Prelude Therapeutics Incorporated (PRLD) Stock Price History
Historical prices from 2020 to 2026
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PRLD Historical Performance
Short-Term Returns
PRLD Stock Price Trajectory (2020–2026)
As of May 8, 2026, Prelude Therapeutics Incorporated (PRLD) trades at $5.15, representing a +573.8% return over the past year. The stock has delivered a -87.6% total return over five years (-34.2% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $95.38 on February 10, 2021. From this peak, PRLD has corrected -94.6%, currently trading 136% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers RVMD (+278.4% 1Y), KYMR (+190.7% 1Y), and ARVN (+52.8% 1Y), PRLD has outperformed the peer group average. Compare PRLD vs RVMD →
PRLD Historical Price Data (2025–2026)
Showing 30 of 1,411 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-07 | 4.88 | 5.31 | 4.65 | 5.15 | 545K | +6.40% |
| 2026-05-06 | 4.78 | 5.04 | 4.32 | 4.84 | 697K | +3.64% |
| 2026-05-05 | 4.85 | 5.13 | 4.65 | 4.67 | 405K | -1.48% |
| 2026-05-04 | 4.82 | 4.92 | 4.51 | 4.74 | 719K | +0.85% |
| 2026-05-01 | 5.18 | 5.22 | 4.50 | 4.70 | 1.10M | -10.13% |
| 2026-04-30 | 4.51 | 5.23 | 4.27 | 5.23 | 575K | +22.48% |
| 2026-04-29 | 4.26 | 4.37 | 4.04 | 4.27 | 453K | -2.73% |
| 2026-04-28 | 4.53 | 4.75 | 4.17 | 4.39 | 376K | -2.88% |
| 2026-04-27 | 4.92 | 5.08 | 4.43 | 4.52 | 585K | -3.83% |
| 2026-04-24 | 4.88 | 4.88 | 4.51 | 4.70 | 858K | +6.82% |
| 2026-04-23 | 4.33 | 4.42 | 3.89 | 4.40 | 689K | +2.09% |
| 2026-04-22 | 4.66 | 4.73 | 4.28 | 4.31 | 314K | -6.71% |
| 2026-04-21 | 4.69 | 4.99 | 4.48 | 4.62 | 377K | +2.44% |
| 2026-04-20 | 5.21 | 5.50 | 4.50 | 4.51 | 957K | +1.58% |
| 2026-04-17 | 4.50 | 4.50 | 4.10 | 4.44 | 351K | +0.23% |
| 2026-04-16 | 5.50 | 5.51 | 4.21 | 4.43 | 829K | -19.75% |
| 2026-04-15 | 4.34 | 5.54 | 4.26 | 5.52 | 970K | +25.45% |
| 2026-04-14 | 4.36 | 4.45 | 4.27 | 4.40 | 197K | +0.69% |
| 2026-04-13 | 4.17 | 4.48 | 4.05 | 4.37 | 176K | +7.11% |
| 2026-04-10 | 4.43 | 4.62 | 4.08 | 4.08 | 194K | -7.27% |
| 2026-04-09 | 4.20 | 4.45 | 3.83 | 4.40 | 233K | +4.27% |
| 2026-04-08 | 4.57 | 4.82 | 4.20 | 4.22 | 390K | -4.09% |
| 2026-04-07 | 3.68 | 4.49 | 3.68 | 4.40 | 687K | +19.57% |
| 2026-04-06 | 3.65 | 3.90 | 3.58 | 3.68 | 384K | +6.36% |
| 2026-04-02 | 3.53 | 3.65 | 3.43 | 3.46 | 106K | +0.29% |
| 2026-04-01 | 3.45 | 3.69 | 3.44 | 3.45 | 140K | +0.88% |
| 2026-03-31 | 3.14 | 3.58 | 3.14 | 3.42 | 188K | +11.40% |
| 2026-03-30 | 3.10 | 3.21 | 3.01 | 3.07 | 176K | +0.66% |
| 2026-03-27 | 3.23 | 3.32 | 3.01 | 3.05 | 119K | -5.86% |
| 2026-03-26 | 3.20 | 3.31 | 3.14 | 3.24 | 91K | -0.61% |
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Start ComparisonPRLD — Frequently Asked Questions
Quick answers to the most common questions about buying PRLD stock.
How has PRLD stock performed recently?
PRLD returned +573.8% over the past year, beating its 5-year annualized CAGR of -34.2%. The stock trades above its 200-day moving average, confirming the uptrend.
What is PRLD's all-time high price?
Prelude Therapeutics Incorporated reached $95.38 on 2021-02-10. The 52-week high is $5.54. Current 1-year return of +573.8% places the stock closer to historical peaks.
Where can I download PRLD historical price data?
This page provides PRLD daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2020-2026, downloadable in CSV format.