Last 48 quarters of trend data · Healthcare · Life Science Tools
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q3 '26 | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -831.29 | — | 379.00 | 196.37 | 178.11 | 128.53 | 119.60 | 318.10 | — | 116.27 | 535.97 | 1149.50 | — | 124.23 | 101.04 | 82.53 | 49.80 | 65.88 | 46.14 | 58.78 | 132.42 |
| — | — | +216.9% | -38.3% | — | +10.5% | -77.7% | -72.3% | — | -6.4% | +430.4% | +1292.8% | — | +88.6% | +119.0% | +40.4% | -62.4% | -47.1% | -40.8% | -37.1% | -0.5% | |
| P/S Ratio | 12.15 | 12.99 | 9.47 | 8.59 | 11.70 | 10.00 | 9.64 | 10.63 | 12.04 | 13.68 | 11.20 | 16.97 | 16.11 | 16.03 | 12.63 | 14.52 | 12.94 | 13.35 | 11.09 | 13.40 | 20.49 |
| — | +29.8% | -1.7% | -19.2% | -2.8% | -26.9% | -13.9% | -37.3% | -25.3% | -14.7% | -11.4% | +16.9% | +24.5% | +20.1% | +13.9% | +8.4% | -36.8% | -42.6% | -36.2% | -30.8% | -15.6% | |
| P/B Ratio | 4.66 | 5.20 | 3.66 | 3.17 | 4.40 | 3.63 | 3.41 | 3.62 | 4.09 | 4.20 | 3.58 | 5.28 | 5.11 | 4.55 | 4.08 | 4.95 | 5.06 | 5.84 | 5.10 | 6.26 | 8.73 |
| — | +43.3% | +7.4% | -12.5% | +7.5% | -13.7% | -4.8% | -31.3% | -19.9% | -7.7% | -12.2% | +6.6% | +0.9% | -22.1% | -20.0% | -21.0% | -42.1% | -39.5% | -27.8% | -11.8% | +26.7% | |
| P/FCF | 92.18 | 71.24 | 69.85 | 71.49 | 135.83 | 44.22 | 83.66 | 170.13 | 62.67 | 50.22 | 51.12 | 71.54 | 139.79 | 74.99 | 80.18 | 1395.23 | 59.69 | — | 118.09 | — | 235.04 |
| — | +61.1% | -16.5% | -58.0% | +116.7% | -12.0% | +63.6% | +137.8% | -55.2% | -33.0% | -36.2% | -94.9% | +134.2% | — | -32.1% | — | -74.6% | — | -14.8% | — | -71.7% | |
| EV / EBITDA | 89.36 | — | 54.73 | 39.87 | 54.38 | 45.44 | 45.30 | 60.33 | — | 153.46 | 61.31 | 103.32 | 153.73 | 90.19 | 55.55 | 81.33 | 37.84 | 40.43 | 30.00 | 37.84 | 77.65 |
| — | — | +20.8% | -33.9% | — | -70.4% | -26.1% | -41.6% | — | +70.2% | +10.4% | +27.0% | +306.3% | +123.1% | +85.2% | +115.0% | -51.3% | -45.1% | -37.0% | -36.1% | -8.3% | |
| EV / EBIT | 166.42 | — | 88.22 | 218.22 | 93.76 | 83.18 | 74.31 | 136.11 | — | 526.20 | 120.15 | 296.72 | — | 187.53 | 77.64 | 125.35 | 44.92 | 55.27 | 37.61 | 45.89 | 98.76 |
| — | — | +18.7% | +60.3% | — | -84.2% | -38.1% | -54.1% | — | +180.6% | +54.7% | +136.7% | — | +239.3% | +106.4% | +173.1% | -54.5% | -39.6% | -34.5% | -37.4% | -30.1% |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q3 '26 | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 47.1% | 53.0% | 53.1% | 50.7% | 47.2% | 53.2% | 50.0% | 53.6% | 23.2% | 50.0% | 46.2% | 50.1% | 43.4% | 25.9% | 50.2% | 50.5% | 51.4% | 56.9% | 58.5% | 60.1% | 56.0% |
| — | -0.4% | +6.2% | -5.5% | +103.7% | +6.4% | +8.2% | +7.0% | -46.6% | +93.2% | -8.0% | -0.8% | -15.6% | -54.5% | -14.2% | -16.0% | -8.2% | -1.3% | -5.7% | +3.3% | +8.3% | |
| Operating Margin | 8.1% | -14.1% | 5.8% | 9.3% | 9.4% | 8.9% | 7.6% | 3.9% | -21.8% | -5.1% | 4.7% | 2.4% | -0.6% | 3.3% | 12.1% | 8.4% | 26.1% | 26.2% | 30.4% | 29.1% | 20.1% |
| — | -258.4% | -23.3% | +138.2% | +143.0% | +276.2% | +62.7% | +58.8% | -3725.4% | -252.2% | -61.3% | -70.8% | -102.2% | -87.3% | -60.2% | -71.2% | +30.3% | +3.5% | +2.8% | +14.1% | -2.4% | |
| Net Margin | 6.6% | -18.4% | 2.5% | 4.3% | 6.7% | 7.9% | 8.2% | 3.4% | -20.2% | -0.4% | 3.6% | 2.2% | -16.4% | 12.0% | 12.4% | 9.3% | 26.1% | 20.1% | 24.0% | 22.8% | 15.6% |
| — | -332.5% | -69.9% | +24.5% | +133.2% | +1970.1% | +126.6% | +60.2% | -23.5% | -103.5% | -71.1% | -76.8% | -162.7% | -40.5% | -48.2% | -59.2% | +67.2% | +7.1% | +8.0% | +10.4% | -13.9% |
| Metric | TTM | Q3 '26 | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 2.4% | -1.8% | 0.2% | 0.4% | 0.6% | 0.7% | 0.7% | 0.3% | -1.7% | -0.0% | 0.3% | 0.2% | -1.3% | 0.9% | 1.0% | 0.8% | 2.6% | 2.2% | 2.8% | 2.7% | 1.7% |
| — | -354.1% | -67.7% | +34.3% | +137.4% | +2300.3% | +154.4% | +75.9% | -31.7% | -103.8% | -71.5% | -79.0% | -149.6% | -61.5% | -63.8% | -70.2% | +54.9% | +9.9% | +21.7% | +39.9% | +13.2% | |
| ROA | 1.7% | -1.3% | 0.2% | 0.3% | 0.5% | 0.5% | 0.5% | 0.2% | -1.2% | -0.0% | 0.2% | 0.1% | -1.0% | 0.7% | 0.8% | 0.6% | 2.0% | 1.6% | 2.1% | 2.0% | 1.3% |
| — | -355.5% | -67.0% | +38.1% | +137.8% | +2325.7% | +158.2% | +76.9% | -25.5% | -103.4% | -74.3% | -80.8% | -148.9% | -59.4% | -62.3% | -69.5% | +54.2% | +4.6% | +12.4% | +28.8% | +8.6% | |
| ROIC | 2.2% | -1.0% | 0.4% | 0.6% | 0.7% | 0.6% | 0.5% | 0.3% | -1.4% | -0.3% | 0.3% | 0.1% | -0.0% | 0.2% | 0.8% | 0.6% | 2.1% | 2.4% | 3.0% | 2.9% | 1.9% |
| — | -267.7% | -21.9% | +138.6% | +145.5% | +302.3% | +79.1% | +74.5% | -3906.4% | -255.7% | -63.5% | -74.3% | -101.7% | -91.7% | -73.1% | -80.5% | +9.2% | -9.0% | -5.9% | +18.1% | +10.7% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q3 '26 | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.33 | 0.33 | 0.33 | 0.33 | 0.33 | 0.33 | 0.33 | 0.34 | 0.35 | 0.33 | 0.37 | 0.37 | 0.36 | 0.21 | 0.21 | 0.22 | 0.22 | 0.23 | 0.23 | 0.22 | 0.21 |
| — | +0.1% | -1.7% | -5.2% | -5.8% | -0.8% | -11.0% | -8.0% | -4.0% | +57.9% | +74.3% | +72.7% | +63.7% | -7.4% | -7.0% | -2.7% | +5.8% | +24.7% | +20.9% | +23.9% | +16.1% | |
| Debt / EBITDA | 4.41 | — | 19.35 | 16.17 | 15.99 | 16.71 | 17.75 | 22.97 | — | 49.36 | 25.85 | 29.45 | 43.79 | 17.13 | 11.95 | 14.39 | 6.69 | 6.41 | 5.54 | 5.48 | 7.56 |
| — | — | +9.1% | -29.6% | — | -66.2% | -31.4% | -22.0% | — | +188.2% | +116.3% | +104.6% | +554.5% | +167.4% | +115.9% | +162.7% | -11.4% | +12.7% | +3.5% | -12.1% | -18.2% | |
| Current Ratio | 8.37 | 9.88 | 9.05 | 9.20 | 8.37 | 8.36 | 8.59 | 6.79 | 8.41 | 10.44 | 6.65 | 6.35 | 6.74 | 2.69 | 2.67 | 2.51 | 2.47 | 2.32 | 2.30 | 2.23 | 2.48 |
| — | +18.2% | +5.3% | +35.5% | -0.4% | -19.9% | +29.2% | +6.9% | +24.8% | +287.8% | +148.7% | +152.8% | +172.9% | +16.0% | +16.0% | +12.9% | -0.5% | -11.0% | -22.2% | -24.7% | -12.2% | |
| Quick Ratio | 7.12 | 8.43 | 7.64 | 7.78 | 7.12 | 7.14 | 7.32 | 5.79 | 7.28 | 8.76 | 5.56 | 5.24 | 5.51 | 2.11 | 2.03 | 1.91 | 1.88 | 1.73 | 1.74 | 1.72 | 1.99 |
| — | +18.1% | +4.4% | +34.5% | -2.2% | -18.5% | +31.8% | +10.3% | +32.1% | +314.9% | +173.9% | +174.5% | +193.2% | +22.0% | +16.6% | +10.9% | -5.6% | -19.9% | -31.8% | -33.9% | -21.3% | |
| Interest Coverage | 3.69 | -3.69 | 1.28 | 1.30 | 4.23 | 0.82 | 4.09 | 2.33 | -6.07 | 0.72 | 2.67 | 1.58 | -0.96 | 13.60 | 29.17 | 21.92 | 73.46 | 60.96 | 82.91 | 79.60 | 11.74 |
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Includes 30+ ratios · 48 years · Updated daily
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Quick answers to the most common questions about buying RGEN stock.
Repligen Corporation's current P/E is -831.3x. The average P/E over the last 3 quarters is 251.2x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Repligen Corporation's current operating margin is 8.1%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Repligen Corporation's business trajectory between earnings reports.