Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in SCYX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Squadron Capital Management LLC | 7.6M | $7.0M | β | 120.990% | 2.89% |
| 2 | GREAT POINT PARTNERS LLC | 7.6M | $6.9M | β | 120.125% | 1.70% |
| 3 | Avidity Partners Management LP | 2.1M | $1.9M | 0.0% | 33.102% | 0.44% |
| 4 | HEIGHTS CAPITAL MANAGEMENT, INC | 2.1M | $1.9M | β | 33.186% | 0.54% |
| 5 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 2.0M | $1.8M | β | 31.525% | 0.29% |
| 6 | Empery Asset Management, LP | 1.8M | $1.7M | β | 29.383% | 2.04% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 1.6M | $1.4M | β | 24.876% | 0.00% |
| 8 | DAFNA Capital Management LLC | 1.1M | $997K | β | 17.284% | 0.23% |
| 9 | MILLENNIUM MANAGEMENT LLC | 622K | $570K | β | 9.893% | 0.00% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 486K | $446K | +8.3% | 7.734% | 0.00% |
| 11 | BlackRock, Inc. | 332K | $305K | -0.7% | 5.282% | 0.00% |
| 12 | VANGUARD FIDUCIARY TRUST CO | 226K | $207K | β | 3.590% | 0.00% |
| 13 | RENAISSANCE TECHNOLOGIES LLC | 225K | $206K | +27.6% | 3.572% | 0.00% |
| 14 | Yakira Capital Management, Inc. | 189K | $173K | -0.6% | 2.999% | 0.05% |
| 15 | CITADEL ADVISORS LLC | 131K | $120K | +25.9% | 2.080% | 0.00% |
| 16 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 124K | $114K | -24.1% | 1.979% | 0.00% |
| 17 | Empowered Funds, LLC | 124K | $113K | 0.0% | 1.967% | 0.00% |
| 18 | STATE STREET CORP | 121K | $111K | 0.0% | 1.920% | 0.00% |
| 19 | NORTHERN TRUST CORP | 96K | $88K | +26.7% | 1.520% | 0.00% |
| 20 | WEALTH EFFECTS LLC | 88K | $80K | -4.4% | 1.391% | 0.03% |
| 21 | Nierenberg Investment Management Company, Inc. | 76K | $69K | 0.0% | 1.201% | 0.03% |
| 22 | XTX Topco Ltd | 52K | $48K | β | 0.831% | 0.00% |
| 23 | LPL Financial LLC | 38K | $35K | -19.8% | 0.612% | 0.00% |
| 24 | RAYMOND JAMES FINANCIAL INC | 35K | $32K | +5.3% | 0.559% | 0.00% |
| 25 | Bank of New York Mellon Corp | 29K | $26K | -17.7% | 0.459% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in SCYX β a direct measure of their conviction.
Filings activity in SCYX during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 45 | +15% | 99.81% | +80.65 pp | $27M | +421% |
| Q4 2025 | 39 | 9.3% | 19.16% | 13.78 pp | $5M | 42% |
| Q3 2025 | 43 | +4.9% | 32.94% | +5.98 pp | $9M | +22% |
| Q2 2025 | 41 | 2.4% | 26.96% | 13.37 pp | $7M | 33% |
| Q1 2025 | 42 | 14% | 40.33% | 12.01 pp | $11M | 23% |
| Q4 2024 | 49 | +8.9% | 52.34% | 18.28 pp | $14M | 26% |
| Q3 2024 | 45 | 18% | 70.62% | 31.69 pp | $19M | 31% |
| Q2 2024 | 55 | β | 102.31% | β | $27M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying SCYX stock.
Based on Q1 2026 13F filings, institutional ownership of SCYNEXIS, Inc. stands at 99.8%, held across 45 reporting institutions.
Squadron Capital Management LLC is the largest reported institutional holder of SCYX, with approximately 7,608,695 shares worth $0.01B as of Q1 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of SCYX, including MILLENNIUM MANAGEMENT LLC, RENAISSANCE TECHNOLOGIES LLC, CITADEL ADVISORS LLC.
Our composite Smart Money Score for SCYX is 75 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
14 institutions opened new positions in SCYX during Q1 2026, while 8 fully exited. 24 added to existing positions and 5 trimmed.
SCYX institutional ownership rose by 80.65 percentage points quarter-over-quarter, with a net change of +6 holders.
The top 10 institutions account for 93.1% of all reported 13F value in SCYX, and the top 25 account for 99.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
SCYNEXIS, Inc. (SCYX) Institutional Ownership