Latest Ratios: P/E Ratio -11.2x · EV/EBITDA N/A · ROE -28.2%. (2022–2025 historical series)
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| Market Cap | $1.5B | $1.4B | $368M | — | — |
| Enterprise Value | $1.5B | $1.4B | $313M | — | — |
| P/E Ratio → | -11.25 | — | — | — | — |
| P/S Ratio | — | — | — | — | — |
| P/B Ratio | 3.12 | 2.94 | 1.20 | — | — |
| P/FCF | — | — | — | — | — |
| P/OCF | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| EV / Revenue | — | — | — | — | — |
| EV / EBITDA | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — |
| EV / FCF | — | — | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| Gross Margin | — | — | — | — | — |
| Operating Margin | — | — | — | — | — |
| Net Profit Margin | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| ROE | -28.2% | -28.2% | -56.0% | — | -54.6% |
| ROA | -26.9% | -26.9% | -33.3% | -37.2% | -33.7% |
| ROIC | -27.1% | -27.1% | -79.6% | — | — |
| ROCE | -31.3% | -31.3% | -36.7% | -41.0% | -34.6% |
Solvency and debt-coverage ratios — lower is generally safer
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| Debt / Equity | 0.02 | 0.02 | 0.00 | — | 0.53 |
| Debt / EBITDA | — | — | — | — | — |
| Net Debt / Equity | — | -0.08 | -0.18 | — | -1.06 |
| Net Debt / EBITDA | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — |
| Interest Coverage | — | — | — | — | -36.38 |
Net cash position: cash ($53M) exceeds total debt ($11M)
Short-term solvency ratios and asset-utilisation metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| Current Ratio | 26.17 | 26.17 | 35.34 | 17.14 | 18.80 |
| Quick Ratio | 26.17 | 26.17 | 35.34 | 17.14 | 18.80 |
| Cash Ratio | 25.75 | 25.75 | 34.82 | 16.75 | 18.74 |
| Asset Turnover | — | — | — | — | — |
| Inventory Turnover | — | — | — | — | — |
| Days Sales Outstanding | — | — | — | — | — |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 |
|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — |
| FCF Yield | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | — | — |
| Shares Outstanding | — | $47M | $21M | $18M | $20M |
Includes 30+ ratios · 4 years · Updated daily
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DCF models, multiple analysis, and analyst estimates.
10-year return with dividends reinvested.
Compare growth, multiples, and margins vs sector.
Quick answers to the most common questions about buying RAPP stock.
Rapport Therapeutics, Inc. Common Stock's current P/E ratio is -11.2x. This places it at the 50th percentile of its historical range.
Rapport Therapeutics, Inc. Common Stock's return on equity (ROE) is -28.2%. The historical average is -46.3%.
Based on historical data, Rapport Therapeutics, Inc. Common Stock is trading at a P/E of -11.2x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
Key Metrics
Top Statement Risk
Dilution from equity funding
Metrics are mathematically derived from official filings.
Cash Buffer Shrinks as Burn Accelerates
Current ratio remains high at 15.72, but cash dropped 75% from $251.4M in 2025Q3 to $63.6M in 2026Q2, implying roughly one quarter of runway against quarterly operating losses of $60.8M, as per quarterly filings.
The current ratio of 15.72 in 2026Q2, while superficially robust, is misleading because the vast majority of current assets are cash and marketable securities that are being consumed rapidly. With quarterly operating losses exceeding $60M, the liquidity position is adequate only in the very near term, and the company will likely need to raise additional capital within the next two quarters to sustain operations through pivotal trial milestones. Investors should monitor the pace of cash consumption relative to trial enrollment milestones, as any delay in data readouts would compress the runway further.
Minimal Leverage Masks Equity Dependence
Debt-to-equity stands at 0.02 with total debt of $10.1M, indicating negligible reliance on debt financing, but the company remains entirely dependent on equity funding to sustain its pre-revenue operations, as reported in the latest balance sheet.
The near-zero leverage is a double-edged sword: it eliminates solvency risk and interest burden, but it also signals that the company has no debt cushion to bridge funding gaps. With negative retained earnings of -$311.7M and no revenue, the balance sheet is essentially a function of IPO proceeds and subsequent equity raises. The low D/E ratio may appear conservative, but it reflects a structural reliance on dilutive financing rather than prudent capital structure management. As pivotal trial costs escalate, the company will likely need to access equity markets again, which could dilute existing shareholders.
Asset-Light Model with Minimal Tangible Base
Asset turnover is negligible at 0.04 in 2026Q1, reflecting a pre-revenue model where assets are primarily cash and R&D investments, with net PPE of only $11.1M, as per the latest balance sheet.
The efficiency ratios are largely uninformative in the traditional sense because the company has no product sales and its asset base is dominated by cash and intangible R&D value. The low asset turnover is expected for a clinical-stage biotech, but it underscores that the company's value creation is tied to clinical trial execution, not operational efficiency. Working capital metrics like DSO, DIO, and DPO are not reported, which is consistent with a company that has minimal receivables or inventory. The key efficiency metric to watch is the burn-to-milestone ratio, which measures how efficiently cash is converted into clinical data.
Pre-Revenue Losses Deepen with Pivotal Trials
Operating margin deteriorated to -121.1% in 2026Q1, with R&D expenses consuming 84% of total operating expenses, reflecting the ramp into pivotal FOCUS trials, as reported in financial statements.
Profitability metrics are deeply negative and worsening, with net margin at -99.3% in 2026Q1 and ROE at -12.7% in 2026Q2. The losses are driven by escalating R&D costs, which rose 311% over ten quarters to $51.4M in 2026Q2. While stock-based compensation cushions reported losses, the cash burn is real and accelerating. The company is in a capital-consumption phase where profitability is not expected until a product is commercialized, likely years away. Investors should focus on the trajectory of R&D spend relative to clinical milestones rather than traditional margin analysis.
Negative Returns Reflect Pre-Revenue Stage
ROIC has been consistently negative, ranging from -6.3% to -26.8% over the last ten quarters, with the latest at -11.8% in 2026Q2, indicating that the company is not yet generating returns on invested capital, as per quarterly data.
The negative ROIC is expected for a clinical-stage biotech, but the trend is concerning because the magnitude of losses is growing faster than the capital base. The 2024Q2 ROIC of -26.8% was an outlier, likely due to a smaller equity base, while recent quarters show a more stable but still deeply negative return. The company is effectively destroying capital as it invests in R&D, but this is the intended business model. The key question is whether the RAP platform will eventually generate returns that justify the cumulative investment. Investors should compare the burn rate to the potential market opportunity for RAP-219 in focal epilepsy.
Misapplied Metric: Current Ratio
The current ratio of 15.72 is commonly misapplied to RAPP as a sign of financial strength, but it obscures the fact that cash of $63.6M against quarterly operating losses of $60.8M implies a runway of roughly one quarter, as per reported figures.
For a pre-revenue biotech, the current ratio is a misleading indicator of liquidity because it treats cash and marketable securities as if they are available to cover all current liabilities, but the real constraint is the cash burn rate. A high current ratio can coexist with imminent insolvency if the burn rate is high. The more relevant metric is the cash runway, which is calculated by dividing cash by quarterly operating cash burn. In RAPP's case, the runway is dangerously short, and the current ratio masks this urgency. Investors should use cash runway and burn multiple instead of current ratio when assessing liquidity risk for clinical-stage companies.