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IMRN vs HALO vs ADMA vs ALNY vs ABBV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IMRN
Immuron Limited

Biotechnology

HealthcareNASDAQ • AU
Market Cap$7M
5Y Perf.-60.4%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.55B
5Y Perf.+164.2%
ADMA
ADMA Biologics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.89B
5Y Perf.+148.3%
ALNY
Alnylam Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$39.37B
5Y Perf.+118.1%
ABBV
AbbVie Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$356.49B
5Y Perf.+117.5%

IMRN vs HALO vs ADMA vs ALNY vs ABBV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IMRN logoIMRN
HALO logoHALO
ADMA logoADMA
ALNY logoALNY
ABBV logoABBV
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyDrug Manufacturers - General
Market Cap$7M$7.55B$1.89B$39.37B$356.49B
Revenue (TTM)$11M$1.40B$510M$4.29B$61.16B
Net Income (TTM)$-8M$317M$165M$577M$4.23B
Gross Margin65.4%81.9%61.3%80.9%70.2%
Operating Margin-73.7%58.4%42.1%17.5%26.7%
Forward P/E8.0x9.7x39.9x14.2x
Total Debt$117K$0.00$80M$1.28B$69.07B
Cash & Equiv.$3M$134M$88M$1.66B$5.23B

IMRN vs HALO vs ADMA vs ALNY vs ABBVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IMRN
HALO
ADMA
ALNY
ABBV
StockMay 20May 26Return
Immuron Limited (IMRN)10039.6-60.4%
Halozyme Therapeuti… (HALO)100264.2+164.2%
ADMA Biologics, Inc. (ADMA)100248.3+148.3%
Alnylam Pharmaceuti… (ALNY)100218.1+118.1%
AbbVie Inc. (ABBV)100217.5+117.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: IMRN vs HALO vs ADMA vs ALNY vs ABBV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ADMA and ALNY are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Alnylam Pharmaceuticals, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. ABBV and HALO also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
IMRN
Immuron Limited
The Defensive Pick

IMRN is the clearest fit if your priority is sleep-well-at-night.

  • Lower volatility, beta 0.80, Low D/E 1.5%, current ratio 5.07x
Best for: sleep-well-at-night
HALO
Halozyme Therapeutics, Inc.
The Defensive Pick

HALO is the clearest fit if your priority is defensive.

  • Beta 0.51, current ratio 4.66x
  • Lower P/E (8.0x vs 14.2x)
Best for: defensive
ADMA
ADMA Biologics, Inc.
The Quality Compounder

ADMA has the current edge in this matchup, primarily because of its strength in quality and efficiency.

  • 32.4% margin vs IMRN's -71.9%
  • 27.4% ROA vs IMRN's -77.9%, ROIC 36.0% vs -122.5%
Best for: quality and efficiency
ALNY
Alnylam Pharmaceuticals, Inc.
The Growth Play

ALNY is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.

  • Rev growth 65.2%, EPS growth 206.9%, 3Y rev CAGR 53.0%
  • 410.4% 10Y total return vs HALO's 5.6%
  • 65.2% revenue growth vs ABBV's 8.6%
  • +14.2% vs ADMA's -61.5%
Best for: growth exposure and long-term compounding
ABBV
AbbVie Inc.
The Income Pick

ABBV ranks third and is worth considering specifically for income & stability.

  • Dividend streak 13 yrs, beta 0.28, yield 3.3%
  • Beta 0.28 vs ADMA's 1.25
  • 3.3% yield; 13-year raise streak; the other 4 pay no meaningful dividend
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthALNY logoALNY65.2% revenue growth vs ABBV's 8.6%
ValueHALO logoHALOLower P/E (8.0x vs 14.2x)
Quality / MarginsADMA logoADMA32.4% margin vs IMRN's -71.9%
Stability / SafetyABBV logoABBVBeta 0.28 vs ADMA's 1.25
DividendsABBV logoABBV3.3% yield; 13-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)ALNY logoALNY+14.2% vs ADMA's -61.5%
Efficiency (ROA)ADMA logoADMA27.4% ROA vs IMRN's -77.9%, ROIC 36.0% vs -122.5%

IMRN vs HALO vs ADMA vs ALNY vs ABBV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IMRNImmuron Limited
FY 2021
ProtectynMember
100.0%$50,181
HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M
ADMAADMA Biologics, Inc.
FY 2024
ADMA BioManufacturing Segment
97.4%$416M
Plasma Collection Centers Segment
2.6%$11M
ALNYAlnylam Pharmaceuticals, Inc.
FY 2025
GIVLAARI
64.1%$308M
ONPATTRO
35.9%$173M
ABBVAbbVie Inc.
FY 2025
SKYRIZI
30.2%$17.6B
RINVOQ
14.3%$8.3B
H U M I R A
7.8%$4.5B
Botox Therapeutic
6.5%$3.8B
Vraylar
6.2%$3.6B
Imbruvica
4.9%$2.9B
VENCLEXTA
4.8%$2.8B
Other (14)
25.3%$14.7B

IMRN vs HALO vs ADMA vs ALNY vs ABBV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLADMALAGGINGALNY

Income & Cash Flow (Last 12 Months)

HALO leads this category, winning 3 of 6 comparable metrics.

ABBV is the larger business by revenue, generating $61.2B annually — 5595.4x IMRN's $11M. ADMA is the more profitable business, keeping 32.4% of every revenue dollar as net income compared to IMRN's -71.9%. On growth, ALNY holds the edge at +96.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIMRN logoIMRNImmuron LimitedHALO logoHALOHalozyme Therapeu…ADMA logoADMAADMA Biologics, I…ALNY logoALNYAlnylam Pharmaceu…ABBV logoABBVAbbVie Inc.
RevenueTrailing 12 months$11M$1.4B$510M$4.3B$61.2B
EBITDAEarnings before interest/tax-$8M$945M$221M$677M$24.5B
Net IncomeAfter-tax profit-$8M$317M$165M$577M$4.2B
Free Cash FlowCash after capex-$9M$645M$108M$641M$18.7B
Gross MarginGross profit ÷ Revenue+65.4%+81.9%+61.3%+80.9%+70.2%
Operating MarginEBIT ÷ Revenue-73.7%+58.4%+42.1%+17.5%+26.7%
Net MarginNet income ÷ Revenue-71.9%+22.7%+32.4%+13.5%+6.9%
FCF MarginFCF ÷ Revenue-84.2%+46.2%+21.2%+15.0%+30.6%
Rev. Growth (YoY)Latest quarter vs prior year+29.3%+51.6%-0.3%+96.4%+10.0%
EPS Growth (YoY)Latest quarter vs prior year+45.3%-2.1%+72.7%+4.4%+57.4%
HALO leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — IMRN and HALO each lead in 3 of 6 comparable metrics.

At 13.6x trailing earnings, ADMA trades at a 89% valuation discount to ALNY's 126.6x P/E. On an enterprise value basis, HALO's 8.2x EV/EBITDA is more attractive than ALNY's 70.0x.

MetricIMRN logoIMRNImmuron LimitedHALO logoHALOHalozyme Therapeu…ADMA logoADMAADMA Biologics, I…ALNY logoALNYAlnylam Pharmaceu…ABBV logoABBVAbbVie Inc.
Market CapShares × price$7M$7.6B$1.9B$39.4B$356.5B
Enterprise ValueMkt cap + debt − cash$5M$7.4B$1.9B$39.0B$420.3B
Trailing P/EPrice ÷ TTM EPS-1.29x25.05x13.62x126.63x85.04x
Forward P/EPrice ÷ next-FY EPS est.7.96x9.69x39.92x14.17x
PEG RatioP/E ÷ EPS growth rate1.09x
EV / EBITDAEnterprise value multiple8.20x9.45x69.97x14.89x
Price / SalesMarket cap ÷ Revenue1.29x5.41x3.71x10.60x5.83x
Price / BookPrice ÷ Book value/share0.84x162.76x4.19x50.35x
Price / FCFMarket cap ÷ FCF11.72x68.06x84.59x20.01x
Evenly matched — IMRN and HALO each lead in 3 of 6 comparable metrics.

Profitability & Efficiency

ADMA leads this category, winning 3 of 9 comparable metrics.

ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-98 for IMRN. IMRN carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to ALNY's 1.62x. On the Piotroski fundamental quality scale (0–9), ALNY scores 6/9 vs IMRN's 1/9, reflecting solid financial health.

MetricIMRN logoIMRNImmuron LimitedHALO logoHALOHalozyme Therapeu…ADMA logoADMAADMA Biologics, I…ALNY logoALNYAlnylam Pharmaceu…ABBV logoABBVAbbVie Inc.
ROE (TTM)Return on equity-97.9%+6.5%+39.0%+98.3%+62.1%
ROA (TTM)Return on assets-77.9%+12.5%+27.4%+11.8%+3.1%
ROICReturn on invested capital-122.5%+73.4%+36.0%+33.4%+23.9%
ROCEReturn on capital employed-51.0%+38.2%+38.8%+15.3%+21.5%
Piotroski ScoreFundamental quality 0–915566
Debt / EquityFinancial leverage0.01x0.17x1.62x
Net DebtTotal debt minus cash-$3M-$134M-$8M-$379M$63.8B
Cash & Equiv.Liquid assets$3M$134M$88M$1.7B$5.2B
Total DebtShort + long-term debt$117,127$0$80M$1.3B$69.1B
Interest CoverageEBIT ÷ Interest expense-731.63x46.08x50.85x2.02x3.28x
ADMA leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

ADMA leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in ADMA five years ago would be worth $48,922 today (with dividends reinvested), compared to $1,640 for IMRN. Over the past 12 months, ALNY leads with a +14.2% total return vs ADMA's -61.5%. The 3-year compound annual growth rate (CAGR) favors ADMA at 32.7% vs IMRN's -32.1% — a key indicator of consistent wealth creation.

MetricIMRN logoIMRNImmuron LimitedHALO logoHALOHalozyme Therapeu…ADMA logoADMAADMA Biologics, I…ALNY logoALNYAlnylam Pharmaceu…ABBV logoABBVAbbVie Inc.
YTD ReturnYear-to-date+5.6%-8.8%-54.3%-26.3%-10.6%
1-Year ReturnPast 12 months-56.9%-5.3%-61.5%+14.2%+12.2%
3-Year ReturnCumulative with dividends-68.7%+111.8%+133.4%+40.5%+49.7%
5-Year ReturnCumulative with dividends-83.6%+39.1%+389.2%+129.4%+99.6%
10-Year ReturnCumulative with dividends-90.0%+559.7%+34.8%+410.4%+293.8%
CAGR (3Y)Annualised 3-year return-32.1%+28.4%+32.7%+12.0%+14.4%
ADMA leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

ABBV leads this category, winning 2 of 2 comparable metrics.

ABBV is the less volatile stock with a 0.28 beta — it tends to amplify market swings less than ADMA's 1.25 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ABBV currently trades 82.3% from its 52-week high vs IMRN's 35.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIMRN logoIMRNImmuron LimitedHALO logoHALOHalozyme Therapeu…ADMA logoADMAADMA Biologics, I…ALNY logoALNYAlnylam Pharmaceu…ABBV logoABBVAbbVie Inc.
Beta (5Y)Sensitivity to S&P 5000.80x0.51x1.25x0.74x0.28x
52-Week HighHighest price in past year$2.39$82.22$22.73$495.55$244.81
52-Week LowLowest price in past year$0.68$47.50$7.21$245.96$176.57
% of 52W HighCurrent price vs 52-week peak+35.1%+78.0%+35.9%+59.5%+82.3%
RSI (14)Momentum oscillator 0–10050.247.726.039.943.9
Avg Volume (50D)Average daily shares traded26K1.4M7.4M1.1M5.8M
ABBV leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

ABBV leads this category, winning 1 of 1 comparable metric.

Analyst consensus: HALO as "Buy", ADMA as "Buy", ALNY as "Buy", ABBV as "Buy". Consensus price targets imply 157.0% upside for ADMA (target: $21) vs 17.9% for HALO (target: $76). ABBV is the only dividend payer here at 3.26% yield — a key consideration for income-focused portfolios.

MetricIMRN logoIMRNImmuron LimitedHALO logoHALOHalozyme Therapeu…ADMA logoADMAADMA Biologics, I…ALNY logoALNYAlnylam Pharmaceu…ABBV logoABBVAbbVie Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuy
Price TargetConsensus 12-month target$75.60$21.00$445.67$256.69
# AnalystsCovering analysts27105241
Dividend YieldAnnual dividend ÷ price+3.3%
Dividend StreakConsecutive years of raises113
Dividend / ShareAnnual DPS$6.57
Buyback YieldShare repurchases ÷ mkt cap0.0%+4.5%+1.7%0.0%+0.3%
ABBV leads this category, winning 1 of 1 comparable metric.
Key Takeaway

ADMA leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). ABBV leads in 2 (Risk & Volatility, Analyst Outlook). 1 tied.

Best OverallADMA Biologics, Inc. (ADMA)Leads 2 of 6 categories
Loading custom metrics...

IMRN vs HALO vs ADMA vs ALNY vs ABBV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is IMRN or HALO or ADMA or ALNY or ABBV a better buy right now?

For growth investors, Alnylam Pharmaceuticals, Inc.

(ALNY) is the stronger pick with 65. 2% revenue growth year-over-year, versus 8. 6% for AbbVie Inc. (ABBV). ADMA Biologics, Inc. (ADMA) offers the better valuation at 13. 6x trailing P/E (9. 7x forward), making it the more compelling value choice. Analysts rate Halozyme Therapeutics, Inc. (HALO) a "Buy" — based on 27 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — IMRN or HALO or ADMA or ALNY or ABBV?

On trailing P/E, ADMA Biologics, Inc.

(ADMA) is the cheapest at 13. 6x versus Alnylam Pharmaceuticals, Inc. at 126. 6x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 0x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — IMRN or HALO or ADMA or ALNY or ABBV?

Over the past 5 years, ADMA Biologics, Inc.

(ADMA) delivered a total return of +389. 2%, compared to -83. 6% for Immuron Limited (IMRN). Over 10 years, the gap is even starker: HALO returned +559. 7% versus IMRN's -90. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — IMRN or HALO or ADMA or ALNY or ABBV?

By beta (market sensitivity over 5 years), AbbVie Inc.

(ABBV) is the lower-risk stock at 0. 28β versus ADMA Biologics, Inc. 's 1. 25β — meaning ADMA is approximately 354% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Immuron Limited (IMRN) carries a lower debt/equity ratio of 1% versus 162% for Alnylam Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — IMRN or HALO or ADMA or ALNY or ABBV?

By revenue growth (latest reported year), Alnylam Pharmaceuticals, Inc.

(ALNY) is pulling ahead at 65. 2% versus 8. 6% for AbbVie Inc. (ABBV). On earnings-per-share growth, the picture is similar: Alnylam Pharmaceuticals, Inc. grew EPS 206. 9% year-over-year, compared to -25. 9% for ADMA Biologics, Inc.. Over a 3-year CAGR, IMRN leads at 112. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — IMRN or HALO or ADMA or ALNY or ABBV?

ADMA Biologics, Inc.

(ADMA) is the more profitable company, earning 28. 8% net margin versus -71. 6% for Immuron Limited — meaning it keeps 28. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus -73. 3% for IMRN. At the gross margin level — before operating expenses — ALNY leads at 81. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is IMRN or HALO or ADMA or ALNY or ABBV more undervalued right now?

On forward earnings alone, Halozyme Therapeutics, Inc.

(HALO) trades at 8. 0x forward P/E versus 39. 9x for Alnylam Pharmaceuticals, Inc. — 32. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ADMA: 157. 0% to $21. 00.

08

Which pays a better dividend — IMRN or HALO or ADMA or ALNY or ABBV?

In this comparison, ABBV (3.

3% yield) pays a dividend. IMRN, HALO, ADMA, ALNY do not pay a meaningful dividend and should not be held primarily for income.

09

Is IMRN or HALO or ADMA or ALNY or ABBV better for a retirement portfolio?

For long-horizon retirement investors, AbbVie Inc.

(ABBV) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 28), 3. 3% yield, +293. 8% 10Y return). Both have compounded well over 10 years (ABBV: +293. 8%, ADMA: +34. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between IMRN and HALO and ADMA and ALNY and ABBV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: IMRN is a small-cap high-growth stock; HALO is a small-cap high-growth stock; ADMA is a small-cap high-growth stock; ALNY is a mid-cap high-growth stock; ABBV is a large-cap income-oriented stock. ABBV pays a dividend while IMRN, HALO, ADMA, ALNY do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Revenue Growth>
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(IMRN: 29.3% · HALO: 51.6%)

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