Biotechnology
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MBX vs DBVT vs HALO vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
MBX vs DBVT vs HALO vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $1.83B | $1690.08T | $7.55B | $74.28B |
| Revenue (TTM) | $0.00 | $0.00 | $1.40B | $14.92B |
| Net Income (TTM) | $-80M | $-168M | $317M | $4.42B |
| Gross Margin | — | — | 81.9% | 84.5% |
| Operating Margin | — | — | 58.4% | 24.3% |
| Forward P/E | — | — | 8.0x | 15.5x |
| Total Debt | $171K | $22M | $0.00 | $2.71B |
| Cash & Equiv. | $49M | $194M | $134M | $3.12B |
MBX vs DBVT vs HALO vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 24 | May 26 | Return |
|---|---|---|---|
| MBX Biosciences, In… (MBX) | 100 | 157.7 | +57.7% |
| DBV Technologies S.… (DBVT) | 100 | 450.5 | +350.5% |
| Halozyme Therapeuti… (HALO) | 100 | 112.0 | +12.0% |
| Regeneron Pharmaceu… (REGN) | 100 | 68.0 | -32.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MBX vs DBVT vs HALO vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MBX is the clearest fit if your priority is momentum.
- +249.8% vs HALO's -5.3%
DBVT lags the leaders in this set but could rank higher in a more targeted comparison.
HALO carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 37.6%, EPS growth -25.4%, 3Y rev CAGR 28.4%
- 5.6% 10Y total return vs REGN's 91.6%
- Lower volatility, beta 0.51, current ratio 4.66x
- PEG 0.35 vs REGN's 2.44
REGN is the #2 pick in this set and the best alternative if income & stability is your priority.
- Dividend streak 1 yrs, beta 0.77, yield 0.5%
- 29.6% margin vs DBVT's 0.3%
- 0.5% yield; 1-year raise streak; the other 3 pay no meaningful dividend
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 37.6% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (8.0x vs 15.5x), PEG 0.35 vs 2.44 | |
| Quality / Margins | 29.6% margin vs DBVT's 0.3% | |
| Stability / Safety | Beta 0.51 vs MBX's 1.33 | |
| Dividends | 0.5% yield; 1-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +249.8% vs HALO's -5.3% | |
| Efficiency (ROA) | 12.5% ROA vs DBVT's -89.0% |
MBX vs DBVT vs HALO vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
MBX vs DBVT vs HALO vs REGN — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
HALO leads in 3 of 6 categories
REGN leads 1 • MBX leads 0 • DBVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
HALO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
REGN and DBVT operate at a comparable scale, with $14.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to HALO's 22.7%. On growth, HALO holds the edge at +51.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $1.4B | $14.9B |
| EBITDAEarnings before interest/tax | -$91M | -$112M | $945M | $4.2B |
| Net IncomeAfter-tax profit | -$80M | -$168M | $317M | $4.4B |
| Free Cash FlowCash after capex | -$79M | -$151M | $645M | $4.2B |
| Gross MarginGross profit ÷ Revenue | — | — | +81.9% | +84.5% |
| Operating MarginEBIT ÷ Revenue | — | — | +58.4% | +24.3% |
| Net MarginNet income ÷ Revenue | — | — | +22.7% | +29.6% |
| FCF MarginFCF ÷ Revenue | — | — | +46.2% | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +51.6% | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -16.7% | +91.5% | -2.1% | -7.2% |
Valuation Metrics
HALO leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 17.2x trailing earnings, REGN trades at a 31% valuation discount to HALO's 25.0x P/E. Adjusting for growth (PEG ratio), HALO offers better value at 1.09x vs REGN's 2.72x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $1.8B | $1690.08T | $7.6B | $74.3B |
| Enterprise ValueMkt cap + debt − cash | $1.8B | $1690.08T | $7.4B | $73.9B |
| Trailing P/EPrice ÷ TTM EPS | -22.14x | -0.75x | 25.05x | 17.23x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 7.96x | 15.46x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.09x | 2.72x |
| EV / EBITDAEnterprise value multiple | — | — | 8.20x | 17.92x |
| Price / SalesMarket cap ÷ Revenue | — | — | 5.41x | 5.18x |
| Price / BookPrice ÷ Book value/share | 5.31x | 0.65x | 162.76x | 2.48x |
| Price / FCFMarket cap ÷ FCF | — | — | 11.72x | 18.20x |
Profitability & Efficiency
HALO leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-130 for DBVT. MBX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DBVT's 0.13x. On the Piotroski fundamental quality scale (0–9), HALO scores 5/9 vs DBVT's 4/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -20.8% | -130.2% | +6.5% | +14.3% |
| ROA (TTM)Return on assets | -20.1% | -89.0% | +12.5% | +11.1% |
| ROICReturn on invested capital | -96.9% | — | +73.4% | +8.9% |
| ROCEReturn on capital employed | -40.4% | -145.7% | +38.2% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 4 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.00x | 0.13x | — | 0.09x |
| Net DebtTotal debt minus cash | -$49M | -$172M | -$134M | -$412M |
| Cash & Equiv.Liquid assets | $49M | $194M | $134M | $3.1B |
| Total DebtShort + long-term debt | $171,000 | $22M | $0 | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | — | -189.82x | 46.08x | 108.44x |
Total Returns (Dividends Reinvested)
Evenly matched — MBX and HALO each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in MBX five years ago would be worth $17,321 today (with dividends reinvested), compared to $3,172 for DBVT. Over the past 12 months, MBX leads with a +249.8% total return vs HALO's -5.3%. The 3-year compound annual growth rate (CAGR) favors HALO at 28.4% vs REGN's -1.5% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +34.1% | +3.6% | -8.8% | -7.8% |
| 1-Year ReturnPast 12 months | +249.8% | +100.5% | -5.3% | +31.2% |
| 3-Year ReturnCumulative with dividends | +73.2% | +18.1% | +111.8% | -4.4% |
| 5-Year ReturnCumulative with dividends | +73.2% | -68.3% | +39.1% | +43.2% |
| 10-Year ReturnCumulative with dividends | +73.2% | -87.1% | +559.7% | +91.6% |
| CAGR (3Y)Annualised 3-year return | +20.1% | +5.7% | +28.4% | -1.5% |
Risk & Volatility
Evenly matched — MBX and HALO each lead in 1 of 2 comparable metrics.
Risk & Volatility
HALO is the less volatile stock with a 0.51 beta — it tends to amplify market swings less than MBX's 1.33 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MBX currently trades 91.3% from its 52-week high vs DBVT's 75.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.33x | 1.26x | 0.51x | 0.77x |
| 52-Week HighHighest price in past year | $44.89 | $26.18 | $82.22 | $821.11 |
| 52-Week LowLowest price in past year | $9.43 | $7.53 | $47.50 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +91.3% | +75.3% | +78.0% | +87.1% |
| RSI (14)Momentum oscillator 0–100 | 61.6 | 47.4 | 47.7 | 41.7 |
| Avg Volume (50D)Average daily shares traded | 520K | 252K | 1.4M | 626K |
Analyst Outlook
REGN leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: MBX as "Buy", DBVT as "Buy", HALO as "Buy", REGN as "Buy". Consensus price targets imply 134.8% upside for DBVT (target: $46) vs 17.9% for HALO (target: $76). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $55.33 | $46.33 | $75.60 | $865.68 |
| # AnalystsCovering analysts | 4 | 15 | 27 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +0.5% |
| Dividend StreakConsecutive years of raises | — | 0 | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +4.5% | +5.3% |
HALO leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). REGN leads in 1 (Analyst Outlook). 2 tied.
MBX vs DBVT vs HALO vs REGN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MBX or DBVT or HALO or REGN a better buy right now?
For growth investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger pick with 37. 6% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Regeneron Pharmaceuticals, Inc. (REGN) offers the better valuation at 17. 2x trailing P/E (15. 5x forward), making it the more compelling value choice. Analysts rate MBX Biosciences, Inc. Common Stock (MBX) a "Buy" — based on 4 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MBX or DBVT or HALO or REGN?
On trailing P/E, Regeneron Pharmaceuticals, Inc.
(REGN) is the cheapest at 17. 2x versus Halozyme Therapeutics, Inc. at 25. 0x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Halozyme Therapeutics, Inc. wins at 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 44x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — MBX or DBVT or HALO or REGN?
Over the past 5 years, MBX Biosciences, Inc.
Common Stock (MBX) delivered a total return of +73. 2%, compared to -68. 3% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: HALO returned +559. 7% versus DBVT's -87. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MBX or DBVT or HALO or REGN?
By beta (market sensitivity over 5 years), Halozyme Therapeutics, Inc.
(HALO) is the lower-risk stock at 0. 51β versus MBX Biosciences, Inc. Common Stock's 1. 33β — meaning MBX is approximately 159% more volatile than HALO relative to the S&P 500. On balance sheet safety, MBX Biosciences, Inc. Common Stock (MBX) carries a lower debt/equity ratio of 0% versus 13% for DBV Technologies S. A. — giving it more financial flexibility in a downturn.
05Which is growing faster — MBX or DBVT or HALO or REGN?
By revenue growth (latest reported year), Halozyme Therapeutics, Inc.
(HALO) is pulling ahead at 37. 6% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Regeneron Pharmaceuticals, Inc. grew EPS 8. 2% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, HALO leads at 28. 4% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MBX or DBVT or HALO or REGN?
Regeneron Pharmaceuticals, Inc.
(REGN) is the more profitable company, earning 31. 4% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 31. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — REGN leads at 85. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MBX or DBVT or HALO or REGN more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Halozyme Therapeutics, Inc. (HALO) is the more undervalued stock at a PEG of 0. 35x versus Regeneron Pharmaceuticals, Inc. 's 2. 44x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 0x forward P/E versus 15. 5x for Regeneron Pharmaceuticals, Inc. — 7. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 134. 8% to $46. 33.
08Which pays a better dividend — MBX or DBVT or HALO or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. MBX, DBVT, HALO do not pay a meaningful dividend and should not be held primarily for income.
09Is MBX or DBVT or HALO or REGN better for a retirement portfolio?
For long-horizon retirement investors, Halozyme Therapeutics, Inc.
(HALO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 51), +559. 7% 10Y return). Both have compounded well over 10 years (HALO: +559. 7%, DBVT: -87. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MBX and DBVT and HALO and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: MBX is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; HALO is a small-cap high-growth stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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