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EBS vs JNJ vs PFE vs MRK

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
EBS
Emergent BioSolutions Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNYSE • US
Market Cap$472M
5Y Perf.-89.1%
JNJ
Johnson & Johnson

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$536.23B
5Y Perf.+49.6%
PFE
Pfizer Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$150.63B
5Y Perf.-26.9%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.+45.9%

EBS vs JNJ vs PFE vs MRK — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
EBS logoEBS
JNJ logoJNJ
PFE logoPFE
MRK logoMRK
IndustryDrug Manufacturers - Specialty & GenericDrug Manufacturers - GeneralDrug Manufacturers - GeneralDrug Manufacturers - General
Market Cap$472M$536.23B$150.63B$277.34B
Revenue (TTM)$743M$92.15B$63.31B$64.93B
Net Income (TTM)$53M$25.12B$7.49B$18.25B
Gross Margin47.1%68.1%69.3%74.2%
Operating Margin14.7%26.1%23.4%41.1%
Forward P/E17.6x19.2x8.9x21.9x
Total Debt$572M$36.63B$67.42B$50.53B
Cash & Equiv.$205M$24.11B$1.14B$14.56B

EBS vs JNJ vs PFE vs MRKLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

EBS
JNJ
PFE
MRK
StockMay 20May 26Return
Emergent BioSolutio… (EBS)10010.9-89.1%
Johnson & Johnson (JNJ)100149.6+49.6%
Pfizer Inc. (PFE)10073.1-26.9%
Merck & Co., Inc. (MRK)100145.9+45.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: EBS vs JNJ vs PFE vs MRK

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JNJ and PFE are tied at the top with 2 categories each — the right choice depends on your priorities. Pfizer Inc. is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. MRK and EBS also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
EBS
Emergent BioSolutions Inc.
The Momentum Pick

EBS is the clearest fit if your priority is momentum.

  • +92.7% vs PFE's +23.7%
Best for: momentum
JNJ
Johnson & Johnson
The Growth Play

JNJ has the current edge in this matchup, primarily because of its strength in growth exposure and sleep-well-at-night.

  • Rev growth 4.3%, EPS growth -57.8%, 3Y rev CAGR 4.1%
  • Lower volatility, beta 0.06, Low D/E 51.2%, current ratio 1.11x
  • 4.3% revenue growth vs EBS's -28.8%
  • Beta 0.06 vs EBS's 1.83, lower leverage
Best for: growth exposure and sleep-well-at-night
PFE
Pfizer Inc.
The Income Pick

PFE is the #2 pick in this set and the best alternative if income & stability is your priority.

  • Dividend streak 15 yrs, beta 0.54, yield 6.5%
  • Lower P/E (8.9x vs 19.2x)
  • 6.5% yield, 15-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Best for: income & stability
MRK
Merck & Co., Inc.
The Long-Run Compounder

MRK is the clearest fit if your priority is long-term compounding and valuation efficiency.

  • 166.5% 10Y total return vs JNJ's 132.3%
  • PEG 1.03 vs JNJ's 34.17
  • Beta 0.48, yield 2.9%, current ratio 1.54x
  • 28.1% margin vs EBS's 7.1%
Best for: long-term compounding and valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthJNJ logoJNJ4.3% revenue growth vs EBS's -28.8%
ValuePFE logoPFELower P/E (8.9x vs 19.2x)
Quality / MarginsMRK logoMRK28.1% margin vs EBS's 7.1%
Stability / SafetyJNJ logoJNJBeta 0.06 vs EBS's 1.83, lower leverage
DividendsPFE logoPFE6.5% yield, 15-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
Momentum (1Y)EBS logoEBS+92.7% vs PFE's +23.7%
Efficiency (ROA)MRK logoMRK14.6% ROA vs PFE's 3.6%, ROIC 22.0% vs 7.5%

EBS vs JNJ vs PFE vs MRK — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

EBSEmergent BioSolutions Inc.
FY 2025
Product
94.9%$705M
Contracts and Grants
5.1%$38M
JNJJohnson & Johnson
FY 2024
Innovative Medicine
64.1%$57.0B
MedTech
35.9%$31.9B
PFEPfizer Inc.
FY 2025
Biopharma Segment
97.8%$61.2B
Segment Reporting, Reconciling Item, Corporate Nonsegment
2.2%$1.4B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M

EBS vs JNJ vs PFE vs MRK — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLMRKLAGGINGPFE

Income & Cash Flow (Last 12 Months)

MRK leads this category, winning 3 of 6 comparable metrics.

JNJ is the larger business by revenue, generating $92.1B annually — 124.0x EBS's $743M. MRK is the more profitable business, keeping 28.1% of every revenue dollar as net income compared to EBS's 7.1%. On growth, JNJ holds the edge at +6.8% YoY revenue growth, suggesting stronger near-term business momentum.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.
RevenueTrailing 12 months$743M$92.1B$63.3B$64.9B
EBITDAEarnings before interest/tax$207M$31.4B$21.0B$32.4B
Net IncomeAfter-tax profit$53M$25.1B$7.5B$18.3B
Free Cash FlowCash after capex$157M$19.1B$9.5B$12.4B
Gross MarginGross profit ÷ Revenue+47.1%+68.1%+69.3%+74.2%
Operating MarginEBIT ÷ Revenue+14.7%+26.1%+23.4%+41.1%
Net MarginNet income ÷ Revenue+7.1%+27.3%+11.8%+28.1%
FCF MarginFCF ÷ Revenue+21.1%+20.7%+15.0%+19.0%
Rev. Growth (YoY)Latest quarter vs prior year-23.6%+6.8%+5.4%+4.5%
EPS Growth (YoY)Latest quarter vs prior year-76.3%+91.0%-9.5%-19.6%
MRK leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

EBS leads this category, winning 5 of 7 comparable metrics.

At 9.8x trailing earnings, EBS trades at a 74% valuation discount to JNJ's 38.4x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.73x vs JNJ's 34.17x — a lower PEG means you pay less per unit of expected earnings growth.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.
Market CapShares × price$472M$536.2B$150.6B$277.3B
Enterprise ValueMkt cap + debt − cash$838M$548.8B$216.9B$313.3B
Trailing P/EPrice ÷ TTM EPS9.82x38.43x19.47x15.42x
Forward P/EPrice ÷ next-FY EPS est.17.57x19.20x8.94x21.93x
PEG RatioP/E ÷ EPS growth rate34.17x0.73x
EV / EBITDAEnterprise value multiple4.02x18.61x10.66x10.68x
Price / SalesMarket cap ÷ Revenue0.64x6.04x2.41x4.27x
Price / BookPrice ÷ Book value/share0.99x7.56x1.74x5.35x
Price / FCFMarket cap ÷ FCF3.01x27.02x16.60x22.44x
EBS leads this category, winning 5 of 7 comparable metrics.

Profitability & Efficiency

MRK leads this category, winning 4 of 9 comparable metrics.

MRK delivers a 36.1% return on equity — every $100 of shareholder capital generates $36 in annual profit, vs $8 for PFE. JNJ carries lower financial leverage with a 0.51x debt-to-equity ratio, signaling a more conservative balance sheet compared to EBS's 1.09x. On the Piotroski fundamental quality scale (0–9), EBS scores 7/9 vs MRK's 4/9, reflecting strong financial health.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.
ROE (TTM)Return on equity+9.6%+31.7%+8.3%+36.1%
ROA (TTM)Return on assets+3.7%+13.0%+3.6%+14.6%
ROICReturn on invested capital+8.5%+20.7%+7.5%+22.0%
ROCEReturn on capital employed+9.1%+17.6%+9.0%+23.8%
Piotroski ScoreFundamental quality 0–97574
Debt / EquityFinancial leverage1.09x0.51x0.78x0.96x
Net DebtTotal debt minus cash$367M$12.5B$66.3B$36.0B
Cash & Equiv.Liquid assets$205M$24.1B$1.1B$14.6B
Total DebtShort + long-term debt$572M$36.6B$67.4B$50.5B
Interest CoverageEBIT ÷ Interest expense1.84x48.23x4.02x19.68x
MRK leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

JNJ leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in MRK five years ago would be worth $17,024 today (with dividends reinvested), compared to $1,482 for EBS. Over the past 12 months, EBS leads with a +92.7% total return vs PFE's +23.7%. The 3-year compound annual growth rate (CAGR) favors JNJ at 13.5% vs PFE's -6.6% — a key indicator of consistent wealth creation.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.
YTD ReturnYear-to-date-27.0%+7.9%+6.9%+6.3%
1-Year ReturnPast 12 months+92.7%+44.8%+23.7%+46.1%
3-Year ReturnCumulative with dividends+0.2%+46.3%-18.4%+2.9%
5-Year ReturnCumulative with dividends-85.2%+46.1%-13.3%+70.2%
10-Year ReturnCumulative with dividends-76.6%+132.3%+29.6%+166.5%
CAGR (3Y)Annualised 3-year return+0.1%+13.5%-6.6%+0.9%
JNJ leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.

JNJ is the less volatile stock with a 0.06 beta — it tends to amplify market swings less than EBS's 1.83 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 92.1% from its 52-week high vs EBS's 65.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.
Beta (5Y)Sensitivity to S&P 5001.83x0.06x0.54x0.48x
52-Week HighHighest price in past year$14.06$251.71$28.75$125.14
52-Week LowLowest price in past year$4.72$146.12$21.97$73.31
% of 52W HighCurrent price vs 52-week peak+65.0%+88.4%+92.1%+89.7%
RSI (14)Momentum oscillator 0–10061.437.144.246.7
Avg Volume (50D)Average daily shares traded873K7.0M33.3M7.3M
Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.

Analyst consensus: EBS as "Buy", JNJ as "Buy", PFE as "Hold", MRK as "Buy". Consensus price targets imply 31.4% upside for EBS (target: $12) vs 3.0% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.49% vs JNJ's 2.19%.

MetricEBS logoEBSEmergent BioSolut…JNJ logoJNJJohnson & JohnsonPFE logoPFEPfizer Inc.MRK logoMRKMerck & Co., Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyHoldBuy
Price TargetConsensus 12-month target$12.00$249.27$27.27$129.31
# AnalystsCovering analysts15403937
Dividend YieldAnnual dividend ÷ price+2.2%+6.5%+2.9%
Dividend StreakConsecutive years of raises1361514
Dividend / ShareAnnual DPS$4.87$1.72$3.26
Buyback YieldShare repurchases ÷ mkt cap+5.3%+0.5%0.0%+1.8%
Evenly matched — JNJ and PFE each lead in 1 of 2 comparable metrics.
Key Takeaway

MRK leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). EBS leads in 1 (Valuation Metrics). 2 tied.

Best OverallMerck & Co., Inc. (MRK)Leads 2 of 6 categories
Loading custom metrics...

EBS vs JNJ vs PFE vs MRK: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is EBS or JNJ or PFE or MRK a better buy right now?

For growth investors, Johnson & Johnson (JNJ) is the stronger pick with 4.

3% revenue growth year-over-year, versus -28. 8% for Emergent BioSolutions Inc. (EBS). Emergent BioSolutions Inc. (EBS) offers the better valuation at 9. 8x trailing P/E (17. 6x forward), making it the more compelling value choice. Analysts rate Emergent BioSolutions Inc. (EBS) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — EBS or JNJ or PFE or MRK?

On trailing P/E, Emergent BioSolutions Inc.

(EBS) is the cheapest at 9. 8x versus Johnson & Johnson at 38. 4x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Merck & Co. , Inc. wins at 1. 03x versus Johnson & Johnson's 34. 17x — a reasonable growth-adjusted valuation.

03

Which is the better long-term investment — EBS or JNJ or PFE or MRK?

Over the past 5 years, Merck & Co.

, Inc. (MRK) delivered a total return of +70. 2%, compared to -85. 2% for Emergent BioSolutions Inc. (EBS). Over 10 years, the gap is even starker: MRK returned +166. 5% versus EBS's -76. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — EBS or JNJ or PFE or MRK?

By beta (market sensitivity over 5 years), Johnson & Johnson (JNJ) is the lower-risk stock at 0.

06β versus Emergent BioSolutions Inc. 's 1. 83β — meaning EBS is approximately 3117% more volatile than JNJ relative to the S&P 500. On balance sheet safety, Johnson & Johnson (JNJ) carries a lower debt/equity ratio of 51% versus 109% for Emergent BioSolutions Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — EBS or JNJ or PFE or MRK?

By revenue growth (latest reported year), Johnson & Johnson (JNJ) is pulling ahead at 4.

3% versus -28. 8% for Emergent BioSolutions Inc. (EBS). On earnings-per-share growth, the picture is similar: Emergent BioSolutions Inc. grew EPS 125. 8% year-over-year, compared to -57. 8% for Johnson & Johnson. Over a 3-year CAGR, JNJ leads at 4. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — EBS or JNJ or PFE or MRK?

Merck & Co.

, Inc. (MRK) is the more profitable company, earning 28. 1% net margin versus 7. 1% for Emergent BioSolutions Inc. — meaning it keeps 28. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: MRK leads at 36. 2% versus 14. 8% for EBS. At the gross margin level — before operating expenses — MRK leads at 72. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is EBS or JNJ or PFE or MRK more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Merck & Co. , Inc. (MRK) is the more undervalued stock at a PEG of 1. 03x versus Johnson & Johnson's 34. 17x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, Pfizer Inc. (PFE) trades at 8. 9x forward P/E versus 21. 9x for Merck & Co. , Inc. — 13. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for EBS: 31. 4% to $12. 00.

08

Which pays a better dividend — EBS or JNJ or PFE or MRK?

In this comparison, PFE (6.

5% yield), MRK (2. 9% yield), JNJ (2. 2% yield) pay a dividend. EBS does not pay a meaningful dividend and should not be held primarily for income.

09

Is EBS or JNJ or PFE or MRK better for a retirement portfolio?

For long-horizon retirement investors, Johnson & Johnson (JNJ) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

06), 2. 2% yield, +132. 3% 10Y return). Emergent BioSolutions Inc. (EBS) carries a higher beta of 1. 83 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (JNJ: +132. 3%, EBS: -76. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between EBS and JNJ and PFE and MRK?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: EBS is a small-cap deep-value stock; JNJ is a large-cap quality compounder stock; PFE is a mid-cap income-oriented stock; MRK is a large-cap deep-value stock. JNJ, PFE, MRK pay a dividend while EBS does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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EBS

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  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 5%
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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 16%
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PFE

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
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MRK

Dividend Mega-Cap Quality

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 16%
  • Dividend Yield > 1.1%
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Beat Both

Find stocks that outperform EBS and JNJ and PFE and MRK on the metrics below

Revenue Growth>
%
(EBS: -23.6% · JNJ: 6.8%)
Net Margin>
%
(EBS: 7.1% · JNJ: 27.3%)
P/E Ratio<
x
(EBS: 9.8x · JNJ: 38.4x)

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