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Stock Comparison

ATXS vs BCAB vs IMVT vs ALNY

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ATXS
Astria Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$718M
5Y Perf.-2.0%
BCAB
BioAtla, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5M
5Y Perf.-98.3%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.-45.0%
ALNY
Alnylam Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$39.48B
5Y Perf.+206.0%

ATXS vs BCAB vs IMVT vs ALNY — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ATXS logoATXS
BCAB logoBCAB
IMVT logoIMVT
ALNY logoALNY
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$718M$5M$5.53B$39.48B
Revenue (TTM)$706K$2M$0.00$4.29B
Net Income (TTM)$-124M$-60M$-464M$577M
Gross Margin100.0%100.0%80.9%
Operating Margin-193.4%-29.7%17.5%
Forward P/E44.2x
Total Debt$5M$6M$98K$1.28B
Cash & Equiv.$60M$7M$714M$1.66B

ATXS vs BCAB vs IMVT vs ALNYLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ATXS
BCAB
IMVT
ALNY
StockDec 20Jan 26Return
Astria Therapeutics… (ATXS)10098.0-2.0%
BioAtla, Inc. (BCAB)1001.7-98.3%
Immunovant, Inc. (IMVT)10055.0-45.0%
Alnylam Pharmaceuti… (ALNY)100306.0+206.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: ATXS vs BCAB vs IMVT vs ALNY

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ALNY leads in 3 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Astria Therapeutics, Inc. is the stronger pick specifically for recent price momentum and sentiment. BCAB also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
ATXS
Astria Therapeutics, Inc.
The Defensive Pick

ATXS is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 1.32, Low D/E 1.7%, current ratio 17.49x
  • Beta 1.32, current ratio 17.49x
  • +184.6% vs BCAB's -80.6%
Best for: sleep-well-at-night and defensive
BCAB
BioAtla, Inc.
The Income Pick

BCAB is the clearest fit if your priority is income & stability.

  • beta 0.51
  • Beta 0.51 vs IMVT's 1.37
Best for: income & stability
IMVT
Immunovant, Inc.
The Secondary Option

IMVT lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ALNY
Alnylam Pharmaceuticals, Inc.
The Growth Play

ALNY carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 65.2%, EPS growth 206.9%, 3Y rev CAGR 53.0%
  • 411.9% 10Y total return vs IMVT's 173.6%
  • 65.2% revenue growth vs BCAB's -81.8%
  • 13.5% margin vs ATXS's -175.7%
Best for: growth exposure and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthALNY logoALNY65.2% revenue growth vs BCAB's -81.8%
Quality / MarginsALNY logoALNY13.5% margin vs ATXS's -175.7%
Stability / SafetyBCAB logoBCABBeta 0.51 vs IMVT's 1.37
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)ATXS logoATXS+184.6% vs BCAB's -80.6%
Efficiency (ROA)ALNY logoALNY11.8% ROA vs BCAB's -250.6%

ATXS vs BCAB vs IMVT vs ALNY — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ATXSAstria Therapeutics, Inc.

Segment breakdown not available.

BCABBioAtla, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

ALNYAlnylam Pharmaceuticals, Inc.
FY 2025
GIVLAARI
64.1%$308M
ONPATTRO
35.9%$173M

ATXS vs BCAB vs IMVT vs ALNY — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLALNYLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

ALNY leads this category, winning 4 of 5 comparable metrics.

ALNY and IMVT operate at a comparable scale, with $4.3B and $0 in trailing revenue. ALNY is the more profitable business, keeping 13.5% of every revenue dollar as net income compared to ATXS's -175.7%.

MetricATXS logoATXSAstria Therapeuti…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.ALNY logoALNYAlnylam Pharmaceu…
RevenueTrailing 12 months$706,000$2M$0$4.3B
EBITDAEarnings before interest/tax-$134M-$59M-$487M$677M
Net IncomeAfter-tax profit-$124M-$60M-$464M$577M
Free Cash FlowCash after capex-$120M-$34M-$423M$641M
Gross MarginGross profit ÷ Revenue+100.0%+100.0%+80.9%
Operating MarginEBIT ÷ Revenue-193.4%-29.7%+17.5%
Net MarginNet income ÷ Revenue-175.7%-29.8%+13.5%
FCF MarginFCF ÷ Revenue-170.4%-17.0%+15.0%
Rev. Growth (YoY)Latest quarter vs prior year+96.4%
EPS Growth (YoY)Latest quarter vs prior year-27.9%+46.7%+19.7%+4.4%
ALNY leads this category, winning 4 of 5 comparable metrics.

Valuation Metrics

Evenly matched — ATXS and BCAB and IMVT each lead in 1 of 3 comparable metrics.
MetricATXS logoATXSAstria Therapeuti…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.ALNY logoALNYAlnylam Pharmaceu…
Market CapShares × price$718M$5M$5.5B$39.5B
Enterprise ValueMkt cap + debt − cash$664M$4M$4.8B$39.1B
Trailing P/EPrice ÷ TTM EPS-7.49x-0.09x-9.97x127.00x
Forward P/EPrice ÷ next-FY EPS est.44.18x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple70.17x
Price / SalesMarket cap ÷ Revenue2.56x10.63x
Price / BookPrice ÷ Book value/share2.21x5.83x50.50x
Price / FCFMarket cap ÷ FCF84.84x
Evenly matched — ATXS and BCAB and IMVT each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

ALNY leads this category, winning 5 of 8 comparable metrics.

ALNY delivers a 98.3% return on equity — every $100 of shareholder capital generates $98 in annual profit, vs $-53 for ATXS. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALNY's 1.62x. On the Piotroski fundamental quality scale (0–9), ALNY scores 6/9 vs ATXS's 1/9, reflecting solid financial health.

MetricATXS logoATXSAstria Therapeuti…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.ALNY logoALNYAlnylam Pharmaceu…
ROE (TTM)Return on equity-53.2%-47.1%+98.3%
ROA (TTM)Return on assets-45.6%-2.5%-44.1%+11.8%
ROICReturn on invested capital-50.3%+33.4%
ROCEReturn on capital employed-39.4%-4.0%-66.1%+15.3%
Piotroski ScoreFundamental quality 0–91226
Debt / EquityFinancial leverage0.02x0.00x1.62x
Net DebtTotal debt minus cash-$54M-$918,000-$714M-$379M
Cash & Equiv.Liquid assets$60M$7M$714M$1.7B
Total DebtShort + long-term debt$5M$6M$98,000$1.3B
Interest CoverageEBIT ÷ Interest expense2.02x
ALNY leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

ALNY leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in ALNY five years ago would be worth $22,537 today (with dividends reinvested), compared to $19 for BCAB. Over the past 12 months, ATXS leads with a +184.6% total return vs BCAB's -80.6%. The 3-year compound annual growth rate (CAGR) favors ALNY at 12.1% vs BCAB's -70.1% — a key indicator of consistent wealth creation.

MetricATXS logoATXSAstria Therapeuti…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.ALNY logoALNYAlnylam Pharmaceu…
YTD ReturnYear-to-date-2.4%-83.7%+5.1%-26.1%
1-Year ReturnPast 12 months+184.6%-80.6%+96.1%+7.0%
3-Year ReturnCumulative with dividends-0.4%-97.3%+40.9%+40.9%
5-Year ReturnCumulative with dividends+7.0%-99.8%+62.4%+125.4%
10-Year ReturnCumulative with dividends-95.5%-99.7%+173.6%+411.9%
CAGR (3Y)Annualised 3-year return-0.1%-70.1%+12.1%+12.1%
ALNY leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ATXS and BCAB each lead in 1 of 2 comparable metrics.

BCAB is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than IMVT's 1.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ATXS currently trades 94.7% from its 52-week high vs BCAB's 6.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricATXS logoATXSAstria Therapeuti…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.ALNY logoALNYAlnylam Pharmaceu…
Beta (5Y)Sensitivity to S&P 5001.32x0.51x1.37x0.71x
52-Week HighHighest price in past year$13.29$71.50$30.09$495.55
52-Week LowLowest price in past year$3.69$0.33$13.36$245.96
% of 52W HighCurrent price vs 52-week peak+94.7%+6.1%+90.5%+59.7%
RSI (14)Momentum oscillator 0–10046.140.560.243.8
Avg Volume (50D)Average daily shares traded1.6M40K1.4M1.1M
Evenly matched — ATXS and BCAB each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: ATXS as "Hold", BCAB as "Buy", IMVT as "Buy", ALNY as "Buy". Consensus price targets imply 5647.1% upside for BCAB (target: $250) vs 50.6% for ALNY (target: $446).

MetricATXS logoATXSAstria Therapeuti…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.ALNY logoALNYAlnylam Pharmaceu…
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuy
Price TargetConsensus 12-month target$19.40$250.00$45.50$445.67
# AnalystsCovering analysts892352
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

ALNY leads in 3 of 6 categories — strongest in Income & Cash Flow and Profitability & Efficiency. 2 categories are tied.

Best OverallAlnylam Pharmaceuticals, In… (ALNY)Leads 3 of 6 categories
Loading custom metrics...

ATXS vs BCAB vs IMVT vs ALNY: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is ATXS or BCAB or IMVT or ALNY a better buy right now?

For growth investors, Alnylam Pharmaceuticals, Inc.

(ALNY) is the stronger pick with 65. 2% revenue growth year-over-year, versus -81. 8% for BioAtla, Inc. (BCAB). Alnylam Pharmaceuticals, Inc. (ALNY) offers the better valuation at 127. 0x trailing P/E (44. 2x forward), making it the more compelling value choice. Analysts rate BioAtla, Inc. (BCAB) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ATXS or BCAB or IMVT or ALNY?

Over the past 5 years, Alnylam Pharmaceuticals, Inc.

(ALNY) delivered a total return of +125. 4%, compared to -99. 8% for BioAtla, Inc. (BCAB). Over 10 years, the gap is even starker: ALNY returned +411. 9% versus BCAB's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ATXS or BCAB or IMVT or ALNY?

By beta (market sensitivity over 5 years), BioAtla, Inc.

(BCAB) is the lower-risk stock at 0. 51β versus Immunovant, Inc. 's 1. 37β — meaning IMVT is approximately 169% more volatile than BCAB relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 162% for Alnylam Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — ATXS or BCAB or IMVT or ALNY?

By revenue growth (latest reported year), Alnylam Pharmaceuticals, Inc.

(ALNY) is pulling ahead at 65. 2% versus -81. 8% for BioAtla, Inc. (BCAB). On earnings-per-share growth, the picture is similar: Alnylam Pharmaceuticals, Inc. grew EPS 206. 9% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ATXS or BCAB or IMVT or ALNY?

Alnylam Pharmaceuticals, Inc.

(ALNY) is the more profitable company, earning 8. 4% net margin versus -175. 7% for Astria Therapeutics, Inc. — meaning it keeps 8. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ALNY leads at 13. 5% versus -193. 4% for ATXS. At the gross margin level — before operating expenses — ATXS leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is ATXS or BCAB or IMVT or ALNY more undervalued right now?

Analyst consensus price targets imply the most upside for BCAB: 5647.

1% to $250. 00.

07

Which pays a better dividend — ATXS or BCAB or IMVT or ALNY?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is ATXS or BCAB or IMVT or ALNY better for a retirement portfolio?

For long-horizon retirement investors, Alnylam Pharmaceuticals, Inc.

(ALNY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 71), +411. 9% 10Y return). Both have compounded well over 10 years (ALNY: +411. 9%, ATXS: -95. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between ATXS and BCAB and IMVT and ALNY?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ATXS is a small-cap quality compounder stock; BCAB is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ALNY is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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