Alnylam Pharmaceuticals, Inc. (ALNY) Revenue History
Annual and quarterly revenue from 2002 to present
ALNY Revenue Over Time (2002–2025)
ALNY Revenue Growth History
16 of 22 years with positive growth- FY2002 revenue growth
- N/A
- FY2003 revenue growth
- N/A
- FY2004 revenue growth
- +2330.7%
- FY2005 revenue growth
- +33.6%
- FY2006 revenue growth
- +371.1%
- FY2007 revenue growth
- +89.0%
- FY2008 revenue growth
- +88.9%
- FY2009 revenue growth
- +4.5%
- FY2010 revenue growth
- -0.5%
- FY2011 revenue growth
- -17.3%
- FY2012 revenue growth
- -19.4%
- FY2013 revenue growth
- -29.3%
- FY2014 revenue growth
- +7.2%
- FY2015 revenue growth
- -18.7%
- FY2016 revenue growth
- +14.8%
- FY2017 revenue growth
- +90.7%
- FY2018 revenue growth
- -16.7%
- FY2019 revenue growth
- +193.4%
- FY2020 revenue growth
- +124.3%
- FY2021 revenue growth
- +71.3%
- FY2022 revenue growth
- +22.9%
- FY2023 revenue growth
- +76.2%
- FY2024 revenue growth
- +23.0%
- FY2025 revenue growth
- +65.2%
| Quarter | Revenue | YoY |
|---|---|---|
| Q1 2026 | $1.17B | +96.4% |
| Q4 2025 | $1.10B | +84.9% |
| Q3 2025 | $1.25B | +149.3% |
| Q2 2025 | $773.7M | +17.3% |
| Q1 2025 | $594.2M | +20.2% |
| Q4 2024 | $593.2M | +34.9% |
| Q3 2024 | $500.9M | -33.3% |
| Q2 2024 | $659.8M | +107.0% |
Multi-year avg. share of annual revenue by fiscal quarter
Revenue Breakdown (FY 2025)
ALNY's revenue distribution by segment and geography for fiscal year 2025
By Product/Segment
By Geography
ALNY Revenue Analysis (2002–2025)
Current Revenue & Growth
As of June 21, 2026, Alnylam Pharmaceuticals, Inc. (ALNY) generated trailing twelve-month (TTM) revenue of $4.29 billion, reflecting explosive growth of +96.4% year-over-year. The most recent quarter (Q1 2026) recorded $1.17 billion in revenue, up 6.4% sequentially.
Historical Growth Trajectory
ALNY's 5-year compound annual growth rate (CAGR) stands at +49.8%, indicating outstanding long-term growth trajectory. The 3-year CAGR of +53.0% exceeds the 5-year average, indicating an acceleration in the most recent period. Alnylam Pharmaceuticals, Inc.'s highest annual revenue of $3.71 billion was recorded in 2025, an all-time high.
Revenue by Segment
ALNY's revenue is primarily driven by GIVLAARI (64%), and ONPATTRO (36%). With over half of revenue concentrated in GIVLAARI, the company has a focused business model while developing other growth vectors.
Peer Comparison
Compared to Healthcare sector peers — including IONS (+47.5% YoY), ARWR (+14.1% YoY), and NTLA (+45.0% YoY) — ALNY has outperformed the peer group in revenue growth. Compare ALNY vs IONS →
ALNY Revenue vs Peers
Revenue metrics vs comparable public companies
| Company | TTM Revenue | YoY Growth | 5Y CAGR | Op. Margin | Compare |
|---|---|---|---|---|---|
| ALNYCurrent | $4.3B | +96.4% | +49.8% | 13.5% | |
 IONS | $944M | +47.5% | +5.3% | -40.5% | |
 ARWR | $829M | +14.1% | +56.6% | 11.9% | |
 NTLA | $68M | +45.0% | +3.1% | -651.7% | |
 BEAM | $140M | +108.0% | +466.3% | -274.6% | |
 MRNA | $1.9B | -29.1% | +19.3% | -158.1% |
ALNY Historical Revenue Data (2002–2025)
| Year | Revenue | YoY % | Gross Profit | Gross Margin | Op. Income | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $3.71B | +65.2% | $3.04B | 81.8% | $501.6M | 13.5% |
| 2024 | $2.25B | +23.0% | $1.92B | 85.6% | $-176,885,000 | -7.9% |
| 2023 | $1.83B | +76.2% | $1.52B | 83.0% | $-282,175,000 | -15.4% |
| 2022 | $1.04B | +22.9% | $868.6M | 83.7% | $-785,072,000 | -75.7% |
| 2021 | $844.3M | +71.3% | $704.1M | 83.4% | $-708,652,000 | -83.9% |
| 2020 | $492.9M | +124.3% | $414.8M | 84.2% | $-828,438,000 | -168.1% |
| 2019 | $219.8M | +193.4% | $194.7M | 88.6% | $-939,431,000 | -427.5% |
| 2018 | $74.9M | -16.7% | $73.1M | 97.6% | $-814,673,000 | -1087.6% |
| 2017 | $89.9M | +90.7% | $76.5M | 85.1% | $-500,088,000 | -556.2% |
| 2016 | $47.2M | +14.8% | $47.2M | 100.0% | $-424,587,000 | -900.3% |
| 2015 | $41.1M | -18.7% | $41.1M | 100.0% | $-296,008,000 | -720.3% |
| 2014 | $50.6M | +7.2% | $50.6M | 100.0% | $-404,980,000 | -801.0% |
| 2013 | $47.2M | -29.3% | $47.2M | 100.0% | $-92,942,000 | -197.0% |
| 2012 | $66.7M | -19.4% | $66.7M | 100.0% | $-129,456,000 | -194.0% |
| 2011 | $82.8M | -17.3% | $82.8M | 100.0% | $-54,818,000 | -66.2% |
Full Stock Analysis
Deep dive into ALNY consensus models and risk factors.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
24+ years return with dividends reinvested.
DCA Calculator
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Peer Comparison
Compare growth, multiples, and margins vs sector.
ALNY — Frequently Asked Questions
Quick answers to the most common questions about buying ALNY stock.
Is ALNY's revenue growth accelerating or slowing?
ALNY revenue growth is accelerating. TTM revenue reached $4.3B, up +96.4% year-over-year — ahead of the 5-year CAGR of +49.8%. This indicates the business is expanding faster than its historical baseline.
What is ALNY's revenue history from 2002 to 2026?
Alnylam Pharmaceuticals, Inc. (ALNY) revenue history spans 2002 to 2026. TTM revenue as of 2026 is $4.3B, growing at +96.4% YoY. The 5-year CAGR is +49.8%. Complete annual and quarterly revenue figures are available on this page, including gross profit, operating income, and margin trends.
What is ALNY's long-term revenue growth rate (CAGR)?
Alnylam Pharmaceuticals, Inc.'s 5-year revenue CAGR of +49.8% reflects the sustained nature of its business expansion. As of 2026, the current YoY growth rate of +96.4% is above this long-term average. CAGR is the most reliable measure of sustained revenue momentum for ALNY.
Why does ALNY's quarterly revenue fluctuate?
ALNY quarterly revenue can fluctuate significantly between periods. A quarter-over-quarter (QoQ) change does not always indicate a trend; comparing the same quarter year-over-year (YoY) is a more reliable signal for underlying growth. Alnylam Pharmaceuticals, Inc.'s revenue data from 2002 to 2026 shows full historical quarterly detail on this page.
How is ALNY's revenue distributed by segment?
ALNY reports revenue broken down by product line and geographic region. The segment breakdown on this page shows which business units contribute the most to total revenue as of the latest fiscal year. Concentration in a single segment above 50% indicates category dependence, while a diversified mix signals more resilient revenue streams.
How does ALNY's revenue compare to industry peers?
Alnylam Pharmaceuticals, Inc. (ALNY) with TTM revenue of $4.3B and +96.4% YoY growth can be benchmarked against sector peers using the comparison table on this page. Revenue growth relative to peers indicates market share gains or losses. The peer section shows TTM revenue, YoY growth, and operating margin for direct comparisons.