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Plus Therapeutics, Inc. (PSTV) Total Return Calculator with Dividends Reinvested

Plus Therapeutics, Inc.

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The total return for Plus Therapeutics, Inc. (PSTV) stock is -52.00% over the past 12 months. So far it's down 56.77% this year. The 5-year total return is -99.29%, meaning $10,000 invested in PSTV stock 5 years ago would be worth $71 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in PSTV 1 year ago, it would be worth $4,258 today — you'd have lost $5,742.

With Dividends Reinvested$4,258-57.42%

Price Only (No DRIP)$4,258-57.42%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in PSTV

1Y$4,800-$5,200 (-52.0%)-52.0% CAGR

3Y$570-$9,430 (-94.3%)-61.5% CAGR

5Y$71-$9,929 (-99.3%)-62.8% CAGR

10Y$0-$10,000 (-100.0%)-68.7% CAGR

15Y$0-$10,000 (-100.0%)-55.1% CAGR

20Y$0-$10,000 (-100.0%)-45.2% CAGR

30Y$0-$10,000 (-100.0%)-33.0% CAGR

Plus Therapeutics, Inc. did not pay dividends during this period. Total return = price return.

Loading PSTV total return...

As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-56.77%	—	-56.77%	—	$4,323
1Y	-52.00%	-52.00%	-52.00%	—	$4,800
3Y	-94.30%	-61.51%	-94.30%	—	$570
5Y	-99.29%	-62.85%	-99.29%	—	$71
10Y	-100.00%	-68.71%	-100.00%	—	$0
15Y	-100.00%	-55.14%	-100.00%	—	$0
20Y	-100.00%	-45.18%	-100.00%	—	$0
30Y	-100.00%	-33.02%	-100.00%	—	$0

Risk & Highlights

Best Year+248.74%2005

Worst Year-90.00%2018

Max Drawdown-98.78%2025-10-06 → 2026-01-24

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-45.95%	-45.95%	—	+0.41%	-46.4pp
2025	-56.78%	-56.78%	—	+16.64%	-73.4pp
2024	-37.84%	-37.84%	—	+24.00%	-61.8pp
2023	-62.37%	-62.37%	—	+24.81%	-87.2pp
2022	-70.64%	-70.64%	—	-19.95%	-50.7pp

PSTV underperformed the S&P 500 by 83.32pp over the past year (-52.00% vs +31.32%).

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PSTV Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
PSTVPlus Therapeutics, Inc.	$15M	+80.2%	-56.8%	-52.0%	—	-94.3%	-99.3%	-100.0%
NRXPNRx Pharmaceuticals, Inc.	$84M	+35.6%	+16.4%	+58.9%	—	-50.8%	-99.0%	-96.8%
AGENAgenus Inc.	$137M	+3.2%	+20.4%	+31.0%	—	-87.8%	-93.1%	-93.5%
CLDXCelldex Therapeutics, Inc.	$2.3B	+9.6%	+27.3%	+86.9%	—	+3.1%	+29.4%	-34.3%
IARTIntegra LifeSciences Holdings Corporation	$1.1B	+50.4%	+16.6%	+9.8%	—	-72.2%	-81.0%	-61.1%
ACTGAcacia Research Corporation	$489M	+1.0%	+35.6%	+64.6%	—	+29.0%	-14.1%	+9.5%
NVCRNovoCure Limited	$1.9B	+56.4%	+25.7%	+1.0%	—	-76.2%	-91.5%	+31.0%
ARAYAccuray Incorporated	$58M	+17.5%	-42.1%	-62.1%	—	-86.3%	-89.1%	-90.3%
BNGOBionano Genomics, Inc.	$14M	+10.4%	-20.1%	-65.7%	—	-99.7%	-100.0%	-97.9%
NVSNovartis AG	$283.1B	-2.9%	+10.5%	+38.5%	+4.3pp	+61.5%	+99.3%	+188.8%
ISRGIntuitive Surgical, Inc.	$160.4B	-0.2%	-19.6%	-14.8%	—	+49.0%	+60.9%	+556.9%

Compare:PSTV vs NRXP PSTV vs AGEN PSTV vs CLDX PSTV vs NRXP vs AGEN

About PSTV Dividend Returns

Plus Therapeutics, Inc. (PSTV) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of PSTV over the past year?

Plus Therapeutics, Inc. (PSTV) delivered a return of -52.00% over the past year. Since PSTV does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in PSTV be worth today?

A $10,000 investment in Plus Therapeutics, Inc. one year ago would be worth $4,800 today, representing a loss of $5,200.

Q3Does PSTV pay dividends?

Plus Therapeutics, Inc. (PSTV) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For PSTV, the total return equals the price-only return.

Q4Did PSTV beat the S&P 500?

No, Plus Therapeutics, Inc. (PSTV) underperformed the S&P 500 by 83.32 percentage points over the past year. PSTV delivered a total return of -52.00%, compared to the S&P 500's 31.32%. This means a passive S&P 500 index fund outperformed PSTV by 83.32pp during this period.

Q5What is PSTV's worst drawdown?

Plus Therapeutics, Inc. (PSTV) experienced a maximum drawdown of -98.78% over the past year, declining from its peak on 2025-10-06 to its trough on 2026-01-24. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is PSTV's long-term total return over 10, 20, or 30 years?

Here are Plus Therapeutics, Inc. (PSTV)'s long-term returns with dividends reinvested. Over 10 years, the total return is -100.0% (-68.7% CAGR) — $10,000 would have grown to $0. Over 20 years: -100.0% total return (-45.2% CAGR) — $10,000 → $0. Over 30 years: -100.0% total return (-33.0% CAGR) — $10,000 → $0. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was PSTV's best and worst year?

Plus Therapeutics, Inc.'s best calendar year was 2005 with a total return of 248.7%. Its worst year was 2018 with a total return of -90.0%. This range shows the volatility investors should expect — the difference between the best and worst year is 338.7 percentage points.