Xilio Therapeutics, Inc. (XLO) Stock Price History
Historical prices from 2021 to 2026
- 1M
- -0.3%
- 3M
- -1.5%
- YTD
- -4.1%
- 1Y
- -19.6%
- 3Y
- -32.6%
- 5Y
- -47.4%
Loading 10-year price history...
XLO Historical Performance
XLO Annual Returns
Year-by-year price performance · 2021–2026
- 2021 annual price return
- +0.0%
- 2022 annual price return
- -83.2%
- 2023 annual price return
- -79.6%
- 2024 annual price return
- +66.1%
- 2025 annual price return
- -40.2%
- 2026 annual price return
- -3.1%
XLO Stock Price Trajectory (2021–2026)
As of October 3, 2026, Xilio Therapeutics, Inc. (XLO) trades at $9.01, representing a -19.6% return over the past year. The stock has delivered a -96.0% total return over five years (-47.4% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $391.30 on November 16, 2021. From this peak, XLO has corrected -97.7%, currently trading 5% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers NKTX (+17.6% 1Y), IMVT (+101.0% 1Y), and RCUS (+82.8% 1Y), XLO has underperformed the peer group average. Compare XLO vs NKTX →
XLO Historical Price Data · from 2021
Rows 1–50 of 1,241| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-10-02 | 9.08 | 9.13 | 8.89 | 9.01 | 7K | +1.12% |
| 2026-10-01 | 8.97 | 9.12 | 8.79 | 8.91 | 13K | -1.55% |
| 2026-09-30 | 9.20 | 9.25 | 9.05 | 9.05 | 5K | +1.26% |
| 2026-09-29 | 9.57 | 9.57 | 8.94 | 8.94 | 3K | -1.24% |
| 2026-09-28 | 8.99 | 9.22 | 8.96 | 9.05 | 11K | +0.11% |
| 2026-09-25 | 9.00 | 9.21 | 8.94 | 9.04 | 3K | +0.44% |
| 2026-09-24 | 8.93 | 9.09 | 8.93 | 9.00 | 16K | +0.67% |
| 2026-09-23 | 9.03 | 9.49 | 8.94 | 8.94 | 1K | -1.11% |
| 2026-09-22 | 9.04 | 9.16 | 8.95 | 9.04 | 7K | +0.22% |
| 2026-09-21 | 8.96 | 9.18 | 8.96 | 9.02 | 7K | -1.20% |
| 2026-09-18 | 9.08 | 9.34 | 8.94 | 9.13 | 23K | +1.00% |
| 2026-09-17 | 9.21 | 9.21 | 8.93 | 9.04 | 14K | +0.67% |
| 2026-09-16 | 8.95 | 9.02 | 8.93 | 8.98 | 12K | -0.55% |
| 2026-09-15 | 9.05 | 9.05 | 8.94 | 9.03 | 17K | +1.12% |
| 2026-09-14 | 8.99 | 9.21 | 8.93 | 8.93 | 10K | -2.88% |
| 2026-09-11 | 9.01 | 9.49 | 8.93 | 9.20 | 5K | +2.97% |
| 2026-09-10 | 9.11 | 9.11 | 8.93 | 8.93 | 11K | -0.45% |
| 2026-09-09 | 8.93 | 9.11 | 8.93 | 8.97 | 9K | +0.67% |
| 2026-09-08 | 8.98 | 9.12 | 8.81 | 8.91 | 10K | -1.00% |
| 2026-09-04 | 9.05 | 9.23 | 8.93 | 9.00 | 8K | -0.22% |
| 2026-09-03 | 8.94 | 9.05 | 8.72 | 9.02 | 7K | -0.22% |
| 2026-09-02 | 8.94 | 9.14 | 8.94 | 9.04 | 4K | +1.80% |
| 2026-09-01 | 8.57 | 9.25 | 8.57 | 8.88 | 31K | -4.21% |
| 2026-08-31 | 9.04 | 9.27 | 8.90 | 9.27 | 14K | +3.00% |
| 2026-08-28 | 9.05 | 9.10 | 9.00 | 9.00 | 4K | -0.11% |
| 2026-08-27 | 9.12 | 9.12 | 9.01 | 9.01 | 9K | -0.44% |
| 2026-08-26 | 9.09 | 9.14 | 8.85 | 9.05 | 8K | -0.33% |
| 2026-08-25 | 9.08 | 9.22 | 9.08 | 9.08 | 6K | -1.20% |
| 2026-08-24 | 9.32 | 9.32 | 9.17 | 9.19 | 2K | -0.43% |
| 2026-08-21 | 9.21 | 9.23 | 9.07 | 9.23 | 5K | 0.00% |
| 2026-08-20 | 9.27 | 9.27 | 9.11 | 9.23 | 6K | -1.91% |
| 2026-08-19 | 9.44 | 9.48 | 9.12 | 9.41 | 7K | -0.95% |
| 2026-08-18 | 9.50 | 9.65 | 9.21 | 9.50 | 13K | +0.11% |
| 2026-08-17 | 9.07 | 9.90 | 9.07 | 9.49 | 47K | +3.49% |
| 2026-08-14 | 9.14 | 9.27 | 8.68 | 9.17 | 8K | +1.78% |
| 2026-08-13 | 9.05 | 9.28 | 8.90 | 9.01 | 13K | -0.44% |
| 2026-08-12 | 9.18 | 9.18 | 8.78 | 9.05 | 9K | -1.42% |
| 2026-08-11 | 9.01 | 9.19 | 9.01 | 9.18 | 6K | -0.22% |
| 2026-08-10 | 8.80 | 9.25 | 8.80 | 9.20 | 7K | +0.33% |
| 2026-08-07 | 9.40 | 9.40 | 8.88 | 9.17 | 12K | -1.08% |
| 2026-08-06 | 9.11 | 9.62 | 9.02 | 9.27 | 34K | +1.76% |
| 2026-08-05 | 9.21 | 9.21 | 8.98 | 9.11 | 6K | +0.22% |
| 2026-08-04 | 9.17 | 9.24 | 8.98 | 9.09 | 21K | +0.44% |
| 2026-08-03 | 9.16 | 9.38 | 9.00 | 9.05 | 19K | -0.66% |
| 2026-07-31 | 9.00 | 9.16 | 8.89 | 9.11 | 11K | +0.33% |
| 2026-07-30 | 8.96 | 9.31 | 8.82 | 9.08 | 5K | -0.22% |
| 2026-07-29 | 9.23 | 9.23 | 9.00 | 9.10 | 12K | -0.55% |
| 2026-07-28 | 9.03 | 9.17 | 8.81 | 9.15 | 48K | +0.66% |
| 2026-07-27 | 8.65 | 9.19 | 8.44 | 9.09 | 38K | +5.09% |
| 2026-07-24 | 8.48 | 8.65 | 8.33 | 8.65 | 20K | +4.09% |
XLO Chart Terminal
Live VCP patterns, Cup & Handle overlays, support/resistance, and AI trade plans.
Live Breakouts Feed
High-probability breakout stocks crossing their pivot across 5 pattern engines.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
XLO — Frequently Asked Questions
Quick answers to the most common questions about buying XLO stock.
How has XLO stock performed recently?
XLO declined -19.6% over the past year, below its 5-year annualized CAGR of -47.4%. The stock trades above its 200-day moving average, reflecting the downtrend.
What is XLO's all-time high price?
Xilio Therapeutics, Inc. reached $391.30 on 2021-11-16. The 52-week high is $12.58. Current 1-year return of -19.6% places the stock further from historical peaks.
Where can I download XLO historical price data?
This page provides XLO daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2021-2026, downloadable in CSV format.