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ANL
ZLAB logo
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CAN
IMVT logo
IMVT
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Stock Comparison

ANL vs ZLAB vs ZYME vs CAN vs IMVT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ANL
Adlai Nortye Ltd.

Biotechnology

HealthcareNASDAQ • KY
Market Cap$322M
5Y Perf.-31.2%
ZLAB
Zai Lab Limited

Biotechnology

HealthcareNASDAQ • CN
Market Cap$1.89B
5Y Perf.-29.8%
ZYME
Zymeworks Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$1.68B
5Y Perf.+260.9%
CAN
Canaan Inc.

Computer Hardware

TechnologyNASDAQ • SG
Market Cap$203M
5Y Perf.-82.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.-12.4%

ANL vs ZLAB vs ZYME vs CAN vs IMVT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ANL logoANL
ZLAB logoZLAB
ZYME logoZYME
CAN logoCAN
IMVT logoIMVT
IndustryBiotechnologyBiotechnologyBiotechnologyComputer HardwareBiotechnology
Market Cap$322M$1.89B$1.68B$203M$6.90B
Revenue (TTM)$6M$453M$81M$530M$0.00
Net Income (TTM)$-54M$-178M$-103M$-210M$-506M
Gross Margin100.0%57.9%94.4%7.8%
Operating Margin-10.0%-53.5%-140.4%-19.3%
Forward P/E15.5x
Total Debt$27M$224M$18M$55M$72K
Cash & Equiv.$61M$680M$41M$81M$902M

ANL vs ZLAB vs ZYME vs CAN vs IMVTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ANL
ZLAB
ZYME
CAN
IMVT
StockSep 23Jun 26Return
Adlai Nortye Ltd. (ANL)10068.8-31.2%
Zai Lab Limited (ZLAB)10070.2-29.8%
Zymeworks Inc. (ZYME)100360.9+260.9%
Canaan Inc. (CAN)10017.6-82.4%
Immunovant, Inc. (IMVT)10087.6-12.4%

Price return only. Dividends and distributions are not included.

Quick Verdict: ANL vs ZLAB vs ZYME vs CAN vs IMVT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ZYME leads in 2 of 6 categories (5-stock set), making it the strongest pick for capital preservation and lower volatility and operational efficiency and capital deployment. Adlai Nortye Ltd. is the stronger pick specifically for recent price momentum and sentiment. CAN and IMVT also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇ZYME emerged as the overall leader. Track its performance:
ANL
Adlai Nortye Ltd.
The Momentum Pick

ANL is the #2 pick in this set and the best alternative if momentum is your priority.

  • +5.5% vs ZLAB's -60.3%
Best for: momentum
ZLAB
Zai Lab Limited
The Healthcare Pick

Among these 5 stocks, ZLAB doesn't own a clear edge in any measured category.

Best for: healthcare exposure
ZYME
Zymeworks Inc.
The Income Pick

ZYME carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • beta 0.87
  • Lower volatility, beta 0.87, Low D/E 6.8%, current ratio 5.52x
  • Beta 0.87, current ratio 5.52x
  • Beta 0.87 vs CAN's 4.24, lower leverage
Best for: income & stability and sleep-well-at-night
CAN
Canaan Inc.
The Growth Play

CAN ranks third and is worth considering specifically for growth exposure.

  • Rev growth 96.7%, EPS growth 51.1%, 3Y rev CAGR -6.7%
  • 96.7% revenue growth vs ANL's -100.0%
Best for: growth exposure
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding.

  • 237.9% 10Y total return vs ZYME's 76.0%
  • 2.6% margin vs ANL's -8.3%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthCAN logoCAN96.7% revenue growth vs ANL's -100.0%
Quality / MarginsIMVT logoIMVT2.6% margin vs ANL's -8.3%
Stability / SafetyZYME logoZYMEBeta 0.87 vs CAN's 4.24, lower leverage
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)ANL logoANL+5.5% vs ZLAB's -60.3%
Efficiency (ROA)ZYME logoZYME-0.1% ROA vs IMVT's -62.2%

ANL vs ZLAB vs ZYME vs CAN vs IMVT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ANLAdlai Nortye Ltd.

Segment breakdown not available.

ZLABZai Lab Limited
FY 2025
Zejula
56.5%$189M
Nuzyra
18.2%$61M
Optune
14.4%$48M
Qinlock
10.6%$36M
Product and Service, Other
0.2%$717,000
ZYMEZymeworks Inc.
FY 2025
Milestone Revenue
61.6%$25M
Option Exercise Fee
18.5%$8M
Research Support Payments And Other Service
13.8%$6M
Royalty
6.1%$2M
CANCanaan Inc.
FY 2025
Product
78.5%$414M
Mining
21.5%$113M
IMVTImmunovant, Inc.

Segment breakdown not available.

ANL vs ZLAB vs ZYME vs CAN vs IMVT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCANLAGGINGZYME

Income & Cash Flow (Last 12 Months)

Evenly matched — ANL and ZLAB and CAN each lead in 2 of 6 comparable metrics.

CAN and IMVT operate at a comparable scale, with $530M and $0 in trailing revenue. Profitability is closely matched — net margins range from -39.3% (ZLAB) to -8.3% (ANL). On growth, CAN holds the edge at +121.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.
RevenueTrailing 12 months$6M$453M$81M$530M$0
EBITDAEarnings before interest/tax-$64M-$227M-$118M-$140M-$532M
Net IncomeAfter-tax profit-$54M-$178M-$103M-$210M-$506M
Free Cash FlowCash after capex-$67M-$129M-$45.7B$0-$407M
Gross MarginGross profit ÷ Revenue+100.0%+57.9%+94.4%+7.8%
Operating MarginEBIT ÷ Revenue-10.0%-53.5%-140.4%-19.3%
Net MarginNet income ÷ Revenue-8.3%-39.3%-126.3%-39.7%
FCF MarginFCF ÷ Revenue-10.3%-28.5%-563.0%
Rev. Growth (YoY)Latest quarter vs prior year-6.5%-91.1%+121.1%
EPS Growth (YoY)Latest quarter vs prior year+78.7%-11.1%-96.7%+59.4%-14.1%
Evenly matched — ANL and ZLAB and CAN each lead in 2 of 6 comparable metrics.

Valuation Metrics

CAN leads this category, winning 2 of 3 comparable metrics.
MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.
Market CapShares × price$322M$1.9B$1.7B$203M$6.9B
Enterprise ValueMkt cap + debt − cash$289M$1.4B$1.7B$177M$6.0B
Trailing P/EPrice ÷ TTM EPS-2.11x-10.67x-21.19x-0.71x-12.14x
Forward P/EPrice ÷ next-FY EPS est.15.46x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue4.11x15.89x0.38x
Price / BookPrice ÷ Book value/share4.31x2.61x6.42x0.34x7.19x
Price / FCFMarket cap ÷ FCF
CAN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

IMVT leads this category, winning 3 of 9 comparable metrics.

ZYME delivers a -0.2% return on equity — every $100 of shareholder capital generates $-0 in annual profit, vs $-101 for ANL. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ANL's 1.07x. On the Piotroski fundamental quality scale (0–9), CAN scores 6/9 vs IMVT's 2/9, reflecting solid financial health.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.
ROE (TTM)Return on equity-101.3%-24.3%-0.2%-60.7%-68.2%
ROA (TTM)Return on assets-50.2%-15.5%-0.1%-34.6%-62.2%
ROICReturn on invested capital-7.3%-41.7%-25.9%-24.9%
ROCEReturn on capital employed-103.8%-27.2%-27.3%-29.7%-68.3%
Piotroski ScoreFundamental quality 0–923562
Debt / EquityFinancial leverage1.07x0.31x0.07x0.13x0.00x
Net DebtTotal debt minus cash-$34M-$455M-$23M-$26M-$902M
Cash & Equiv.Liquid assets$61M$680M$41M$81M$902M
Total DebtShort + long-term debt$27M$224M$18M$55M$72,000
Interest CoverageEBIT ÷ Interest expense-28.22x-30.73x-52.03x-104.53x
IMVT leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — ANL and ZYME and IMVT each lead in 2 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $680 for CAN. Over the past 12 months, ANL leads with a +545.0% total return vs ZLAB's -60.3%. The 3-year compound annual growth rate (CAGR) favors ZYME at 39.9% vs CAN's -47.7% — a key indicator of consistent wealth creation.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.
YTD ReturnYear-to-date+647.8%-1.5%-14.0%-58.4%+29.8%
1-Year ReturnPast 12 months+545.0%-60.3%+74.7%-54.4%+110.9%
3-Year ReturnCumulative with dividends-31.2%-38.2%+173.7%-85.7%+55.0%
5-Year ReturnCumulative with dividends-31.2%-90.0%-39.7%-93.2%+213.0%
10-Year ReturnCumulative with dividends-31.2%-38.9%+76.0%-92.2%+237.9%
CAGR (3Y)Annualised 3-year return-11.7%-14.8%+39.9%-47.7%+15.7%
Evenly matched — ANL and ZYME and IMVT each lead in 2 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ZYME and IMVT each lead in 1 of 2 comparable metrics.

ZYME is the less volatile stock with a 0.87 beta — it tends to amplify market swings less than CAN's 4.24 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 92.7% from its 52-week high vs CAN's 14.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.
Beta (5Y)Sensitivity to S&P 5001.39x1.15x0.87x4.24x1.66x
52-Week HighHighest price in past year$17.25$44.34$29.75$2.22$36.27
52-Week LowLowest price in past year$0.88$15.96$11.51$0.31$14.32
% of 52W HighCurrent price vs 52-week peak+59.8%+38.5%+76.9%+14.4%+92.7%
RSI (14)Momentum oscillator 0–10039.043.436.730.157.9
Avg Volume (50D)Average daily shares traded380K842K584K9.7M1.9M
Evenly matched — ZYME and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: ANL as "Buy", ZLAB as "Buy", ZYME as "Buy", CAN as "Buy", IMVT as "Buy". Consensus price targets imply 337.2% upside for CAN (target: $1) vs 29.9% for IMVT (target: $44).

MetricANL logoANLAdlai Nortye Ltd.ZLAB logoZLABZai Lab LimitedZYME logoZYMEZymeworks Inc.CAN logoCANCanaan Inc.IMVT logoIMVTImmunovant, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$26.00$35.00$40.67$1.40$43.67
# AnalystsCovering analysts11120623
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+2.5%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

CAN leads in 1 of 6 categories (Valuation Metrics). IMVT leads in 1 (Profitability & Efficiency). 3 tied.

Best OverallCanaan Inc. (CAN)Leads 1 of 6 categories
Loading custom metrics...

ANL vs ZLAB vs ZYME vs CAN vs IMVT: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is ANL or ZLAB or ZYME or CAN or IMVT a better buy right now?

For growth investors, Canaan Inc.

(CAN) is the stronger pick with 96. 7% revenue growth year-over-year, versus -100. 0% for Adlai Nortye Ltd. (ANL). Analysts rate Adlai Nortye Ltd. (ANL) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ANL or ZLAB or ZYME or CAN or IMVT?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +213. 0%, compared to -93. 2% for Canaan Inc. (CAN). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus CAN's -92. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ANL or ZLAB or ZYME or CAN or IMVT?

By beta (market sensitivity over 5 years), Zymeworks Inc.

(ZYME) is the lower-risk stock at 0. 87β versus Canaan Inc. 's 4. 24β — meaning CAN is approximately 389% more volatile than ZYME relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 107% for Adlai Nortye Ltd. — giving it more financial flexibility in a downturn.

04

Which is growing faster — ANL or ZLAB or ZYME or CAN or IMVT?

By revenue growth (latest reported year), Canaan Inc.

(CAN) is pulling ahead at 96. 7% versus -100. 0% for Adlai Nortye Ltd. (ANL). On earnings-per-share growth, the picture is similar: Adlai Nortye Ltd. grew EPS 68. 3% year-over-year, compared to -1. 5% for Immunovant, Inc.. Over a 3-year CAGR, ZLAB leads at 28. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ANL or ZLAB or ZYME or CAN or IMVT?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -833. 1% for Adlai Nortye Ltd. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -996. 4% for ANL. At the gross margin level — before operating expenses — ANL leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is ANL or ZLAB or ZYME or CAN or IMVT more undervalued right now?

Analyst consensus price targets imply the most upside for CAN: 337.

2% to $1. 40.

07

Which pays a better dividend — ANL or ZLAB or ZYME or CAN or IMVT?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is ANL or ZLAB or ZYME or CAN or IMVT better for a retirement portfolio?

For long-horizon retirement investors, Zymeworks Inc.

(ZYME) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 87)). Canaan Inc. (CAN) carries a higher beta of 4. 24 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ZYME: +76. 0%, CAN: -92. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between ANL and ZLAB and ZYME and CAN and IMVT?

These companies operate in different sectors (ANL (Healthcare) and ZLAB (Healthcare) and ZYME (Healthcare) and CAN (Technology) and IMVT (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ANL is a small-cap quality compounder stock; ZLAB is a small-cap high-growth stock; ZYME is a small-cap high-growth stock; CAN is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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