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AAPG vs ARVN vs KYMR vs BMY
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - General
AAPG vs ARVN vs KYMR vs BMY — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General |
| Market Cap | $6.55B | $652M | $6.91B | $114.85B |
| Revenue (TTM) | $1.29B | $263M | $51M | $48.48B |
| Net Income (TTM) | $-1.52B | $-81M | $-315M | $7.28B |
| Gross Margin | 95.1% | 99.5% | 33.2% | 68.7% |
| Operating Margin | -113.2% | -44.0% | -7.0% | 25.7% |
| Forward P/E | — | — | — | 8.9x |
| Total Debt | $1.67B | $9M | $82M | $47.14B |
| Cash & Equiv. | $1.24B | $143M | $357M | $10.21B |
AAPG vs ARVN vs KYMR vs BMY — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jan 25 | May 26 | Return |
|---|---|---|---|
| ASCENTAGE PHARMA GR… (AAPG) | 100 | 122.7 | +22.7% |
| Arvinas, Inc. (ARVN) | 100 | 57.9 | -42.1% |
| Kymera Therapeutics… (KYMR) | 100 | 213.8 | +113.8% |
| Bristol-Myers Squib… (BMY) | 100 | 95.4 | -4.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AAPG vs ARVN vs KYMR vs BMY
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AAPG is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 341.8%, EPS growth 89.8%, 3Y rev CAGR 227.5%
- 341.8% revenue growth vs KYMR's -16.7%
ARVN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.15, Low D/E 2.0%, current ratio 4.92x
KYMR is the clearest fit if your priority is long-term compounding.
- 154.4% 10Y total return vs AAPG's 24.9%
- +190.7% vs AAPG's -10.2%
BMY carries the broadest edge in this set and is the clearest fit for income & stability and defensive.
- Dividend streak 6 yrs, beta 0.50, yield 4.4%
- Beta 0.50, yield 4.4%, current ratio 1.26x
- 15.0% margin vs KYMR's -6.1%
- Beta 0.50 vs KYMR's 1.15
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 341.8% revenue growth vs KYMR's -16.7% | |
| Quality / Margins | 15.0% margin vs KYMR's -6.1% | |
| Stability / Safety | Beta 0.50 vs KYMR's 1.15 | |
| Dividends | 4.4% yield; 6-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +190.7% vs AAPG's -10.2% | |
| Efficiency (ROA) | 7.9% ROA vs AAPG's -49.9%, ROIC 16.9% vs -36.9% |
AAPG vs ARVN vs KYMR vs BMY — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
AAPG vs ARVN vs KYMR vs BMY — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BMY leads in 3 of 6 categories
KYMR leads 1 • AAPG leads 0 • ARVN leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
BMY leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BMY is the larger business by revenue, generating $48.5B annually — 942.0x KYMR's $51M. BMY is the more profitable business, keeping 15.0% of every revenue dollar as net income compared to KYMR's -6.1%. On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $1.3B | $263M | $51M | $48.5B |
| EBITDAEarnings before interest/tax | -$1.3B | -$111M | -$352M | $15.7B |
| Net IncomeAfter-tax profit | -$1.5B | -$81M | -$315M | $7.3B |
| Free Cash FlowCash after capex | -$505M | -$276M | -$244M | $11.9B |
| Gross MarginGross profit ÷ Revenue | +95.1% | +99.5% | +33.2% | +68.7% |
| Operating MarginEBIT ÷ Revenue | -113.2% | -44.0% | -7.0% | +25.7% |
| Net MarginNet income ÷ Revenue | -117.5% | -30.8% | -6.1% | +15.0% |
| FCF MarginFCF ÷ Revenue | -39.1% | -105.0% | -4.7% | +24.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | -71.6% | -84.0% | +55.5% | +2.6% |
| EPS Growth (YoY)Latest quarter vs prior year | -4.1% | -65.1% | +13.4% | +9.2% |
Valuation Metrics
Evenly matched — AAPG and ARVN and BMY each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $6.6B | $652M | $6.9B | $114.8B |
| Enterprise ValueMkt cap + debt − cash | $6.6B | $517M | $6.6B | $151.8B |
| Trailing P/EPrice ÷ TTM EPS | -110.21x | -7.96x | -22.93x | 16.30x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 8.93x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 9.17x |
| Price / SalesMarket cap ÷ Revenue | 45.49x | 2.48x | 176.26x | 2.38x |
| Price / BookPrice ÷ Book value/share | 162.71x | 1.52x | 4.52x | 6.20x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 8.94x |
Profitability & Efficiency
BMY leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
BMY delivers a 39.0% return on equity — every $100 of shareholder capital generates $39 in annual profit, vs $-2 for AAPG. ARVN carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to AAPG's 6.09x. On the Piotroski fundamental quality scale (0–9), BMY scores 8/9 vs KYMR's 4/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -2.2% | -14.3% | -25.0% | +39.0% |
| ROA (TTM)Return on assets | -49.9% | -9.3% | -22.3% | +7.9% |
| ROICReturn on invested capital | -36.9% | -22.4% | -24.9% | +16.9% |
| ROCEReturn on capital employed | -24.5% | -16.0% | -27.2% | +18.7% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 4 | 8 |
| Debt / EquityFinancial leverage | 6.09x | 0.02x | 0.05x | 2.55x |
| Net DebtTotal debt minus cash | $432M | -$134M | -$275M | $36.9B |
| Cash & Equiv.Liquid assets | $1.2B | $143M | $357M | $10.2B |
| Total DebtShort + long-term debt | $1.7B | $9M | $82M | $47.1B |
| Interest CoverageEBIT ÷ Interest expense | -30.31x | — | -2119.53x | 10.33x |
Total Returns (Dividends Reinvested)
KYMR leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in KYMR five years ago would be worth $19,212 today (with dividends reinvested), compared to $1,601 for ARVN. Over the past 12 months, KYMR leads with a +190.7% total return vs AAPG's -10.2%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs ARVN's -25.5% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -17.7% | -11.2% | +16.3% | +7.6% |
| 1-Year ReturnPast 12 months | -10.2% | +52.8% | +190.7% | +23.4% |
| 3-Year ReturnCumulative with dividends | +24.9% | -58.7% | +205.1% | -7.1% |
| 5-Year ReturnCumulative with dividends | +24.9% | -84.0% | +92.1% | +5.2% |
| 10-Year ReturnCumulative with dividends | +24.9% | -36.5% | +154.4% | +6.7% |
| CAGR (3Y)Annualised 3-year return | +7.7% | -25.5% | +45.0% | -2.4% |
Risk & Volatility
BMY leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
BMY is the less volatile stock with a 0.50 beta — it tends to amplify market swings less than KYMR's 1.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BMY currently trades 89.4% from its 52-week high vs AAPG's 44.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.85x | 1.15x | 1.15x | 0.50x |
| 52-Week HighHighest price in past year | $48.45 | $14.51 | $103.00 | $62.89 |
| 52-Week LowLowest price in past year | $20.06 | $5.90 | $28.06 | $42.52 |
| % of 52W HighCurrent price vs 52-week peak | +44.8% | +70.2% | +82.2% | +89.4% |
| RSI (14)Momentum oscillator 0–100 | 37.5 | 42.6 | 54.1 | 41.4 |
| Avg Volume (50D)Average daily shares traded | 3K | 808K | 602K | 10.3M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: AAPG as "Buy", ARVN as "Buy", KYMR as "Buy", BMY as "Hold". Consensus price targets imply 112.0% upside for AAPG (target: $46) vs 10.2% for BMY (target: $62). BMY is the only dividend payer here at 4.39% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | $46.00 | $13.00 | $117.06 | $62.00 |
| # AnalystsCovering analysts | 1 | 26 | 26 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +4.4% |
| Dividend StreakConsecutive years of raises | — | — | — | 6 |
| Dividend / ShareAnnual DPS | — | — | — | $2.47 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +14.1% | 0.0% | 0.0% |
BMY leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). KYMR leads in 1 (Total Returns). 1 tied.
AAPG vs ARVN vs KYMR vs BMY: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is AAPG or ARVN or KYMR or BMY a better buy right now?
For growth investors, ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG) is the stronger pick with 341.
8% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). Bristol-Myers Squibb Company (BMY) offers the better valuation at 16. 3x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — AAPG or ARVN or KYMR or BMY?
Over the past 5 years, Kymera Therapeutics, Inc.
(KYMR) delivered a total return of +92. 1%, compared to -84. 0% for Arvinas, Inc. (ARVN). Over 10 years, the gap is even starker: KYMR returned +154. 4% versus ARVN's -36. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — AAPG or ARVN or KYMR or BMY?
By beta (market sensitivity over 5 years), Bristol-Myers Squibb Company (BMY) is the lower-risk stock at 0.
50β versus Kymera Therapeutics, Inc. 's 1. 15β — meaning KYMR is approximately 128% more volatile than BMY relative to the S&P 500. On balance sheet safety, Arvinas, Inc. (ARVN) carries a lower debt/equity ratio of 2% versus 6% for ASCENTAGE PHARMA GROUP INTERNATIONAL — giving it more financial flexibility in a downturn.
04Which is growing faster — AAPG or ARVN or KYMR or BMY?
By revenue growth (latest reported year), ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG) is pulling ahead at 341.
8% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Bristol-Myers Squibb Company grew EPS 178. 2% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Over a 3-year CAGR, AAPG leads at 227. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — AAPG or ARVN or KYMR or BMY?
Bristol-Myers Squibb Company (BMY) is the more profitable company, earning 14.
6% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 14. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: BMY leads at 26. 3% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is AAPG or ARVN or KYMR or BMY more undervalued right now?
Analyst consensus price targets imply the most upside for AAPG: 112.
0% to $46. 00.
07Which pays a better dividend — AAPG or ARVN or KYMR or BMY?
In this comparison, BMY (4.
4% yield) pays a dividend. AAPG, ARVN, KYMR do not pay a meaningful dividend and should not be held primarily for income.
08Is AAPG or ARVN or KYMR or BMY better for a retirement portfolio?
For long-horizon retirement investors, Bristol-Myers Squibb Company (BMY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
50), 4. 4% yield). Both have compounded well over 10 years (BMY: +6. 7%, ARVN: -36. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between AAPG and ARVN and KYMR and BMY?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: AAPG is a small-cap high-growth stock; ARVN is a small-cap quality compounder stock; KYMR is a small-cap quality compounder stock; BMY is a mid-cap deep-value stock. BMY pays a dividend while AAPG, ARVN, KYMR do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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