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RGENRepligen Corporation
$173.49$9.8B
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  4. Financial Ratios

Repligen Corporation (RGEN) Financial Ratios

Latest Ratios: P/E Ratio -831.3x · EV/EBITDA 89.4x · ROE 2.4%. (1996–2025 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

RGEN Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Market Cap$9.8B$9.3B$8.1B$10.1B$9.7B$15.2B$10.3B$4.6B$2.4B$1.4B$1.1B
Enterprise Value$9.9B$9.4B$8.0B$10.1B$9.6B$14.9B$9.9B$4.3B$2.3B$1.3B$1.0B
P/E Ratio →-831.29190.53—285.4052.26118.23172.64210.23142.5450.3990.65
P/S Ratio12.1512.5512.6916.0312.1422.6228.2016.8412.3610.0610.05
P/B Ratio4.664.404.085.165.098.676.754.293.902.406.23
P/FCF92.1898.7056.51135.28251.12292.06284.65103.30128.02118.39328.83
P/OCF83.3978.9345.9188.9856.53127.43164.9167.7273.1881.39139.73

P/E links to full P/E history page with 30-year chart

RGEN EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
EV / Revenue—12.7212.5815.9712.0122.2626.9915.8611.899.539.61
EV / EBITDA89.3660.00155.1275.4534.1872.5791.2370.3355.2654.9147.14
EV / EBIT166.42109.78—170.5343.7090.57138.55120.9488.8098.3252.27
EV / FCF—100.0256.01134.75248.53287.48272.4797.28123.19112.18314.28

RGEN Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Gross Margin47.1%47.1%43.3%44.0%56.9%58.3%53.1%51.1%55.7%52.5%54.9%
Operating Margin8.1%8.1%-5.5%7.5%28.0%24.9%22.2%14.8%13.4%9.9%15.3%
Net Profit Margin6.6%6.6%-4.0%5.6%23.2%19.1%16.4%7.9%8.6%20.1%11.2%

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
ROE2.4%2.4%-1.3%1.8%10.2%7.8%4.6%2.6%2.8%7.5%8.0%
ROA1.7%1.7%-0.9%1.3%7.6%6.0%3.6%2.8%12.8%13.9%5.4%
ROIC2.2%2.2%-1.4%1.9%10.1%9.7%6.5%4.6%3.7%3.3%14.0%
ROCE2.2%2.2%-1.3%2.0%10.9%9.4%5.5%5.9%49.6%7.7%8.1%

RGEN Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Debt / Equity0.330.330.350.360.220.210.180.250.170.170.56
Debt / EBITDA4.414.4113.345.321.501.782.544.322.484.054.47
Net Debt / Equity—0.06-0.04-0.02-0.05-0.14-0.29-0.25-0.15-0.13-0.28
Net Debt / EBITDA0.790.79-1.38-0.30-0.36-1.16-4.08-4.35-2.16-3.04-2.18
Debt / FCF—1.32-0.50-0.53-2.59-4.58-12.18-6.02-4.82-6.21-14.55
Interest Coverage3.693.69-0.285.9174.0012.965.883.813.872.135.10

RGEN Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Current Ratio8.378.378.416.742.472.482.8313.282.129.638.74
Quick Ratio7.127.127.285.511.881.992.5312.151.808.087.57
Cash Ratio5.655.655.974.561.541.612.2510.941.496.896.73
Asset Turnover—0.250.220.220.320.280.190.191.391.170.36
Inventory Turnover2.292.292.521.751.451.511.812.412.031.721.91
Days Sales Outstanding—78.4177.1671.6752.9463.9271.1458.9867.2671.6855.98

RGEN Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Earnings Yield—0.5%—0.4%1.9%0.8%0.6%0.5%0.7%2.0%1.1%
FCF Yield1.1%1.0%1.8%0.7%0.4%0.3%0.4%1.0%0.8%0.8%0.3%
Buyback Yield0.0%0.0%0.0%0.1%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Total Shareholder Yield0.0%0.0%0.0%0.1%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Shares Outstanding—$57M$56M$56M$57M$57M$54M$49M$45M$39M$34M

Key Metrics

Growth RegimeMixed
ProfitabilityStrained
Balance SheetAdequate
Cash FlowRobust
Top Statement Risk

Goodwill impairment exposure

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q3)

Premium Pricing Ahead of Returns

At 204x trailing P/E and 72.6x EV/EBITDA, Repligen's pricing embeds a robust recovery that near-zero trailing returns do not yet support; per recent financial data, even the forward P/E of 85.35 assumes the 13% organic growth trajectory holds and margins normalize sharply.

The forward EV/EBITDA of 39.33 versus a trailing 72.62 implies consensus expects roughly a doubling of EBITDA within twelve months, a step-change that would require both the destocking rebound and a recovery toward historical gross margins above 55%. At a P/S of 13.44 and P/B of 4.72 against an equity base where retained earnings actually declined to $431.2M, the market is paying materially ahead of demonstrated book-value creation. Investors should recognize that much of the current multiple is effectively an option on margin recovery rather than a reflection of present earning power.

Gross Recovery Undermined by Cost Base

Repligen's gross margin recovered to 53.0% in 2026Q3 from the 23.2% trough in 2024Q4, yet operating margin swung to -14.1%, implying SG&A and restructuring charges absorbed roughly 67 points; as reported in recent filings, gross profitability is no longer the binding constraint.

The extreme gross margin dispersion between 23.2% and 53.6% over ten quarters suggests capacity utilization and inventory write-downs, rather than pricing, dominate short-term gross profitability, which makes single-quarter gross margin a weak signal of structural economics. More consequentially, operating margin printed at 5.8% and 9.3% in 2026Q2 and Q1 before collapsing to -14.1% in Q3, a pattern that suggests the operating expense base was not scaled to absorb whatever charges or mix shifted in that quarter. Adjusting for non-cash amortization and stock compensation of $8-9.4M quarterly, underlying earning power appears closer to the mid-single-digit operating margin band of 2025 than either extreme implies, but the Q3 swing warrants an explanation before the recovery thesis can be underwritten.

Returns Remain Below Cost of Capital

Per Repligen's ten-quarter ratio history, ROIC has never exceeded 0.7% and printed -1.0% in 2026Q3, far below any plausible cost of capital; ROE of -1.8% on $2.1B equity suggests the $690M debt stack is not the constraint—earnings are.

Because ROIC and ROE have converged in a narrow sub-1% band despite modest leverage, the underperformance appears driven by a depressed numerator rather than capital structure, meaning deleveraging would not improve returns in the current environment. With goodwill at roughly 38% of total assets, reported invested capital is arguably inflated by acquisition premiums; a goodwill-adjusted ROIC would look less negative in loss quarters but would still likely sit well below sector peers such as Sartorius on normalized years. The key judgment is whether the 13% organic growth now being reported can convert into ROIC above the cost of capital without further SG&A expansion—if not, the compounding case weakens considerably.

Inventory Float Absorbs Working Capital

Asset turnover of 0.07 and a cash conversion cycle of 212 days in 2026Q3, with days inventory outstanding at 173 versus DPO of 29, indicate Repligen self-funds a very long inventory tail; per recent quarterly statements, CCC has compressed from the 272-day peak in 2024Q3.

An asset turnover of 0.05-0.07 across the period is structurally low for a nominal manufacturing business, reflecting both the goodwill-heavy balance sheet and a product mix skewed toward high-value, low-velocity consumables; this mechanically depresses any ROA or ROIC framing. The CCC decline from 272 to 212 days appears driven almost entirely by inventory normalization (DIO falling from 222 to 173) rather than supplier leverage, as DPO has remained pinned in the 19-34 day range, meaning the efficiency gain is largely cyclical destocking rather than structural working-capital discipline. If DIO continues to fall toward pre-pandemic levels as bioprocessing utilization recovers, this could become a meaningful cash source, but investors should not extrapolate the 2026Q3 improvement as a permanent run-rate.

Net Cash Masks Thin Coverage

With $727M of cash against $692M of total debt, Repligen's D/E of 0.33 overstates net leverage, yet D/EBITDA of roughly 16–18x and negative 3.69x interest coverage in 2026Q3, based on reported figures, reflect an earnings base too thin for the fixed-charge load.

The apparent paradox of negative interest coverage alongside a net cash position is an artifact of depressed EBITDA in loss quarters rather than a liquidity event; on 2026Q2's profitability profile, coverage of 1.28x was adequate but not generous, suggesting covenant risk is low while refinancing capacity in a stressed scenario would depend on the cash balance being genuinely unrestricted. Debt has been held near $690M for eight quarters with no meaningful amortization, implying management is treating the stack as term financing rather than a facility to be worked down. The more relevant leverage consideration is not the debt itself but the roughly $125M of net acquisition spend over ten quarters, which converts balance-sheet flexibility into goodwill exposure that cannot be reversed in a downturn.

P/E Misleads on Capital-Heavy Model

The trailing P/E of 204.42 is the most misleading ratio here, inflated by $19.1M of quarterly D&A and acquisition amortization against a thin GAAP profit base; company filings suggest normalized pre-amortization earnings, not the headline multiple, should anchor valuation work.

Because Repligen has compounded growth largely through acquisitions, GAAP net income is systematically depressed by intangible amortization, making the trailing P/E—and to a lesser extent EV/EBITDA, which includes that same amortization—unreliable across the cycle; a forward EV/EBITDA ex-amortization or an FCF yield against normalized free cash flow is the more durable lens. The misapplied counterpart on the operating side is ROIC: with goodwill representing approximately 38% of assets, reported ROIC of -1.0% overstates capital destruction in the sense that it charges the full acquisition premium against returns, though even adjusted it appears unlikely to clear a reasonable hurdle rate in the current margin environment. Analysts applying sector-standard P/E or ROIC frameworks to Repligen should therefore substitute adjusted operating earnings and cash-return measures, or they risk reaching either an unfounded valuation anchor or an unfairly harsh assessment of capital efficiency.

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RGEN — Frequently Asked Questions

Quick answers to the most common questions about buying RGEN stock.

What is Repligen Corporation's P/E ratio?

Repligen Corporation's current P/E ratio is -831.3x. The historical average is 88.0x.

What is Repligen Corporation's EV/EBITDA?

Repligen Corporation's current EV/EBITDA is 89.4x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 49.1x.

What is Repligen Corporation's ROE?

Repligen Corporation's return on equity (ROE) is 2.4%. The historical average is -4.8%.

Is RGEN stock overvalued?

Based on historical data, Repligen Corporation is trading at a P/E of -831.3x. Compare with industry peers and growth rates for a complete picture.

What are Repligen Corporation's profit margins?

Repligen Corporation has 47.1% gross margin and 8.1% operating margin.

How much debt does Repligen Corporation have?

Repligen Corporation's Debt/EBITDA ratio is 4.4x, indicating high leverage. A ratio above 4x may signal elevated financial risk.