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Aytu BioPharma, Inc. (AYTU) Total Return Calculator with Dividends Reinvested

Aytu BioPharma, Inc.

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The total return for Aytu BioPharma, Inc. (AYTU) stock is +104.80% over the past 12 months. So far it's down 7.58% this year. The 5-year total return is -97.82%, meaning $10,000 invested in AYTU stock 5 years ago would be worth $218 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in AYTU 1 year ago, it would be worth $21,157 today — you'd have gained $11,157.

With Dividends Reinvested$21,157+111.57%

Price Only (No DRIP)$21,157+111.57%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in AYTU

1Y$20,480+$10,480 (+104.8%)104.8% CAGR

3Y$14,545+$4,545 (+45.5%)13.3% CAGR

5Y$218-$9,782 (-97.8%)-53.5% CAGR

10Y$0-$10,000 (-100.0%)-69.1% CAGR

15Y$0-$10,000 (-100.0%)-57.2% CAGR

20Y$0-$10,000 (-100.0%)-47.1% CAGR

30Y$0-$10,000 (-100.0%)-34.6% CAGR

Aytu BioPharma, Inc. did not pay dividends during this period. Total return = price return.

Loading AYTU total return...

As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-7.58%	—	-7.58%	—	$9,242
1Y	+104.80%	104.80%	+104.80%	—	$20,480
3Y	+45.45%	13.30%	+45.45%	—	$14,545
5Y	-97.82%	-53.46%	-97.82%	—	$218
10Y	-100.00%	-69.08%	-100.00%	—	$0
15Y	-100.00%	-57.16%	-100.00%	—	$0
20Y	-100.00%	-47.05%	-100.00%	—	$0
30Y	-100.00%	-34.55%	-100.00%	—	$0

Risk & Highlights

Best Year+52.94%2025

Worst Year-98.29%2018

Max Drawdown-42.47%2025-05-15 → 2025-06-05 · Recovered 2025-07-23

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-7.22%	-7.22%	—	+0.41%	-7.6pp
2025	+52.94%	+52.94%	—	+16.64%	+36.3pp
2024	-41.18%	-41.18%	—	+24.00%	-65.2pp
2023	-29.00%	-29.00%	—	+24.81%	-53.8pp
2022	-87.74%	-87.74%	—	-19.95%	-67.8pp

AYTU outperformed the S&P 500 by 73.48pp over the past year (+104.80% vs +31.32%).

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AYTU Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
AYTUAytu BioPharma, Inc.	$16M	-3.8%	-7.6%	+104.8%	—	+45.5%	-97.8%	-100.0%
SUPNSupernus Pharmaceuticals, Inc.	$3.0B	+1.8%	+4.0%	+58.6%	—	+39.8%	+75.7%	+240.3%
TPVGTriplePoint Venture Growth BDC Corp.	$226M	+7.1%	-12.7%	+8.6%	+16.7pp	-7.5%	-19.0%	+87.8%
ASRTAssertio Holdings, Inc.	$143M	+15.3%	+142.9%	+3539.3%	—	+254.6%	+1010.0%	-64.2%
PRGOPerrigo Company plc	$1.7B	+15.8%	-9.6%	-45.6%	+4.7pp	-56.6%	-58.6%	-76.8%
COLLCollegium Pharmaceutical, Inc.	$1.2B	+12.0%	-19.8%	+35.1%	—	+55.9%	+66.4%	+141.8%
JAZZJazz Pharmaceuticals plc	$14.3B	+22.3%	+32.0%	+105.6%	—	+64.8%	+32.2%	+58.3%
NKTRNektar Therapeutics	$1.7B	+13.9%	+96.0%	+783.6%	—	+636.7%	-69.4%	-57.6%
TEVATeva Pharmaceutical Industries Limited	$42.3B	+21.8%	+17.4%	+125.4%	—	+301.0%	+253.1%	-24.0%
PAHCPhibro Animal Health Corporation	$2.4B	+6.7%	+57.5%	+210.5%	+2.5pp	+318.1%	+136.4%	+207.3%
MCKMcKesson Corporation	$91.1B	-13.2%	-9.6%	+5.0%	+0.4pp	+104.0%	+308.4%	+351.9%

Compare:AYTU vs SUPN AYTU vs TPVG AYTU vs ASRT AYTU vs SUPN vs TPVG

About AYTU Dividend Returns

Aytu BioPharma, Inc. (AYTU) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of AYTU over the past year?

Aytu BioPharma, Inc. (AYTU) delivered a return of 104.80% over the past year. Since AYTU does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in AYTU be worth today?

A $10,000 investment in Aytu BioPharma, Inc. one year ago would be worth $20,480 today, representing a gain of $10,480.

Q3Does AYTU pay dividends?

Aytu BioPharma, Inc. (AYTU) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For AYTU, the total return equals the price-only return.

Q4Did AYTU beat the S&P 500?

Yes, Aytu BioPharma, Inc. (AYTU) outperformed the S&P 500 by 73.48 percentage points over the past year. AYTU delivered a total return of 104.80%, compared to the S&P 500's 31.32%. This 73.48pp alpha means investors in AYTU earned more than a passive S&P 500 index fund.

Q5What is AYTU's worst drawdown?

Aytu BioPharma, Inc. (AYTU) experienced a maximum drawdown of -42.47% over the past year, declining from its peak on 2025-05-15 to its trough on 2025-06-05. The stock recovered to its prior peak by 2025-07-23. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is AYTU's long-term total return over 10, 20, or 30 years?

Here are Aytu BioPharma, Inc. (AYTU)'s long-term returns with dividends reinvested. Over 10 years, the total return is -100.0% (-69.1% CAGR) — $10,000 would have grown to $0. Over 20 years: -100.0% total return (-47.1% CAGR) — $10,000 → $0. Over 30 years: -100.0% total return (-34.6% CAGR) — $10,000 → $0. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was AYTU's best and worst year?

Aytu BioPharma, Inc.'s best calendar year was 2025 with a total return of 52.9%. Its worst year was 2018 with a total return of -98.3%. This range shows the volatility investors should expect — the difference between the best and worst year is 151.2 percentage points.