ProQR Therapeutics N.V. (PRQR) Total Return Calculator with Dividends Reinvested

ProQR Therapeutics N.V.

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The total return for ProQR Therapeutics N.V. (PRQR) stock is -20.88% over the past 12 months. So far it's down 27.64% this year. The 5-year total return is -78.70%, meaning $10,000 invested in PRQR stock 5 years ago would be worth $2,130 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in PRQR 1 year ago, it would be worth $7,423 today — you'd have lost $2,577.

With Dividends Reinvested$7,423-25.77%

Price Only (No DRIP)$7,423-25.77%

Period2025-06-12 → 2026-06-12

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in PRQR

1Y$7,912-$2,088 (-20.9%)-20.9% CAGR

3Y$8,727-$1,273 (-12.7%)-4.4% CAGR

5Y$2,130-$7,870 (-78.7%)-26.6% CAGR

10Y$3,179-$6,821 (-68.2%)-10.8% CAGR

15Y$978-$9,022 (-90.2%)-14.4% CAGR

20Y$978-$9,022 (-90.2%)-11.0% CAGR

30Y$978-$9,022 (-90.2%)-7.5% CAGR

ProQR Therapeutics N.V. did not pay dividends during this period. Total return = price return.

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As of 2026-06-12

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-27.64%	—	-27.64%	—	$7,236
1Y	-20.88%	-20.88%	-25.77%	+4.89 pp	$7,912
3Y	-12.73%	-4.44%	-12.73%	—	$8,727
5Y	-78.70%	-26.60%	-80.62%	+1.92 pp	$2,130
10Y	-68.21%	-10.83%	-68.21%	—	$3,179
15Y	-90.22%	-14.36%	-90.22%	—	$978
20Y	-90.22%	-10.98%	-90.22%	—	$978
30Y	-90.22%	-7.46%	-90.22%	—	$978

Risk & Highlights

Best Year+378.18%2018

Worst Year-57.58%2020

Max Drawdown-55.08%2025-10-20 → 2026-03-27

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-20.10%	-20.10%	—	+0.41%	-20.5pp
2025	-26.28%	-26.28%	—	+16.64%	-42.9pp
2024	+27.40%	+27.40%	—	+24.00%	+3.4pp
2023	-41.94%	-41.94%	—	+24.81%	-66.7pp
2022	-54.21%	-54.21%	—	-19.95%	-34.3pp

PRQR underperformed the S&P 500 by 43.56pp over the past year (-20.88% vs +22.68%).

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PRQR Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
PRQRProQR Therapeutics N.V.	$152M	-10.0%	-27.6%	-20.9%	—	-12.7%	-78.7%	-68.2%
EDITEditas Medicine, Inc.	$245M	-14.7%	+19.0%	+20.2%	—	-75.4%	-93.5%	-91.9%
NTLAIntellia Therapeutics, Inc.	$1.4B	-13.4%	+34.1%	+47.6%	—	-71.7%	-85.5%	-53.6%
CRSPCRISPR Therapeutics AG	$4.8B	-5.7%	-6.6%	+21.0%	—	-16.1%	-60.4%	+256.5%
BEAMBeam Therapeutics Inc.	$3.0B	-8.1%	+8.4%	+64.4%	—	-10.8%	-66.9%	+56.9%
ARWRArrowhead Pharmaceuticals, Inc.	$10.5B	-5.7%	+9.8%	+344.5%	—	+110.3%	-16.1%	+1167.6%
QUREuniQure N.V.	$1.7B	-5.3%	+14.7%	+65.4%	—	+39.6%	-25.6%	+170.6%
RCKTRocket Pharmaceuticals, Inc.	$300M	-24.5%	-23.1%	-12.2%	—	-88.4%	-94.2%	-91.4%
REPLReplimune Group, Inc.	$733M	+117.1%	-3.1%	-11.9%	—	-63.2%	-74.6%	-43.1%
SLDBSolid Biosciences Inc.	$556M	-7.5%	+32.5%	+56.6%	—	+14.6%	-88.3%	-97.9%
RAREUltragenyx Pharmaceutical Inc.	$2.4B	-9.3%	+1.6%	-36.1%	—	-53.3%	-76.4%	-60.0%

Compare:PRQR vs EDIT PRQR vs NTLA PRQR vs CRSP PRQR vs EDIT vs NTLA

About PRQR Dividend Returns

ProQR Therapeutics N.V. (PRQR) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of PRQR over the past year?

ProQR Therapeutics N.V. (PRQR) delivered a return of -20.88% over the past year. Since PRQR does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in PRQR be worth today?

A $10,000 investment in ProQR Therapeutics N.V. one year ago would be worth $7,912 today, representing a loss of $2,088.

Q3Does PRQR pay dividends?

ProQR Therapeutics N.V. (PRQR) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For PRQR, the total return equals the price-only return.

Q4Did PRQR beat the S&P 500?

No, ProQR Therapeutics N.V. (PRQR) underperformed the S&P 500 by 43.56 percentage points over the past year. PRQR delivered a total return of -20.88%, compared to the S&P 500's 22.68%. This means a passive S&P 500 index fund outperformed PRQR by 43.56pp during this period.

Q5What is PRQR's worst drawdown?

ProQR Therapeutics N.V. (PRQR) experienced a maximum drawdown of -55.08% over the past year, declining from its peak on 2025-10-20 to its trough on 2026-03-27. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is PRQR's long-term total return over 10, 20, or 30 years?

Here are ProQR Therapeutics N.V. (PRQR)'s long-term returns with dividends reinvested. Over 10 years, the total return is -68.2% (-10.8% CAGR) — $10,000 would have grown to $3,179. Over 20 years: -90.2% total return (-11.0% CAGR) — $10,000 → $978. Over 30 years: -90.2% total return (-7.5% CAGR) — $10,000 → $978. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was PRQR's best and worst year?

ProQR Therapeutics N.V.'s best calendar year was 2018 with a total return of 378.2%. Its worst year was 2020 with a total return of -57.6%. This range shows the volatility investors should expect — the difference between the best and worst year is 435.8 percentage points.

How much would $100/month in PRQR be worth today?

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