | 4.51 | 4.70 | 858K | +6.82% |
| 2026-04-23 | 4.33 | 4.42 | 3.89 | 4.40 | 689K | +2.09% |
| 2026-04-22 | 4.66 | 4.73 | 4.28 | 4.31 | 314K | -6.71% |
| 2026-04-21 | 4.69 | 4.99 | 4.48 | 4.62 | 377K | +2.44% |
| 2026-04-20 | 5.21 | 5.50 | 4.50 | 4.51 | 957K | +1.58% |
| 2026-04-17 | 4.50 | 4.50 | 4.10 | 4.44 | 351K | +0.23% |
| 2026-04-16 | 5.50 | 5.51 | 4.21 | 4.43 | 829K | -19.75% |
| 2026-04-15 | 4.34 | 5.54 | 4.26 | 5.52 | 970K | +25.45% |
| 2026-04-14 | 4.36 | 4.45 | 4.27 | 4.40 | 197K | +0.69% |
| 2026-04-13 | 4.17 | 4.48 | 4.05 | 4.37 | 176K | +7.11% |
| 2026-04-10 | 4.43 | 4.62 | 4.08 | 4.08 | 194K | -7.27% |
| 2026-04-09 | 4.20 | 4.45 | 3.83 | 4.40 | 233K | +4.27% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
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Peer Comparison
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PRLD — Frequently Asked Questions
Quick answers to the most common questions about buying PRLD stock.
How has PRLD stock performed recently?
PRLD returned +401.7% over the past year, beating its 5-year annualized CAGR of -32.6%. The stock trades above its 200-day moving average, confirming the uptrend.
What is PRLD's all-time high price?
Prelude Therapeutics Incorporated reached $95.38 on 2021-02-10. The 52-week high is $5.54. Current 1-year return of +401.7% places the stock closer to historical peaks.
Where can I download PRLD historical price data?
This page provides PRLD daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2020-2026, downloadable in CSV format.