Drug Manufacturers - Specialty & Generic
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AYTU vs ASRT vs SUPN vs PAHC
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
AYTU vs ASRT vs SUPN vs PAHC — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic |
| Market Cap | $16M | $144M | $3.01B | $1.75B |
| Revenue (TTM) | $63M | $119M | $777M | $1.46B |
| Net Income (TTM) | $-24M | $-30M | $-29M | $92M |
| Gross Margin | 66.0% | 70.2% | 89.4% | 31.9% |
| Operating Margin | -13.9% | -18.1% | -5.5% | 11.6% |
| Forward P/E | — | — | 24.1x | 14.2x |
| Total Debt | $23M | $39M | $41M | $762M |
| Cash & Equiv. | $31M | $10M | $128M | $68M |
AYTU vs ASRT vs SUPN vs PAHC — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Aytu BioPharma, Inc. (AYTU) | 100 | 0.8 | -99.2% |
| Assertio Holdings, … (ASRT) | 100 | 564.9 | +464.9% |
| Supernus Pharmaceut… (SUPN) | 100 | 216.7 | +116.7% |
| Phibro Animal Healt… (PAHC) | 100 | 164.7 | +64.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: AYTU vs ASRT vs SUPN vs PAHC
Each card shows where this stock fits in a portfolio — not just who wins on paper.
AYTU plays a supporting role in this comparison — it may shine differently against other peers.
ASRT is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.
- beta 0.72
- Lower volatility, beta 0.72, Low D/E 41.6%, current ratio 1.70x
- Beta 0.72, current ratio 1.70x
- Beta 0.72 vs PAHC's 1.38, lower leverage
SUPN is the clearest fit if your priority is long-term compounding.
- 228.4% 10Y total return vs ASRT's -68.7%
PAHC carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 27.4%, EPS growth 18.8%, 3Y rev CAGR 11.2%
- 27.4% revenue growth vs ASRT's -5.0%
- Lower P/E (14.2x vs 24.1x)
- 6.3% margin vs AYTU's -39.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 27.4% revenue growth vs ASRT's -5.0% | |
| Value | Lower P/E (14.2x vs 24.1x) | |
| Quality / Margins | 6.3% margin vs AYTU's -39.0% | |
| Stability / Safety | Beta 0.72 vs PAHC's 1.38, lower leverage | |
| Dividends | 1.1% yield; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +35.3% vs SUPN's +69.0% | |
| Efficiency (ROA) | 6.7% ROA vs AYTU's -20.0%, ROIC 9.8% vs -33.5% |
AYTU vs ASRT vs SUPN vs PAHC — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
AYTU vs ASRT vs SUPN vs PAHC — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
PAHC leads in 2 of 6 categories
ASRT leads 2 • AYTU leads 0 • SUPN leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — SUPN and PAHC each lead in 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
PAHC is the larger business by revenue, generating $1.5B annually — 23.4x AYTU's $63M. PAHC is the more profitable business, keeping 6.3% of every revenue dollar as net income compared to AYTU's -39.0%. On growth, SUPN holds the edge at +38.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $63M | $119M | $777M | $1.5B |
| EBITDAEarnings before interest/tax | -$4M | $8M | $29M | $220M |
| Net IncomeAfter-tax profit | -$24M | -$30M | -$29M | $92M |
| Free Cash FlowCash after capex | -$698,000 | -$28M | $82M | $47M |
| Gross MarginGross profit ÷ Revenue | +66.0% | +70.2% | +89.4% | +31.9% |
| Operating MarginEBIT ÷ Revenue | -13.9% | -18.1% | -5.5% | +11.6% |
| Net MarginNet income ÷ Revenue | -39.0% | -24.9% | -3.7% | +6.3% |
| FCF MarginFCF ÷ Revenue | -1.1% | -23.7% | +10.6% | +3.2% |
| Rev. Growth (YoY)Latest quarter vs prior year | -6.5% | -57.9% | +38.6% | +20.9% |
| EPS Growth (YoY)Latest quarter vs prior year | -3.0% | -12.7% | +81.0% | +7.4% |
Valuation Metrics
PAHC leads this category, winning 3 of 6 comparable metrics.
Valuation Metrics
On an enterprise value basis, PAHC's 15.7x EV/EBITDA is more attractive than SUPN's 53.4x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $16M | $144M | $3.0B | $1.7B |
| Enterprise ValueMkt cap + debt − cash | $7M | $173M | $2.9B | $2.4B |
| Trailing P/EPrice ÷ TTM EPS | -1.14x | -4.72x | -76.88x | 36.27x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 24.12x | 14.23x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 4.85x |
| EV / EBITDAEnterprise value multiple | — | 20.37x | 53.44x | 15.65x |
| Price / SalesMarket cap ÷ Revenue | 0.23x | 1.21x | 4.19x | 1.35x |
| Price / BookPrice ÷ Book value/share | 0.82x | 1.52x | 2.78x | 6.15x |
| Price / FCFMarket cap ÷ FCF | — | — | 65.45x | 41.82x |
Profitability & Efficiency
PAHC leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
PAHC delivers a 30.8% return on equity — every $100 of shareholder capital generates $31 in annual profit, vs $-172 for AYTU. SUPN carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to PAHC's 2.67x. On the Piotroski fundamental quality scale (0–9), PAHC scores 5/9 vs ASRT's 3/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -172.1% | -29.4% | -2.7% | +30.8% |
| ROA (TTM)Return on assets | -20.0% | -10.3% | -2.0% | +6.7% |
| ROICReturn on invested capital | -33.5% | -13.8% | -2.8% | +9.8% |
| ROCEReturn on capital employed | -13.3% | -13.9% | -3.4% | +12.0% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 3 | 4 | 5 |
| Debt / EquityFinancial leverage | 1.21x | 0.42x | 0.04x | 2.67x |
| Net DebtTotal debt minus cash | -$8M | $29M | -$87M | $694M |
| Cash & Equiv.Liquid assets | $31M | $10M | $128M | $68M |
| Total DebtShort + long-term debt | $23M | $39M | $41M | $762M |
| Interest CoverageEBIT ÷ Interest expense | -7.96x | -4.45x | — | 3.64x |
Total Returns (Dividends Reinvested)
ASRT leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ASRT five years ago would be worth $98,114 today (with dividends reinvested), compared to $215 for AYTU. Over the past 12 months, ASRT leads with a +3525.0% total return vs SUPN's +69.0%. The 3-year compound annual growth rate (CAGR) favors ASRT at 52.9% vs AYTU's 12.0% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -10.8% | +144.7% | +5.7% | +16.0% |
| 1-Year ReturnPast 12 months | +104.1% | +3525.0% | +69.0% | +125.1% |
| 3-Year ReturnCumulative with dividends | +40.3% | +257.3% | +42.1% | +210.4% |
| 5-Year ReturnCumulative with dividends | -97.8% | +881.1% | +78.0% | +66.0% |
| 10-Year ReturnCumulative with dividends | -100.0% | -68.7% | +228.4% | +128.6% |
| CAGR (3Y)Annualised 3-year return | +12.0% | +52.9% | +12.4% | +45.9% |
Risk & Volatility
ASRT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ASRT is the less volatile stock with a 0.72 beta — it tends to amplify market swings less than PAHC's 1.38 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ASRT currently trades 99.4% from its 52-week high vs PAHC's 71.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.27x | 0.72x | 0.78x | 1.38x |
| 52-Week HighHighest price in past year | $3.07 | $22.50 | $59.68 | $60.08 |
| 52-Week LowLowest price in past year | $1.20 | $0.58 | $29.16 | $19.00 |
| % of 52W HighCurrent price vs 52-week peak | +80.5% | +99.4% | +87.6% | +71.8% |
| RSI (14)Momentum oscillator 0–100 | 48.9 | 86.4 | 57.9 | 60.3 |
| Avg Volume (50D)Average daily shares traded | 42K | 247K | 604K | 302K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ASRT as "Hold", SUPN as "Buy", PAHC as "Buy". Consensus price targets imply 14.8% upside for SUPN (target: $60) vs -19.5% for ASRT (target: $18). PAHC is the only dividend payer here at 1.11% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | — | $18.00 | $60.00 | $49.00 |
| # AnalystsCovering analysts | — | 18 | 14 | 13 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +1.1% |
| Dividend StreakConsecutive years of raises | — | — | — | 0 |
| Dividend / ShareAnnual DPS | — | — | — | $0.48 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
PAHC leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). ASRT leads in 2 (Total Returns, Risk & Volatility). 1 tied.
AYTU vs ASRT vs SUPN vs PAHC: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is AYTU or ASRT or SUPN or PAHC a better buy right now?
For growth investors, Phibro Animal Health Corporation (PAHC) is the stronger pick with 27.
4% revenue growth year-over-year, versus -5. 0% for Assertio Holdings, Inc. (ASRT). Phibro Animal Health Corporation (PAHC) offers the better valuation at 36. 3x trailing P/E (14. 2x forward), making it the more compelling value choice. Analysts rate Supernus Pharmaceuticals, Inc. (SUPN) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — AYTU or ASRT or SUPN or PAHC?
On forward P/E, Phibro Animal Health Corporation is actually cheaper at 14.
2x.
03Which is the better long-term investment — AYTU or ASRT or SUPN or PAHC?
Over the past 5 years, Assertio Holdings, Inc.
(ASRT) delivered a total return of +881. 1%, compared to -97. 8% for Aytu BioPharma, Inc. (AYTU). Over 10 years, the gap is even starker: SUPN returned +228. 4% versus AYTU's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — AYTU or ASRT or SUPN or PAHC?
By beta (market sensitivity over 5 years), Assertio Holdings, Inc.
(ASRT) is the lower-risk stock at 0. 72β versus Phibro Animal Health Corporation's 1. 38β — meaning PAHC is approximately 91% more volatile than ASRT relative to the S&P 500. On balance sheet safety, Supernus Pharmaceuticals, Inc. (SUPN) carries a lower debt/equity ratio of 4% versus 3% for Phibro Animal Health Corporation — giving it more financial flexibility in a downturn.
05Which is growing faster — AYTU or ASRT or SUPN or PAHC?
By revenue growth (latest reported year), Phibro Animal Health Corporation (PAHC) is pulling ahead at 27.
4% versus -5. 0% for Assertio Holdings, Inc. (ASRT). On earnings-per-share growth, the picture is similar: Phibro Animal Health Corporation grew EPS 1883% year-over-year, compared to -151. 5% for Supernus Pharmaceuticals, Inc.. Over a 3-year CAGR, PAHC leads at 11. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — AYTU or ASRT or SUPN or PAHC?
Phibro Animal Health Corporation (PAHC) is the more profitable company, earning 3.
7% net margin versus -24. 9% for Assertio Holdings, Inc. — meaning it keeps 3. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PAHC leads at 8. 5% versus -18. 1% for ASRT. At the gross margin level — before operating expenses — SUPN leads at 89. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is AYTU or ASRT or SUPN or PAHC more undervalued right now?
On forward earnings alone, Phibro Animal Health Corporation (PAHC) trades at 14.
2x forward P/E versus 24. 1x for Supernus Pharmaceuticals, Inc. — 9. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for SUPN: 14. 8% to $60. 00.
08Which pays a better dividend — AYTU or ASRT or SUPN or PAHC?
In this comparison, PAHC (1.
1% yield) pays a dividend. AYTU, ASRT, SUPN do not pay a meaningful dividend and should not be held primarily for income.
09Is AYTU or ASRT or SUPN or PAHC better for a retirement portfolio?
For long-horizon retirement investors, Supernus Pharmaceuticals, Inc.
(SUPN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 78), +228. 4% 10Y return). Both have compounded well over 10 years (SUPN: +228. 4%, AYTU: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between AYTU and ASRT and SUPN and PAHC?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: AYTU is a small-cap quality compounder stock; ASRT is a small-cap quality compounder stock; SUPN is a small-cap quality compounder stock; PAHC is a small-cap high-growth stock. PAHC pays a dividend while AYTU, ASRT, SUPN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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