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CVKD vs TCRX vs IMVT vs AGEN vs RCUS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CVKD
Cadrenal Therapeutics, Inc. Common Stock

Biotechnology

HealthcareNASDAQ • US
Market Cap$15M
5Y Perf.-85.6%
TCRX
TScan Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$157M
5Y Perf.-33.5%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+53.2%
AGEN
Agenus Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$132M
5Y Perf.-92.8%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.50B
5Y Perf.+14.6%

CVKD vs TCRX vs IMVT vs AGEN vs RCUS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CVKD logoCVKD
TCRX logoTCRX
IMVT logoIMVT
AGEN logoAGEN
RCUS logoRCUS
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$15M$157M$5.53B$132M$2.50B
Revenue (TTM)$0.00$8M$0.00$114M$236M
Net Income (TTM)$-9M$-124M$-464M$115K$-369M
Gross Margin81.7%35.7%90.7%
Operating Margin-15.8%-17.7%-168.6%
Forward P/E1.8x
Total Debt$0.00$94M$98K$10M$99M
Cash & Equiv.$4M$152M$714M$3M$222M

CVKD vs TCRX vs IMVT vs AGEN vs RCUSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CVKD
TCRX
IMVT
AGEN
RCUS
StockJan 23May 26Return
Cadrenal Therapeuti… (CVKD)10014.4-85.6%
TScan Therapeutics,… (TCRX)10066.5-33.5%
Immunovant, Inc. (IMVT)100153.2+53.2%
Agenus Inc. (AGEN)1007.2-92.8%
Arcus Biosciences, … (RCUS)100114.6+14.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: CVKD vs TCRX vs IMVT vs AGEN vs RCUS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: CVKD and TCRX are tied at the top with 1 category each (5-stock set) — the right choice depends on your priorities. TScan Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion. IMVT, AGEN, and RCUS also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
CVKD
Cadrenal Therapeutics, Inc. Common Stock
The Quality Compounder

CVKD has the current edge in this matchup, primarily because of its strength in quality.

  • 5.2% margin vs TCRX's -15.2%
Best for: quality
TCRX
TScan Therapeutics, Inc.
The Growth Leader

TCRX is the #2 pick in this set and the best alternative if growth is your priority.

  • 266.7% revenue growth vs CVKD's -52.9%
Best for: growth
IMVT
Immunovant, Inc.
The Income Pick

IMVT ranks third and is worth considering specifically for income & stability and long-term compounding.

  • beta 1.37
  • 173.6% 10Y total return vs RCUS's 45.9%
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.37, current ratio 11.16x
Best for: income & stability and long-term compounding
AGEN
Agenus Inc.
The Growth Play

AGEN is the clearest fit if your priority is growth exposure.

  • Rev growth 10.4%, EPS growth 100.0%, 3Y rev CAGR 5.2%
  • 0.1% ROA vs CVKD's -217.7%
Best for: growth exposure
RCUS
Arcus Biosciences, Inc.
The Momentum Pick

RCUS is the clearest fit if your priority is momentum.

  • +209.6% vs CVKD's -63.0%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthTCRX logoTCRX266.7% revenue growth vs CVKD's -52.9%
Quality / MarginsCVKD logoCVKD5.2% margin vs TCRX's -15.2%
Stability / SafetyIMVT logoIMVTBeta 1.37 vs AGEN's 2.72
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)RCUS logoRCUS+209.6% vs CVKD's -63.0%
Efficiency (ROA)AGEN logoAGEN0.1% ROA vs CVKD's -217.7%

CVKD vs TCRX vs IMVT vs AGEN vs RCUS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CVKDCadrenal Therapeutics, Inc. Common Stock

Segment breakdown not available.

TCRXTScan Therapeutics, Inc.
FY 2025
Reportable Segment
100.0%$10M
IMVTImmunovant, Inc.

Segment breakdown not available.

AGENAgenus Inc.
FY 2025
Non Cash Royalty Revenue
99.1%$109M
Other
0.9%$1M
RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M

CVKD vs TCRX vs IMVT vs AGEN vs RCUS — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLIMVTLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

AGEN leads this category, winning 5 of 6 comparable metrics.

RCUS and IMVT operate at a comparable scale, with $236M and $0 in trailing revenue. AGEN is the more profitable business, keeping 0.1% of every revenue dollar as net income compared to TCRX's -15.2%. On growth, AGEN holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCVKD logoCVKDCadrenal Therapeu…TCRX logoTCRXTScan Therapeutic…IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
RevenueTrailing 12 months$0$8M$0$114M$236M
EBITDAEarnings before interest/tax-$12M-$127M-$487M-$10M-$391M
Net IncomeAfter-tax profit-$9M-$124M-$464M$115,000-$369M
Free Cash FlowCash after capex-$11M-$125M-$423M-$159M-$489M
Gross MarginGross profit ÷ Revenue+81.7%+35.7%+90.7%
Operating MarginEBIT ÷ Revenue-15.8%-17.7%-168.6%
Net MarginNet income ÷ Revenue-15.2%+0.1%-156.4%
FCF MarginFCF ÷ Revenue-15.3%-139.1%-2.1%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%+27.5%-39.3%
EPS Growth (YoY)Latest quarter vs prior year+50.2%+15.4%+19.7%+85.3%+10.5%
AGEN leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

AGEN leads this category, winning 2 of 3 comparable metrics.
MetricCVKD logoCVKDCadrenal Therapeu…TCRX logoTCRXTScan Therapeutic…IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
Market CapShares × price$15M$157M$5.5B$132M$2.5B
Enterprise ValueMkt cap + debt − cash$11M$99M$4.8B$140M$2.4B
Trailing P/EPrice ÷ TTM EPS-0.91x-1.21x-9.97x-1102.94x-7.54x
Forward P/EPrice ÷ next-FY EPS est.1.79x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue15.22x1.16x10.11x
Price / BookPrice ÷ Book value/share4.38x1.28x5.83x4.22x
Price / FCFMarket cap ÷ FCF
AGEN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

Evenly matched — IMVT and AGEN each lead in 3 of 9 comparable metrics.

IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-3 for CVKD. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to TCRX's 0.76x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs RCUS's 0/9, reflecting solid financial health.

MetricCVKD logoCVKDCadrenal Therapeu…TCRX logoTCRXTScan Therapeutic…IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
ROE (TTM)Return on equity-3.2%-91.9%-47.1%-69.0%
ROA (TTM)Return on assets-2.2%-50.1%-44.1%+0.1%-35.3%
ROICReturn on invested capital-90.7%-64.1%
ROCEReturn on capital employed-2.6%-49.8%-66.1%-42.1%
Piotroski ScoreFundamental quality 0–912260
Debt / EquityFinancial leverage0.76x0.00x0.16x
Net DebtTotal debt minus cash-$4M-$58M-$714M$7M-$123M
Cash & Equiv.Liquid assets$4M$152M$714M$3M$222M
Total DebtShort + long-term debt$0$94M$98,000$10M$99M
Interest CoverageEBIT ÷ Interest expense-73.07x1.11x-13.38x
Evenly matched — IMVT and AGEN each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $611 for AGEN. Over the past 12 months, RCUS leads with a +209.6% total return vs CVKD's -63.0%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs AGEN's -51.0% — a key indicator of consistent wealth creation.

MetricCVKD logoCVKDCadrenal Therapeu…TCRX logoTCRXTScan Therapeutic…IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
YTD ReturnYear-to-date-17.9%+18.6%+5.1%+16.1%+6.5%
1-Year ReturnPast 12 months-63.0%-11.0%+96.1%+27.1%+209.6%
3-Year ReturnCumulative with dividends-71.7%-46.2%+40.9%-88.2%+24.9%
5-Year ReturnCumulative with dividends-90.3%-88.5%+62.4%-93.9%-18.6%
10-Year ReturnCumulative with dividends-90.3%-88.5%+173.6%-94.3%+45.9%
CAGR (3Y)Annualised 3-year return-34.4%-18.7%+12.1%-51.0%+7.7%
IMVT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

IMVT leads this category, winning 2 of 2 comparable metrics.

IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs CVKD's 36.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCVKD logoCVKDCadrenal Therapeu…TCRX logoTCRXTScan Therapeutic…IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
Beta (5Y)Sensitivity to S&P 5002.12x2.35x1.37x2.72x1.95x
52-Week HighHighest price in past year$16.50$2.57$30.09$7.34$28.72
52-Week LowLowest price in past year$4.20$0.88$13.36$2.71$7.06
% of 52W HighCurrent price vs 52-week peak+36.5%+47.1%+90.5%+51.1%+86.3%
RSI (14)Momentum oscillator 0–10054.756.860.248.860.5
Avg Volume (50D)Average daily shares traded53K910K1.4M814K1.2M
IMVT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: TCRX as "Buy", IMVT as "Buy", AGEN as "Buy", RCUS as "Buy". Consensus price targets imply 519.8% upside for TCRX (target: $8) vs 21.0% for RCUS (target: $30).

MetricCVKD logoCVKDCadrenal Therapeu…TCRX logoTCRXTScan Therapeutic…IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$7.50$45.50$7.33$30.00
# AnalystsCovering analysts8231118
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap+1.9%0.0%0.0%+0.1%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

AGEN leads in 2 of 6 categories (Income & Cash Flow, Valuation Metrics). IMVT leads in 2 (Total Returns, Risk & Volatility). 1 tied.

Best OverallImmunovant, Inc. (IMVT)Leads 2 of 6 categories
Loading custom metrics...

CVKD vs TCRX vs IMVT vs AGEN vs RCUS: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is CVKD or TCRX or IMVT or AGEN or RCUS a better buy right now?

For growth investors, TScan Therapeutics, Inc.

(TCRX) is the stronger pick with 266. 7% revenue growth year-over-year, versus -4. 3% for Arcus Biosciences, Inc. (RCUS). Analysts rate TScan Therapeutics, Inc. (TCRX) a "Buy" — based on 8 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CVKD or TCRX or IMVT or AGEN or RCUS?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +62. 4%, compared to -93. 9% for Agenus Inc. (AGEN). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus AGEN's -94. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CVKD or TCRX or IMVT or AGEN or RCUS?

By beta (market sensitivity over 5 years), Immunovant, Inc.

(IMVT) is the lower-risk stock at 1. 37β versus Agenus Inc. 's 2. 72β — meaning AGEN is approximately 98% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 76% for TScan Therapeutics, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — CVKD or TCRX or IMVT or AGEN or RCUS?

By revenue growth (latest reported year), TScan Therapeutics, Inc.

(TCRX) is pulling ahead at 266. 7% versus -4. 3% for Arcus Biosciences, Inc. (RCUS). On earnings-per-share growth, the picture is similar: Agenus Inc. grew EPS 100. 0% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CVKD or TCRX or IMVT or AGEN or RCUS?

Agenus Inc.

(AGEN) is the more profitable company, earning 0. 1% net margin versus -1256. 8% for TScan Therapeutics, Inc. — meaning it keeps 0. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CVKD leads at 0. 0% versus -1315. 4% for TCRX. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is CVKD or TCRX or IMVT or AGEN or RCUS more undervalued right now?

Analyst consensus price targets imply the most upside for TCRX: 519.

8% to $7. 50.

07

Which pays a better dividend — CVKD or TCRX or IMVT or AGEN or RCUS?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is CVKD or TCRX or IMVT or AGEN or RCUS better for a retirement portfolio?

For long-horizon retirement investors, Immunovant, Inc.

(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). Agenus Inc. (AGEN) carries a higher beta of 2. 72 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, AGEN: -94. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between CVKD and TCRX and IMVT and AGEN and RCUS?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: CVKD is a small-cap quality compounder stock; TCRX is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; AGEN is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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