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Stock Comparison

AYTU vs ASRT vs SUPN vs PAHC

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
AYTU
Aytu BioPharma, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$16M
5Y Perf.-99.2%
ASRT
Assertio Holdings, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$144M
5Y Perf.+464.9%
SUPN
Supernus Pharmaceuticals, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$3.01B
5Y Perf.+116.7%
PAHC
Phibro Animal Health Corporation

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$1.75B
5Y Perf.+64.7%

AYTU vs ASRT vs SUPN vs PAHC — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
AYTU logoAYTU
ASRT logoASRT
SUPN logoSUPN
PAHC logoPAHC
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & GenericDrug Manufacturers - Specialty & Generic
Market Cap$16M$144M$3.01B$1.75B
Revenue (TTM)$63M$119M$777M$1.46B
Net Income (TTM)$-24M$-30M$-29M$92M
Gross Margin66.0%70.2%89.4%31.9%
Operating Margin-13.9%-18.1%-5.5%11.6%
Forward P/E24.1x14.2x
Total Debt$23M$39M$41M$762M
Cash & Equiv.$31M$10M$128M$68M

AYTU vs ASRT vs SUPN vs PAHCLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

AYTU
ASRT
SUPN
PAHC
StockMay 20May 26Return
Aytu BioPharma, Inc. (AYTU)1000.8-99.2%
Assertio Holdings, … (ASRT)100564.9+464.9%
Supernus Pharmaceut… (SUPN)100216.7+116.7%
Phibro Animal Healt… (PAHC)100164.7+64.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: AYTU vs ASRT vs SUPN vs PAHC

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: PAHC leads in 5 of 7 categories, making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Assertio Holdings, Inc. is the stronger pick specifically for capital preservation and lower volatility and recent price momentum and sentiment. As sector peers, any of these can serve as alternatives in the same allocation.
AYTU
Aytu BioPharma, Inc.
The Specific-Use Pick

AYTU plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
ASRT
Assertio Holdings, Inc.
The Income Pick

ASRT is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 0.72
  • Lower volatility, beta 0.72, Low D/E 41.6%, current ratio 1.70x
  • Beta 0.72, current ratio 1.70x
  • Beta 0.72 vs PAHC's 1.38, lower leverage
Best for: income & stability and sleep-well-at-night
SUPN
Supernus Pharmaceuticals, Inc.
The Long-Run Compounder

SUPN is the clearest fit if your priority is long-term compounding.

  • 228.4% 10Y total return vs ASRT's -68.7%
Best for: long-term compounding
PAHC
Phibro Animal Health Corporation
The Growth Play

PAHC carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 27.4%, EPS growth 18.8%, 3Y rev CAGR 11.2%
  • 27.4% revenue growth vs ASRT's -5.0%
  • Lower P/E (14.2x vs 24.1x)
  • 6.3% margin vs AYTU's -39.0%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthPAHC logoPAHC27.4% revenue growth vs ASRT's -5.0%
ValuePAHC logoPAHCLower P/E (14.2x vs 24.1x)
Quality / MarginsPAHC logoPAHC6.3% margin vs AYTU's -39.0%
Stability / SafetyASRT logoASRTBeta 0.72 vs PAHC's 1.38, lower leverage
DividendsPAHC logoPAHC1.1% yield; the other 3 pay no meaningful dividend
Momentum (1Y)ASRT logoASRT+35.3% vs SUPN's +69.0%
Efficiency (ROA)PAHC logoPAHC6.7% ROA vs AYTU's -20.0%, ROIC 9.8% vs -33.5%

AYTU vs ASRT vs SUPN vs PAHC — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

AYTUAytu BioPharma, Inc.
FY 2024
Consumer Health
100.0%$16M
ASRTAssertio Holdings, Inc.
FY 2025
Product
74.9%$117M
INDOCIN Products
12.1%$19M
Product, Other
6.8%$11M
SPRIX Nasal Spray
5.1%$8M
Royalty
1.0%$2M
SUPNSupernus Pharmaceuticals, Inc.
FY 2025
Product
47.2%$627M
Qelbree
22.9%$305M
GOCOVRI
11.1%$147M
Collaboration Revenue
4.0%$53M
APOKYN
3.6%$48M
Trokendi Xr
3.2%$42M
Oxtellar X R
3.1%$41M
Other (2)
5.0%$66M
PAHCPhibro Animal Health Corporation
FY 2025
Vaccines
100.0%$137M

AYTU vs ASRT vs SUPN vs PAHC — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLASRTLAGGINGSUPN

Income & Cash Flow (Last 12 Months)

Evenly matched — SUPN and PAHC each lead in 3 of 6 comparable metrics.

PAHC is the larger business by revenue, generating $1.5B annually — 23.4x AYTU's $63M. PAHC is the more profitable business, keeping 6.3% of every revenue dollar as net income compared to AYTU's -39.0%. On growth, SUPN holds the edge at +38.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricAYTU logoAYTUAytu BioPharma, I…ASRT logoASRTAssertio Holdings…SUPN logoSUPNSupernus Pharmace…PAHC logoPAHCPhibro Animal Hea…
RevenueTrailing 12 months$63M$119M$777M$1.5B
EBITDAEarnings before interest/tax-$4M$8M$29M$220M
Net IncomeAfter-tax profit-$24M-$30M-$29M$92M
Free Cash FlowCash after capex-$698,000-$28M$82M$47M
Gross MarginGross profit ÷ Revenue+66.0%+70.2%+89.4%+31.9%
Operating MarginEBIT ÷ Revenue-13.9%-18.1%-5.5%+11.6%
Net MarginNet income ÷ Revenue-39.0%-24.9%-3.7%+6.3%
FCF MarginFCF ÷ Revenue-1.1%-23.7%+10.6%+3.2%
Rev. Growth (YoY)Latest quarter vs prior year-6.5%-57.9%+38.6%+20.9%
EPS Growth (YoY)Latest quarter vs prior year-3.0%-12.7%+81.0%+7.4%
Evenly matched — SUPN and PAHC each lead in 3 of 6 comparable metrics.

Valuation Metrics

PAHC leads this category, winning 3 of 6 comparable metrics.

On an enterprise value basis, PAHC's 15.7x EV/EBITDA is more attractive than SUPN's 53.4x.

MetricAYTU logoAYTUAytu BioPharma, I…ASRT logoASRTAssertio Holdings…SUPN logoSUPNSupernus Pharmace…PAHC logoPAHCPhibro Animal Hea…
Market CapShares × price$16M$144M$3.0B$1.7B
Enterprise ValueMkt cap + debt − cash$7M$173M$2.9B$2.4B
Trailing P/EPrice ÷ TTM EPS-1.14x-4.72x-76.88x36.27x
Forward P/EPrice ÷ next-FY EPS est.24.12x14.23x
PEG RatioP/E ÷ EPS growth rate4.85x
EV / EBITDAEnterprise value multiple20.37x53.44x15.65x
Price / SalesMarket cap ÷ Revenue0.23x1.21x4.19x1.35x
Price / BookPrice ÷ Book value/share0.82x1.52x2.78x6.15x
Price / FCFMarket cap ÷ FCF65.45x41.82x
PAHC leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

PAHC leads this category, winning 6 of 9 comparable metrics.

PAHC delivers a 30.8% return on equity — every $100 of shareholder capital generates $31 in annual profit, vs $-172 for AYTU. SUPN carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to PAHC's 2.67x. On the Piotroski fundamental quality scale (0–9), PAHC scores 5/9 vs ASRT's 3/9, reflecting solid financial health.

MetricAYTU logoAYTUAytu BioPharma, I…ASRT logoASRTAssertio Holdings…SUPN logoSUPNSupernus Pharmace…PAHC logoPAHCPhibro Animal Hea…
ROE (TTM)Return on equity-172.1%-29.4%-2.7%+30.8%
ROA (TTM)Return on assets-20.0%-10.3%-2.0%+6.7%
ROICReturn on invested capital-33.5%-13.8%-2.8%+9.8%
ROCEReturn on capital employed-13.3%-13.9%-3.4%+12.0%
Piotroski ScoreFundamental quality 0–93345
Debt / EquityFinancial leverage1.21x0.42x0.04x2.67x
Net DebtTotal debt minus cash-$8M$29M-$87M$694M
Cash & Equiv.Liquid assets$31M$10M$128M$68M
Total DebtShort + long-term debt$23M$39M$41M$762M
Interest CoverageEBIT ÷ Interest expense-7.96x-4.45x3.64x
PAHC leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ASRT leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in ASRT five years ago would be worth $98,114 today (with dividends reinvested), compared to $215 for AYTU. Over the past 12 months, ASRT leads with a +3525.0% total return vs SUPN's +69.0%. The 3-year compound annual growth rate (CAGR) favors ASRT at 52.9% vs AYTU's 12.0% — a key indicator of consistent wealth creation.

MetricAYTU logoAYTUAytu BioPharma, I…ASRT logoASRTAssertio Holdings…SUPN logoSUPNSupernus Pharmace…PAHC logoPAHCPhibro Animal Hea…
YTD ReturnYear-to-date-10.8%+144.7%+5.7%+16.0%
1-Year ReturnPast 12 months+104.1%+3525.0%+69.0%+125.1%
3-Year ReturnCumulative with dividends+40.3%+257.3%+42.1%+210.4%
5-Year ReturnCumulative with dividends-97.8%+881.1%+78.0%+66.0%
10-Year ReturnCumulative with dividends-100.0%-68.7%+228.4%+128.6%
CAGR (3Y)Annualised 3-year return+12.0%+52.9%+12.4%+45.9%
ASRT leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

ASRT leads this category, winning 2 of 2 comparable metrics.

ASRT is the less volatile stock with a 0.72 beta — it tends to amplify market swings less than PAHC's 1.38 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ASRT currently trades 99.4% from its 52-week high vs PAHC's 71.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricAYTU logoAYTUAytu BioPharma, I…ASRT logoASRTAssertio Holdings…SUPN logoSUPNSupernus Pharmace…PAHC logoPAHCPhibro Animal Hea…
Beta (5Y)Sensitivity to S&P 5001.27x0.72x0.78x1.38x
52-Week HighHighest price in past year$3.07$22.50$59.68$60.08
52-Week LowLowest price in past year$1.20$0.58$29.16$19.00
% of 52W HighCurrent price vs 52-week peak+80.5%+99.4%+87.6%+71.8%
RSI (14)Momentum oscillator 0–10048.986.457.960.3
Avg Volume (50D)Average daily shares traded42K247K604K302K
ASRT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: ASRT as "Hold", SUPN as "Buy", PAHC as "Buy". Consensus price targets imply 14.8% upside for SUPN (target: $60) vs -19.5% for ASRT (target: $18). PAHC is the only dividend payer here at 1.11% yield — a key consideration for income-focused portfolios.

MetricAYTU logoAYTUAytu BioPharma, I…ASRT logoASRTAssertio Holdings…SUPN logoSUPNSupernus Pharmace…PAHC logoPAHCPhibro Animal Hea…
Analyst RatingConsensus buy/hold/sellHoldBuyBuy
Price TargetConsensus 12-month target$18.00$60.00$49.00
# AnalystsCovering analysts181413
Dividend YieldAnnual dividend ÷ price+1.1%
Dividend StreakConsecutive years of raises0
Dividend / ShareAnnual DPS$0.48
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

PAHC leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). ASRT leads in 2 (Total Returns, Risk & Volatility). 1 tied.

Best OverallAssertio Holdings, Inc. (ASRT)Leads 2 of 6 categories
Loading custom metrics...

AYTU vs ASRT vs SUPN vs PAHC: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is AYTU or ASRT or SUPN or PAHC a better buy right now?

For growth investors, Phibro Animal Health Corporation (PAHC) is the stronger pick with 27.

4% revenue growth year-over-year, versus -5. 0% for Assertio Holdings, Inc. (ASRT). Phibro Animal Health Corporation (PAHC) offers the better valuation at 36. 3x trailing P/E (14. 2x forward), making it the more compelling value choice. Analysts rate Supernus Pharmaceuticals, Inc. (SUPN) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — AYTU or ASRT or SUPN or PAHC?

On forward P/E, Phibro Animal Health Corporation is actually cheaper at 14.

2x.

03

Which is the better long-term investment — AYTU or ASRT or SUPN or PAHC?

Over the past 5 years, Assertio Holdings, Inc.

(ASRT) delivered a total return of +881. 1%, compared to -97. 8% for Aytu BioPharma, Inc. (AYTU). Over 10 years, the gap is even starker: SUPN returned +228. 4% versus AYTU's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — AYTU or ASRT or SUPN or PAHC?

By beta (market sensitivity over 5 years), Assertio Holdings, Inc.

(ASRT) is the lower-risk stock at 0. 72β versus Phibro Animal Health Corporation's 1. 38β — meaning PAHC is approximately 91% more volatile than ASRT relative to the S&P 500. On balance sheet safety, Supernus Pharmaceuticals, Inc. (SUPN) carries a lower debt/equity ratio of 4% versus 3% for Phibro Animal Health Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — AYTU or ASRT or SUPN or PAHC?

By revenue growth (latest reported year), Phibro Animal Health Corporation (PAHC) is pulling ahead at 27.

4% versus -5. 0% for Assertio Holdings, Inc. (ASRT). On earnings-per-share growth, the picture is similar: Phibro Animal Health Corporation grew EPS 1883% year-over-year, compared to -151. 5% for Supernus Pharmaceuticals, Inc.. Over a 3-year CAGR, PAHC leads at 11. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — AYTU or ASRT or SUPN or PAHC?

Phibro Animal Health Corporation (PAHC) is the more profitable company, earning 3.

7% net margin versus -24. 9% for Assertio Holdings, Inc. — meaning it keeps 3. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: PAHC leads at 8. 5% versus -18. 1% for ASRT. At the gross margin level — before operating expenses — SUPN leads at 89. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is AYTU or ASRT or SUPN or PAHC more undervalued right now?

On forward earnings alone, Phibro Animal Health Corporation (PAHC) trades at 14.

2x forward P/E versus 24. 1x for Supernus Pharmaceuticals, Inc. — 9. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for SUPN: 14. 8% to $60. 00.

08

Which pays a better dividend — AYTU or ASRT or SUPN or PAHC?

In this comparison, PAHC (1.

1% yield) pays a dividend. AYTU, ASRT, SUPN do not pay a meaningful dividend and should not be held primarily for income.

09

Is AYTU or ASRT or SUPN or PAHC better for a retirement portfolio?

For long-horizon retirement investors, Supernus Pharmaceuticals, Inc.

(SUPN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 78), +228. 4% 10Y return). Both have compounded well over 10 years (SUPN: +228. 4%, AYTU: -100. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between AYTU and ASRT and SUPN and PAHC?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: AYTU is a small-cap quality compounder stock; ASRT is a small-cap quality compounder stock; SUPN is a small-cap quality compounder stock; PAHC is a small-cap high-growth stock. PAHC pays a dividend while AYTU, ASRT, SUPN do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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AYTU

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 39%
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ASRT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 42%
Run This Screen
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SUPN

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 19%
  • Gross Margin > 53%
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PAHC

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 10%
  • Net Margin > 5%
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Beat Both

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Revenue Growth>
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(AYTU: -6.5% · ASRT: -57.9%)

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