Latest Ratios: P/E Ratio -3.2x · EV/EBITDA N/A · ROE -45.7%. (2017–2025 historical series)
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $1.6B | $835M | $1.0B | $1.3B | $3.4B | $5.6B | $3.2B | $1.4B | — | — |
| Enterprise Value | $1.6B | $788M | $875M | $1.2B | $2.7B | $5.4B | $2.8B | $1.2B | — | — |
| P/E Ratio → | -3.17 | — | — | — | 6.61 | 10.57 | — | — | — | — |
| P/S Ratio | 23.59 | 12.18 | 13.48 | 15.66 | 2.11 | 5.10 | 47.45 | 1904.67 | — | — |
| P/B Ratio | 1.82 | 1.09 | 0.87 | 0.85 | 1.64 | 3.90 | 4.45 | 3.19 | — | — |
| P/FCF | — | — | — | — | 2.14 | — | — | — | — | — |
| P/OCF | — | — | — | — | 2.05 | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 11.50 | 11.79 | 14.30 | 1.67 | 4.91 | 42.01 | 1751.23 | — | — |
| EV / EBITDA | — | — | — | — | 3.20 | 12.60 | — | — | — | — |
| EV / EBIT | — | — | — | — | 3.23 | 12.78 | — | — | — | — |
| EV / FCF | — | — | — | — | 1.69 | — | — | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 82.9% | 82.9% | -545.0% | -564.7% | 61.6% | 53.1% | 100.0% | 100.0% | -11447.1% | -41854.4% |
| Operating Margin | -682.7% | -682.7% | -791.3% | -794.0% | 51.6% | 38.4% | -441.6% | -25032.2% | -13674.2% | -54696.0% |
| Net Profit Margin | -638.9% | -638.9% | -703.4% | -713.7% | 31.9% | 48.3% | -444.1% | -24568.6% | -13350.7% | -46880.5% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -45.7% | -45.7% | -38.1% | -33.5% | 29.4% | 49.2% | -52.4% | -142.7% | — | — |
| ROA | -36.5% | -36.5% | -31.5% | -26.1% | 21.7% | 36.8% | -41.7% | -49.6% | -52.3% | -27.8% |
| ROIC | -40.3% | -40.3% | -35.3% | -36.3% | 48.5% | 40.1% | -67.0% | -271.8% | — | — |
| ROCE | -42.8% | -42.8% | -38.8% | -33.9% | 42.7% | 34.6% | -46.7% | -58.9% | -60.7% | -34.1% |
Solvency and debt-coverage ratios — lower is generally safer
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.24 | 0.24 | 0.09 | 0.08 | 0.06 | 0.10 | 0.10 | 0.00 | — | — |
| Debt / EBITDA | — | — | — | — | 0.15 | 0.32 | — | — | — | — |
| Net Debt / Equity | — | -0.06 | -0.11 | -0.07 | -0.35 | -0.15 | -0.51 | -0.26 | — | — |
| Net Debt / EBITDA | — | — | — | — | -0.86 | -0.49 | — | — | — | — |
| Debt / FCF | — | — | — | — | -0.45 | — | — | — | — | — |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — |
Net cash position: cash ($234M) exceeds total debt ($187M)
Short-term solvency ratios and asset-utilisation metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.54 | 5.54 | 8.71 | 9.05 | 4.93 | 4.58 | 7.80 | 6.81 | 2.95 | 15.46 |
| Quick Ratio | 5.54 | 5.54 | 8.71 | 9.05 | 4.93 | 4.58 | 7.80 | 6.81 | 2.95 | 15.46 |
| Cash Ratio | 4.99 | 4.99 | 7.57 | 8.68 | 4.70 | 2.08 | 7.44 | 6.48 | 2.47 | 15.11 |
| Asset Turnover | — | 0.07 | 0.05 | 0.04 | 0.58 | 0.56 | 0.07 | 0.00 | 0.00 | 0.00 |
| Inventory Turnover | — | — | — | — | — | — | — | — | — | — |
| Days Sales Outstanding | — | 19.17 | — | — | — | 257.60 | — | — | — | — |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 |
|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | 15.1% | 9.5% | — | — | — | — |
| FCF Yield | — | — | — | — | 46.8% | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — | — |
| Shares Outstanding | — | $139M | $136M | $134M | $135M | $133M | $119M | $108M | $97M | $7M |
Clinical binary execution risk
Based on reported figures, Vir's price-to-sales ratio of 23.59x appears disconnected from its current clinical-stage reality, suggesting that the market continues to assign a premium to the company's legacy platform potential despite the total exhaustion of high-volume COVID-19 therapeutic revenue streams observed in recent quarters.
The elevated P/S multiple relative to peers like ADMA Biologics suggests investors are pricing in a speculative recovery rather than current fundamental performance. This valuation appears to rely heavily on the terminal value of the HBV pipeline, which remains unproven and highly sensitive to future clinical readouts.
As reported in financial statements, Vir's ROIC has remained consistently negative, bottoming out at -16.6% in 2025Q3, which highlights the company's ongoing struggle to generate meaningful returns on the capital deployed into its intensive R&D and laboratory operations during the post-pandemic transition period.
The negative ROIC trend indicates that the company is currently destroying shareholder value through its high-burn clinical development strategy. Without a successful commercial launch to drive positive operating income, this trend suggests that capital efficiency will remain constrained by the high fixed costs of its proprietary mAb platform.
According to recent SEC filings, Vir's asset turnover has remained near zero, reflecting a business model that has shifted away from physical product sales toward milestone-driven collaboration revenue, which inherently lacks the consistent inventory and receivable cycles found in traditional manufacturing or commercial-stage biotechnology firms.
The lack of meaningful asset turnover underscores the company's reliance on non-recurring inflows rather than a steady commercial engine. Investors should monitor whether the company can improve its capital velocity as it moves toward potential commercialization of its HBV assets, though current data suggests limited operational leverage.
Based on reported figures, Vir's current ratio has fluctuated significantly, reaching 7.11x in 2026Q1, yet this liquidity metric masks the underlying reality of a high cash-burn business model that requires constant capital replenishment to sustain its long-term clinical development pipeline and laboratory infrastructure.
While the current ratio appears healthy on the surface, it is largely a function of the company's remaining cash reserves being depleted by persistent operating losses. The lack of recurring revenue suggests that this liquidity position is temporary and may necessitate dilutive financing if milestone payments are delayed.
As indicated by financial disclosures, the price-to-sales ratio is a fundamentally flawed metric for Vir, as it obscures the non-recurring nature of milestone-based revenue and fails to account for the massive, inelastic R&D expenditures that define the company's true economic cost structure in the current period.
Analysts should instead focus on the cash runway and the probability-weighted net present value of the pipeline, as P/S ratios provide a misleading sense of stability for a company that lacks a recurring commercial product. Relying on revenue multiples in this context risks ignoring the binary nature of the company's clinical-stage assets.
Includes 30+ ratios · 9 years · Updated daily
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Quick answers to the most common questions about buying VIR stock.
Vir Biotechnology, Inc.'s current P/E ratio is -3.2x. The historical average is 8.6x.
Vir Biotechnology, Inc.'s return on equity (ROE) is -45.7%. The historical average is -33.4%.
Based on historical data, Vir Biotechnology, Inc. is trading at a P/E of -3.2x. Compare with industry peers and growth rates for a complete picture.
Vir Biotechnology, Inc. has 82.9% gross margin and -682.7% operating margin.