Xilio Therapeutics, Inc. (XLO) Stock Price History
Historical prices from 2021 to 2026
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XLO Historical Performance
Short-Term Returns
XLO Stock Price Trajectory (2021–2026)
As of May 8, 2026, Xilio Therapeutics, Inc. (XLO) trades at $7.81, representing a -16.3% return over the past year. The stock has delivered a -96.5% total return over five years (-48.9% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $391.30 on November 16, 2021. From this peak, XLO has corrected -98.0%, currently trading 17% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers NKTX (+68.4% 1Y), IMVT (+96.1% 1Y), and RCUS (+209.6% 1Y), XLO has underperformed the peer group average. Compare XLO vs NKTX →
XLO Historical Price Data (2025–2026)
Showing 30 of 1,140 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-07 | 7.99 | 7.99 | 7.80 | 7.81 | 7K | -1.14% |
| 2026-05-06 | 7.80 | 8.05 | 7.70 | 7.90 | 19K | +2.46% |
| 2026-05-05 | 8.33 | 8.65 | 7.47 | 7.71 | 69K | -9.72% |
| 2026-05-04 | 8.31 | 8.66 | 8.30 | 8.54 | 38K | +2.64% |
| 2026-05-01 | 7.84 | 8.50 | 7.77 | 8.32 | 49K | +5.05% |
| 2026-04-30 | 7.91 | 8.02 | 7.75 | 7.92 | 25K | +1.67% |
| 2026-04-29 | 7.69 | 8.16 | 7.57 | 7.79 | 31K | -1.64% |
| 2026-04-28 | 8.25 | 8.27 | 7.84 | 7.92 | 34K | -3.18% |
| 2026-04-27 | 8.32 | 8.56 | 8.10 | 8.18 | 32K | -1.56% |
| 2026-04-24 | 8.30 | 8.51 | 8.20 | 8.31 | 33K | -1.89% |
| 2026-04-23 | 8.67 | 8.67 | 8.39 | 8.47 | 28K | -1.51% |
| 2026-04-22 | 8.66 | 8.66 | 8.40 | 8.60 | 22K | +0.94% |
| 2026-04-21 | 8.45 | 8.57 | 8.38 | 8.52 | 27K | +0.83% |
| 2026-04-20 | 8.62 | 8.63 | 8.27 | 8.45 | 68K | -1.40% |
| 2026-04-17 | 8.61 | 8.76 | 8.31 | 8.57 | 38K | +2.63% |
| 2026-04-16 | 8.31 | 8.77 | 8.19 | 8.35 | 23K | -3.02% |
| 2026-04-15 | 8.57 | 8.74 | 8.33 | 8.61 | 35K | +0.23% |
| 2026-04-14 | 8.67 | 8.67 | 8.32 | 8.59 | 26K | +1.54% |
| 2026-04-13 | 8.50 | 8.90 | 8.41 | 8.46 | 21K | -0.59% |
| 2026-04-10 | 8.52 | 8.81 | 8.47 | 8.51 | 13K | -0.58% |
| 2026-04-09 | 8.68 | 8.68 | 8.55 | 8.56 | 10K | -1.50% |
| 2026-04-08 | 8.99 | 8.99 | 8.46 | 8.69 | 61K | +2.24% |
| 2026-04-07 | 8.43 | 8.73 | 8.20 | 8.50 | 31K | +0.47% |
| 2026-04-06 | 8.50 | 9.20 | 8.44 | 8.46 | 28K | -0.59% |
| 2026-04-02 | 8.30 | 8.57 | 8.20 | 8.51 | 26K | +0.35% |
| 2026-04-01 | 8.54 | 8.80 | 8.46 | 8.48 | 46K | +0.83% |
| 2026-03-31 | 8.33 | 8.88 | 8.33 | 8.41 | 73K | +2.06% |
| 2026-03-30 | 8.48 | 8.51 | 8.02 | 8.24 | 14K | -0.96% |
| 2026-03-27 | 8.57 | 8.79 | 8.30 | 8.32 | 25K | -4.15% |
| 2026-03-26 | 8.62 | 9.25 | 8.41 | 8.68 | 59K | +1.76% |
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Start ComparisonXLO — Frequently Asked Questions
Quick answers to the most common questions about buying XLO stock.
How has XLO stock performed recently?
XLO declined -16.3% over the past year, below its 5-year annualized CAGR of -48.9%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is XLO's all-time high price?
Xilio Therapeutics, Inc. reached $391.30 on 2021-11-16. The 52-week high is $16.52. Current 1-year return of -16.3% places the stock further from historical peaks.
Where can I download XLO historical price data?
This page provides XLO daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2021-2026, downloadable in CSV format.