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CVKD vs TCRX vs IMVT vs AGEN vs RCUS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
CVKD vs TCRX vs IMVT vs AGEN vs RCUS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $15M | $157M | $5.53B | $132M | $2.50B |
| Revenue (TTM) | $0.00 | $8M | $0.00 | $114M | $236M |
| Net Income (TTM) | $-9M | $-124M | $-464M | $115K | $-369M |
| Gross Margin | — | 81.7% | — | 35.7% | 90.7% |
| Operating Margin | — | -15.8% | — | -17.7% | -168.6% |
| Forward P/E | — | — | — | 1.8x | — |
| Total Debt | $0.00 | $94M | $98K | $10M | $99M |
| Cash & Equiv. | $4M | $152M | $714M | $3M | $222M |
CVKD vs TCRX vs IMVT vs AGEN vs RCUS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jan 23 | May 26 | Return |
|---|---|---|---|
| Cadrenal Therapeuti… (CVKD) | 100 | 14.4 | -85.6% |
| TScan Therapeutics,… (TCRX) | 100 | 66.5 | -33.5% |
| Immunovant, Inc. (IMVT) | 100 | 153.2 | +53.2% |
| Agenus Inc. (AGEN) | 100 | 7.2 | -92.8% |
| Arcus Biosciences, … (RCUS) | 100 | 114.6 | +14.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CVKD vs TCRX vs IMVT vs AGEN vs RCUS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CVKD has the current edge in this matchup, primarily because of its strength in quality.
- 5.2% margin vs TCRX's -15.2%
TCRX is the #2 pick in this set and the best alternative if growth is your priority.
- 266.7% revenue growth vs CVKD's -52.9%
IMVT ranks third and is worth considering specifically for income & stability and long-term compounding.
- beta 1.37
- 173.6% 10Y total return vs RCUS's 45.9%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
AGEN is the clearest fit if your priority is growth exposure.
- Rev growth 10.4%, EPS growth 100.0%, 3Y rev CAGR 5.2%
- 0.1% ROA vs CVKD's -217.7%
RCUS is the clearest fit if your priority is momentum.
- +209.6% vs CVKD's -63.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 266.7% revenue growth vs CVKD's -52.9% | |
| Quality / Margins | 5.2% margin vs TCRX's -15.2% | |
| Stability / Safety | Beta 1.37 vs AGEN's 2.72 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +209.6% vs CVKD's -63.0% | |
| Efficiency (ROA) | 0.1% ROA vs CVKD's -217.7% |
CVKD vs TCRX vs IMVT vs AGEN vs RCUS — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
CVKD vs TCRX vs IMVT vs AGEN vs RCUS — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
AGEN leads in 2 of 6 categories
IMVT leads 2 • CVKD leads 0 • TCRX leads 0 • RCUS leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
AGEN leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
RCUS and IMVT operate at a comparable scale, with $236M and $0 in trailing revenue. AGEN is the more profitable business, keeping 0.1% of every revenue dollar as net income compared to TCRX's -15.2%. On growth, AGEN holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $8M | $0 | $114M | $236M |
| EBITDAEarnings before interest/tax | -$12M | -$127M | -$487M | -$10M | -$391M |
| Net IncomeAfter-tax profit | -$9M | -$124M | -$464M | $115,000 | -$369M |
| Free Cash FlowCash after capex | -$11M | -$125M | -$423M | -$159M | -$489M |
| Gross MarginGross profit ÷ Revenue | — | +81.7% | — | +35.7% | +90.7% |
| Operating MarginEBIT ÷ Revenue | — | -15.8% | — | -17.7% | -168.6% |
| Net MarginNet income ÷ Revenue | — | -15.2% | — | +0.1% | -156.4% |
| FCF MarginFCF ÷ Revenue | — | -15.3% | — | -139.1% | -2.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -100.0% | — | +27.5% | -39.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +50.2% | +15.4% | +19.7% | +85.3% | +10.5% |
Valuation Metrics
AGEN leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $15M | $157M | $5.5B | $132M | $2.5B |
| Enterprise ValueMkt cap + debt − cash | $11M | $99M | $4.8B | $140M | $2.4B |
| Trailing P/EPrice ÷ TTM EPS | -0.91x | -1.21x | -9.97x | -1102.94x | -7.54x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 1.79x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 15.22x | — | 1.16x | 10.11x |
| Price / BookPrice ÷ Book value/share | 4.38x | 1.28x | 5.83x | — | 4.22x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
Evenly matched — IMVT and AGEN each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-3 for CVKD. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to TCRX's 0.76x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs RCUS's 0/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -3.2% | -91.9% | -47.1% | — | -69.0% |
| ROA (TTM)Return on assets | -2.2% | -50.1% | -44.1% | +0.1% | -35.3% |
| ROICReturn on invested capital | — | -90.7% | — | — | -64.1% |
| ROCEReturn on capital employed | -2.6% | -49.8% | -66.1% | — | -42.1% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 2 | 2 | 6 | 0 |
| Debt / EquityFinancial leverage | — | 0.76x | 0.00x | — | 0.16x |
| Net DebtTotal debt minus cash | -$4M | -$58M | -$714M | $7M | -$123M |
| Cash & Equiv.Liquid assets | $4M | $152M | $714M | $3M | $222M |
| Total DebtShort + long-term debt | $0 | $94M | $98,000 | $10M | $99M |
| Interest CoverageEBIT ÷ Interest expense | — | -73.07x | — | 1.11x | -13.38x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $611 for AGEN. Over the past 12 months, RCUS leads with a +209.6% total return vs CVKD's -63.0%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs AGEN's -51.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -17.9% | +18.6% | +5.1% | +16.1% | +6.5% |
| 1-Year ReturnPast 12 months | -63.0% | -11.0% | +96.1% | +27.1% | +209.6% |
| 3-Year ReturnCumulative with dividends | -71.7% | -46.2% | +40.9% | -88.2% | +24.9% |
| 5-Year ReturnCumulative with dividends | -90.3% | -88.5% | +62.4% | -93.9% | -18.6% |
| 10-Year ReturnCumulative with dividends | -90.3% | -88.5% | +173.6% | -94.3% | +45.9% |
| CAGR (3Y)Annualised 3-year return | -34.4% | -18.7% | +12.1% | -51.0% | +7.7% |
Risk & Volatility
IMVT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs CVKD's 36.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.12x | 2.35x | 1.37x | 2.72x | 1.95x |
| 52-Week HighHighest price in past year | $16.50 | $2.57 | $30.09 | $7.34 | $28.72 |
| 52-Week LowLowest price in past year | $4.20 | $0.88 | $13.36 | $2.71 | $7.06 |
| % of 52W HighCurrent price vs 52-week peak | +36.5% | +47.1% | +90.5% | +51.1% | +86.3% |
| RSI (14)Momentum oscillator 0–100 | 54.7 | 56.8 | 60.2 | 48.8 | 60.5 |
| Avg Volume (50D)Average daily shares traded | 53K | 910K | 1.4M | 814K | 1.2M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: TCRX as "Buy", IMVT as "Buy", AGEN as "Buy", RCUS as "Buy". Consensus price targets imply 519.8% upside for TCRX (target: $8) vs 21.0% for RCUS (target: $30).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $7.50 | $45.50 | $7.33 | $30.00 |
| # AnalystsCovering analysts | — | 8 | 23 | 11 | 18 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | 1 | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +1.9% | 0.0% | 0.0% | +0.1% | 0.0% |
AGEN leads in 2 of 6 categories (Income & Cash Flow, Valuation Metrics). IMVT leads in 2 (Total Returns, Risk & Volatility). 1 tied.
CVKD vs TCRX vs IMVT vs AGEN vs RCUS: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is CVKD or TCRX or IMVT or AGEN or RCUS a better buy right now?
For growth investors, TScan Therapeutics, Inc.
(TCRX) is the stronger pick with 266. 7% revenue growth year-over-year, versus -4. 3% for Arcus Biosciences, Inc. (RCUS). Analysts rate TScan Therapeutics, Inc. (TCRX) a "Buy" — based on 8 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — CVKD or TCRX or IMVT or AGEN or RCUS?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -93. 9% for Agenus Inc. (AGEN). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus AGEN's -94. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — CVKD or TCRX or IMVT or AGEN or RCUS?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 37β versus Agenus Inc. 's 2. 72β — meaning AGEN is approximately 98% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 76% for TScan Therapeutics, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — CVKD or TCRX or IMVT or AGEN or RCUS?
By revenue growth (latest reported year), TScan Therapeutics, Inc.
(TCRX) is pulling ahead at 266. 7% versus -4. 3% for Arcus Biosciences, Inc. (RCUS). On earnings-per-share growth, the picture is similar: Agenus Inc. grew EPS 100. 0% year-over-year, compared to -45. 2% for Immunovant, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — CVKD or TCRX or IMVT or AGEN or RCUS?
Agenus Inc.
(AGEN) is the more profitable company, earning 0. 1% net margin versus -1256. 8% for TScan Therapeutics, Inc. — meaning it keeps 0. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CVKD leads at 0. 0% versus -1315. 4% for TCRX. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is CVKD or TCRX or IMVT or AGEN or RCUS more undervalued right now?
Analyst consensus price targets imply the most upside for TCRX: 519.
8% to $7. 50.
07Which pays a better dividend — CVKD or TCRX or IMVT or AGEN or RCUS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is CVKD or TCRX or IMVT or AGEN or RCUS better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). Agenus Inc. (AGEN) carries a higher beta of 2. 72 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, AGEN: -94. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between CVKD and TCRX and IMVT and AGEN and RCUS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CVKD is a small-cap quality compounder stock; TCRX is a small-cap high-growth stock; IMVT is a small-cap quality compounder stock; AGEN is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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