Xilio Therapeutics, Inc. (XLO) Stock Price History
Historical prices from 2021 to 2026
- 1M
- +8.4%
- 3M
- +4.3%
- YTD
- -3.7%
- 1Y
- -4.8%
- 3Y
- -37.9%
- 5Y
- -47.4%
Loading 10-year price history...
XLO Historical Performance
XLO Annual Returns
Year-by-year price performance · 2021–2026
- 2021 annual price return
- +0.0%
- 2022 annual price return
- -83.2%
- 2023 annual price return
- -79.6%
- 2024 annual price return
- +66.1%
- 2025 annual price return
- -40.2%
- 2026 annual price return
- -21.4%
XLO Stock Price Trajectory (2021–2026)
As of June 28, 2026, Xilio Therapeutics, Inc. (XLO) trades at $9.05, representing a -4.8% return over the past year. The stock has delivered a -96.0% total return over five years (-47.4% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $391.30 on November 16, 2021. From this peak, XLO has corrected -97.7%, currently trading 1% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers NKTX (+63.6% 1Y), IMVT (+137.0% 1Y), and RCUS (+264.7% 1Y), XLO has underperformed the peer group average. Compare XLO vs NKTX →
XLO Historical Price Data · from 2021
Rows 1–50 of 1,174| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-26 | 8.50 | 9.07 | 8.50 | 9.05 | 44K | +3.43% |
| 2026-06-25 | 9.00 | 9.02 | 8.71 | 8.75 | 9K | -2.89% |
| 2026-06-24 | 8.94 | 9.09 | 8.91 | 9.01 | 18K | +1.24% |
| 2026-06-23 | 9.18 | 9.19 | 8.84 | 8.90 | 31K | -0.45% |
| 2026-06-22 | 8.88 | 9.05 | 8.83 | 8.94 | 26K | +1.71% |
| 2026-06-18 | 8.96 | 9.21 | 7.82 | 8.79 | 57K | +0.46% |
| 2026-06-17 | 8.31 | 8.87 | 8.28 | 8.75 | 99K | +6.06% |
| 2026-06-16 | 8.22 | 8.50 | 8.06 | 8.25 | 15K | -1.08% |
| 2026-06-15 | 7.99 | 8.55 | 7.99 | 8.34 | 6K | +2.71% |
| 2026-06-12 | 8.00 | 8.31 | 7.90 | 8.12 | 12K | +1.63% |
| 2026-06-11 | 7.95 | 7.99 | 7.70 | 7.99 | 7K | +1.14% |
| 2026-06-10 | 8.09 | 8.09 | 7.79 | 7.90 | 11K | 0.00% |
| 2026-06-09 | 7.62 | 7.90 | 7.56 | 7.90 | 37K | +2.86% |
| 2026-06-08 | 7.80 | 8.33 | 7.60 | 7.68 | 22K | -0.26% |
| 2026-06-05 | 8.14 | 8.27 | 7.53 | 7.70 | 47K | -7.34% |
| 2026-06-04 | 8.23 | 8.32 | 8.08 | 8.31 | 7K | +2.03% |
| 2026-06-03 | 8.12 | 8.33 | 8.10 | 8.14 | 9K | -0.67% |
| 2026-06-02 | 8.34 | 8.39 | 8.18 | 8.20 | 27K | -0.61% |
| 2026-06-01 | 8.43 | 8.53 | 8.20 | 8.25 | 21K | -2.48% |
| 2026-05-29 | 8.47 | 8.50 | 8.09 | 8.46 | 27K | -0.70% |
| 2026-05-28 | 8.38 | 8.62 | 8.17 | 8.52 | 27K | +2.16% |
| 2026-05-27 | 8.46 | 8.46 | 8.29 | 8.34 | 22K | -0.12% |
| 2026-05-26 | 8.31 | 8.56 | 8.29 | 8.35 | 22K | +1.21% |
| 2026-05-22 | 8.40 | 8.60 | 8.17 | 8.25 | 0 | -3.79% |
| 2026-05-21 | 8.39 | 8.61 | 8.30 | 8.57 | 16K | +3.94% |
| 2026-05-20 | 8.00 | 8.33 | 7.97 | 8.25 | 25K | +0.86% |
| 2026-05-19 | 8.22 | 8.29 | 8.03 | 8.18 | 24K | +1.74% |
| 2026-05-18 | 8.19 | 8.54 | 8.02 | 8.04 | 51K | -3.83% |
| 2026-05-15 | 8.80 | 8.81 | 8.34 | 8.36 | 37K | -5.11% |
| 2026-05-14 | 7.74 | 9.00 | 7.74 | 8.81 | 723K | +13.53% |
| 2026-05-13 | 7.82 | 7.93 | 7.75 | 7.76 | 23K | +0.39% |
| 2026-05-12 | 7.73 | 7.92 | 7.67 | 7.73 | 26K | 0.00% |
| 2026-05-11 | 7.82 | 7.82 | 7.72 | 7.73 | 20K | -0.13% |
| 2026-05-08 | 7.83 | 7.91 | 7.73 | 7.74 | 23K | -0.90% |
| 2026-05-07 | 7.99 | 7.99 | 7.80 | 7.81 | 7K | -1.14% |
| 2026-05-06 | 7.80 | 8.05 | 7.70 | 7.90 | 19K | +2.46% |
| 2026-05-05 | 8.33 | 8.65 | 7.47 | 7.71 | 69K | -9.72% |
| 2026-05-04 | 8.31 | 8.66 | 8.30 | 8.54 | 38K | +2.64% |
| 2026-05-01 | 7.84 | 8.50 | 7.77 | 8.32 | 49K | +5.05% |
| 2026-04-30 | 7.91 | 8.02 | 7.75 | 7.92 | 25K | +1.67% |
| 2026-04-29 | 7.69 | 8.16 | 7.57 | 7.79 | 31K | -1.64% |
| 2026-04-28 | 8.25 | 8.27 | 7.84 | 7.92 | 34K | -3.18% |
| 2026-04-27 | 8.32 | 8.56 | 8.10 | 8.18 | 32K | -1.56% |
| 2026-04-24 | 8.30 | 8.51 | 8.20 | 8.31 | 33K | -1.89% |
| 2026-04-23 | 8.67 | 8.67 | 8.39 | 8.47 | 28K | -1.51% |
| 2026-04-22 | 8.66 | 8.66 | 8.40 | 8.60 | 22K | +0.94% |
| 2026-04-21 | 8.45 | 8.57 | 8.38 | 8.52 | 27K | +0.83% |
| 2026-04-20 | 8.62 | 8.63 | 8.27 | 8.45 | 68K | -1.40% |
| 2026-04-17 | 8.61 | 8.76 | 8.31 | 8.57 | 38K | +2.63% |
| 2026-04-16 | 8.31 | 8.77 | 8.19 | 8.35 | 23K | -3.02% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
XLO — Frequently Asked Questions
Quick answers to the most common questions about buying XLO stock.
How has XLO stock performed recently?
XLO declined -4.8% over the past year, below its 5-year annualized CAGR of -47.4%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is XLO's all-time high price?
Xilio Therapeutics, Inc. reached $391.30 on 2021-11-16. The 52-week high is $12.74. Current 1-year return of -4.8% places the stock further from historical peaks.
Where can I download XLO historical price data?
This page provides XLO daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2021-2026, downloadable in CSV format.