Biotechnology
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5 / 10Stock Comparison
ABCL vs DBVT vs HALO vs REGN vs MRK
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Drug Manufacturers - General
ABCL vs DBVT vs HALO vs REGN vs MRK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General |
| Market Cap | $1.45B | $1712.35T | $7.68B | $73.68B | $277.34B |
| Revenue (TTM) | $75M | $0.00 | $1.40B | $14.92B | $64.93B |
| Net Income (TTM) | $-146M | $-168M | $317M | $4.42B | $18.25B |
| Gross Margin | -48.2% | — | 81.9% | 84.5% | 74.2% |
| Operating Margin | -402.1% | — | 58.4% | 24.3% | 41.1% |
| Forward P/E | — | — | 8.1x | 15.3x | 21.9x |
| Total Debt | $137M | $22M | $0.00 | $2.71B | $50.53B |
| Cash & Equiv. | $129M | $194M | $134M | $3.12B | $14.56B |
ABCL vs DBVT vs HALO vs REGN vs MRK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 20 | May 26 | Return |
|---|---|---|---|
| AbCellera Biologics… (ABCL) | 100 | 12.0 | -88.0% |
| DBV Technologies S.… (DBVT) | 100 | 76.3 | -23.7% |
| Halozyme Therapeuti… (HALO) | 100 | 152.6 | +52.6% |
| Regeneron Pharmaceu… (REGN) | 100 | 146.8 | +46.8% |
| Merck & Co., Inc. (MRK) | 100 | 144.0 | +44.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ABCL vs DBVT vs HALO vs REGN vs MRK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ABCL is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 160.6%, EPS growth 10.9%, 3Y rev CAGR -46.3%
- 160.6% revenue growth vs DBVT's -100.0%
- +139.8% vs HALO's -7.1%
Among these 5 stocks, DBVT doesn't own a clear edge in any measured category.
HALO ranks third and is worth considering specifically for valuation efficiency.
- PEG 0.35 vs REGN's 2.43
- Lower P/E (8.1x vs 21.9x), PEG 0.35 vs 1.03
REGN is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
- 29.6% margin vs ABCL's -194.9%
MRK carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- Dividend streak 14 yrs, beta 0.48, yield 2.9%
- 166.5% 10Y total return vs HALO's 5.7%
- Beta 0.48, yield 2.9%, current ratio 1.54x
- Beta 0.48 vs ABCL's 2.31
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 160.6% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (8.1x vs 21.9x), PEG 0.35 vs 1.03 | |
| Quality / Margins | 29.6% margin vs ABCL's -194.9% | |
| Stability / Safety | Beta 0.48 vs ABCL's 2.31 | |
| Dividends | 2.9% yield, 14-year raise streak, vs REGN's 0.5%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +139.8% vs HALO's -7.1% | |
| Efficiency (ROA) | 14.6% ROA vs DBVT's -89.0% |
ABCL vs DBVT vs HALO vs REGN vs MRK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ABCL vs DBVT vs HALO vs REGN vs MRK — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 3 of 6 categories
MRK leads 2 • ABCL leads 0 • DBVT leads 0 • REGN leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — HALO and REGN each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
MRK and DBVT operate at a comparable scale, with $64.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to ABCL's -194.9%. On growth, ABCL holds the edge at +7.9% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $75M | $0 | $1.4B | $14.9B | $64.9B |
| EBITDAEarnings before interest/tax | -$280M | -$112M | $945M | $4.2B | $32.4B |
| Net IncomeAfter-tax profit | -$146M | -$168M | $317M | $4.4B | $18.3B |
| Free Cash FlowCash after capex | -$174M | -$151M | $645M | $4.2B | $12.4B |
| Gross MarginGross profit ÷ Revenue | -48.2% | — | +81.9% | +84.5% | +74.2% |
| Operating MarginEBIT ÷ Revenue | -4.0% | — | +58.4% | +24.3% | +41.1% |
| Net MarginNet income ÷ Revenue | -194.9% | — | +22.7% | +29.6% | +28.1% |
| FCF MarginFCF ÷ Revenue | -2.3% | — | +46.2% | +27.9% | +19.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +7.9% | — | +51.6% | +19.0% | +4.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +75.0% | +91.5% | -2.1% | -7.2% | -19.6% |
Valuation Metrics
HALO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 15.4x trailing earnings, MRK trades at a 39% valuation discount to HALO's 25.5x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.73x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.4B | $1712.35T | $7.7B | $73.7B | $277.3B |
| Enterprise ValueMkt cap + debt − cash | $1.5B | $1712.35T | $7.5B | $73.3B | $313.3B |
| Trailing P/EPrice ÷ TTM EPS | -9.84x | -0.76x | 25.46x | 17.09x | 15.42x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 8.09x | 15.35x | 21.93x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.11x | 2.70x | 0.73x |
| EV / EBITDAEnterprise value multiple | — | — | 8.34x | 17.78x | 10.68x |
| Price / SalesMarket cap ÷ Revenue | 19.29x | — | 5.50x | 5.14x | 4.27x |
| Price / BookPrice ÷ Book value/share | 1.49x | 0.66x | 165.47x | 2.46x | 5.35x |
| Price / FCFMarket cap ÷ FCF | — | — | 11.91x | 18.06x | 22.44x |
Profitability & Efficiency
HALO leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-130 for DBVT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs ABCL's 3/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -15.1% | -130.2% | +6.5% | +14.3% | +36.1% |
| ROA (TTM)Return on assets | -23.3% | -89.0% | +12.5% | +11.1% | +14.6% |
| ROICReturn on invested capital | -16.8% | — | +73.4% | +8.9% | +22.0% |
| ROCEReturn on capital employed | -23.5% | -145.7% | +38.2% | +10.2% | +23.8% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 5 | 5 | 4 |
| Debt / EquityFinancial leverage | 0.14x | 0.13x | — | 0.09x | 0.96x |
| Net DebtTotal debt minus cash | $9M | -$172M | -$134M | -$412M | $36.0B |
| Cash & Equiv.Liquid assets | $129M | $194M | $134M | $3.1B | $14.6B |
| Total DebtShort + long-term debt | $137M | $22M | $0 | $2.7B | $50.5B |
| Interest CoverageEBIT ÷ Interest expense | -9.52x | -189.82x | 46.08x | 108.44x | 19.68x |
Total Returns (Dividends Reinvested)
HALO leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MRK five years ago would be worth $17,024 today (with dividends reinvested), compared to $1,657 for ABCL. Over the past 12 months, ABCL leads with a +139.8% total return vs HALO's -7.1%. The 3-year compound annual growth rate (CAGR) favors HALO at 29.1% vs ABCL's -5.5% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +40.5% | +4.9% | -7.3% | -8.5% | +6.3% |
| 1-Year ReturnPast 12 months | +139.8% | +110.4% | -7.1% | +27.1% | +46.1% |
| 3-Year ReturnCumulative with dividends | -15.6% | +19.7% | +115.3% | -5.1% | +2.9% |
| 5-Year ReturnCumulative with dividends | -83.4% | -69.1% | +37.0% | +43.6% | +70.2% |
| 10-Year ReturnCumulative with dividends | -91.8% | -87.0% | +570.7% | +90.0% | +166.5% |
| CAGR (3Y)Annualised 3-year return | -5.5% | +6.2% | +29.1% | -1.7% | +0.9% |
Risk & Volatility
MRK leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
MRK is the less volatile stock with a 0.48 beta — it tends to amplify market swings less than ABCL's 2.31 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs ABCL's 73.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.31x | 1.26x | 0.56x | 0.81x | 0.48x |
| 52-Week HighHighest price in past year | $6.52 | $26.18 | $82.22 | $821.11 | $125.14 |
| 52-Week LowLowest price in past year | $1.94 | $7.53 | $47.50 | $476.49 | $73.31 |
| % of 52W HighCurrent price vs 52-week peak | +73.9% | +76.3% | +79.3% | +86.4% | +89.7% |
| RSI (14)Momentum oscillator 0–100 | 77.5 | 48.1 | 52.4 | 44.9 | 46.7 |
| Avg Volume (50D)Average daily shares traded | 4.5M | 252K | 1.4M | 631K | 7.3M |
Analyst Outlook
MRK leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ABCL as "Buy", DBVT as "Buy", HALO as "Buy", REGN as "Buy", MRK as "Buy". Consensus price targets imply 318.5% upside for ABCL (target: $20) vs 15.2% for MRK (target: $129). For income investors, MRK offers the higher dividend yield at 2.90% vs REGN's 0.48%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $20.17 | $46.33 | $78.33 | $865.68 | $129.31 |
| # AnalystsCovering analysts | 11 | 15 | 27 | 48 | 37 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +0.5% | +2.9% |
| Dividend StreakConsecutive years of raises | — | 0 | — | 1 | 14 |
| Dividend / ShareAnnual DPS | — | — | — | $3.41 | $3.26 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +4.5% | +5.4% | +1.8% |
HALO leads in 3 of 6 categories (Valuation Metrics, Profitability & Efficiency). MRK leads in 2 (Risk & Volatility, Analyst Outlook). 1 tied.
ABCL vs DBVT vs HALO vs REGN vs MRK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ABCL or DBVT or HALO or REGN or MRK a better buy right now?
For growth investors, AbCellera Biologics Inc.
(ABCL) is the stronger pick with 160. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 4x trailing P/E (21. 9x forward), making it the more compelling value choice. Analysts rate AbCellera Biologics Inc. (ABCL) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ABCL or DBVT or HALO or REGN or MRK?
On trailing P/E, Merck & Co.
, Inc. (MRK) is the cheapest at 15. 4x versus Halozyme Therapeutics, Inc. at 25. 5x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 1x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — ABCL or DBVT or HALO or REGN or MRK?
Over the past 5 years, Merck & Co.
, Inc. (MRK) delivered a total return of +70. 2%, compared to -83. 4% for AbCellera Biologics Inc. (ABCL). Over 10 years, the gap is even starker: HALO returned +570. 7% versus ABCL's -91. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ABCL or DBVT or HALO or REGN or MRK?
By beta (market sensitivity over 5 years), Merck & Co.
, Inc. (MRK) is the lower-risk stock at 0. 48β versus AbCellera Biologics Inc. 's 2. 31β — meaning ABCL is approximately 386% more volatile than MRK relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — ABCL or DBVT or HALO or REGN or MRK?
By revenue growth (latest reported year), AbCellera Biologics Inc.
(ABCL) is pulling ahead at 160. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: AbCellera Biologics Inc. grew EPS 10. 9% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ABCL or DBVT or HALO or REGN or MRK?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus -194. 9% for AbCellera Biologics Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -289. 0% for ABCL. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ABCL or DBVT or HALO or REGN or MRK more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 1x forward P/E versus 21. 9x for Merck & Co. , Inc. — 13. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ABCL: 318. 5% to $20. 17.
08Which pays a better dividend — ABCL or DBVT or HALO or REGN or MRK?
In this comparison, MRK (2.
9% yield), REGN (0. 5% yield) pay a dividend. ABCL, DBVT, HALO do not pay a meaningful dividend and should not be held primarily for income.
09Is ABCL or DBVT or HALO or REGN or MRK better for a retirement portfolio?
For long-horizon retirement investors, Merck & Co.
, Inc. (MRK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 48), 2. 9% yield, +166. 5% 10Y return). AbCellera Biologics Inc. (ABCL) carries a higher beta of 2. 31 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (MRK: +166. 5%, ABCL: -91. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ABCL and DBVT and HALO and REGN and MRK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ABCL is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; HALO is a small-cap high-growth stock; REGN is a mid-cap deep-value stock; MRK is a large-cap deep-value stock. MRK pays a dividend while ABCL, DBVT, HALO, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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