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DRTS vs RLAY vs KYMR vs NVCR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Instruments & Supplies
DRTS vs RLAY vs KYMR vs NVCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Medical - Instruments & Supplies |
| Market Cap | $691M | $2.37B | $6.91B | $1.92B |
| Revenue (TTM) | $0.00 | $11M | $51M | $674M |
| Net Income (TTM) | $-43M | $-273M | $-315M | $-173M |
| Gross Margin | — | 66.3% | 33.2% | 75.2% |
| Operating Margin | — | -27.8% | -7.0% | -27.2% |
| Total Debt | $14M | $32M | $82M | $290M |
| Cash & Equiv. | $16M | $84M | $357M | $103M |
DRTS vs RLAY vs KYMR vs NVCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Mar 21 | May 26 | Return |
|---|---|---|---|
| Alpha Tau Medical L… (DRTS) | 100 | 88.1 | -11.9% |
| Relay Therapeutics,… (RLAY) | 100 | 36.9 | -63.1% |
| Kymera Therapeutics… (KYMR) | 100 | 221.5 | +121.5% |
| NovoCure Limited (NVCR) | 100 | 13.5 | -86.5% |
Price return only. Dividends and distributions are not included.
Quick Verdict: DRTS vs RLAY vs KYMR vs NVCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
DRTS is the #2 pick in this set and the best alternative if quality is your priority.
- 3.2% margin vs RLAY's -25.5%
RLAY carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 53.4%, EPS growth 31.8%, 3Y rev CAGR 123.2%
- 53.4% revenue growth vs DRTS's -115.8%
- +324.1% vs NVCR's +1.1%
KYMR is the clearest fit if your priority is income & stability and long-term compounding.
- beta 1.15
- 154.4% 10Y total return vs DRTS's -22.3%
- Lower volatility, beta 1.15, Low D/E 5.2%, current ratio 10.47x
- Beta 1.15, current ratio 10.47x
NVCR is the clearest fit if your priority is efficiency.
- -16.5% ROA vs DRTS's -42.3%, ROIC -16.4% vs -46.5%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 53.4% revenue growth vs DRTS's -115.8% | |
| Quality / Margins | 3.2% margin vs RLAY's -25.5% | |
| Stability / Safety | Beta 1.15 vs NVCR's 2.20, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +324.1% vs NVCR's +1.1% | |
| Efficiency (ROA) | -16.5% ROA vs DRTS's -42.3%, ROIC -16.4% vs -46.5% |
DRTS vs RLAY vs KYMR vs NVCR — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
NVCR leads in 1 of 6 categories
KYMR leads 1 • DRTS leads 0 • RLAY leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
NVCR leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
NVCR and DRTS operate at a comparable scale, with $674M and $0 in trailing revenue. Profitability is closely matched — net margins range from -25.7% (NVCR) to -25.5% (RLAY). On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $11M | $51M | $674M |
| EBITDAEarnings before interest/tax | $18M | -$298M | -$352M | -$165M |
| Net IncomeAfter-tax profit | -$43M | -$273M | -$315M | -$173M |
| Free Cash FlowCash after capex | -$33M | -$213M | -$244M | -$48M |
| Gross MarginGross profit ÷ Revenue | — | +66.3% | +33.2% | +75.2% |
| Operating MarginEBIT ÷ Revenue | — | -27.8% | -7.0% | -27.2% |
| Net MarginNet income ÷ Revenue | — | -25.5% | -6.1% | -25.7% |
| FCF MarginFCF ÷ Revenue | — | -20.0% | -4.7% | -7.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -60.9% | +55.5% | +12.3% |
| EPS Growth (YoY)Latest quarter vs prior year | 0.0% | +10.9% | +13.4% | -100.0% |
Valuation Metrics
Evenly matched — RLAY and KYMR and NVCR each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $691M | $2.4B | $6.9B | $1.9B |
| Enterprise ValueMkt cap + debt − cash | $689M | $2.3B | $6.6B | $2.1B |
| Trailing P/EPrice ÷ TTM EPS | -14.81x | -7.77x | -22.93x | -13.80x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | 154.15x | 176.26x | 2.92x |
| Price / BookPrice ÷ Book value/share | 8.20x | 3.79x | 4.52x | 5.51x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
Evenly matched — KYMR and NVCR each lead in 4 of 9 comparable metrics.
Profitability & Efficiency
KYMR delivers a -25.0% return on equity — every $100 of shareholder capital generates $-25 in annual profit, vs $-57 for DRTS. KYMR carries lower financial leverage with a 0.05x debt-to-equity ratio, signaling a more conservative balance sheet compared to NVCR's 0.85x. On the Piotroski fundamental quality scale (0–9), RLAY scores 5/9 vs DRTS's 3/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -57.3% | -43.9% | -25.0% | -50.8% |
| ROA (TTM)Return on assets | -42.3% | -40.1% | -22.3% | -16.5% |
| ROICReturn on invested capital | -46.5% | -37.3% | -24.9% | -16.4% |
| ROCEReturn on capital employed | -48.7% | -42.7% | -27.2% | -28.9% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 5 | 4 | 5 |
| Debt / EquityFinancial leverage | 0.18x | 0.06x | 0.05x | 0.85x |
| Net DebtTotal debt minus cash | -$2M | -$52M | -$275M | $187M |
| Cash & Equiv.Liquid assets | $16M | $84M | $357M | $103M |
| Total DebtShort + long-term debt | $14M | $32M | $82M | $290M |
| Interest CoverageEBIT ÷ Interest expense | -100.93x | — | -2119.53x | -96.80x |
Total Returns (Dividends Reinvested)
KYMR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in KYMR five years ago would be worth $19,212 today (with dividends reinvested), compared to $875 for NVCR. Over the past 12 months, RLAY leads with a +324.1% total return vs NVCR's +1.1%. The 3-year compound annual growth rate (CAGR) favors KYMR at 45.0% vs NVCR's -37.6% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +62.5% | +52.9% | +16.3% | +28.3% |
| 1-Year ReturnPast 12 months | +188.6% | +324.1% | +190.7% | +1.1% |
| 3-Year ReturnCumulative with dividends | +149.2% | +15.6% | +205.1% | -75.7% |
| 5-Year ReturnCumulative with dividends | -19.2% | -57.6% | +92.1% | -91.3% |
| 10-Year ReturnCumulative with dividends | -22.3% | -64.3% | +154.4% | +30.3% |
| CAGR (3Y)Annualised 3-year return | +35.6% | +5.0% | +45.0% | -37.6% |
Risk & Volatility
Evenly matched — DRTS and KYMR each lead in 1 of 2 comparable metrics.
Risk & Volatility
KYMR is the less volatile stock with a 1.15 beta — it tends to amplify market swings less than NVCR's 2.20 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DRTS currently trades 86.5% from its 52-week high vs RLAY's 72.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.77x | 1.77x | 1.03x | 2.15x |
| 52-Week HighHighest price in past year | $9.07 | $17.31 | $103.00 | $20.06 |
| 52-Week LowLowest price in past year | $2.57 | $2.67 | $28.06 | $9.82 |
| % of 52W HighCurrent price vs 52-week peak | +86.5% | +72.3% | +82.2% | +83.9% |
| RSI (14)Momentum oscillator 0–100 | 49.4 | 45.9 | 54.1 | 69.8 |
| Avg Volume (50D)Average daily shares traded | 328K | 3.1M | 602K | 1.5M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: DRTS as "Buy", RLAY as "Buy", KYMR as "Buy", NVCR as "Buy". Consensus price targets imply 99.0% upside for NVCR (target: $34) vs 39.5% for KYMR (target: $118).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $12.00 | $21.60 | $118.06 | $33.50 |
| # AnalystsCovering analysts | 4 | 15 | 26 | 15 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% |
NVCR leads in 1 of 6 categories (Income & Cash Flow). KYMR leads in 1 (Total Returns). 3 tied.
DRTS vs RLAY vs KYMR vs NVCR: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is DRTS or RLAY or KYMR or NVCR a better buy right now?
For growth investors, Relay Therapeutics, Inc.
(RLAY) is the stronger pick with 53. 4% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). Analysts rate Alpha Tau Medical Ltd. (DRTS) a "Buy" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — DRTS or RLAY or KYMR or NVCR?
Over the past 5 years, Kymera Therapeutics, Inc.
(KYMR) delivered a total return of +92. 1%, compared to -91. 3% for NovoCure Limited (NVCR). Over 10 years, the gap is even starker: KYMR returned +158. 8% versus RLAY's -63. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — DRTS or RLAY or KYMR or NVCR?
By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.
(KYMR) is the lower-risk stock at 1. 03β versus NovoCure Limited's 2. 15β — meaning NVCR is approximately 109% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Kymera Therapeutics, Inc. (KYMR) carries a lower debt/equity ratio of 5% versus 85% for NovoCure Limited — giving it more financial flexibility in a downturn.
04Which is growing faster — DRTS or RLAY or KYMR or NVCR?
By revenue growth (latest reported year), Relay Therapeutics, Inc.
(RLAY) is pulling ahead at 53. 4% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Relay Therapeutics, Inc. grew EPS 31. 8% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Over a 3-year CAGR, RLAY leads at 123. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — DRTS or RLAY or KYMR or NVCR?
Alpha Tau Medical Ltd.
(DRTS) is the more profitable company, earning 0. 0% net margin versus -1800. 6% for Relay Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DRTS leads at 0. 0% versus -1971. 6% for RLAY. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — DRTS or RLAY or KYMR or NVCR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is DRTS or RLAY or KYMR or NVCR better for a retirement portfolio?
For long-horizon retirement investors, Kymera Therapeutics, Inc.
(KYMR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 03), +158. 8% 10Y return). NovoCure Limited (NVCR) carries a higher beta of 2. 15 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KYMR: +158. 8%, NVCR: +38. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between DRTS and RLAY and KYMR and NVCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: DRTS is a small-cap quality compounder stock; RLAY is a small-cap high-growth stock; KYMR is a small-cap quality compounder stock; NVCR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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