Biotechnology
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5 / 10Stock Comparison
ALT vs DBVT vs HALO vs NVO vs MRK
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Drug Manufacturers - General
Drug Manufacturers - General
ALT vs DBVT vs HALO vs NVO vs MRK — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $343M | $1690.08T | $7.55B | $204.73B | $275.10B |
| Revenue (TTM) | $41K | $0.00 | $1.40B | $327.80B | $64.93B |
| Net Income (TTM) | $-88M | $-168M | $317M | $121.96B | $18.25B |
| Gross Margin | -364.5% | — | 81.9% | 81.8% | 74.2% |
| Operating Margin | -2304.6% | — | 58.4% | 45.3% | 41.1% |
| Forward P/E | — | — | 8.0x | 2.1x | 21.7x |
| Total Debt | $34M | $22M | $0.00 | $130.96B | $50.53B |
| Cash & Equiv. | $44M | $194M | $134M | $26.46B | $14.56B |
ALT vs DBVT vs HALO vs NVO vs MRK — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Altimmune, Inc. (ALT) | 100 | 33.3 | -66.7% |
| DBV Technologies S.… (DBVT) | 100 | 40.7 | -59.3% |
| Halozyme Therapeuti… (HALO) | 100 | 264.2 | +164.2% |
| Novo Nordisk A/S (NVO) | 100 | 139.7 | +39.7% |
| Merck & Co., Inc. (MRK) | 100 | 144.7 | +44.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ALT vs DBVT vs HALO vs NVO vs MRK
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ALT is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 105.0%, EPS growth 25.4%
- 105.0% revenue growth vs DBVT's -100.0%
DBVT ranks third and is worth considering specifically for sleep-well-at-night.
- Lower volatility, beta 1.26, Low D/E 12.8%, current ratio 3.67x
- +100.5% vs ALT's -46.7%
HALO is the clearest fit if your priority is long-term compounding.
- 5.6% 10Y total return vs MRK's 164.7%
NVO carries the broadest edge in this set and is the clearest fit for valuation efficiency.
- PEG 0.10 vs MRK's 1.02
- Lower P/E (2.1x vs 21.7x), PEG 0.10 vs 1.02
- 37.2% margin vs ALT's -2.1K%
- 4.0% yield, 8-year raise streak, vs MRK's 2.9%, (3 stocks pay no dividend)
MRK is the clearest fit if your priority is income & stability and defensive.
- Dividend streak 14 yrs, beta 0.45, yield 2.9%
- Beta 0.45, yield 2.9%, current ratio 1.54x
- Beta 0.45 vs NVO's 1.52
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 105.0% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (2.1x vs 21.7x), PEG 0.10 vs 1.02 | |
| Quality / Margins | 37.2% margin vs ALT's -2.1K% | |
| Stability / Safety | Beta 0.45 vs NVO's 1.52 | |
| Dividends | 4.0% yield, 8-year raise streak, vs MRK's 2.9%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +100.5% vs ALT's -46.7% | |
| Efficiency (ROA) | 23.3% ROA vs DBVT's -89.0% |
ALT vs DBVT vs HALO vs NVO vs MRK — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ALT vs DBVT vs HALO vs NVO vs MRK — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 2 of 6 categories
NVO leads 1 • MRK leads 1 • ALT leads 0 • DBVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
HALO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVO and DBVT operate at a comparable scale, with $327.8B and $0 in trailing revenue. NVO is the more profitable business, keeping 37.2% of every revenue dollar as net income compared to ALT's -2148.6%.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $41,000 | $0 | $1.4B | $327.8B | $64.9B |
| EBITDAEarnings before interest/tax | -$94M | -$112M | $945M | $170.2B | $32.4B |
| Net IncomeAfter-tax profit | -$88M | -$168M | $317M | $122.0B | $18.3B |
| Free Cash FlowCash after capex | -$68M | -$151M | $645M | $31.0B | $12.4B |
| Gross MarginGross profit ÷ Revenue | -364.5% | — | +81.9% | +81.8% | +74.2% |
| Operating MarginEBIT ÷ Revenue | -2304.6% | — | +58.4% | +45.3% | +41.1% |
| Net MarginNet income ÷ Revenue | -2148.6% | — | +22.7% | +37.2% | +28.1% |
| FCF MarginFCF ÷ Revenue | -1654.7% | — | +46.2% | +9.5% | +19.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +4.2% | — | +51.6% | +24.0% | +4.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +18.2% | +91.5% | -2.1% | +67.1% | -19.6% |
Valuation Metrics
NVO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 12.7x trailing earnings, NVO trades at a 49% valuation discount to HALO's 25.0x P/E. Adjusting for growth (PEG ratio), NVO offers better value at 0.62x vs HALO's 1.09x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $343M | $1690.08T | $7.6B | $204.7B | $275.1B |
| Enterprise ValueMkt cap + debt − cash | $333M | $1690.08T | $7.4B | $221.1B | $311.1B |
| Trailing P/EPrice ÷ TTM EPS | -3.09x | -0.75x | 25.05x | 12.74x | 15.30x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 7.96x | 2.13x | 21.69x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.09x | 0.62x | 0.72x |
| EV / EBITDAEnterprise value multiple | — | — | 8.20x | 9.41x | 10.61x |
| Price / SalesMarket cap ÷ Revenue | 8356.77x | — | 5.41x | 4.22x | 4.24x |
| Price / BookPrice ÷ Book value/share | 1.21x | 0.65x | 162.76x | 6.72x | 5.30x |
| Price / FCFMarket cap ÷ FCF | — | — | 11.72x | 44.96x | 22.26x |
Profitability & Efficiency
HALO leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRK's 0.96x. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs MRK's 4/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -49.4% | -130.2% | +6.5% | +66.4% | +36.1% |
| ROA (TTM)Return on assets | -41.7% | -89.0% | +12.5% | +23.3% | +14.6% |
| ROICReturn on invested capital | -46.7% | — | +73.4% | +36.2% | +22.0% |
| ROCEReturn on capital employed | -48.0% | -145.7% | +38.2% | +44.4% | +23.8% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 5 | 5 | 4 |
| Debt / EquityFinancial leverage | 0.15x | 0.13x | — | 0.67x | 0.96x |
| Net DebtTotal debt minus cash | -$9M | -$172M | -$134M | $104.5B | $36.0B |
| Cash & Equiv.Liquid assets | $44M | $194M | $134M | $26.5B | $14.6B |
| Total DebtShort + long-term debt | $34M | $22M | $0 | $131.0B | $50.5B |
| Interest CoverageEBIT ÷ Interest expense | -54.74x | -189.82x | 46.08x | 18.90x | 19.68x |
Total Returns (Dividends Reinvested)
Evenly matched — HALO and MRK each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MRK five years ago would be worth $16,955 today (with dividends reinvested), compared to $2,362 for ALT. Over the past 12 months, DBVT leads with a +100.5% total return vs ALT's -46.7%. The 3-year compound annual growth rate (CAGR) favors HALO at 28.4% vs NVO's -15.9% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -12.0% | +3.6% | -8.8% | -9.7% | +5.4% |
| 1-Year ReturnPast 12 months | -46.7% | +100.5% | -5.3% | -26.2% | +47.7% |
| 3-Year ReturnCumulative with dividends | -37.2% | +18.1% | +111.8% | -40.4% | +2.1% |
| 5-Year ReturnCumulative with dividends | -76.4% | -68.3% | +39.1% | +35.9% | +69.5% |
| 10-Year ReturnCumulative with dividends | +1213.1% | -87.1% | +559.7% | +100.4% | +164.7% |
| CAGR (3Y)Annualised 3-year return | -14.4% | +5.7% | +28.4% | -15.9% | +0.7% |
Risk & Volatility
MRK leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
MRK is the less volatile stock with a 0.45 beta — it tends to amplify market swings less than NVO's 1.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.0% from its 52-week high vs ALT's 40.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.39x | 1.26x | 0.51x | 1.52x | 0.45x |
| 52-Week HighHighest price in past year | $7.73 | $26.18 | $82.22 | $81.44 | $125.14 |
| 52-Week LowLowest price in past year | $2.56 | $7.53 | $47.50 | $35.12 | $73.31 |
| % of 52W HighCurrent price vs 52-week peak | +40.0% | +75.3% | +78.0% | +56.6% | +89.0% |
| RSI (14)Momentum oscillator 0–100 | 46.4 | 47.4 | 47.7 | 73.4 | 43.7 |
| Avg Volume (50D)Average daily shares traded | 4.1M | 252K | 1.4M | 17.9M | 7.2M |
Analyst Outlook
Evenly matched — NVO and MRK each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ALT as "Buy", DBVT as "Buy", HALO as "Buy", NVO as "Buy", MRK as "Buy". Consensus price targets imply 264.1% upside for ALT (target: $11) vs 2.0% for NVO (target: $47). For income investors, NVO offers the higher dividend yield at 3.97% vs MRK's 2.93%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $11.25 | $46.33 | $75.60 | $47.00 | $129.31 |
| # AnalystsCovering analysts | 15 | 15 | 27 | 39 | 37 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +4.0% | +2.9% |
| Dividend StreakConsecutive years of raises | — | 0 | — | 8 | 14 |
| Dividend / ShareAnnual DPS | — | — | — | $11.64 | $3.26 |
| Buyback YieldShare repurchases ÷ mkt cap | +0.1% | 0.0% | +4.5% | +0.1% | +1.8% |
HALO leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NVO leads in 1 (Valuation Metrics). 2 tied.
ALT vs DBVT vs HALO vs NVO vs MRK: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ALT or DBVT or HALO or NVO or MRK a better buy right now?
For growth investors, Altimmune, Inc.
(ALT) is the stronger pick with 105. 0% revenue growth year-over-year, versus 1. 2% for Merck & Co. , Inc. (MRK). Novo Nordisk A/S (NVO) offers the better valuation at 12. 7x trailing P/E (2. 1x forward), making it the more compelling value choice. Analysts rate Altimmune, Inc. (ALT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ALT or DBVT or HALO or NVO or MRK?
On trailing P/E, Novo Nordisk A/S (NVO) is the cheapest at 12.
7x versus Halozyme Therapeutics, Inc. at 25. 0x. On forward P/E, Novo Nordisk A/S is actually cheaper at 2. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Novo Nordisk A/S wins at 0. 10x versus Merck & Co. , Inc. 's 1. 02x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — ALT or DBVT or HALO or NVO or MRK?
Over the past 5 years, Merck & Co.
, Inc. (MRK) delivered a total return of +69. 5%, compared to -76. 4% for Altimmune, Inc. (ALT). Over 10 years, the gap is even starker: ALT returned +1213% versus DBVT's -87. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ALT or DBVT or HALO or NVO or MRK?
By beta (market sensitivity over 5 years), Merck & Co.
, Inc. (MRK) is the lower-risk stock at 0. 45β versus Novo Nordisk A/S's 1. 52β — meaning NVO is approximately 235% more volatile than MRK relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 96% for Merck & Co. , Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — ALT or DBVT or HALO or NVO or MRK?
By revenue growth (latest reported year), Altimmune, Inc.
(ALT) is pulling ahead at 105. 0% versus 1. 2% for Merck & Co. , Inc. (MRK). On earnings-per-share growth, the picture is similar: Altimmune, Inc. grew EPS 25. 4% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ALT or DBVT or HALO or NVO or MRK?
Novo Nordisk A/S (NVO) is the more profitable company, earning 33.
1% net margin versus -2148. 6% for Altimmune, Inc. — meaning it keeps 33. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -2304. 6% for ALT. At the gross margin level — before operating expenses — NVO leads at 81. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ALT or DBVT or HALO or NVO or MRK more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Novo Nordisk A/S (NVO) is the more undervalued stock at a PEG of 0. 10x versus Merck & Co. , Inc. 's 1. 02x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Novo Nordisk A/S (NVO) trades at 2. 1x forward P/E versus 21. 7x for Merck & Co. , Inc. — 19. 6x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ALT: 264. 1% to $11. 25.
08Which pays a better dividend — ALT or DBVT or HALO or NVO or MRK?
In this comparison, NVO (4.
0% yield), MRK (2. 9% yield) pay a dividend. ALT, DBVT, HALO do not pay a meaningful dividend and should not be held primarily for income.
09Is ALT or DBVT or HALO or NVO or MRK better for a retirement portfolio?
For long-horizon retirement investors, Merck & Co.
, Inc. (MRK) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 45), 2. 9% yield, +164. 7% 10Y return). Both have compounded well over 10 years (MRK: +164. 7%, DBVT: -87. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ALT and DBVT and HALO and NVO and MRK?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ALT is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; HALO is a small-cap high-growth stock; NVO is a large-cap deep-value stock; MRK is a large-cap deep-value stock. NVO, MRK pay a dividend while ALT, DBVT, HALO do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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