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ABCL vs DBVT vs HALO vs REGN vs MRK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ABCL
AbCellera Biologics Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$1.45B
5Y Perf.-88.0%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-23.7%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.68B
5Y Perf.+52.6%
REGN
Regeneron Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$73.68B
5Y Perf.+46.8%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+44.0%

ABCL vs DBVT vs HALO vs REGN vs MRK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ABCL logoABCL
DBVT logoDBVT
HALO logoHALO
REGN logoREGN
MRK logoMRK
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - General
Market Cap$1.45B$1712.35T$7.68B$73.68B$277.34B
Revenue (TTM)$75M$0.00$1.40B$14.92B$64.93B
Net Income (TTM)$-146M$-168M$317M$4.42B$18.25B
Gross Margin-48.2%81.9%84.5%74.2%
Operating Margin-402.1%58.4%24.3%41.1%
Forward P/E8.1x15.3x21.9x
Total Debt$137M$22M$0.00$2.71B$50.53B
Cash & Equiv.$129M$194M$134M$3.12B$14.56B

ABCL vs DBVT vs HALO vs REGN vs MRKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ABCL
DBVT
HALO
REGN
MRK
StockDec 20May 26Return
AbCellera Biologics… (ABCL)10012.0-88.0%
DBV Technologies S.… (DBVT)10076.3-23.7%
Halozyme Therapeuti… (HALO)100152.6+52.6%
Regeneron Pharmaceu… (REGN)100146.8+46.8%
Merck & Co., Inc. (MRK)100144.0+44.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: ABCL vs DBVT vs HALO vs REGN vs MRK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: MRK leads in 3 of 7 categories (5-stock set), making it the strongest pick for capital preservation and lower volatility and dividend income and shareholder returns. AbCellera Biologics Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. HALO and REGN also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
ABCL
AbCellera Biologics Inc.
The Growth Play

ABCL is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 160.6%, EPS growth 10.9%, 3Y rev CAGR -46.3%
  • 160.6% revenue growth vs DBVT's -100.0%
  • +139.8% vs HALO's -7.1%
Best for: growth exposure
DBVT
DBV Technologies S.A.
The Healthcare Pick

Among these 5 stocks, DBVT doesn't own a clear edge in any measured category.

Best for: healthcare exposure
HALO
Halozyme Therapeutics, Inc.
The Value Pick

HALO ranks third and is worth considering specifically for valuation efficiency.

  • PEG 0.35 vs REGN's 2.43
  • Lower P/E (8.1x vs 21.9x), PEG 0.35 vs 1.03
Best for: valuation efficiency
REGN
Regeneron Pharmaceuticals, Inc.
The Defensive Pick

REGN is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
  • 29.6% margin vs ABCL's -194.9%
Best for: sleep-well-at-night
MRK
Merck & Co., Inc.
The Income Pick

MRK carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.

  • Dividend streak 14 yrs, beta 0.48, yield 2.9%
  • 166.5% 10Y total return vs HALO's 5.7%
  • Beta 0.48, yield 2.9%, current ratio 1.54x
  • Beta 0.48 vs ABCL's 2.31
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthABCL logoABCL160.6% revenue growth vs DBVT's -100.0%
ValueHALO logoHALOLower P/E (8.1x vs 21.9x), PEG 0.35 vs 1.03
Quality / MarginsREGN logoREGN29.6% margin vs ABCL's -194.9%
Stability / SafetyMRK logoMRKBeta 0.48 vs ABCL's 2.31
DividendsMRK logoMRK2.9% yield, 14-year raise streak, vs REGN's 0.5%, (3 stocks pay no dividend)
Momentum (1Y)ABCL logoABCL+139.8% vs HALO's -7.1%
Efficiency (ROA)MRK logoMRK14.6% ROA vs DBVT's -89.0%

ABCL vs DBVT vs HALO vs REGN vs MRK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ABCLAbCellera Biologics Inc.
FY 2025
License
62.5%$47M
Research Fees
36.2%$27M
Milestone Payments
1.3%$1M
DBVTDBV Technologies S.A.

Segment breakdown not available.

HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M
REGNRegeneron Pharmaceuticals, Inc.
FY 2025
Collaboration Revenue
51.1%$7.3B
Product
44.0%$6.3B
Product and Service, Other
4.9%$703M
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M

ABCL vs DBVT vs HALO vs REGN vs MRK — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHALOLAGGINGREGN

Income & Cash Flow (Last 12 Months)

Evenly matched — HALO and REGN each lead in 2 of 6 comparable metrics.

MRK and DBVT operate at a comparable scale, with $64.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to ABCL's -194.9%. On growth, ABCL holds the edge at +7.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricABCL logoABCLAbCellera Biologi…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…REGN logoREGNRegeneron Pharmac…MRK logoMRKMerck & Co., Inc.
RevenueTrailing 12 months$75M$0$1.4B$14.9B$64.9B
EBITDAEarnings before interest/tax-$280M-$112M$945M$4.2B$32.4B
Net IncomeAfter-tax profit-$146M-$168M$317M$4.4B$18.3B
Free Cash FlowCash after capex-$174M-$151M$645M$4.2B$12.4B
Gross MarginGross profit ÷ Revenue-48.2%+81.9%+84.5%+74.2%
Operating MarginEBIT ÷ Revenue-4.0%+58.4%+24.3%+41.1%
Net MarginNet income ÷ Revenue-194.9%+22.7%+29.6%+28.1%
FCF MarginFCF ÷ Revenue-2.3%+46.2%+27.9%+19.0%
Rev. Growth (YoY)Latest quarter vs prior year+7.9%+51.6%+19.0%+4.5%
EPS Growth (YoY)Latest quarter vs prior year+75.0%+91.5%-2.1%-7.2%-19.6%
Evenly matched — HALO and REGN each lead in 2 of 6 comparable metrics.

Valuation Metrics

HALO leads this category, winning 3 of 7 comparable metrics.

At 15.4x trailing earnings, MRK trades at a 39% valuation discount to HALO's 25.5x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.73x vs REGN's 2.70x — a lower PEG means you pay less per unit of expected earnings growth.

MetricABCL logoABCLAbCellera Biologi…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…REGN logoREGNRegeneron Pharmac…MRK logoMRKMerck & Co., Inc.
Market CapShares × price$1.4B$1712.35T$7.7B$73.7B$277.3B
Enterprise ValueMkt cap + debt − cash$1.5B$1712.35T$7.5B$73.3B$313.3B
Trailing P/EPrice ÷ TTM EPS-9.84x-0.76x25.46x17.09x15.42x
Forward P/EPrice ÷ next-FY EPS est.8.09x15.35x21.93x
PEG RatioP/E ÷ EPS growth rate1.11x2.70x0.73x
EV / EBITDAEnterprise value multiple8.34x17.78x10.68x
Price / SalesMarket cap ÷ Revenue19.29x5.50x5.14x4.27x
Price / BookPrice ÷ Book value/share1.49x0.66x165.47x2.46x5.35x
Price / FCFMarket cap ÷ FCF11.91x18.06x22.44x
HALO leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

HALO leads this category, winning 5 of 9 comparable metrics.

HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-130 for DBVT. REGN carries lower financial leverage with a 0.09x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs ABCL's 3/9, reflecting solid financial health.

MetricABCL logoABCLAbCellera Biologi…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…REGN logoREGNRegeneron Pharmac…MRK logoMRKMerck & Co., Inc.
ROE (TTM)Return on equity-15.1%-130.2%+6.5%+14.3%+36.1%
ROA (TTM)Return on assets-23.3%-89.0%+12.5%+11.1%+14.6%
ROICReturn on invested capital-16.8%+73.4%+8.9%+22.0%
ROCEReturn on capital employed-23.5%-145.7%+38.2%+10.2%+23.8%
Piotroski ScoreFundamental quality 0–934554
Debt / EquityFinancial leverage0.14x0.13x0.09x0.96x
Net DebtTotal debt minus cash$9M-$172M-$134M-$412M$36.0B
Cash & Equiv.Liquid assets$129M$194M$134M$3.1B$14.6B
Total DebtShort + long-term debt$137M$22M$0$2.7B$50.5B
Interest CoverageEBIT ÷ Interest expense-9.52x-189.82x46.08x108.44x19.68x
HALO leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

HALO leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in MRK five years ago would be worth $17,024 today (with dividends reinvested), compared to $1,657 for ABCL. Over the past 12 months, ABCL leads with a +139.8% total return vs HALO's -7.1%. The 3-year compound annual growth rate (CAGR) favors HALO at 29.1% vs ABCL's -5.5% — a key indicator of consistent wealth creation.

MetricABCL logoABCLAbCellera Biologi…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…REGN logoREGNRegeneron Pharmac…MRK logoMRKMerck & Co., Inc.
YTD ReturnYear-to-date+40.5%+4.9%-7.3%-8.5%+6.3%
1-Year ReturnPast 12 months+139.8%+110.4%-7.1%+27.1%+46.1%
3-Year ReturnCumulative with dividends-15.6%+19.7%+115.3%-5.1%+2.9%
5-Year ReturnCumulative with dividends-83.4%-69.1%+37.0%+43.6%+70.2%
10-Year ReturnCumulative with dividends-91.8%-87.0%+570.7%+90.0%+166.5%
CAGR (3Y)Annualised 3-year return-5.5%+6.2%+29.1%-1.7%+0.9%
HALO leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

MRK leads this category, winning 2 of 2 comparable metrics.

MRK is the less volatile stock with a 0.48 beta — it tends to amplify market swings less than ABCL's 2.31 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs ABCL's 73.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricABCL logoABCLAbCellera Biologi…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…REGN logoREGNRegeneron Pharmac…MRK logoMRKMerck & Co., Inc.
Beta (5Y)Sensitivity to S&P 5002.31x1.26x0.56x0.81x0.48x
52-Week HighHighest price in past year$6.52$26.18$82.22$821.11$125.14
52-Week LowLowest price in past year$1.94$7.53$47.50$476.49$73.31
% of 52W HighCurrent price vs 52-week peak+73.9%+76.3%+79.3%+86.4%+89.7%
RSI (14)Momentum oscillator 0–10077.548.152.444.946.7
Avg Volume (50D)Average daily shares traded4.5M252K1.4M631K7.3M
MRK leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

MRK leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: ABCL as "Buy", DBVT as "Buy", HALO as "Buy", REGN as "Buy", MRK as "Buy". Consensus price targets imply 318.5% upside for ABCL (target: $20) vs 15.2% for MRK (target: $129). For income investors, MRK offers the higher dividend yield at 2.90% vs REGN's 0.48%.

MetricABCL logoABCLAbCellera Biologi…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…REGN logoREGNRegeneron Pharmac…MRK logoMRKMerck & Co., Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$20.17$46.33$78.33$865.68$129.31
# AnalystsCovering analysts1115274837
Dividend YieldAnnual dividend ÷ price+0.5%+2.9%
Dividend StreakConsecutive years of raises0114
Dividend / ShareAnnual DPS$3.41$3.26
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+4.5%+5.4%+1.8%
MRK leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

HALO leads in 3 of 6 categories (Valuation Metrics, Profitability & Efficiency). MRK leads in 2 (Risk & Volatility, Analyst Outlook). 1 tied.

Best OverallHalozyme Therapeutics, Inc. (HALO)Leads 3 of 6 categories
Loading custom metrics...

ABCL vs DBVT vs HALO vs REGN vs MRK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ABCL or DBVT or HALO or REGN or MRK a better buy right now?

For growth investors, AbCellera Biologics Inc.

(ABCL) is the stronger pick with 160. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 4x trailing P/E (21. 9x forward), making it the more compelling value choice. Analysts rate AbCellera Biologics Inc. (ABCL) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ABCL or DBVT or HALO or REGN or MRK?

On trailing P/E, Merck & Co.

, Inc. (MRK) is the cheapest at 15. 4x versus Halozyme Therapeutics, Inc. at 25. 5x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 1x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — ABCL or DBVT or HALO or REGN or MRK?

Over the past 5 years, Merck & Co.

, Inc. (MRK) delivered a total return of +70. 2%, compared to -83. 4% for AbCellera Biologics Inc. (ABCL). Over 10 years, the gap is even starker: HALO returned +570. 7% versus ABCL's -91. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ABCL or DBVT or HALO or REGN or MRK?

By beta (market sensitivity over 5 years), Merck & Co.

, Inc. (MRK) is the lower-risk stock at 0. 48β versus AbCellera Biologics Inc. 's 2. 31β — meaning ABCL is approximately 386% more volatile than MRK relative to the S&P 500. On balance sheet safety, Regeneron Pharmaceuticals, Inc. (REGN) carries a lower debt/equity ratio of 9% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ABCL or DBVT or HALO or REGN or MRK?

By revenue growth (latest reported year), AbCellera Biologics Inc.

(ABCL) is pulling ahead at 160. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: AbCellera Biologics Inc. grew EPS 10. 9% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ABCL or DBVT or HALO or REGN or MRK?

Regeneron Pharmaceuticals, Inc.

(REGN) is the more profitable company, earning 31. 4% net margin versus -194. 9% for AbCellera Biologics Inc. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -289. 0% for ABCL. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ABCL or DBVT or HALO or REGN or MRK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 43x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 1x forward P/E versus 21. 9x for Merck & Co. , Inc. — 13. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ABCL: 318. 5% to $20. 17.

08

Which pays a better dividend — ABCL or DBVT or HALO or REGN or MRK?

In this comparison, MRK (2.

9% yield), REGN (0. 5% yield) pay a dividend. ABCL, DBVT, HALO do not pay a meaningful dividend and should not be held primarily for income.

09

Is ABCL or DBVT or HALO or REGN or MRK better for a retirement portfolio?

For long-horizon retirement investors, Merck & Co.

, Inc. (MRK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 48), 2. 9% yield, +166. 5% 10Y return). AbCellera Biologics Inc. (ABCL) carries a higher beta of 2. 31 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (MRK: +166. 5%, ABCL: -91. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ABCL and DBVT and HALO and REGN and MRK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ABCL is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; HALO is a small-cap high-growth stock; REGN is a mid-cap deep-value stock; MRK is a large-cap deep-value stock. MRK pays a dividend while ABCL, DBVT, HALO, REGN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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