Even in its strongest reported quarter, operating cash flow was negative $62.2M against $22.7M of net income (an OCF-to-earnings ratio of -2.74) with a negative $103.3M working capital swing, underscoring that headline profitability has not translated into cash generation and that cumulative burn near $442M warrants further investigation.
REGENXBIO Inc. (RGNX) cash flow statement — 13-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|
| Cash from Operations | -246.67M | -123.96M | -173.13M | -218.41M | -207.49M | 218.88M | -54.06M | -107.7M | 104.65M | -57.99M | -48.56M | -22.52M | -2.4M | -3.01M |
| Operating CF Margin % | - | -72.73% | -207.76% | -242.02% | -184.07% | 46.53% | -34.98% | -305.69% | 47.89% | -557.99% | -1058.14% | -296.72% | -39.2% | -49.48% |
| Operating CF Growth % | -456.04% | 28.4% | 20.73% | -5.26% | -194.8% | 504.87% | 49.81% | -202.92% | 280.45% | -19.43% | -115.67% | -838.52% | 20.35% | - |
| Net Income | -196.43M | -193.88M | -227.1M | -263.49M | -280.32M | 127.84M | -111.25M | -94.73M | 99.94M | -73.17M | -62.97M | -22.81M | -4M | -5.39M |
| Depreciation & Amortization | 15.37M | 15.62M | 16.21M | 17.32M | 12.91M | 9.56M | 8.41M | 7.15M | 3.98M | 2.69M | 544K | 80K | 0 | 0 |
| Stock-Based Compensation | 35.04M | 34.56M | 38.46M | 40.27M | 40.79M | 38.81M | 31.95M | 26.85M | 16.64M | 10.61M | 7.03M | 2.92M | 319K | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | -1.92M | 3.84M | -38.97M | 794K | 1.34M | 2M | 322K | 0 | 0 |
| Other Non-Cash Items | 16.3M | 7.96M | -6.23M | -1.61M | 5.16M | 4.36M | -1.23M | -2.68M | -8.93M | -347K | -399K | 13K | 175K | -289K |
| Working Capital Changes | -116.95M | 11.78M | 5.53M | -10.89M | 13.98M | 40.22M | 14.22M | -5.33M | -7.77M | 897K | 5.23M | -3.04M | 1.11M | 2.66M |
| Change in Receivables | -85.34M | -7.66M | 9.71M | 3.94M | 4.82M | 14.12M | -9.9M | -8.62M | -16.8M | 561K | 1.07M | -1.34M | -799K | -36K |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 29.3M | 17.85M | 2.37M | 5.35M | -2.2M | 2.82M | -2.51M | 1.72M | 4.89M |
| Change in Payables | -6.11M | -2.28M | -292K | -2.79M | 18.79M | -2.3M | 3.87M | 1.53M | -218K | 2.62M | 186K | 590K | 33K | 257K |
| Cash from Investing | 216.34M | -15.87M | 103.45M | 190.94M | -11.93M | -406.64M | 122.76M | 93.56M | -279.36M | -4.79M | 19.16M | -163.8M | 0 | 0 |
| Capital Expenditures | -2.99M | -2.41M | -2.44M | -9.96M | -30.72M | -84.17M | -26.87M | -11.72M | -13.28M | -7.16M | -8.15M | -522K | 0 | 0 |
| CapEx % of Revenue | 1.72% | 1.42% | 2.92% | 11.04% | 27.26% | 17.9% | 17.38% | 33.26% | 6.08% | 68.89% | 177.58% | 6.88% | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | -4.99M | -149.63M | -295.98M | -179.71M | -479K | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 62K | 5.78M | 0 | 0 | 4.99M | 149.63M | 295.98M | 179.71M | 479K | -225K | -163.28M | 0 | 0 |
| Cash from Financing | -12.73M | 116.77M | 92.68M | -34.97M | -28.84M | 195.25M | 200.21M | 8.38M | 204.44M | 84.6M | 119K | 239.31M | 2.4M | 1.97M |
| Debt Issued (Net) | -144.53M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.4M | 0 |
| Equity Issued (Net) | 20.85M | 1.01M | 132.26M | 6.7M | 1.74M | 218.21M | 1.8M | 1.31M | 190.56M | 82.55M | 0 | 239.2M | 0 | 1.97M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 1.19M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 110.94M | 115.76M | -39.58M | -41.67M | -30.58M | -22.96M | 198.41M | 7.06M | 13.88M | 2.05M | 119K | 107K | 1K | 0 |
| Net Change in Cash | -43.07M | -23.06M | 23M | -62.43M | -248.26M | 7.48M | 268.91M | -5.77M | 29.73M | 21.82M | -29.28M | 52.99M | 2K | -1.05M |
| Free Cash Flow | -249.67M | -126.38M | -175.56M | -228.37M | -238.21M | 134.7M | -80.93M | -119.42M | 91.37M | -65.15M | -56.71M | -23.04M | -2.4M | -3.01M |
| FCF Margin % | -143.09% | -74.15% | -210.69% | -253.06% | -211.32% | 28.64% | -52.36% | -338.96% | 41.82% | -626.88% | -1235.72% | -303.6% | -39.2% | -49.48% |
| FCF Growth % | -175.25% | 28.02% | 23.12% | 4.13% | -276.85% | 266.44% | 32.23% | -230.7% | 240.24% | -14.89% | -146.16% | -860.28% | 20.35% | - |
| FCF per Share | -4.71 | -2.45 | -3.55 | -5.22 | -5.52 | 3.07 | -2.17 | -3.25 | 2.49 | -2.18 | -2.15 | -2.51 | -0.18 | -1.14 |
| FCF Conversion (FCF/Net Income) | 1.27x | 0.64x | 0.76x | 0.83x | 0.74x | 1.71x | 0.49x | 1.14x | 1.05x | 0.79x | 0.77x | 0.99x | 0.60x | 0.56x |
| Interest Paid | 0 | 0 | 0 | 0 | 23.12M | 21.64M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 11.81M | 6M | 0 | 904K | 3.44M | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying RGNX stock.
REGENXBIO Inc. (RGNX) generated $-124.0M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
REGENXBIO Inc. (RGNX) reported negative free cash flow of $126.4M in 2025, indicating capital requirements exceeded cash from operations.
REGENXBIO Inc. (RGNX) spent $2.4M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Persistent negative operating cash flow
Metrics are mathematically derived from official filings.
Profitable Quarter Still Cash Negative
Despite reported net income of $22.7M in 2026Q2, REGENXBIO's operating cash flow was negative $62.2M, an OCF-to-net-income ratio of -2.74, according to the company's quarterly cash flow statements — the widest earnings-to-cash gap in the ten-quarter series observed.
Nine of the last ten quarters show negative operating cash flow, meaning reported profitability remains disconnected from actual cash generation; the 2026Q2 gap appears driven largely by a $103.3M working capital outflow rather than operating deterioration per se, which warrants investigation into whether the earnings are recurring or settlement-related. Even excluding that swing, prior quarters show net losses narrowing toward positive net income without any corresponding move in operating cash flow, suggesting the earnings inflection flagged in the income statement analysis has not translated into self-funded operations.
Free Cash Flow Burn Deepens
REGENXBIO's free cash flow deteriorated to negative $63.0M in 2026Q2, and cumulative free cash flow across the ten reported quarters totals roughly negative $442M, based on the company's reported statements — a burn profile with no demonstrated trajectory toward breakeven.
Quarterly free cash flow has ranged from positive $32.6M in 2025Q1 to negative $77.4M in 2026Q1, with no discernible improving trend; the 2026Q2 shortfall of $63.0M is wider than the $49.7M recorded in 2025Q2, implying that milestone revenue timing has not structurally reduced the funding requirement. Because FCF margins have swung between positive 36.6% and negative 189.9% within the period, investors should treat any extrapolation of the most recent quarter's revenue as unreliable for underwriting the cash trajectory.
Milestone Timing Distorts Working Capital
In a quarter reporting positive net income, REGENXBIO's working capital change was negative $103.3M, representing more than four times the quarter's reported earnings, per its 2026Q2 statements — an outsized swing that appears inconsistent with the revenue recognized in the same period.
Working capital has been volatile throughout the ten-quarter window, ranging from positive $16.4M to negative $103.3M, indicating that cash conversion is being driven by milestone recognition and settlement timing rather than a stable operating cycle — no predictable pattern of collections versus payables emerges to guide near-term cash forecasting. The size of the 2026Q2 outflow relative to the quarter's $108M revenue suggests material cash obligations may be attached to revenue events not fully visible in the income statement, and investors should monitor subsequent quarters to determine whether this represents a recurring timing pattern or a one-time settlement.
Zero Returns on Capital Deployed
Across the ten reported quarters, REGENXBIO paid no dividends, repurchased only $0.3M of stock in 2025Q1, and reported no acquisitions — all available capital, per the company's cash flow statements, has been retained against an operating cash burn exceeding $440M.
The absence of shareholder returns despite two quarters of positive net income suggests the cash position is being conserved to fund ongoing research and development rather than distributed, which is consistent with a pre-commercial-stage capital allocation profile. With capex averaging well under $1M per quarter against cumulative burn of this magnitude, the company appears reliant on external financing rather than internally generated cash; the durability of that access, and any dilutive terms attached to it, warrants further scrutiny beyond what the cash flow statement alone reveals.
Non-Cash Adjustments Mask the Burn
Stock-based compensation of $9.1M in 2026Q2 was added back to operating cash flow, representing roughly 18% of the cumulative $89.7M in SBC across ten quarters, while cumulative net losses approached $498M, per REGENXBIO's reported figures — meaning reported cash burn still understates true economic outflow.
Because SBC is a recurring non-cash charge that dilutes shareholders without appearing in operating cash flow, the true cost of the company's operations is closer to the sum of operating cash outflow and SBC than the headline operating cash figure suggests; with SBC exceeding the entire revenue base in trough quarters such as 2026Q1, the dilution burden compounds even as the company remains cash-flow negative. Additionally, the $3.8M quarterly depreciation figure sits far above the $0.5M–$1.2M capex range, implying the company is not replacing its existing asset base — a pattern that may be defensible for a research-stage business but makes reported operating cash flow a poor proxy for sustainable spending requirements.