Biotechnology
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5 / 10Stock Comparison
AAPG vs KYMR vs ABBV vs ARVN vs BMY
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - General
Biotechnology
Drug Manufacturers - General
AAPG vs KYMR vs ABBV vs ARVN vs BMY — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - General | Biotechnology | Drug Manufacturers - General |
| Market Cap | $6.55B | $6.91B | $358.42B | $652M | $114.85B |
| Revenue (TTM) | $1.29B | $51M | $61.16B | $263M | $48.48B |
| Net Income (TTM) | $-1.52B | $-315M | $4.23B | $-81M | $7.28B |
| Gross Margin | 95.1% | 33.2% | 70.2% | 99.5% | 68.7% |
| Operating Margin | -113.2% | -7.0% | 26.7% | -44.0% | 25.7% |
| Forward P/E | — | — | 14.3x | — | 8.9x |
| Total Debt | $1.67B | $82M | $69.07B | $9M | $47.14B |
| Cash & Equiv. | $1.24B | $357M | $5.23B | $143M | $10.21B |
AAPG vs KYMR vs ABBV vs ARVN vs BMY — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jan 25 | May 26 | Return |
|---|---|---|---|
| ASCENTAGE PHARMA GR… (AAPG) | 100 | 122.7 | +22.7% |
| Kymera Therapeutics… (KYMR) | 100 | 213.8 | +113.8% |
| AbbVie Inc. (ABBV) | 100 | 110.2 | +10.2% |
| Arvinas, Inc. (ARVN) | 100 | 57.9 | -42.1% |
| Bristol-Myers Squib… (BMY) | 100 | 95.4 | -4.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AAPG vs KYMR vs ABBV vs ARVN vs BMY
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AAPG ranks third and is worth considering specifically for growth exposure.
- Rev growth 341.8%, EPS growth 89.8%, 3Y rev CAGR 227.5%
- 341.8% revenue growth vs KYMR's -16.7%
KYMR is the clearest fit if your priority is momentum.
- +190.7% vs AAPG's -10.2%
ABBV is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- 295.5% 10Y total return vs KYMR's 154.4%
- Beta 0.34 vs KYMR's 1.15
- 3.2% yield, 13-year raise streak, vs BMY's 4.4%, (3 stocks pay no dividend)
ARVN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.15, Low D/E 2.0%, current ratio 4.92x
BMY carries the broadest edge in this set and is the clearest fit for defensive.
- Beta 0.50, yield 4.4%, current ratio 1.26x
- Better valuation composite
- 15.0% margin vs KYMR's -6.1%
- 7.9% ROA vs AAPG's -49.9%, ROIC 16.9% vs -36.9%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 341.8% revenue growth vs KYMR's -16.7% | |
| Value | Better valuation composite | |
| Quality / Margins | 15.0% margin vs KYMR's -6.1% | |
| Stability / Safety | Beta 0.34 vs KYMR's 1.15 | |
| Dividends | 3.2% yield, 13-year raise streak, vs BMY's 4.4%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +190.7% vs AAPG's -10.2% | |
| Efficiency (ROA) | 7.9% ROA vs AAPG's -49.9%, ROIC 16.9% vs -36.9% |
AAPG vs KYMR vs ABBV vs ARVN vs BMY — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
AAPG vs KYMR vs ABBV vs ARVN vs BMY — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ABBV leads in 1 of 6 categories
BMY leads 1 • KYMR leads 1 • AAPG leads 0 • ARVN leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ABBV leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ABBV is the larger business by revenue, generating $61.2B annually — 1188.4x KYMR's $51M. BMY is the more profitable business, keeping 15.0% of every revenue dollar as net income compared to KYMR's -6.1%. On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $1.3B | $51M | $61.2B | $263M | $48.5B |
| EBITDAEarnings before interest/tax | -$1.3B | -$352M | $24.5B | -$111M | $15.7B |
| Net IncomeAfter-tax profit | -$1.5B | -$315M | $4.2B | -$81M | $7.3B |
| Free Cash FlowCash after capex | -$505M | -$244M | $18.7B | -$276M | $11.9B |
| Gross MarginGross profit ÷ Revenue | +95.1% | +33.2% | +70.2% | +99.5% | +68.7% |
| Operating MarginEBIT ÷ Revenue | -113.2% | -7.0% | +26.7% | -44.0% | +25.7% |
| Net MarginNet income ÷ Revenue | -117.5% | -6.1% | +6.9% | -30.8% | +15.0% |
| FCF MarginFCF ÷ Revenue | -39.1% | -4.7% | +30.6% | -105.0% | +24.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | -71.6% | +55.5% | +10.0% | -84.0% | +2.6% |
| EPS Growth (YoY)Latest quarter vs prior year | -4.1% | +13.4% | +57.4% | -65.1% | +9.2% |
Valuation Metrics
BMY leads this category, winning 4 of 6 comparable metrics.
Valuation Metrics
At 16.3x trailing earnings, BMY trades at a 81% valuation discount to ABBV's 85.5x P/E. On an enterprise value basis, BMY's 9.2x EV/EBITDA is more attractive than ABBV's 15.0x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $6.6B | $6.9B | $358.4B | $652M | $114.8B |
| Enterprise ValueMkt cap + debt − cash | $6.6B | $6.6B | $422.3B | $517M | $151.8B |
| Trailing P/EPrice ÷ TTM EPS | -110.21x | -22.93x | 85.50x | -7.96x | 16.30x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 14.28x | — | 8.93x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 14.96x | — | 9.17x |
| Price / SalesMarket cap ÷ Revenue | 45.49x | 176.26x | 5.86x | 2.48x | 2.38x |
| Price / BookPrice ÷ Book value/share | 162.71x | 4.52x | — | 1.52x | 6.20x |
| Price / FCFMarket cap ÷ FCF | — | — | 20.12x | — | 8.94x |
Profitability & Efficiency
Evenly matched — ABBV and BMY each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-2 for AAPG. ARVN carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to AAPG's 6.09x. On the Piotroski fundamental quality scale (0–9), BMY scores 8/9 vs ARVN's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -2.2% | -25.0% | +62.1% | -14.3% | +39.0% |
| ROA (TTM)Return on assets | -49.9% | -22.3% | +3.1% | -9.3% | +7.9% |
| ROICReturn on invested capital | -36.9% | -24.9% | +23.9% | -22.4% | +16.9% |
| ROCEReturn on capital employed | -24.5% | -27.2% | +21.5% | -16.0% | +18.7% |
| Piotroski ScoreFundamental quality 0–9 | 5 | 4 | 6 | 4 | 8 |
| Debt / EquityFinancial leverage | 6.09x | 0.05x | — | 0.02x | 2.55x |
| Net DebtTotal debt minus cash | $432M | -$275M | $63.8B | -$134M | $36.9B |
| Cash & Equiv.Liquid assets | $1.2B | $357M | $5.2B | $143M | $10.2B |
| Total DebtShort + long-term debt | $1.7B | $82M | $69.1B | $9M | $47.1B |
| Interest CoverageEBIT ÷ Interest expense | -30.31x | -2119.53x | 3.28x | — | 10.33x |
Total Returns (Dividends Reinvested)
KYMR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ABBV five years ago would be worth $20,131 today (with dividends reinvested), compared to $1,601 for ARVN. Over the past 12 months, KYMR leads with a +190.7% total return vs AAPG's -10.2%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs ARVN's -25.5% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -17.7% | +16.3% | -10.1% | -11.2% | +7.6% |
| 1-Year ReturnPast 12 months | -10.2% | +190.7% | +11.3% | +52.8% | +23.4% |
| 3-Year ReturnCumulative with dividends | +24.9% | +205.1% | +50.4% | -58.7% | -7.1% |
| 5-Year ReturnCumulative with dividends | +24.9% | +92.1% | +101.3% | -84.0% | +5.2% |
| 10-Year ReturnCumulative with dividends | +24.9% | +154.4% | +295.5% | -36.5% | +6.7% |
| CAGR (3Y)Annualised 3-year return | +7.7% | +45.0% | +14.6% | -25.5% | -2.4% |
Risk & Volatility
Evenly matched — ABBV and BMY each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than KYMR's 1.15 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BMY currently trades 89.4% from its 52-week high vs AAPG's 44.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.85x | 1.15x | 0.34x | 1.15x | 0.50x |
| 52-Week HighHighest price in past year | $48.45 | $103.00 | $244.81 | $14.51 | $62.89 |
| 52-Week LowLowest price in past year | $20.06 | $28.06 | $176.57 | $5.90 | $42.52 |
| % of 52W HighCurrent price vs 52-week peak | +44.8% | +82.2% | +82.8% | +70.2% | +89.4% |
| RSI (14)Momentum oscillator 0–100 | 37.5 | 54.1 | 46.8 | 42.6 | 41.4 |
| Avg Volume (50D)Average daily shares traded | 3K | 602K | 5.8M | 808K | 10.3M |
Analyst Outlook
Evenly matched — ABBV and BMY each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: AAPG as "Buy", KYMR as "Buy", ABBV as "Buy", ARVN as "Buy", BMY as "Hold". Consensus price targets imply 112.0% upside for AAPG (target: $46) vs 10.2% for BMY (target: $62). For income investors, BMY offers the higher dividend yield at 4.39% vs ABBV's 3.24%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | $46.00 | $117.06 | $256.64 | $13.00 | $62.00 |
| # AnalystsCovering analysts | 1 | 26 | 41 | 26 | 41 |
| Dividend YieldAnnual dividend ÷ price | — | — | +3.2% | — | +4.4% |
| Dividend StreakConsecutive years of raises | — | — | 13 | — | 6 |
| Dividend / ShareAnnual DPS | — | — | $6.57 | — | $2.47 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.3% | +14.1% | 0.0% |
ABBV leads in 1 of 6 categories (Income & Cash Flow). BMY leads in 1 (Valuation Metrics). 3 tied.
AAPG vs KYMR vs ABBV vs ARVN vs BMY: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is AAPG or KYMR or ABBV or ARVN or BMY a better buy right now?
For growth investors, ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG) is the stronger pick with 341.
8% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). Bristol-Myers Squibb Company (BMY) offers the better valuation at 16. 3x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — AAPG or KYMR or ABBV or ARVN or BMY?
On trailing P/E, Bristol-Myers Squibb Company (BMY) is the cheapest at 16.
3x versus AbbVie Inc. at 85. 5x. On forward P/E, Bristol-Myers Squibb Company is actually cheaper at 8. 9x.
03Which is the better long-term investment — AAPG or KYMR or ABBV or ARVN or BMY?
Over the past 5 years, AbbVie Inc.
(ABBV) delivered a total return of +101. 3%, compared to -84. 0% for Arvinas, Inc. (ARVN). Over 10 years, the gap is even starker: ABBV returned +295. 5% versus ARVN's -36. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — AAPG or KYMR or ABBV or ARVN or BMY?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 34β versus Kymera Therapeutics, Inc. 's 1. 15β — meaning KYMR is approximately 240% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Arvinas, Inc. (ARVN) carries a lower debt/equity ratio of 2% versus 6% for ASCENTAGE PHARMA GROUP INTERNATIONAL — giving it more financial flexibility in a downturn.
05Which is growing faster — AAPG or KYMR or ABBV or ARVN or BMY?
By revenue growth (latest reported year), ASCENTAGE PHARMA GROUP INTERNATIONAL (AAPG) is pulling ahead at 341.
8% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Bristol-Myers Squibb Company grew EPS 178. 2% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Over a 3-year CAGR, AAPG leads at 227. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — AAPG or KYMR or ABBV or ARVN or BMY?
Bristol-Myers Squibb Company (BMY) is the more profitable company, earning 14.
6% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 14. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ABBV leads at 32. 8% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is AAPG or KYMR or ABBV or ARVN or BMY more undervalued right now?
On forward earnings alone, Bristol-Myers Squibb Company (BMY) trades at 8.
9x forward P/E versus 14. 3x for AbbVie Inc. — 5. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for AAPG: 112. 0% to $46. 00.
08Which pays a better dividend — AAPG or KYMR or ABBV or ARVN or BMY?
In this comparison, BMY (4.
4% yield), ABBV (3. 2% yield) pay a dividend. AAPG, KYMR, ARVN do not pay a meaningful dividend and should not be held primarily for income.
09Is AAPG or KYMR or ABBV or ARVN or BMY better for a retirement portfolio?
For long-horizon retirement investors, AbbVie Inc.
(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 34), 3. 2% yield, +295. 5% 10Y return). Both have compounded well over 10 years (ABBV: +295. 5%, ARVN: -36. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between AAPG and KYMR and ABBV and ARVN and BMY?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: AAPG is a small-cap high-growth stock; KYMR is a small-cap quality compounder stock; ABBV is a large-cap income-oriented stock; ARVN is a small-cap quality compounder stock; BMY is a mid-cap deep-value stock. ABBV, BMY pay a dividend while AAPG, KYMR, ARVN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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