Free cash flow margins exhibit high sensitivity to operational cycles, fluctuating from a low of 4.0% in 2024Q2 to a peak of 42.9% in 2024Q1.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 | Dec'98 | Dec'97 | Dec'96 |
|---|
| Cash from Operations | 5.01B | 4.98B | 4.42B | 4.59B | 5.01B | 7.08B | 2.62B | 2.43B | 2.2B | 1.31B | 1.49B | 1.33B | 752.43M | 588.6M | -74.61M | -141.68M | 96.34M | -72.23M | -89.09M | 27.37M | 23.07M | -30.3M | -16.91M | -6.13M | -110.52M | -57.32M | -27.91M | -13.8M | -10.2M | -6.1M | -20.3M |
| Operating CF Margin % | - | 34.71% | 31.13% | 35.02% | 41.2% | 44.06% | 30.81% | 37.06% | 32.71% | 22.26% | 30.57% | 32.43% | 26.69% | 27.97% | -5.41% | -31.78% | 20.99% | -19.04% | -37.36% | 21.89% | 36.37% | -45.77% | -9.72% | -10.67% | -502.65% | -260.87% | -47.08% | -40% | -26.7% | -18.43% | -84.23% |
| Operating CF Growth % | 244.58% | 12.63% | -3.78% | -8.39% | -29.18% | 170.47% | 7.74% | 10.7% | 67.94% | -12.03% | 11.66% | 76.86% | 27.84% | 888.84% | 47.34% | -247.06% | 233.38% | 18.92% | -425.46% | 18.62% | 176.17% | -79.17% | -175.71% | 94.45% | -92.82% | -105.37% | -102.25% | -35.29% | -67.21% | 69.95% | -11.54% |
| Net Income | 4.42B | 4.5B | 4.41B | 3.95B | 4.34B | 8.08B | 3.51B | 2.12B | 2.44B | 1.2B | 895.52M | 636.06M | 348.07M | 424.36M | 750.27M | -221.76M | -104.47M | -67.83M | -82.71M | -105.6M | -102.34M | -95.45M | 41.7M | -107.46M | -124.38M | -76.18M | -23.21M | -23.1M | -8.6M | -11.6M | -32.4M |
| Depreciation & Amortization | 540M | 543.7M | 482.9M | 421M | 341.4M | 286.2M | 235.9M | 210.3M | 148.2M | 145.47M | 104.75M | 74.91M | 52.69M | 41.2M | 36.94M | 31.08M | 19.69M | 14.25M | 11.29M | 11.49M | 14.59M | 15.5M | 15.36M | 12.94M | 8.45M | 6.08M | 4.42M | 3.4M | 3M | 4.4M | 6.1M |
| Stock-Based Compensation | 995.4M | 993.7M | 982.8M | 885M | 725M | 601.7M | 432M | 464.3M | 427.4M | 507.28M | 559.88M | 459.05M | 307.24M | 198.4M | 94.16M | 56.09M | 39.9M | 31.26M | 32.52M | 28.07M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | -742.3M | -785.4M | -757.3M | -837.8M | -746.4M | -147.1M | 75.6M | -130.6M | -140M | 318.81M | -360.08M | -121.62M | -66.6M | 63.6M | -340.16M | 0 | 0 | -56K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -529.4M | -810.6M | -82.2M | 266.3M | 599.8M | 181.7M | -135M | -29.3M | 12.1M | 63.57M | 57.64M | 52.56M | 19.63M | 45.34M | 56.97M | 10.37M | 293K | -382K | 2.25M | 5.94M | 17.86M | 21.86M | -15.23M | 4.06M | 1.82M | 1.77M | 6.14M | 4.7M | 2.8M | 3.7M | 14.5M |
| Working Capital Changes | 325.6M | 532.6M | -618.3M | -94.1M | -243.3M | -1.92B | -1.5B | -200.5M | -697M | -926.53M | 228.19M | 229.83M | 20.24M | -190.67M | -672.8M | -17.46M | 140.94M | -49.47M | -52.43M | 87.47M | 92.96M | 27.79M | -58.74M | 84.33M | 3.58M | 11.02M | -15.25M | 1.2M | -7.4M | -2.6M | -8.5M |
| Change in Receivables | -158.5M | 498.1M | -554M | -338.8M | 707.8M | -1.93B | -1.36B | -473.1M | -268.9M | -362.72M | -143.83M | -491.42M | -62.43M | -198.66M | -590.09M | -21.12M | -27.54M | -30.36M | -16.89M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | -96.4M | -275.3M | -619.7M | -271.7M | -696.5M | -494.3M | -529.4M | -335.5M | -387.9M | -314.19M | -149.78M | -111.83M | -60.9M | -47.96M | -52.62M | 0 | 0 | -4.57M | 0 | 0 | 3.59M | 1.25M | 6.91M | -1.05M | -1.73M | -941K | 4.05M | -4M | 0 | 0 | 0 |
| Change in Payables | 1.06B | 736.8M | 735.1M | 598.6M | -138.4M | 866.1M | 118.9M | 444.5M | 210M | -23.19M | 253.98M | 303.66M | 162.24M | 136.68M | 10.98M | 0 | 0 | 12.96M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | -1.71B | -629.1M | -2.47B | -3.19B | -3.78B | -5.38B | -70.6M | -2.03B | -1.46B | -1.01B | -1.05B | -907.6M | -420.78M | -355.45M | -81.07M | 128.47M | -434.15M | 146K | 30.82M | -85.72M | -155.1M | 115.49M | -4.58M | -63.84M | -58.52M | -75.39M | -57.68M | 17.5M | 2.4M | -38.9M | -44.3M |
| Capital Expenditures | -1.17B | -1.21B | -755.9M | -926.4M | -590.1M | -551.9M | -614.6M | -429.6M | -383.1M | -272.6M | -511.9M | -677.93M | -333.01M | -156.32M | -49.34M | -57.22M | -99.69M | -97.32M | -34.86M | -18.45M | -2.81M | -4.96M | -6.17M | -29.66M | -34.37M | -8.22M | -6.5M | -5.7M | -3M | -2.1M | -8.6M |
| CapEx % of Revenue | 7.86% | 8.46% | 5.32% | 7.06% | 4.85% | 3.43% | 7.23% | 6.55% | 5.71% | 4.64% | 10.53% | 16.52% | 11.81% | 7.43% | 3.58% | 12.83% | 21.72% | 25.66% | 14.62% | 14.75% | 4.43% | 7.5% | 3.55% | 51.58% | 156.31% | 37.42% | 10.96% | 16.52% | 7.85% | 6.34% | 35.68% |
| Acquisitions | -3.3M | -3.3M | -16.5M | -54.9M | -230.3M | 551.9M | 614.6M | 429.6M | 1.07B | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -48.9M | 0 | -105.6M | 0 | -1.03B | -551.9M | -614.6M | -429.6M | -1.08B | -26K | -41K | 0 | 0 | 0 | -552K | -277K | 1.12M | 50K | -50K | 0 | -1.6M | 0 | 0 | 0 | 0 | 0 | 0 | 100K | -100K | -100K | 0 |
| Cash from Financing | -3.43B | -3.72B | -2.2B | -1.79B | -1.01B | -1.01B | -1.97B | -252.1M | -77.1M | -24.4M | -700.39M | -262.8M | -218.55M | 72.19M | -97.65M | 384.25M | 243.31M | 31.36M | -192.86M | 319.4M | 185.4M | 4.08M | 4.44M | 108.18M | 1.72M | 349.12M | 92.87M | 300K | -1.4M | 39.4M | 66.3M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 1.98B | 0 | 0 | 37.1M | -40.6M | -140.45M | -221.73M | -2.02M | -2.2M | 389.44M | 46.52M | 22.77M | -200.81M | 0 | 0 | 0 | 3.83M | 13.51M | -426K | 190.6M | -1.5M | -1.1M | -1.9M | -3.9M | -3.7M |
| Equity Issued (Net) | -3.05B | -3.33B | -2.17B | -1.79B | -563.3M | 26.9M | -6.53B | -64.1M | 110.1M | -61.5M | -143.2M | 45.82M | -141.54M | 57.39M | -99.75M | 18.51M | 196.79M | 8.6M | 7.95M | 319.4M | 185.01M | 4.08M | 614K | 94.68M | 2.15M | 158.52M | 94.36M | 1.4M | 500K | 43.4M | 70M |
| Dividends Paid | -374.3M | -370.3M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -3.79B | -3.97B | -3.63B | -2.94B | -2.53B | -2.68B | -6.53B | -463.9M | -191.6M | -301.7M | -143.2M | -160.54M | -267.58M | -195.09M | -163.3M | -25.08M | -3.8M | 0 | 0 | 0 | 0 | 0 | -888K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | -10.3M | -33.4M | 0 | -445.7M | -1.03B | 2.58B | -188M | -187.2M | 0 | -516.59M | -168.17M | 144.73M | 16.82M | 4.31M | -23.7M | 0 | 0 | 0 | 0 | 390K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -100K | 0 |
| Net Change in Cash | -122.4M | 634.7M | -248.8M | -381.6M | 221.3M | 690.8M | 577M | 150.1M | 655M | 277.53M | -273.9M | 160.38M | 113.11M | 305.33M | -253.33M | 371.04M | -94.5M | -40.72M | -251.13M | 261.05M | 53.37M | 89.28M | -17.05M | 38.21M | -167.32M | 216.41M | 7.28M | 3.9M | -9.2M | -5.6M | 1.7M |
| Free Cash Flow | 4.16B | 4.08B | 3.66B | 3.67B | 4.42B | 6.53B | 2B | 2B | 1.81B | 1.03B | 974M | 652.85M | 419.43M | 432.27M | -123.95M | -198.9M | -3.35M | -169.55M | -123.94M | 8.93M | 20.26M | -35.26M | -23.08M | -35.79M | -144.89M | -65.54M | -34.41M | -19.5M | -13.2M | -8.2M | -28.9M |
| FCF Margin % | 27.85% | 28.45% | 25.8% | 27.96% | 36.35% | 40.63% | 23.58% | 30.51% | 27% | 17.62% | 20.04% | 15.91% | 14.88% | 20.54% | -8.99% | -44.61% | -0.73% | -44.7% | -51.98% | 7.14% | 31.94% | -53.27% | -13.26% | -62.24% | -658.96% | -298.29% | -58.04% | -56.52% | -34.55% | -24.77% | -119.92% |
| FCF Growth % | 37.58% | 11.35% | -0.08% | -17.11% | -32.23% | 225.9% | 0.15% | 10.4% | 75.16% | 6.21% | 49.19% | 55.65% | -2.97% | 448.74% | 37.68% | -5846.16% | 98.03% | -36.8% | -1488.56% | -55.95% | 157.47% | -52.75% | 35.5% | 75.3% | -121.07% | -90.5% | -76.44% | -47.73% | -60.98% | 71.63% | -34.42% |
| FCF per Share | 38.58 | 37.57 | 31.84 | 32.26 | 38.99 | 58.19 | 17.41 | 17.46 | 15.78 | 8.93 | 8.37 | 5.67 | 3.70 | 3.88 | -1.07 | -2.20 | -0.04 | -2.13 | -1.57 | 0.13 | 0.35 | -0.63 | -0.41 | -0.71 | -3.30 | -1.56 | -0.98 | -0.62 | -0.43 | -0.28 | -1.18 |
| FCF Conversion (FCF/Net Income) | 0.94x | 1.11x | 1.00x | 1.16x | 1.16x | 0.88x | 0.75x | 1.15x | 0.90x | 1.09x | 1.66x | 2.09x | 2.16x | 1.39x | -0.10x | 0.64x | -0.92x | 1.06x | 1.08x | -0.26x | -0.23x | 0.32x | -0.41x | 0.06x | 0.89x | 0.75x | 1.20x | 0.60x | 1.19x | 0.53x | 0.63x |
| Interest Paid | 0 | 0 | 52.6M | 73.1M | 53.7M | 55.8M | 23.2M | 25M | 22.3M | 18.7M | 5.5M | 10.58M | 20.35M | 23.2M | 0 | 0 | 0 | 0 | 9.35M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 743M | 870.3M | 1.5B | 1.22B | 188.1M | 342.3M | 205.6M | 754.8M | 481.4M | 276.09M | 59.85M | 1.06M | 0 | 0 | 0 | 0 | 3.08M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medicare Part B pricing
According to recent financial statements, Regeneron's operating cash flow to net income ratio has fluctuated significantly, reaching a low of 0.25 in 2024Q2, which suggests that reported earnings are frequently decoupled from actual cash generation due to the timing of collaboration settlements and working capital swings.
The wide variance in the OCF/NI ratio indicates that net income is an imperfect proxy for the company's immediate liquidity. Investors should monitor whether these periodic disconnects represent structural delays in collaboration revenue recognition or underlying volatility in the core biologics business.
As reported in quarterly filings, Regeneron's free cash flow margins have demonstrated high sensitivity to operational cycles, ranging from a low of 4.0% in 2024Q2 to a peak of 42.9% in 2024Q1, highlighting the inherent unpredictability of cash flow generation in a platform-heavy biotech model.
This volatility suggests that while the company maintains high-margin products, the timing of R&D investments and collaboration-related cash inflows creates a lumpy cash flow profile. The inability to maintain a consistent FCF margin trajectory warrants further investigation into the predictability of the company's long-term cash conversion.
Based on reported figures, Regeneron's capital expenditure as a percentage of revenue has averaged roughly 7.5% over the last ten quarters, reflecting a sustained commitment to manufacturing capacity that appears necessary to support the complex production requirements of its proprietary monoclonal antibody pipeline.
The consistent level of investment suggests that management prioritizes internal manufacturing control to mitigate supply chain risks. However, investors should monitor whether this capital intensity remains elevated as the company transitions its product portfolio toward newer, potentially more complex bispecific antibody therapies.
Data from recent financial disclosures indicate that Regeneron has prioritized share repurchases over other forms of capital deployment, with buybacks totaling over $1 billion in multiple quarters, even as the company maintains a fortress balance sheet with minimal debt and significant cash reserves.
The reliance on share buybacks as the primary mechanism for returning capital suggests a lack of large-scale, accretive M&A opportunities that meet the company's internal return thresholds. This strategy may indicate management's confidence in the organic pipeline, though it raises questions regarding the potential for future diversification.
Quick answers to the most common questions about buying REGN stock.
Regeneron Pharmaceuticals, Inc. (REGN) generated $4.98B in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Regeneron Pharmaceuticals, Inc. (REGN) generated $4.08B in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Regeneron Pharmaceuticals, Inc. (REGN) spent $1.21B on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Regeneron Pharmaceuticals, Inc. (REGN) returned $370.3M to shareholders via cash dividends and spent $3.97B on share repurchases. This shows the company's commitment to returning capital to its equity investors.