Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in PSTV held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | VANGUARD CAPITAL MANAGEMENT LLC | 2.4M | $396K | β | 100.310% | 0.00% |
| 2 | GEODE CAPITAL MANAGEMENT, LLC | 2.0M | $328K | +43.7% | 83.332% | 0.00% |
| 3 | BlackRock, Inc. | 1.8M | $289K | 0.0% | 73.416% | 0.00% |
| 4 | VANGUARD FIDUCIARY TRUST CO | 1.2M | $190K | β | 48.098% | 0.00% |
| 5 | STATE STREET CORP | 469K | $76K | 0.0% | 19.379% | 0.00% |
| 6 | NORTHERN TRUST CORP | 293K | $48K | 0.0% | 12.122% | 0.00% |
| 7 | MILLENNIUM MANAGEMENT LLC | 272K | $44K | β | 11.225% | 0.00% |
| 8 | TWO SIGMA SECURITIES, LLC | 143K | $23K | +155.6% | 5.902% | 0.00% |
| 9 | XTX Topco Ltd | 116K | $19K | -53.3% | 4.795% | 0.00% |
| 10 | CITIGROUP INC | 93K | $15K | +91.9% | 3.844% | 0.00% |
| 11 | UBS Group AG | 88K | $14K | -90.0% | 3.631% | 0.00% |
| 12 | MERCER GLOBAL ADVISORS INC /ADV | 64K | $10K | β | 2.650% | 0.00% |
| 13 | Vanguard Global Advisers, LLC | 57K | $9K | β | 2.359% | 0.00% |
| 14 | Miller Financial Services LLC | 50K | $8K | β | 2.067% | 0.01% |
| 15 | Ashton Thomas Private Wealth, LLC | 33K | $5K | +32.1% | 1.360% | 0.00% |
| 16 | DAGCO, INC. | 26K | $4K | 0.0% | 1.070% | 0.00% |
| 17 | Kestra Advisory Services, LLC | 26K | $4K | 0.0% | 1.066% | 0.00% |
| 18 | Forum Financial Management, LP | 10K | $2K | β | 0.413% | 0.00% |
| 19 | ADVISOR GROUP HOLDINGS, INC. | 133 | $21 | 0.0% | 0.006% | 0.00% |
| 20 | WELLS FARGO & COMPANY/MN | 53 | $9 | 0.0% | 0.002% | 0.00% |
| 21 | Sound Income Strategies, LLC | 28 | $4 | 0.0% | 0.001% | 0.00% |
| 22 | Cambridge Investment Research Advisors, Inc. | 13K | $2 | 0.0% | 0.556% | 0.00% |
| 23 | DANSKE BANK A/S | 1 | $0 | 0.0% | 0.000% | 0.00% |
| 24 | BARCLAYS PLC | 2 | $0 | 0.0% | 0.000% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in PSTV β a direct measure of their conviction.
Filings activity in PSTV during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new PSTV position in Q1 2026
Institutions that fully closed their PSTV position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 24 | 11% | 12.25% | 34.42 pp | $1M | 74% |
| Q4 2025 | 27 | +17% | 46.67% | +17.31 pp | $6M | +59% |
| Q3 2025 | 23 | +21% | 29.36% | +28.27 pp | $4M | +2604% |
| Q2 2025 | 19 | +12% | 1.09% | 0.84 pp | $0M | 44% |
| Q1 2025 | 17 | +55% | 1.93% | 4.50 pp | $0M | 70% |
| Q4 2024 | 11 | +0.0% | 6.43% | 1.66 pp | $1M | 20% |
| Q3 2024 | 11 | 15% | 8.09% | 0.18 pp | $1M | 2.1% |
| Q2 2024 | 13 | β | 8.27% | β | $1M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying PSTV stock.
Based on Q1 2026 13F filings, institutional ownership of Plus Therapeutics, Inc. stands at 12.3%, held across 24 reporting institutions.
VANGUARD CAPITAL MANAGEMENT LLC is the largest reported institutional holder of PSTV, with approximately 2,427,098 shares worth $0.00B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of PSTV, including MILLENNIUM MANAGEMENT LLC, TWO SIGMA SECURITIES, LLC.
Our composite Smart Money Score for PSTV is 38 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
7 institutions opened new positions in PSTV during Q1 2026, while 10 fully exited. 0 added to existing positions and 15 trimmed.
PSTV institutional ownership fell by 34.42 percentage points quarter-over-quarter, with a net change of -3 holders.
The top 10 institutions account for 96.1% of all reported 13F value in PSTV, and the top 25 account for 100.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Plus Therapeutics, Inc. (PSTV) Institutional Ownership