Negative free cash flow persists, with margins reaching -49.1% in 2024Q1, and a cash position of just $1.1 million as of 2025Q4 indicates a critical liquidity shortfall.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Aug'10 | Aug'09 | Aug'08 | Aug'07 | Aug'06 | Aug'05 | Aug'04 |
|---|
| Cash from Operations | -20.51M | -19.68M | -25.89M | -18.06M | -15.28M | -20.85M | -16.46M | -12.74M | -14.73M | -12.19M | -9.06M | -8.77M | -4.14M | -3.08M | -2.31M | -1.69M | -4.65K | -5.75K | 39.95K | -17.31K | -50K | 35 | -63 |
| Operating CF Margin % | - | -1139.49% | -2099.18% | -2329.8% | -4986.34% | -23162.01% | -122565.65% | -74517.17% | - | - | - | - | -28006.93% | - | -4210.78% | - | - | - | - | - | - | - | - |
| Operating CF Growth % | 18.54% | 23.98% | -43.35% | -18.23% | 26.74% | -26.66% | -29.24% | 13.53% | -20.83% | -34.65% | -3.3% | -111.7% | -34.26% | -33.25% | -37.28% | -36159.46% | 19.13% | -114.39% | 330.75% | 65.38% | -142954.29% | 155.56% | - |
| Net Income | -24.6M | -23.36M | -27.26M | -35.68M | -30.6M | -26.99M | -20.4M | -16.1M | -18.01M | -14.77M | -11.91M | -9.53M | -8.21M | -3.71M | -4.08M | -2.61M | -10.95K | -15.82K | -21.8K | -26.3K | -36.99K | -13.11K | -24.18K |
| Depreciation & Amortization | 1.16M | 1.22M | 1.34M | 1.41M | 1.19M | 1.15M | 1.04M | 902.41K | 636.38K | 528.17K | 309.41K | 236.34K | 142.13K | 146.4K | 135.74K | 118.62K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Stock-Based Compensation | 904.15K | 1.74M | 1.27M | 2.29M | 3.11M | 5.12M | 1.73M | 1.46M | 2.57M | 2.44M | 1.68M | 1.49M | 767.48K | 282.01K | 858.41K | 407.04K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 403 | 38.94K | 3.67K | -339.74K | 2.42M | 600.83K | 70K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 3.85M | 1.6M | 5.97K | -224.47K | 0 | 26.17K | -293.31K | 205.46K | 22.78K | 54.51K | -197.15K | -188.94K | 564.2K | -393.2K | 432.01K | 391.65K | 4.2K | 4.2K | 0 | 0 | 0 | 0 | 0 |
| Working Capital Changes | -1.72M | -885.8K | -1.25M | 14.14M | 11.02M | -156.11K | 1.46M | 793.12K | 45.94K | -480.74K | 1.05M | -437.07K | 178.79K | -9.96K | 272.3K | 5.1K | 2.1K | 5.87K | 61.75K | 8.98K | -13.01K | 13.14K | 24.12K |
| Change in Receivables | -63.24K | -207.23K | 132.04K | -169.67K | -72.61K | -12.51K | -7.12K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 559.61K | 77.98K | -1.22M | 1.22M | 548.61K | 522.22K | 2.05M | 1.11M | 65.84K | -339.66K | 1.09M | -315.78K | 281.86K | 34.7K | 305.65K | 0 | 2.1K | 5.87K | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | -95.79K | -89.56K | -573.85K | -1.08M | -1.57M | -973.56K | -1.65M | -511.27K | -301.81K | -1.43M | -415.09K | -352.24K | -302.99K | -714 | -90.69K | -34.87K | 0 | 0 | -40.97K | 0 | 0 | 0 | 0 |
| Capital Expenditures | -95.79K | -89.56K | -277.5K | -1.08M | -1.57M | -973.56K | -1.94M | -511.27K | -301.81K | -1.43M | -415.09K | -352.24K | -302.99K | -714 | -90.69K | -34.87K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| CapEx % of Revenue | 3.88% | 5.18% | 22.5% | 139.78% | 512.47% | 1081.31% | 14449.94% | 2990.56% | - | - | - | - | 2049.3% | - | 164.98% | - | - | - | - | - | - | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | -296.35K | 0 | 0 | 0 | 293.31K | 0 | 0 | 0 | 0 | -55K | 0 | 0 | 0 | 0 | 0 | 0 | -40.97K | 0 | 0 | 0 | 0 |
| Cash from Financing | 20.9M | 17.09M | 8.66M | 28.98M | 6.94M | 22.86M | 20.62M | 16.93M | 17.97M | 1.97M | 25.38M | 12.88M | 5.74M | 3.59M | 2.47M | 2.02M | 1.69K | 5.87K | 0 | 19.39K | 52.15K | 0 | 0 |
| Debt Issued (Net) | 7.07M | 6.02M | 233.23K | 827.08K | 209.28K | -221.51K | -296.34K | 344.99K | 585.54K | 1.01M | -77.77K | 223.15K | 0 | -54.4K | -102.56K | -289.44K | 1.69K | 5.87K | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 13.92M | 11.17M | 8.59M | 28.36M | 6.74M | 23.22M | 21.14M | 16.59M | 17.25M | 998.41K | 25.3M | 12.5M | 5.63M | 2.83M | 2.58M | 1.6M | 0 | 0 | 0 | 0 | 49.5K | 0 | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | -31.77K | 0 | 0 | -54.43K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -89.59K | -98.99K | -168.15K | -200.66K | -7.69K | -140.58K | -224.92K | -6.54K | 136.2K | -45.42K | 154.85K | 161.83K | 110.82K | 819.58K | 0 | 710.08K | 0 | 0 | 0 | 19.39K | 2.65K | 3.24K | 0 |
| Net Change in Cash | 502.48K | -2.15M | -17.47M | 9.86M | -9.71M | 1.14M | 2.48M | 3.54M | 3.31M | -11.56M | 15.76M | 3.78M | 1.25M | 512.28K | 28.53K | 300.41K | -2.96K | 123 | -1.02K | 2.08K | 2.15K | 35 | -63 |
| Free Cash Flow | -20.6M | -19.77M | -26.47M | -19.15M | -16.85M | -21.83M | -18.41M | -13.25M | -15.03M | -13.62M | -9.47M | -9.12M | -4.44M | -3.08M | -2.41M | -1.72M | -4.65K | -5.75K | 39.95K | -17.31K | -50K | 35 | -63 |
| FCF Margin % | -835.49% | -1144.67% | -2145.7% | -2469.59% | -5498.81% | -24243.33% | -137015.59% | -77507.73% | - | - | - | - | -30056.23% | - | -4375.76% | - | - | - | - | - | - | - | - |
| FCF Growth % | 7.8% | 25.29% | -38.23% | -13.64% | 22.81% | -18.59% | -38.9% | 11.87% | -10.4% | -43.79% | -3.86% | -105.2% | -44.05% | -28.26% | -39.77% | -36909.25% | 19.13% | -114.39% | 330.75% | 65.38% | -142954.29% | 155.56% | - |
| FCF per Share | -2.99 | -3.70 | -6.12 | -5.38 | -6.09 | -8.29 | -8.13 | -6.76 | -9.58 | -10.32 | -8.22 | -10.28 | -6.62 | -5.70 | -5.14 | -5.97 | -0.04 | -0.05 | 0.35 | -0.15 | -0.45 | 0.00 | -0.00 |
| FCF Conversion (FCF/Net Income) | 0.84x | 0.84x | 0.96x | 0.51x | 0.50x | 0.78x | 0.81x | 0.79x | 0.82x | 0.83x | 0.76x | 0.92x | 0.50x | 0.83x | 0.57x | 0.65x | 0.42x | 0.36x | -1.83x | 0.66x | 1.35x | -0.00x | 0.00x |
| Interest Paid | 123.36K | 0 | 340.36K | 221.62K | 173.11K | 155.8K | 129.8K | 126.85K | 110.92K | 73.13K | 20.38K | 7.33K | 10.54K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liquidity and dilution risk
According to the provided financial data, VNRX exhibits a persistent gap between net income and operating cash flow, with OCF/NI ratios frequently hovering near 1.00, indicating that reported losses are largely realized in cash rather than being mitigated by non-cash accounting adjustments or significant accrual benefits.
The tight correlation between net losses and operating cash outflows suggests that the company lacks the non-cash cushions, such as substantial depreciation or amortization, that typically soften the impact of R&D-heavy business models. Investors should interpret this as a sign that the company's cash burn is directly tied to its operational spending, leaving little room for error in its current clinical development trajectory.
As reported in quarterly filings, VNRX has consistently generated negative free cash flow, with margins reaching as low as -49.1% in 2024Q1, underscoring a structural inability to self-fund operations through current revenue streams while maintaining its aggressive clinical and research-based expansion strategy across multiple diagnostic verticals.
The absence of positive FCF generation suggests that the company remains entirely dependent on external financing to bridge the gap between its high operating costs and its nascent revenue base. This trajectory warrants close monitoring, as the lack of a clear path to cash flow breakeven increases the sensitivity of the equity to future capital market conditions.
Based on the reported figures, working capital changes have been highly erratic, swinging from a $14.4 million inflow in 2023Q4 to a $1.0 million outflow in 2025Q2, which suggests that cash flow is heavily influenced by the timing of milestone payments and lumpy accounts receivable collections.
Such volatility in working capital implies that the company's cash position is susceptible to the timing of partner-driven payments rather than steady-state operational efficiency. This lack of predictability in cash inflows may complicate management's ability to forecast liquidity needs, potentially leading to reactive and dilutive financing decisions.
Analysis of the cash flow statement reveals that stock-based compensation, which reached $812,000 in 2025Q2, serves as a critical non-cash expense that masks the true economic cost of talent acquisition, while minimal capitalized costs suggest that most R&D spending is expensed immediately rather than deferred on the balance sheet.
By expensing the majority of its R&D, the company provides a transparent, albeit painful, view of its cash burn, which avoids the potential for future asset impairment charges. However, the reliance on equity-based compensation to preserve cash highlights the company's limited liquidity and the ongoing pressure to manage its burn rate without further diluting existing shareholders.
Quick answers to the most common questions about buying VNRX stock.
VolitionRx Limited (VNRX) generated $-19.7M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
VolitionRx Limited (VNRX) reported negative free cash flow of $19.8M in 2025, indicating capital requirements exceeded cash from operations.
VolitionRx Limited (VNRX) spent $0.1M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.