Lyell Immunopharma, Inc. (LYEL)
Estimates & Forecasts•Proprietary EPS, revenue & margin forecasts — FY+1 to FY+4
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LYEL Price Targets Summary| Metric | 2023 | 2024 | 2025 |
|---|---|---|---|
| Net Income | $-235M | $-343M | $-274M |
| EPS (Diluted) | $-0.93 | $-1.31 | $-16.06 |
| YoY Growth | — | — | — |
| Net Margin | -180486.2% | -562285.2% | -762355.6% |
USD · LYEL · Proprietary Model| Metric | 2025A | 2026E | 2027E | 2028E | 2029E |
|---|---|---|---|---|---|
| Revenue | $36,000 | $20,495 | $297,123 | $13,354 | $12,495 |
| Net Income | $-274M | $-29M | $-36M | $-6,677 | $-6,247.5 |
| EPS (Diluted) | $-16.06 | $-1.13 | $-1.27 | $-0.00 | $-0.00 |
| Free Cash Flow | $-151M | $-6,148 | $-89,136 | $-4,006 | $-3,748 |
Treat point estimates cautiously; use wider scenario ranges and position sizing discipline.
Quick answers to the most common questions about buying LYEL stock.
Lyell Immunopharma, Inc.'s projected EPS for the next fiscal year is $-1.13. This estimate blends our quantitative model with Wall Street analyst consensus and carries a confidence score of 25/100. The model factors in revenue trajectory, margin path, and share buyback trends to arrive at this figure.
Our scenario-based model produces three price targets for Lyell Immunopharma, Inc.: Bear case $N/A, Base case $N/A, and Bull case $N/A. These targets are derived by applying the median historical P/E ratio to forward EPS estimates under each growth scenario. They are not buy/sell recommendations.
Lyell Immunopharma, Inc.'s projected revenue growth for the next fiscal year is -33.9%, reaching approximately $0.0B in total revenue. Growth estimates are probability-weighted and blend analyst consensus with our CAGR extrapolation model. Outer years (FY+3, FY+4) fade toward industry median growth rates.
Accuracy depends on several measurable factors. Our model confidence score of 25/100 is computed from revenue predictability (25% weight), margin stability (20%), historical earnings beat rate (20%), data depth (15%), analyst coverage (10%), and model-consensus agreement (10%). Contracting margins add uncertainty to forward projections. No forecast model is perfect — always cross-reference with your own analysis.
Lyell Immunopharma, Inc.'s forward operating margin is estimated at -50.0% for the next fiscal year. The margin trend is currently "contracting". Our model tracks margin mean-reversion patterns and adjusts for sector-specific cost dynamics. Operating leverage is a key driver of EPS growth beyond top-line revenue expansion.
The v2 model uses a multi-step process: (1) Revenue is projected via blended CAGR with probability weighting, (2) Operating and net margins follow a mean-reversion path calibrated to sector norms, (3) EPS is derived from net income divided by projected diluted shares (accounting for buyback trends), (4) For FY+1 and FY+2, estimates are blended with analyst consensus based on coverage depth, (5) Price targets apply median historical P/E to forward EPS under bear/base/bull growth scenarios. All inputs are from public filings and third-party data providers.
The bear case ($N/A) assumes P25 revenue growth, worst-case margins, and multiple compression. Key risks include: unexpected margin contraction, revenue deceleration below model floor, regulatory headwinds, macro deterioration, or competitive disruption. A confidence score below 60 suggests higher estimate volatility. Always size positions according to the full scenario range, not just the base case.
Our model is above Wall Street consensus with a 85.0% gap. For FY+1, analyst estimates blend with our model at 15% analyst weight. By FY+3 and FY+4, estimates are purely model-driven as analyst coverage thins out at longer horizons.