Biotechnology
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Side-by-side financial analysisStock Comparison
ANL vs ZLAB vs ZYME vs CAN vs IMVT
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Computer Hardware
Biotechnology
ANL vs ZLAB vs ZYME vs CAN vs IMVT — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Computer Hardware | Biotechnology |
| Market Cap | $322M | $1.89B | $1.68B | $203M | $6.90B |
| Revenue (TTM) | $6M | $453M | $81M | $530M | $0.00 |
| Net Income (TTM) | $-54M | $-178M | $-103M | $-210M | $-506M |
| Gross Margin | 100.0% | 57.9% | 94.4% | 7.8% | — |
| Operating Margin | -10.0% | -53.5% | -140.4% | -19.3% | — |
| Forward P/E | — | — | 15.5x | — | — |
| Total Debt | $27M | $224M | $18M | $55M | $72K |
| Cash & Equiv. | $61M | $680M | $41M | $81M | $902M |
ANL vs ZLAB vs ZYME vs CAN vs IMVT — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 23 | Jun 26 | Return |
|---|---|---|---|
| Adlai Nortye Ltd. (ANL) | 100 | 68.8 | -31.2% |
| Zai Lab Limited (ZLAB) | 100 | 70.2 | -29.8% |
| Zymeworks Inc. (ZYME) | 100 | 360.9 | +260.9% |
| Canaan Inc. (CAN) | 100 | 17.6 | -82.4% |
| Immunovant, Inc. (IMVT) | 100 | 87.6 | -12.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ANL vs ZLAB vs ZYME vs CAN vs IMVT
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ANL is the #2 pick in this set and the best alternative if momentum is your priority.
- +5.5% vs ZLAB's -60.3%
Among these 5 stocks, ZLAB doesn't own a clear edge in any measured category.
ZYME carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- beta 0.87
- Lower volatility, beta 0.87, Low D/E 6.8%, current ratio 5.52x
- Beta 0.87, current ratio 5.52x
- Beta 0.87 vs CAN's 4.24, lower leverage
CAN ranks third and is worth considering specifically for growth exposure.
- Rev growth 96.7%, EPS growth 51.1%, 3Y rev CAGR -6.7%
- 96.7% revenue growth vs ANL's -100.0%
IMVT is the clearest fit if your priority is long-term compounding.
- 237.9% 10Y total return vs ZYME's 76.0%
- 2.6% margin vs ANL's -8.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 96.7% revenue growth vs ANL's -100.0% | |
| Quality / Margins | 2.6% margin vs ANL's -8.3% | |
| Stability / Safety | Beta 0.87 vs CAN's 4.24, lower leverage | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +5.5% vs ZLAB's -60.3% | |
| Efficiency (ROA) | -0.1% ROA vs IMVT's -62.2% |
ANL vs ZLAB vs ZYME vs CAN vs IMVT — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ANL vs ZLAB vs ZYME vs CAN vs IMVT — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
CAN leads in 1 of 6 categories
IMVT leads 1 • ANL leads 0 • ZLAB leads 0 • ZYME leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ANL and ZLAB and CAN each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
CAN and IMVT operate at a comparable scale, with $530M and $0 in trailing revenue. Profitability is closely matched — net margins range from -39.3% (ZLAB) to -8.3% (ANL). On growth, CAN holds the edge at +121.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $6M | $453M | $81M | $530M | $0 |
| EBITDAEarnings before interest/tax | -$64M | -$227M | -$118M | -$140M | -$532M |
| Net IncomeAfter-tax profit | -$54M | -$178M | -$103M | -$210M | -$506M |
| Free Cash FlowCash after capex | -$67M | -$129M | -$45.7B | $0 | -$407M |
| Gross MarginGross profit ÷ Revenue | +100.0% | +57.9% | +94.4% | +7.8% | — |
| Operating MarginEBIT ÷ Revenue | -10.0% | -53.5% | -140.4% | -19.3% | — |
| Net MarginNet income ÷ Revenue | -8.3% | -39.3% | -126.3% | -39.7% | — |
| FCF MarginFCF ÷ Revenue | -10.3% | -28.5% | -563.0% | — | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -6.5% | -91.1% | +121.1% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +78.7% | -11.1% | -96.7% | +59.4% | -14.1% |
Valuation Metrics
CAN leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $322M | $1.9B | $1.7B | $203M | $6.9B |
| Enterprise ValueMkt cap + debt − cash | $289M | $1.4B | $1.7B | $177M | $6.0B |
| Trailing P/EPrice ÷ TTM EPS | -2.11x | -10.67x | -21.19x | -0.71x | -12.14x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 15.46x | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 4.11x | 15.89x | 0.38x | — |
| Price / BookPrice ÷ Book value/share | 4.31x | 2.61x | 6.42x | 0.34x | 7.19x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
IMVT leads this category, winning 3 of 9 comparable metrics.
Profitability & Efficiency
ZYME delivers a -0.2% return on equity — every $100 of shareholder capital generates $-0 in annual profit, vs $-101 for ANL. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ANL's 1.07x. On the Piotroski fundamental quality scale (0–9), CAN scores 6/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -101.3% | -24.3% | -0.2% | -60.7% | -68.2% |
| ROA (TTM)Return on assets | -50.2% | -15.5% | -0.1% | -34.6% | -62.2% |
| ROICReturn on invested capital | -7.3% | -41.7% | -25.9% | -24.9% | — |
| ROCEReturn on capital employed | -103.8% | -27.2% | -27.3% | -29.7% | -68.3% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 3 | 5 | 6 | 2 |
| Debt / EquityFinancial leverage | 1.07x | 0.31x | 0.07x | 0.13x | 0.00x |
| Net DebtTotal debt minus cash | -$34M | -$455M | -$23M | -$26M | -$902M |
| Cash & Equiv.Liquid assets | $61M | $680M | $41M | $81M | $902M |
| Total DebtShort + long-term debt | $27M | $224M | $18M | $55M | $72,000 |
| Interest CoverageEBIT ÷ Interest expense | -28.22x | -30.73x | -52.03x | -104.53x | — |
Total Returns (Dividends Reinvested)
Evenly matched — ANL and ZYME and IMVT each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $680 for CAN. Over the past 12 months, ANL leads with a +545.0% total return vs ZLAB's -60.3%. The 3-year compound annual growth rate (CAGR) favors ZYME at 39.9% vs CAN's -47.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +647.8% | -1.5% | -14.0% | -58.4% | +29.8% |
| 1-Year ReturnPast 12 months | +545.0% | -60.3% | +74.7% | -54.4% | +110.9% |
| 3-Year ReturnCumulative with dividends | -31.2% | -38.2% | +173.7% | -85.7% | +55.0% |
| 5-Year ReturnCumulative with dividends | -31.2% | -90.0% | -39.7% | -93.2% | +213.0% |
| 10-Year ReturnCumulative with dividends | -31.2% | -38.9% | +76.0% | -92.2% | +237.9% |
| CAGR (3Y)Annualised 3-year return | -11.7% | -14.8% | +39.9% | -47.7% | +15.7% |
Risk & Volatility
Evenly matched — ZYME and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
ZYME is the less volatile stock with a 0.87 beta — it tends to amplify market swings less than CAN's 4.24 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 92.7% from its 52-week high vs CAN's 14.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.39x | 1.15x | 0.87x | 4.24x | 1.66x |
| 52-Week HighHighest price in past year | $17.25 | $44.34 | $29.75 | $2.22 | $36.27 |
| 52-Week LowLowest price in past year | $0.88 | $15.96 | $11.51 | $0.31 | $14.32 |
| % of 52W HighCurrent price vs 52-week peak | +59.8% | +38.5% | +76.9% | +14.4% | +92.7% |
| RSI (14)Momentum oscillator 0–100 | 39.0 | 43.4 | 36.7 | 30.1 | 57.9 |
| Avg Volume (50D)Average daily shares traded | 380K | 842K | 584K | 9.7M | 1.9M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ANL as "Buy", ZLAB as "Buy", ZYME as "Buy", CAN as "Buy", IMVT as "Buy". Consensus price targets imply 337.2% upside for CAN (target: $1) vs 29.9% for IMVT (target: $44).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $26.00 | $35.00 | $40.67 | $1.40 | $43.67 |
| # AnalystsCovering analysts | 1 | 11 | 20 | 6 | 23 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | 0 | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +2.5% | 0.0% | 0.0% |
CAN leads in 1 of 6 categories (Valuation Metrics). IMVT leads in 1 (Profitability & Efficiency). 3 tied.
ANL vs ZLAB vs ZYME vs CAN vs IMVT: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is ANL or ZLAB or ZYME or CAN or IMVT a better buy right now?
For growth investors, Canaan Inc.
(CAN) is the stronger pick with 96. 7% revenue growth year-over-year, versus -100. 0% for Adlai Nortye Ltd. (ANL). Analysts rate Adlai Nortye Ltd. (ANL) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ANL or ZLAB or ZYME or CAN or IMVT?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +213. 0%, compared to -93. 2% for Canaan Inc. (CAN). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus CAN's -92. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ANL or ZLAB or ZYME or CAN or IMVT?
By beta (market sensitivity over 5 years), Zymeworks Inc.
(ZYME) is the lower-risk stock at 0. 87β versus Canaan Inc. 's 4. 24β — meaning CAN is approximately 389% more volatile than ZYME relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 107% for Adlai Nortye Ltd. — giving it more financial flexibility in a downturn.
04Which is growing faster — ANL or ZLAB or ZYME or CAN or IMVT?
By revenue growth (latest reported year), Canaan Inc.
(CAN) is pulling ahead at 96. 7% versus -100. 0% for Adlai Nortye Ltd. (ANL). On earnings-per-share growth, the picture is similar: Adlai Nortye Ltd. grew EPS 68. 3% year-over-year, compared to -1. 5% for Immunovant, Inc.. Over a 3-year CAGR, ZLAB leads at 28. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ANL or ZLAB or ZYME or CAN or IMVT?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -833. 1% for Adlai Nortye Ltd. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -996. 4% for ANL. At the gross margin level — before operating expenses — ANL leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is ANL or ZLAB or ZYME or CAN or IMVT more undervalued right now?
Analyst consensus price targets imply the most upside for CAN: 337.
2% to $1. 40.
07Which pays a better dividend — ANL or ZLAB or ZYME or CAN or IMVT?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is ANL or ZLAB or ZYME or CAN or IMVT better for a retirement portfolio?
For long-horizon retirement investors, Zymeworks Inc.
(ZYME) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 87)). Canaan Inc. (CAN) carries a higher beta of 4. 24 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ZYME: +76. 0%, CAN: -92. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between ANL and ZLAB and ZYME and CAN and IMVT?
These companies operate in different sectors (ANL (Healthcare) and ZLAB (Healthcare) and ZYME (Healthcare) and CAN (Technology) and IMVT (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: ANL is a small-cap quality compounder stock; ZLAB is a small-cap high-growth stock; ZYME is a small-cap high-growth stock; CAN is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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