Last 48 quarters of trend data · Healthcare · Medical - Instruments & Supplies
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
Repligen Corporation's quarterly P/E stands at 196.4x, down 38.3% year-over-year — suggesting improving earnings relative to price. EV/EBITDA has compressed 24.2% YoY to 45.8x, reflecting multiple compression or accelerating EBITDA.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | 153.51 | 196.37 | 178.11 | 128.53 | 119.60 | 318.10 | — | 116.27 | 535.97 | 1149.50 | — | 124.23 | 101.04 |
| — | -38.3% | — | +10.5% | -77.7% | -72.3% | — | -6.4% | +430.4% | +1292.8% | — | +88.6% | +119.0% | |
| P/S Ratio | 10.09 | 8.59 | 11.70 | 10.00 | 9.64 | 10.63 | 12.04 | 13.68 | 11.20 | 16.97 | 16.11 | 16.03 | 12.63 |
| — | -19.2% | -2.8% | -26.9% | -13.9% | -37.3% | -25.3% | -14.7% | -11.4% | +16.9% | +24.5% | +20.1% | +13.9% | |
| P/B Ratio | 3.55 | 3.17 | 4.40 | 3.63 | 3.41 | 3.62 | 4.09 | 4.20 | 3.58 | 5.28 | 5.11 | 4.55 | 4.08 |
| — | -12.5% | +7.5% | -13.7% | -4.8% | -31.3% | -19.9% | -7.7% | -12.2% | +6.6% | +0.9% | -22.1% | -20.0% | |
| P/FCF | 79.30 | 70.77 | 135.83 | 44.22 | 83.66 | 170.13 | 62.67 | 50.22 | 51.12 | 71.54 | 139.79 | 74.99 | 80.18 |
| — | -58.4% | +116.7% | -12.0% | +63.6% | +137.8% | -55.2% | -33.0% | -36.2% | -94.9% | +134.2% | — | -32.1% | |
| EV / EBITDA | 54.72 | 45.76 | 60.93 | 45.44 | 45.30 | 60.33 | — | 217.97 | 61.31 | 103.32 | 153.73 | 90.19 | 55.55 |
| — | -24.2% | — | -79.2% | -26.1% | -41.6% | — | +141.7% | +10.4% | +27.0% | +306.3% | +123.1% | +85.2% | |
| EV / EBIT | 127.06 | 98.05 | 93.76 | 83.18 | 74.31 | 136.11 | — | 526.20 | 120.15 | 296.72 | — | 187.53 | 77.64 |
| — | -28.0% | — | -84.2% | -38.1% | -54.1% | — | +180.6% | +54.7% | +136.7% | — | +239.3% | +106.4% |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Repligen Corporation's operating margin was 8.9% in Q1 2026, down 0.5 pp QoQ and up 5.0 pp YoY. Gross margin expanded 3.9% YoY, indicating pricing power or improving input costs.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 47.1% | 55.7% | 47.2% | 53.2% | 50.0% | 53.6% | 23.2% | 50.0% | 46.2% | 50.1% | 43.4% | 25.9% | 50.2% |
| — | +3.9% | +103.7% | +6.4% | +8.2% | +7.0% | -46.6% | +93.2% | -8.0% | -0.8% | -15.6% | -54.5% | -14.2% | |
| Operating Margin | 8.1% | 8.9% | 9.4% | 8.9% | 7.6% | 3.9% | -21.8% | -5.1% | 4.7% | 2.4% | -0.6% | 3.3% | 12.1% |
| — | +128.9% | +143.0% | +276.2% | +62.7% | +58.8% | -3725.4% | -252.2% | -61.3% | -70.8% | -102.2% | -87.3% | -60.2% | |
| Net Margin | 6.6% | 4.3% | 6.7% | 7.9% | 8.2% | 3.4% | -20.2% | -0.4% | 3.6% | 2.2% | -16.4% | 12.0% | 12.4% |
| — | +24.5% | +133.2% | +1970.1% | +126.6% | +60.2% | -23.5% | -103.5% | -71.1% | -76.8% | -162.7% | -40.5% | -48.2% |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 2.4% | 0.4% | 0.6% | 0.7% | 0.7% | 0.3% | -1.7% | -0.0% | 0.3% | 0.2% | -1.3% | 0.9% | 1.0% |
| — | +34.3% | +137.4% | +2300.3% | +154.4% | +75.9% | -31.7% | -103.8% | -71.5% | -79.0% | -149.6% | -61.5% | -63.8% | |
| ROA | 1.7% | 0.3% | 0.5% | 0.5% | 0.5% | 0.2% | -1.2% | -0.0% | 0.2% | 0.1% | -1.0% | 0.7% | 0.8% |
| — | +38.1% | +137.8% | +2325.7% | +158.2% | +76.9% | -25.5% | -103.4% | -74.3% | -80.8% | -148.9% | -59.4% | -62.3% | |
| ROIC | 2.2% | 0.6% | 0.7% | 0.6% | 0.5% | 0.3% | -1.4% | -0.3% | 0.3% | 0.1% | -0.0% | 0.2% | 0.8% |
| — | +129.3% | +145.5% | +302.3% | +79.1% | +74.5% | -3906.4% | -255.7% | -63.5% | -74.3% | -101.7% | -91.7% | -73.1% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
Repligen Corporation's Debt/EBITDA ratio is 18.6x, up from 17.9x last quarter — elevated, raising questions about debt serviceability. The current ratio has improved 35.5% YoY to 9.20x, strengthening the short-term liquidity position. Debt/Equity has declined for 6 consecutive quarters, reflecting a deleveraging trend.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.33 | 0.33 | 0.33 | 0.33 | 0.33 | 0.34 | 0.35 | 0.33 | 0.37 | 0.37 | 0.36 | 0.21 | 0.21 |
| — | -5.2% | -5.8% | -0.8% | -11.0% | -8.0% | -4.0% | +57.9% | +74.3% | +72.7% | +63.7% | -7.4% | -7.0% | |
| Debt / EBITDA | 4.99 | 18.56 | 17.92 | 16.71 | 17.75 | 22.97 | — | 70.11 | 25.85 | 29.45 | 43.79 | 17.13 | 11.95 |
| — | -19.2% | — | -76.2% | -31.4% | -22.0% | — | +309.3% | +116.3% | +104.6% | +554.5% | +167.4% | +115.9% | |
| Current Ratio | 8.37 | 9.20 | 8.37 | 8.36 | 8.59 | 6.79 | 8.41 | 10.44 | 6.65 | 6.35 | 6.74 | 2.69 | 2.67 |
| — | +35.5% | -0.4% | -19.9% | +29.2% | +6.9% | +24.8% | +287.8% | +148.7% | +152.8% | +172.9% | +16.0% | +16.0% | |
| Quick Ratio | 7.12 | 7.78 | 7.12 | 7.14 | 7.32 | 5.79 | 7.28 | 8.76 | 5.56 | 5.24 | 5.51 | 2.11 | 2.03 |
| — | +34.5% | -2.2% | -18.5% | +31.8% | +10.3% | +32.1% | +314.9% | +173.9% | +174.5% | +193.2% | +22.0% | +16.6% | |
| Interest Coverage | 3.69 | 3.10 | 4.23 | 0.82 | 4.09 | 2.33 | -6.07 | 0.72 | 2.67 | 1.58 | -0.96 | 13.60 | 29.17 |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 48 years · Updated daily
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Quick answers to the most common questions about buying RGEN stock.
Repligen Corporation's current P/E is 153.5x. The average P/E over the last 4 quarters is 155.7x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Repligen Corporation's current operating margin is 8.1%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Repligen Corporation's business trajectory between earnings reports.