Biotechnology
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5 / 10Stock Comparison
CLRB vs PRTC vs RNAC vs RMD vs NUVL
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Instruments & Supplies
Biotechnology
CLRB vs PRTC vs RNAC vs RMD vs NUVL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Medical - Instruments & Supplies | Biotechnology |
| Market Cap | $14M | $41M | $216M | $30.15B | $7.53B |
| Revenue (TTM) | $0.00 | $9M | $2M | $5.54B | $0.00 |
| Net Income (TTM) | $-22M | $-56M | $-152M | $1.52B | $-450M |
| Gross Margin | — | -196.2% | -6.3% | 61.7% | — |
| Operating Margin | — | -26.2% | -51.4% | 34.3% | — |
| Forward P/E | — | — | — | 18.8x | — |
| Total Debt | $410K | $20M | $13M | $852M | $0.00 |
| Cash & Equiv. | $13M | $254M | $125M | $1.21B | $262M |
CLRB vs PRTC vs RNAC vs RMD vs NUVL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jul 21 | May 26 | Return |
|---|---|---|---|
| Cellectar Bioscienc… (CLRB) | 100 | 1.0 | -99.0% |
| PureTech Health plc (PRTC) | 100 | 35.6 | -64.4% |
| Cartesian Therapeut… (RNAC) | 100 | 7.9 | -92.1% |
| ResMed Inc. (RMD) | 100 | 76.1 | -23.9% |
| Nuvalent, Inc. (NUVL) | 100 | 561.1 | +461.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CLRB vs PRTC vs RNAC vs RMD vs NUVL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CLRB is the #2 pick in this set and the best alternative if growth is your priority.
- 51.3% revenue growth vs RNAC's -92.8%
PRTC ranks third and is worth considering specifically for sleep-well-at-night and defensive.
- Lower volatility, beta 0.51, Low D/E 6.5%, current ratio 6.59x
- Beta 0.51, current ratio 6.59x
- Beta 0.51 vs RNAC's 2.03
Among these 5 stocks, RNAC doesn't own a clear edge in any measured category.
RMD carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 14 yrs, beta 0.66, yield 1.0%
- Rev growth 9.8%, EPS growth 37.4%, 3Y rev CAGR 12.9%
- 27.4% margin vs RNAC's -85.5%
- 1.0% yield; 14-year raise streak; the other 4 pay no meaningful dividend
NUVL is the clearest fit if your priority is long-term compounding.
- 446.1% 10Y total return vs RMD's 293.8%
- +53.5% vs CLRB's -55.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 51.3% revenue growth vs RNAC's -92.8% | |
| Quality / Margins | 27.4% margin vs RNAC's -85.5% | |
| Stability / Safety | Beta 0.51 vs RNAC's 2.03 | |
| Dividends | 1.0% yield; 14-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +53.5% vs CLRB's -55.0% | |
| Efficiency (ROA) | 18.0% ROA vs CLRB's -146.9% |
CLRB vs PRTC vs RNAC vs RMD vs NUVL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
CLRB vs PRTC vs RNAC vs RMD vs NUVL — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
RMD leads in 3 of 6 categories
NUVL leads 1 • CLRB leads 0 • PRTC leads 0 • RNAC leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
RMD leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RMD and NUVL operate at a comparable scale, with $5.5B and $0 in trailing revenue. RMD is the more profitable business, keeping 27.4% of every revenue dollar as net income compared to RNAC's -85.5%. On growth, RMD holds the edge at +10.8% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $9M | $2M | $5.5B | $0 |
| EBITDAEarnings before interest/tax | -$23M | -$228M | -$90M | $2.1B | -$346M |
| Net IncomeAfter-tax profit | -$22M | -$56M | -$152M | $1.5B | -$450M |
| Free Cash FlowCash after capex | -$23M | -$219M | -$77M | $1.8B | -$313M |
| Gross MarginGross profit ÷ Revenue | — | -196.2% | -6.3% | +61.7% | — |
| Operating MarginEBIT ÷ Revenue | — | -26.2% | -51.4% | +34.3% | — |
| Net MarginNet income ÷ Revenue | — | -6.2% | -85.5% | +27.4% | — |
| FCF MarginFCF ÷ Revenue | — | -24.4% | -43.6% | +31.7% | — |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -30.5% | -92.9% | +10.8% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +25.6% | -8.7% | -114.7% | +9.3% | -17.8% |
Valuation Metrics
Evenly matched — PRTC and RMD and NUVL each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $14M | $41M | $216M | $30.1B | $7.5B |
| Enterprise ValueMkt cap + debt − cash | $1M | -$193M | $104M | $29.8B | $7.3B |
| Trailing P/EPrice ÷ TTM EPS | -0.40x | -0.37x | -1.63x | 21.76x | -17.50x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 18.78x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 1.25x | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 15.51x | — |
| Price / SalesMarket cap ÷ Revenue | — | 8.79x | 77.34x | 5.86x | — |
| Price / BookPrice ÷ Book value/share | 0.87x | 0.13x | — | 5.11x | 5.96x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 18.14x | — |
Profitability & Efficiency
RMD leads this category, winning 7 of 9 comparable metrics.
Profitability & Efficiency
RMD delivers a 24.4% return on equity — every $100 of shareholder capital generates $24 in annual profit, vs $-2 for CLRB. CLRB carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to RMD's 0.14x. On the Piotroski fundamental quality scale (0–9), RMD scores 8/9 vs NUVL's 1/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -2.5% | -16.1% | — | +24.4% | -42.8% |
| ROA (TTM)Return on assets | -146.9% | -9.9% | -45.1% | +18.0% | -37.8% |
| ROICReturn on invested capital | — | -66.9% | — | +22.8% | -32.5% |
| ROCEReturn on capital employed | -174.7% | -18.8% | -25.0% | +25.7% | -34.4% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 5 | 1 | 8 | 1 |
| Debt / EquityFinancial leverage | 0.04x | 0.06x | — | 0.14x | — |
| Net DebtTotal debt minus cash | -$13M | -$234M | -$112M | -$358M | -$262M |
| Cash & Equiv.Liquid assets | $13M | $254M | $125M | $1.2B | $262M |
| Total DebtShort + long-term debt | $409,586 | $20M | $13M | $852M | $0 |
| Interest CoverageEBIT ÷ Interest expense | — | -1.16x | — | 66.06x | -26.85x |
Total Returns (Dividends Reinvested)
NUVL leads this category, winning 5 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in NUVL five years ago would be worth $54,613 today (with dividends reinvested), compared to $81 for CLRB. Over the past 12 months, NUVL leads with a +53.5% total return vs CLRB's -55.0%. The 3-year compound annual growth rate (CAGR) favors NUVL at 39.5% vs CLRB's -57.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -4.9% | +2.0% | +20.7% | -15.2% | +1.5% |
| 1-Year ReturnPast 12 months | -55.0% | -2.6% | -19.6% | -14.5% | +53.5% |
| 3-Year ReturnCumulative with dividends | -92.4% | -41.3% | -77.1% | -8.4% | +171.2% |
| 5-Year ReturnCumulative with dividends | -99.2% | -70.1% | -91.3% | +11.0% | +446.1% |
| 10-Year ReturnCumulative with dividends | -99.9% | -55.9% | -98.1% | +293.8% | +446.1% |
| CAGR (3Y)Annualised 3-year return | -57.7% | -16.3% | -38.9% | -2.9% | +39.5% |
Risk & Volatility
Evenly matched — PRTC and NUVL each lead in 1 of 2 comparable metrics.
Risk & Volatility
PRTC is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than RNAC's 2.03 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NUVL currently trades 90.6% from its 52-week high vs CLRB's 16.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.76x | 0.51x | 2.03x | 0.66x | 1.09x |
| 52-Week HighHighest price in past year | $20.59 | $19.92 | $15.57 | $293.81 | $113.02 |
| 52-Week LowLowest price in past year | $2.43 | $14.50 | $5.60 | $198.64 | $63.56 |
| % of 52W HighCurrent price vs 52-week peak | +16.0% | +85.2% | +52.4% | +70.4% | +90.6% |
| RSI (14)Momentum oscillator 0–100 | 71.7 | 48.2 | 68.7 | 35.6 | 52.9 |
| Avg Volume (50D)Average daily shares traded | 1.2M | 8K | 225K | 1.1M | 544K |
Analyst Outlook
RMD leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: PRTC as "Buy", RNAC as "Buy", RMD as "Buy", NUVL as "Buy". Consensus price targets imply 235.9% upside for PRTC (target: $57) vs 35.9% for RMD (target: $281). RMD is the only dividend payer here at 1.02% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $57.00 | $16.00 | $281.29 | $144.40 |
| # AnalystsCovering analysts | — | 2 | 10 | 35 | 14 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +1.0% | — |
| Dividend StreakConsecutive years of raises | — | 1 | — | 14 | — |
| Dividend / ShareAnnual DPS | — | — | — | $2.11 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +5.0% | 0.0% | +1.0% | 0.0% |
RMD leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NUVL leads in 1 (Total Returns). 2 tied.
CLRB vs PRTC vs RNAC vs RMD vs NUVL: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is CLRB or PRTC or RNAC or RMD or NUVL a better buy right now?
For growth investors, ResMed Inc.
(RMD) is the stronger pick with 9. 8% revenue growth year-over-year, versus -92. 8% for Cartesian Therapeutics, Inc. (RNAC). ResMed Inc. (RMD) offers the better valuation at 21. 8x trailing P/E (18. 8x forward), making it the more compelling value choice. Analysts rate PureTech Health plc (PRTC) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CLRB or PRTC or RNAC or RMD or NUVL?
Over the past 5 years, Nuvalent, Inc.
(NUVL) delivered a total return of +446. 1%, compared to -99. 2% for Cellectar Biosciences, Inc. (CLRB). Over 10 years, the gap is even starker: NUVL returned +446. 1% versus CLRB's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CLRB or PRTC or RNAC or RMD or NUVL?
By beta (market sensitivity over 5 years), PureTech Health plc (PRTC) is the lower-risk stock at 0.
51β versus Cartesian Therapeutics, Inc. 's 2. 03β — meaning RNAC is approximately 299% more volatile than PRTC relative to the S&P 500. On balance sheet safety, Cellectar Biosciences, Inc. (CLRB) carries a lower debt/equity ratio of 4% versus 14% for ResMed Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CLRB or PRTC or RNAC or RMD or NUVL?
By revenue growth (latest reported year), ResMed Inc.
(RMD) is pulling ahead at 9. 8% versus -92. 8% for Cartesian Therapeutics, Inc. (RNAC). On earnings-per-share growth, the picture is similar: Cellectar Biosciences, Inc. grew EPS 80. 1% year-over-year, compared to -24. 0% for PureTech Health plc. Over a 3-year CAGR, PRTC leads at 30. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CLRB or PRTC or RNAC or RMD or NUVL?
ResMed Inc.
(RMD) is the more profitable company, earning 27. 2% net margin versus -46. 6% for Cartesian Therapeutics, Inc. — meaning it keeps 27. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RMD leads at 32. 7% versus -31. 0% for RNAC. At the gross margin level — before operating expenses — PRTC leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is CLRB or PRTC or RNAC or RMD or NUVL more undervalued right now?
Analyst consensus price targets imply the most upside for PRTC: 235.
9% to $57. 00.
07Which pays a better dividend — CLRB or PRTC or RNAC or RMD or NUVL?
In this comparison, RMD (1.
0% yield) pays a dividend. CLRB, PRTC, RNAC, NUVL do not pay a meaningful dividend and should not be held primarily for income.
08Is CLRB or PRTC or RNAC or RMD or NUVL better for a retirement portfolio?
For long-horizon retirement investors, ResMed Inc.
(RMD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 66), 1. 0% yield, +293. 8% 10Y return). Cartesian Therapeutics, Inc. (RNAC) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RMD: +293. 8%, RNAC: -98. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between CLRB and PRTC and RNAC and RMD and NUVL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
RMD pays a dividend while CLRB, PRTC, RNAC, NUVL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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