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CLRB vs PRTC vs RNAC vs RMD vs NUVL

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CLRB
Cellectar Biosciences, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$14M
5Y Perf.-99.0%
PRTC
PureTech Health plc

Biotechnology

HealthcareNASDAQ • US
Market Cap$41M
5Y Perf.-64.4%
RNAC
Cartesian Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$216M
5Y Perf.-92.1%
RMD
ResMed Inc.

Medical - Instruments & Supplies

HealthcareNYSE • US
Market Cap$30.15B
5Y Perf.-23.9%
NUVL
Nuvalent, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.53B
5Y Perf.+461.1%

CLRB vs PRTC vs RNAC vs RMD vs NUVL — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CLRB logoCLRB
PRTC logoPRTC
RNAC logoRNAC
RMD logoRMD
NUVL logoNUVL
IndustryBiotechnologyBiotechnologyBiotechnologyMedical - Instruments & SuppliesBiotechnology
Market Cap$14M$41M$216M$30.15B$7.53B
Revenue (TTM)$0.00$9M$2M$5.54B$0.00
Net Income (TTM)$-22M$-56M$-152M$1.52B$-450M
Gross Margin-196.2%-6.3%61.7%
Operating Margin-26.2%-51.4%34.3%
Forward P/E18.8x
Total Debt$410K$20M$13M$852M$0.00
Cash & Equiv.$13M$254M$125M$1.21B$262M

CLRB vs PRTC vs RNAC vs RMD vs NUVLLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CLRB
PRTC
RNAC
RMD
NUVL
StockJul 21May 26Return
Cellectar Bioscienc… (CLRB)1001.0-99.0%
PureTech Health plc (PRTC)10035.6-64.4%
Cartesian Therapeut… (RNAC)1007.9-92.1%
ResMed Inc. (RMD)10076.1-23.9%
Nuvalent, Inc. (NUVL)100561.1+461.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: CLRB vs PRTC vs RNAC vs RMD vs NUVL

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: RMD leads in 3 of 6 categories (5-stock set), making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Cellectar Biosciences, Inc. is the stronger pick specifically for growth and revenue expansion. PRTC and NUVL also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
CLRB
Cellectar Biosciences, Inc.
The Growth Leader

CLRB is the #2 pick in this set and the best alternative if growth is your priority.

  • 51.3% revenue growth vs RNAC's -92.8%
Best for: growth
PRTC
PureTech Health plc
The Defensive Pick

PRTC ranks third and is worth considering specifically for sleep-well-at-night and defensive.

  • Lower volatility, beta 0.51, Low D/E 6.5%, current ratio 6.59x
  • Beta 0.51, current ratio 6.59x
  • Beta 0.51 vs RNAC's 2.03
Best for: sleep-well-at-night and defensive
RNAC
Cartesian Therapeutics, Inc.
The Healthcare Pick

Among these 5 stocks, RNAC doesn't own a clear edge in any measured category.

Best for: healthcare exposure
RMD
ResMed Inc.
The Income Pick

RMD carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 14 yrs, beta 0.66, yield 1.0%
  • Rev growth 9.8%, EPS growth 37.4%, 3Y rev CAGR 12.9%
  • 27.4% margin vs RNAC's -85.5%
  • 1.0% yield; 14-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability and growth exposure
NUVL
Nuvalent, Inc.
The Long-Run Compounder

NUVL is the clearest fit if your priority is long-term compounding.

  • 446.1% 10Y total return vs RMD's 293.8%
  • +53.5% vs CLRB's -55.0%
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthCLRB logoCLRB51.3% revenue growth vs RNAC's -92.8%
Quality / MarginsRMD logoRMD27.4% margin vs RNAC's -85.5%
Stability / SafetyPRTC logoPRTCBeta 0.51 vs RNAC's 2.03
DividendsRMD logoRMD1.0% yield; 14-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)NUVL logoNUVL+53.5% vs CLRB's -55.0%
Efficiency (ROA)RMD logoRMD18.0% ROA vs CLRB's -146.9%

CLRB vs PRTC vs RNAC vs RMD vs NUVL — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CLRBCellectar Biosciences, Inc.

Segment breakdown not available.

PRTCPureTech Health plc

Segment breakdown not available.

RNACCartesian Therapeutics, Inc.
FY 2025
Operating Segment
100.0%$3M
RMDResMed Inc.
FY 2024
Sleep And Respiratory
87.5%$4.1B
Software As Service
12.5%$584M
NUVLNuvalent, Inc.

Segment breakdown not available.

CLRB vs PRTC vs RNAC vs RMD vs NUVL — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLRMDLAGGINGRNAC

Income & Cash Flow (Last 12 Months)

RMD leads this category, winning 5 of 6 comparable metrics.

RMD and NUVL operate at a comparable scale, with $5.5B and $0 in trailing revenue. RMD is the more profitable business, keeping 27.4% of every revenue dollar as net income compared to RNAC's -85.5%. On growth, RMD holds the edge at +10.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCLRB logoCLRBCellectar Bioscie…PRTC logoPRTCPureTech Health p…RNAC logoRNACCartesian Therape…RMD logoRMDResMed Inc.NUVL logoNUVLNuvalent, Inc.
RevenueTrailing 12 months$0$9M$2M$5.5B$0
EBITDAEarnings before interest/tax-$23M-$228M-$90M$2.1B-$346M
Net IncomeAfter-tax profit-$22M-$56M-$152M$1.5B-$450M
Free Cash FlowCash after capex-$23M-$219M-$77M$1.8B-$313M
Gross MarginGross profit ÷ Revenue-196.2%-6.3%+61.7%
Operating MarginEBIT ÷ Revenue-26.2%-51.4%+34.3%
Net MarginNet income ÷ Revenue-6.2%-85.5%+27.4%
FCF MarginFCF ÷ Revenue-24.4%-43.6%+31.7%
Rev. Growth (YoY)Latest quarter vs prior year-30.5%-92.9%+10.8%
EPS Growth (YoY)Latest quarter vs prior year+25.6%-8.7%-114.7%+9.3%-17.8%
RMD leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

Evenly matched — PRTC and RMD and NUVL each lead in 1 of 3 comparable metrics.
MetricCLRB logoCLRBCellectar Bioscie…PRTC logoPRTCPureTech Health p…RNAC logoRNACCartesian Therape…RMD logoRMDResMed Inc.NUVL logoNUVLNuvalent, Inc.
Market CapShares × price$14M$41M$216M$30.1B$7.5B
Enterprise ValueMkt cap + debt − cash$1M-$193M$104M$29.8B$7.3B
Trailing P/EPrice ÷ TTM EPS-0.40x-0.37x-1.63x21.76x-17.50x
Forward P/EPrice ÷ next-FY EPS est.18.78x
PEG RatioP/E ÷ EPS growth rate1.25x
EV / EBITDAEnterprise value multiple15.51x
Price / SalesMarket cap ÷ Revenue8.79x77.34x5.86x
Price / BookPrice ÷ Book value/share0.87x0.13x5.11x5.96x
Price / FCFMarket cap ÷ FCF18.14x
Evenly matched — PRTC and RMD and NUVL each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

RMD leads this category, winning 7 of 9 comparable metrics.

RMD delivers a 24.4% return on equity — every $100 of shareholder capital generates $24 in annual profit, vs $-2 for CLRB. CLRB carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to RMD's 0.14x. On the Piotroski fundamental quality scale (0–9), RMD scores 8/9 vs NUVL's 1/9, reflecting strong financial health.

MetricCLRB logoCLRBCellectar Bioscie…PRTC logoPRTCPureTech Health p…RNAC logoRNACCartesian Therape…RMD logoRMDResMed Inc.NUVL logoNUVLNuvalent, Inc.
ROE (TTM)Return on equity-2.5%-16.1%+24.4%-42.8%
ROA (TTM)Return on assets-146.9%-9.9%-45.1%+18.0%-37.8%
ROICReturn on invested capital-66.9%+22.8%-32.5%
ROCEReturn on capital employed-174.7%-18.8%-25.0%+25.7%-34.4%
Piotroski ScoreFundamental quality 0–925181
Debt / EquityFinancial leverage0.04x0.06x0.14x
Net DebtTotal debt minus cash-$13M-$234M-$112M-$358M-$262M
Cash & Equiv.Liquid assets$13M$254M$125M$1.2B$262M
Total DebtShort + long-term debt$409,586$20M$13M$852M$0
Interest CoverageEBIT ÷ Interest expense-1.16x66.06x-26.85x
RMD leads this category, winning 7 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NUVL leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in NUVL five years ago would be worth $54,613 today (with dividends reinvested), compared to $81 for CLRB. Over the past 12 months, NUVL leads with a +53.5% total return vs CLRB's -55.0%. The 3-year compound annual growth rate (CAGR) favors NUVL at 39.5% vs CLRB's -57.7% — a key indicator of consistent wealth creation.

MetricCLRB logoCLRBCellectar Bioscie…PRTC logoPRTCPureTech Health p…RNAC logoRNACCartesian Therape…RMD logoRMDResMed Inc.NUVL logoNUVLNuvalent, Inc.
YTD ReturnYear-to-date-4.9%+2.0%+20.7%-15.2%+1.5%
1-Year ReturnPast 12 months-55.0%-2.6%-19.6%-14.5%+53.5%
3-Year ReturnCumulative with dividends-92.4%-41.3%-77.1%-8.4%+171.2%
5-Year ReturnCumulative with dividends-99.2%-70.1%-91.3%+11.0%+446.1%
10-Year ReturnCumulative with dividends-99.9%-55.9%-98.1%+293.8%+446.1%
CAGR (3Y)Annualised 3-year return-57.7%-16.3%-38.9%-2.9%+39.5%
NUVL leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — PRTC and NUVL each lead in 1 of 2 comparable metrics.

PRTC is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than RNAC's 2.03 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. NUVL currently trades 90.6% from its 52-week high vs CLRB's 16.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCLRB logoCLRBCellectar Bioscie…PRTC logoPRTCPureTech Health p…RNAC logoRNACCartesian Therape…RMD logoRMDResMed Inc.NUVL logoNUVLNuvalent, Inc.
Beta (5Y)Sensitivity to S&P 5001.76x0.51x2.03x0.66x1.09x
52-Week HighHighest price in past year$20.59$19.92$15.57$293.81$113.02
52-Week LowLowest price in past year$2.43$14.50$5.60$198.64$63.56
% of 52W HighCurrent price vs 52-week peak+16.0%+85.2%+52.4%+70.4%+90.6%
RSI (14)Momentum oscillator 0–10071.748.268.735.652.9
Avg Volume (50D)Average daily shares traded1.2M8K225K1.1M544K
Evenly matched — PRTC and NUVL each lead in 1 of 2 comparable metrics.

Analyst Outlook

RMD leads this category, winning 1 of 1 comparable metric.

Analyst consensus: PRTC as "Buy", RNAC as "Buy", RMD as "Buy", NUVL as "Buy". Consensus price targets imply 235.9% upside for PRTC (target: $57) vs 35.9% for RMD (target: $281). RMD is the only dividend payer here at 1.02% yield — a key consideration for income-focused portfolios.

MetricCLRB logoCLRBCellectar Bioscie…PRTC logoPRTCPureTech Health p…RNAC logoRNACCartesian Therape…RMD logoRMDResMed Inc.NUVL logoNUVLNuvalent, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$57.00$16.00$281.29$144.40
# AnalystsCovering analysts2103514
Dividend YieldAnnual dividend ÷ price+1.0%
Dividend StreakConsecutive years of raises114
Dividend / ShareAnnual DPS$2.11
Buyback YieldShare repurchases ÷ mkt cap0.0%+5.0%0.0%+1.0%0.0%
RMD leads this category, winning 1 of 1 comparable metric.
Key Takeaway

RMD leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NUVL leads in 1 (Total Returns). 2 tied.

Best OverallResMed Inc. (RMD)Leads 3 of 6 categories
Loading custom metrics...

CLRB vs PRTC vs RNAC vs RMD vs NUVL: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is CLRB or PRTC or RNAC or RMD or NUVL a better buy right now?

For growth investors, ResMed Inc.

(RMD) is the stronger pick with 9. 8% revenue growth year-over-year, versus -92. 8% for Cartesian Therapeutics, Inc. (RNAC). ResMed Inc. (RMD) offers the better valuation at 21. 8x trailing P/E (18. 8x forward), making it the more compelling value choice. Analysts rate PureTech Health plc (PRTC) a "Buy" — based on 2 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CLRB or PRTC or RNAC or RMD or NUVL?

Over the past 5 years, Nuvalent, Inc.

(NUVL) delivered a total return of +446. 1%, compared to -99. 2% for Cellectar Biosciences, Inc. (CLRB). Over 10 years, the gap is even starker: NUVL returned +446. 1% versus CLRB's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CLRB or PRTC or RNAC or RMD or NUVL?

By beta (market sensitivity over 5 years), PureTech Health plc (PRTC) is the lower-risk stock at 0.

51β versus Cartesian Therapeutics, Inc. 's 2. 03β — meaning RNAC is approximately 299% more volatile than PRTC relative to the S&P 500. On balance sheet safety, Cellectar Biosciences, Inc. (CLRB) carries a lower debt/equity ratio of 4% versus 14% for ResMed Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — CLRB or PRTC or RNAC or RMD or NUVL?

By revenue growth (latest reported year), ResMed Inc.

(RMD) is pulling ahead at 9. 8% versus -92. 8% for Cartesian Therapeutics, Inc. (RNAC). On earnings-per-share growth, the picture is similar: Cellectar Biosciences, Inc. grew EPS 80. 1% year-over-year, compared to -24. 0% for PureTech Health plc. Over a 3-year CAGR, PRTC leads at 30. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CLRB or PRTC or RNAC or RMD or NUVL?

ResMed Inc.

(RMD) is the more profitable company, earning 27. 2% net margin versus -46. 6% for Cartesian Therapeutics, Inc. — meaning it keeps 27. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: RMD leads at 32. 7% versus -31. 0% for RNAC. At the gross margin level — before operating expenses — PRTC leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is CLRB or PRTC or RNAC or RMD or NUVL more undervalued right now?

Analyst consensus price targets imply the most upside for PRTC: 235.

9% to $57. 00.

07

Which pays a better dividend — CLRB or PRTC or RNAC or RMD or NUVL?

In this comparison, RMD (1.

0% yield) pays a dividend. CLRB, PRTC, RNAC, NUVL do not pay a meaningful dividend and should not be held primarily for income.

08

Is CLRB or PRTC or RNAC or RMD or NUVL better for a retirement portfolio?

For long-horizon retirement investors, ResMed Inc.

(RMD) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 66), 1. 0% yield, +293. 8% 10Y return). Cartesian Therapeutics, Inc. (RNAC) carries a higher beta of 2. 03 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (RMD: +293. 8%, RNAC: -98. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between CLRB and PRTC and RNAC and RMD and NUVL?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

RMD pays a dividend while CLRB, PRTC, RNAC, NUVL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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